JP2008500279A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008500279A5 JP2008500279A5 JP2006554230A JP2006554230A JP2008500279A5 JP 2008500279 A5 JP2008500279 A5 JP 2008500279A5 JP 2006554230 A JP2006554230 A JP 2006554230A JP 2006554230 A JP2006554230 A JP 2006554230A JP 2008500279 A5 JP2008500279 A5 JP 2008500279A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- cells
- peptide
- cell
- endogenously
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54676404P | 2004-02-23 | 2004-02-23 | |
| US60/546,764 | 2004-02-23 | ||
| PCT/US2005/005198 WO2005082939A2 (en) | 2004-02-23 | 2005-02-17 | Anti-abeta antibody |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008500279A JP2008500279A (ja) | 2008-01-10 |
| JP2008500279A5 true JP2008500279A5 (enExample) | 2008-03-06 |
| JP4851348B2 JP4851348B2 (ja) | 2012-01-11 |
Family
ID=34910810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006554230A Expired - Fee Related JP4851348B2 (ja) | 2004-02-23 | 2005-02-17 | 抗Ａβ抗体 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20070190046A1 (enExample) |
| EP (1) | EP1720909B1 (enExample) |
| JP (1) | JP4851348B2 (enExample) |
| KR (2) | KR100889430B1 (enExample) |
| CN (1) | CN1922209B (enExample) |
| AT (1) | ATE534667T1 (enExample) |
| AU (1) | AU2005217596B2 (enExample) |
| BR (1) | BRPI0507856A (enExample) |
| CA (1) | CA2556436C (enExample) |
| CY (1) | CY1112162T1 (enExample) |
| DK (1) | DK1720909T3 (enExample) |
| EA (1) | EA009872B1 (enExample) |
| ES (1) | ES2375627T3 (enExample) |
| IL (1) | IL177611A (enExample) |
| NO (1) | NO20064239L (enExample) |
| PL (1) | PL1720909T3 (enExample) |
| PT (1) | PT1720909E (enExample) |
| SI (1) | SI1720909T1 (enExample) |
| UA (1) | UA93181C2 (enExample) |
| WO (1) | WO2005082939A2 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| RU2442793C2 (ru) | 2005-11-30 | 2012-02-20 | Эбботт Лэборетриз | АНТИТЕЛА ПРОТИВ ГЛОБУЛОМЕРА Аβ, ИХ АНТИГЕНСВЯЗЫВАЮЩИЕ ЧАСТИ, СООТВЕТСТВУЮЩИЕ ГИБРИДОМЫ, НУКЛЕИНОВЫЕ КИСЛОТЫ, ВЕКТОРЫ, КЛЕТКИ-ХОЗЯЕВА, СПОСОБЫ ПОЛУЧЕНИЯ УКАЗАННЫХ АНТИТЕЛ, КОМПОЗИЦИИ, СОДЕРЖАЩИЕ УКАЗАННЫЕ АНТИТЕЛА, ПРИМЕНЕНИЯ УКАЗАННЫХ АНТИТЕЛ И СПОСОБЫ ИСПОЛЬЗОВАНИЯ УКАЗАННЫХ АНТИТЕЛ |
| PL1976877T5 (pl) | 2005-11-30 | 2017-09-29 | Abbvie Inc | Przeciwciała monoklonalne przeciwko białku amyloidu beta oraz ich zastosowania |
| NZ568012A (en) | 2005-12-12 | 2012-07-27 | Ac Immune Sa | A beta 1-42 specific monoclonal antibodies with therapeutic properties |
| RU2498999C2 (ru) | 2006-07-14 | 2013-11-20 | Ац Иммуне Са | Гуманизированное антитело к амилоиду бета |
| US8455626B2 (en) * | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| HUE033325T2 (en) * | 2007-01-05 | 2017-11-28 | Univ Zuerich | Anti-beta-amyloid binder antibodies and their use |
| HRP20140049T1 (hr) | 2007-01-05 | 2014-02-28 | University Of Zürich | Anti beta-amiloid antitijela i njihova upotreba |
| ES2610474T3 (es) | 2007-01-11 | 2017-04-27 | Michael Bacher | Diagnóstico y tratamiento de la enfermedad de Alzheimer y otras enfermedades neurodegenerativas causantes de demencia |
| US8895004B2 (en) | 2007-02-27 | 2014-11-25 | AbbVie Deutschland GmbH & Co. KG | Method for the treatment of amyloidoses |
| US8048420B2 (en) * | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
| US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
| PL2238166T3 (pl) | 2007-10-05 | 2014-07-31 | Genentech Inc | Zastosowanie przeciwciała anty-Beta amyloidowego w chorobach oczu |
| AU2008311366B2 (en) * | 2007-10-05 | 2015-03-12 | Ac Immune S.A. | Use of anti-amyloid beta antibody in ocular diseases |
| EP2376120A2 (en) | 2008-11-25 | 2011-10-19 | Biogen Idec MA Inc. | Use of dr6 and p75 antagonists to promote survival of cells of the nervous system |
| HRP20150831T1 (hr) | 2008-12-19 | 2015-10-09 | Biogen International Neuroscience Gmbh | Humana anti-alfa- sinuklein auto-protutijela |
| BR112012009997A2 (pt) | 2009-11-12 | 2019-09-24 | Genentech Inc | ''método para aumentar a densidade de espinhas dentriticas nos neurônios de um paciente com um distúrbios cognitivo ou psiquiatrico,método de manutenção da cognição em um sujeito durante o processo de envelhecimento,uso de um antagonista de dr6 na preparação de um medicamento para uso em um paciente com um disturbio cognitivo uo psiquíatrico e uso de um antagonista de p75 na preparação de um medicamento para uso em um paciente com um distúrbio cognitivo ou psiquiátrico'' |
| WO2011130377A2 (en) | 2010-04-15 | 2011-10-20 | Abbott Laboratories | Amyloid-beta binding proteins |
| US9221900B2 (en) | 2010-07-30 | 2015-12-29 | Ac Immune S.A. | Methods for identifying safe and functional humanized antibodies |
| SI3339323T1 (sl) * | 2010-08-12 | 2019-12-31 | Eli Lilly And Company | Protitelesa proti N3PGLU amiloid beta peptidu in njihove uporabe |
| US9062101B2 (en) | 2010-08-14 | 2015-06-23 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| PL2723379T3 (pl) | 2011-06-23 | 2019-05-31 | Biogen Int Neuroscience Gmbh | Cząsteczki wiążące przeciwko alfa-synukleinie |
| EP2892506B1 (en) | 2012-09-07 | 2021-11-03 | Massachusetts Eye & Ear Infirmary | Treating hearing loss with the gamma-secretase inhibitor ly411575 |
| CA2884309A1 (en) | 2012-09-07 | 2014-03-13 | Massachusetts Eye And Ear Infirmary | Methods and compositions for regenerating hair cells and/or supporting cells from differentiated cochlear cells or differentiated utricular cells by modulation of notch and cmyc activity |
| SG11201601823TA (en) | 2013-09-13 | 2016-04-28 | Genentech Inc | Methods and compositions comprising purified recombinant polypeptides |
| MA41115A (fr) | 2014-12-02 | 2017-10-10 | Biogen Int Neuroscience Gmbh | Procédé de traitement de la maladie d'alzheimer |
| KR102362222B1 (ko) | 2016-05-16 | 2022-02-11 | 더 제너럴 하스피탈 코포레이션 | 폐 상피 공학에서 인간 기도 줄기 세포 |
| JP2019524788A (ja) * | 2016-08-11 | 2019-09-05 | イーライ リリー アンド カンパニー | アミノチアジンおよびｂａｃｅ１阻害剤としてのそれらの使用 |
| MD3672631T3 (ro) | 2017-08-22 | 2023-09-30 | Biogen Ma Inc | Compoziții farmaceutice conținând anticorpi anti-beta amiloidici |
| TWI843040B (zh) | 2021-01-11 | 2024-05-21 | 美商美國禮來大藥廠 | 抗N3pGlu類澱粉β抗體及其用途 |
| WO2022251048A1 (en) | 2021-05-24 | 2022-12-01 | Eli Lilly And Company | Anti-amyloid beta antibodies and uses thereof |
| CA3243602A1 (en) | 2022-02-03 | 2023-08-10 | Eli Lilly And Company | Regional Tau Imaging for the Diagnosis and Treatment of Alzheimer's Disease |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA9711537B (en) | 1996-12-23 | 1998-06-25 | Athena Neurosciences Inc Eli L | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting ß-amyloid peptide release and/or its synthesis by use of such compounds. |
| US6518011B1 (en) * | 1999-01-13 | 2003-02-11 | Bristol-Myers Squibb Company | Method for screening compounds to identify beta-amyloid production modulators |
| EA006606B1 (ru) * | 2000-02-24 | 2006-02-24 | Вашингтон Юниверсити | Гуманизированное антитело и его фрагмент, взаимодействующие с бета-амилоидным пептидом, и способы их применения |
| AU5702201A (en) * | 2000-04-13 | 2001-10-30 | Mayo Foundation | Abeta<sub>42</sub> lowering agents |
| PE20020574A1 (es) * | 2000-12-06 | 2002-07-02 | Wyeth Corp | Anticuerpos humanizados que reconocen el peptido amiloideo beta |
| AU2002258808A1 (en) * | 2001-04-30 | 2002-11-11 | Eli Lilly And Company | Humanized antibodies |
-
2005
- 2005-02-17 JP JP2006554230A patent/JP4851348B2/ja not_active Expired - Fee Related
- 2005-02-17 US US10/590,411 patent/US20070190046A1/en not_active Abandoned
- 2005-02-17 DK DK05723280.3T patent/DK1720909T3/da active
- 2005-02-17 EP EP05723280A patent/EP1720909B1/en not_active Expired - Lifetime
- 2005-02-17 UA UAA200609258A patent/UA93181C2/ru unknown
- 2005-02-17 AT AT05723280T patent/ATE534667T1/de active
- 2005-02-17 KR KR1020067016812A patent/KR100889430B1/ko not_active Expired - Fee Related
- 2005-02-17 ES ES05723280T patent/ES2375627T3/es not_active Expired - Lifetime
- 2005-02-17 SI SI200531422T patent/SI1720909T1/sl unknown
- 2005-02-17 BR BRPI0507856-3A patent/BRPI0507856A/pt not_active IP Right Cessation
- 2005-02-17 CA CA2556436A patent/CA2556436C/en not_active Expired - Fee Related
- 2005-02-17 PL PL05723280T patent/PL1720909T3/pl unknown
- 2005-02-17 PT PT05723280T patent/PT1720909E/pt unknown
- 2005-02-17 AU AU2005217596A patent/AU2005217596B2/en not_active Ceased
- 2005-02-17 EA EA200601545A patent/EA009872B1/ru not_active IP Right Cessation
- 2005-02-17 CN CN2005800056858A patent/CN1922209B/zh not_active Expired - Fee Related
- 2005-02-17 KR KR1020087031635A patent/KR20090005410A/ko not_active Ceased
- 2005-02-17 WO PCT/US2005/005198 patent/WO2005082939A2/en not_active Ceased
-
2006
- 2006-08-21 IL IL177611A patent/IL177611A/en not_active IP Right Cessation
- 2006-09-19 NO NO20064239A patent/NO20064239L/no not_active Application Discontinuation
-
2011
- 2011-12-21 CY CY20111101276T patent/CY1112162T1/el unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Diller et al. | The role of the extracellular matrix (ECM) in wound healing: a review | |
| Meier et al. | Interleukin-1 receptor antagonist modulates liver inflammation and fibrosis in mice in a model-dependent manner | |
| Joo et al. | Advanced lung organoids for respiratory system and pulmonary disease modeling | |
| Marchioni et al. | Pulmonary stretch and lung mechanotransduction: implications for progression in the fibrotic lung | |
| Sun et al. | Current perspectives on nucleus pulposus fibrosis in disc degeneration and repair | |
| Dai et al. | Vascular remodeling: the multicellular mechanisms of pulmonary hypertension | |
| Boateng et al. | Evaluation of clay-functionalized wafers and films for nicotine replacement therapy via buccal mucosa | |
| Bateman et al. | Airway epithelium senescence as a driving mechanism in COPD pathogenesis | |
| Petrini et al. | Influence of nano, micro, and macro topography of dental implant surfaces on human gingival fibroblasts | |
| WO2007077217A3 (en) | Oligopeptide-free cell culture media | |
| ATE539145T1 (de) | Verfahren zum erhalt von mesenchymalen stammzellen | |
| Loukelis et al. | Kappa-carrageenan/chitosan/gelatin scaffolds provide a biomimetic microenvironment for dentin-pulp regeneration | |
| Gehrke et al. | New implant macrogeometry to improve and accelerate the osseointegration: an in vivo experimental study | |
| Zhou et al. | Fabrication of fibrin/polyvinyl alcohol scaffolds for skin tissue engineering via emulsion templating | |
| Lettieri et al. | The plastic interplay between lung regeneration phenomena and fibrotic evolution: current challenges and novel therapeutic perspectives | |
| Syenina et al. | Th1-polarized, dengue virus-activated human mast cells induce endothelial transcriptional activation and permeability | |
| Shimizu et al. | Observation of chronic graft-versus-host disease mouse model cornea with in vivo confocal microscopy | |
| Gaddam et al. | Cystathionine-Gamma-Lyase-Derived hydrogen sulfide-regulated substance P modulates liver sieve fenestrations in Caecal ligation and puncture-induced sepsis | |
| Zeissig et al. | Tumour dissemination in multiple myeloma disease progression and relapse: a potential therapeutic target in high-risk myeloma | |
| Haas et al. | Recovery of altered diabetic myofibroblast heterogeneity and gene expression are associated with CD301b+ macrophages | |
| Wyganowska-Swiatkowska et al. | Atelocollagen application in human periodontal tissue treatment—A pilot study | |
| Volloch et al. | Next Generation Therapeutic Strategy for Treatment and Prevention of Alzheimer’s Disease and Aging-Associated Cognitive Decline: Transient, Once-in-a-Lifetime-Only Depletion of Intraneuronal Aβ (i Aβ) by Its Targeted Degradation via Augmentation of Intra-i Aβ-Cleaving Activities of BACE1 and/or BACE2 | |
| EP1687413A4 (en) | Method for differentiating mesenchymal stem cell into neural cell and pharmaceutical composition containing the neural cell for neurodegenerative disease | |
| Salim et al. | Oncostatin M receptor type II knockout mitigates inflammation and improves survival from sepsis in mice | |
| Baus-Domínguez et al. | Biological response of the peri-implant mucosa to different definitive implant rehabilitation materials |