JP2008286651A5 - - Google Patents
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- Publication number
- JP2008286651A5 JP2008286651A5 JP2007132239A JP2007132239A JP2008286651A5 JP 2008286651 A5 JP2008286651 A5 JP 2008286651A5 JP 2007132239 A JP2007132239 A JP 2007132239A JP 2007132239 A JP2007132239 A JP 2007132239A JP 2008286651 A5 JP2008286651 A5 JP 2008286651A5
- Authority
- JP
- Japan
- Prior art keywords
- polyamine
- polyamine oxidase
- content
- protein
- interleukin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102100037209 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase Human genes 0.000 claims 20
- 108010089000 polyamine oxidase Proteins 0.000 claims 20
- HGINCPLSRVDWNT-UHFFFAOYSA-N Acrolein Chemical compound C=CC=O HGINCPLSRVDWNT-UHFFFAOYSA-N 0.000 claims 10
- 108010074051 C-Reactive Protein Proteins 0.000 claims 10
- 102100032752 C-reactive protein Human genes 0.000 claims 10
- 102000004889 Interleukin-6 Human genes 0.000 claims 10
- 108090001005 Interleukin-6 Proteins 0.000 claims 10
- 239000012472 biological sample Substances 0.000 claims 10
- 206010008118 cerebral infarction Diseases 0.000 claims 10
- 230000000694 effects Effects 0.000 claims 10
- 229940100601 interleukin-6 Drugs 0.000 claims 10
- 238000000034 method Methods 0.000 claims 9
- 150000001299 aldehydes Chemical class 0.000 claims 5
- 229920000768 polyamine Polymers 0.000 claims 5
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 238000007619 statistical method Methods 0.000 claims 4
- 238000013528 artificial neural network Methods 0.000 claims 2
- 208000026106 cerebrovascular disease Diseases 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 230000035945 sensitivity Effects 0.000 claims 1
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007132239A JP5339227B2 (ja) | 2007-05-18 | 2007-05-18 | アクロレイン、インターロイキン−６及びｃｒｐの含有量、ポリアミンオキシダーゼ活性又はポリアミンオキシダーゼの蛋白質量、並びに、被験者の年齢を指標とした脳卒中・無症候性脳梗塞の検出方法 |
| US12/598,125 US20100167322A1 (en) | 2007-05-18 | 2008-02-19 | Method of detecting cerebral stroke or asymptomatic cerebral infarction using acrolein, interleukin-6 and crp contents, polyamine oxidase activity or polyamine oxidase protein content and subject's age as indicators |
| PCT/JP2008/052701 WO2008142888A1 (ja) | 2007-05-18 | 2008-02-19 | アクロレイン、インターロイキン－６及びcrpの含有量、ポリアミンオキシダーゼ活性又はポリアミンオキシダーゼの蛋白質量、並びに、被験者の年齢を指標とした脳卒中・無症候性脳梗塞の検出方法 |
| EP08711525A EP2163645B1 (en) | 2007-05-18 | 2008-02-19 | Method of detecting cerebral stroke or asymptomatic cerebral infarction using acrolein, interleukin-6 and crp contents, polyamine oxidase activity or polyamine oxidase protein content and subject's age as indications |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007132239A JP5339227B2 (ja) | 2007-05-18 | 2007-05-18 | アクロレイン、インターロイキン−６及びｃｒｐの含有量、ポリアミンオキシダーゼ活性又はポリアミンオキシダーゼの蛋白質量、並びに、被験者の年齢を指標とした脳卒中・無症候性脳梗塞の検出方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008286651A JP2008286651A (ja) | 2008-11-27 |
| JP2008286651A5 true JP2008286651A5 (enExample) | 2010-07-01 |
| JP5339227B2 JP5339227B2 (ja) | 2013-11-13 |
Family
ID=40031607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007132239A Expired - Fee Related JP5339227B2 (ja) | 2007-05-18 | 2007-05-18 | アクロレイン、インターロイキン−６及びｃｒｐの含有量、ポリアミンオキシダーゼ活性又はポリアミンオキシダーゼの蛋白質量、並びに、被験者の年齢を指標とした脳卒中・無症候性脳梗塞の検出方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20100167322A1 (enExample) |
| EP (1) | EP2163645B1 (enExample) |
| JP (1) | JP5339227B2 (enExample) |
| WO (1) | WO2008142888A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2012067150A1 (ja) * | 2010-11-16 | 2014-05-12 | 三菱化学株式会社 | Ｉｎｔｅｒｌｅｕｋｉｎ−６ｒｅｃｅｐｔｏｒｓｕｂｕｎｉｔｂｅｔａ蛋白質による脳梗塞の検査方法 |
| JP6499342B2 (ja) * | 2018-03-19 | 2019-04-10 | 隆樹 日和佐 | 脳梗塞の診断マーカー |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3081043B2 (ja) * | 1991-12-27 | 2000-08-28 | シスメックス株式会社 | 脳梗塞の診断方法 |
| JP3609014B2 (ja) | 2000-09-22 | 2005-01-12 | 善行 澤田 | 気体溶解装置 |
| WO2003016910A1 (en) | 2001-08-20 | 2003-02-27 | Biosite, Inc. | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
| JP4426929B2 (ja) * | 2004-03-25 | 2010-03-03 | 株式会社アミンファーマ研究所 | 脳卒中・無症候性脳梗塞のスクリーニング方法 |
-
2007
- 2007-05-18 JP JP2007132239A patent/JP5339227B2/ja not_active Expired - Fee Related
-
2008
- 2008-02-19 EP EP08711525A patent/EP2163645B1/en not_active Not-in-force
- 2008-02-19 WO PCT/JP2008/052701 patent/WO2008142888A1/ja not_active Ceased
- 2008-02-19 US US12/598,125 patent/US20100167322A1/en not_active Abandoned
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