JP2007248395A5 - - Google Patents
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- Publication number
- JP2007248395A5 JP2007248395A5 JP2006075498A JP2006075498A JP2007248395A5 JP 2007248395 A5 JP2007248395 A5 JP 2007248395A5 JP 2006075498 A JP2006075498 A JP 2006075498A JP 2006075498 A JP2006075498 A JP 2006075498A JP 2007248395 A5 JP2007248395 A5 JP 2007248395A5
- Authority
- JP
- Japan
- Prior art keywords
- acute coronary
- coronary syndrome
- adamts13
- amount
- von willebrand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000004476 Acute Coronary Syndrome Diseases 0.000 claims 36
- 108010047303 von Willebrand Factor Proteins 0.000 claims 34
- 102100036537 von Willebrand factor Human genes 0.000 claims 30
- 229960001134 von willebrand factor Drugs 0.000 claims 30
- 102100032290 A disintegrin and metalloproteinase with thrombospondin motifs 13 Human genes 0.000 claims 17
- 108091005670 ADAMTS13 Proteins 0.000 claims 17
- 238000000034 method Methods 0.000 claims 15
- 201000010099 disease Diseases 0.000 claims 14
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 14
- 230000000694 effects Effects 0.000 claims 12
- 102000004190 Enzymes Human genes 0.000 claims 10
- 108090000790 Enzymes Proteins 0.000 claims 10
- 230000000593 degrading effect Effects 0.000 claims 7
- 238000001514 detection method Methods 0.000 claims 7
- 239000003153 chemical reaction reagent Substances 0.000 claims 6
- 238000012544 monitoring process Methods 0.000 claims 4
- 230000001502 supplementing effect Effects 0.000 claims 4
- 235000009421 Myristica fragrans Nutrition 0.000 claims 3
- 239000001115 mace Substances 0.000 claims 3
- 238000003745 diagnosis Methods 0.000 claims 2
- 238000004393 prognosis Methods 0.000 claims 2
- 230000009469 supplementation Effects 0.000 claims 2
- 238000011156 evaluation Methods 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 230000001575 pathological effect Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006075498A JP4820192B2 (ja) | 2006-03-17 | 2006-03-17 | 急性冠症候群でのａｄａｍｔｓ１３の測定と利用 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006075498A JP4820192B2 (ja) | 2006-03-17 | 2006-03-17 | 急性冠症候群でのａｄａｍｔｓ１３の測定と利用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007248395A JP2007248395A (ja) | 2007-09-27 |
| JP2007248395A5 true JP2007248395A5 (enExample) | 2009-04-23 |
| JP4820192B2 JP4820192B2 (ja) | 2011-11-24 |
Family
ID=38592839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006075498A Active JP4820192B2 (ja) | 2006-03-17 | 2006-03-17 | 急性冠症候群でのａｄａｍｔｓ１３の測定と利用 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4820192B2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2484897C (en) | 2002-05-09 | 2015-10-06 | The Brigham And Women's Hospital, Inc. | Soluble st2 as a cardiovascular disease marker and therapeutic target |
| CA2650201C (en) | 2006-04-24 | 2020-10-20 | James V. Snider | Predicting mortality and detecting severe disease |
| JP5377289B2 (ja) | 2006-05-01 | 2013-12-25 | クリティカル ケア ダイアグノスティクス インコーポレイテッド | 心血管疾患の診断方法 |
| EP2374878B1 (en) | 2007-06-22 | 2015-08-19 | The Chemo-Sero-Therapeutic Research Institute | Novel adamts-13 mutant |
| HUE029880T2 (en) * | 2008-04-18 | 2017-04-28 | Critical Care Diagnostics Inc | Predicting the risk of serious heart events |
| AU2009322367B2 (en) | 2008-12-05 | 2015-03-26 | Takeda Pharmaceutical Company Limited | Methods of measuring ADAMTS13-mediated in vivo cleavage of von Willebrand factor and uses thereof |
| US8501420B2 (en) * | 2009-08-31 | 2013-08-06 | Abbott Laboratories | Biomarkers for prediction of major adverse cardiac events and uses thereof |
| WO2014031764A1 (en) | 2012-08-21 | 2014-02-27 | Critical Care Diagnostics, Inc. | Multimarker risk stratification |
| CN103808944B (zh) * | 2014-03-07 | 2016-04-20 | 高平 | 生物标志物vwf和adamts13及其在肝硬化诊断试剂中的用途 |
| JP2019532649A (ja) | 2016-10-11 | 2019-11-14 | ラボラトリー コーポレイション オブ アメリカ ホールディングス | Ａｄａｍｔｓ１３酵素活性を決定するための方法およびシステム |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000024781A1 (en) * | 1998-10-23 | 2000-05-04 | The Brigham And Women's Hospital, Inc. | Conformation-specific anti-von willebrand factor antibodies |
| JP4666942B2 (ja) * | 2003-04-25 | 2011-04-06 | 学校法人慶應義塾 | フォンビルブラント因子切断酵素遺伝子解析による血栓性疾患関連の遺伝子変異検出方法 |
| JP5112692B2 (ja) * | 2003-07-07 | 2013-01-09 | ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル | フォンビルブランド因子（ｖｗｆ）マルチマーを検出する方法およびシステム |
| JP4398188B2 (ja) * | 2003-07-09 | 2010-01-13 | 積水メディカル株式会社 | 急性冠症候群およびその病態の検査方法 |
| JP4621593B2 (ja) * | 2003-12-22 | 2011-01-26 | 三菱化学メディエンス株式会社 | フォンヴィルブランド因子分解酵素の測定による血栓症の検出方法 |
-
2006
- 2006-03-17 JP JP2006075498A patent/JP4820192B2/ja active Active
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