JP2008230112A - Laminated material and packaging body - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a laminated material and a packaging body each accommodating a medical supply and a medical gear such as an ampoule, a syringe, a medicine or various foods or the like, and enabling the accommodated item to be visible and shielding light of a specific wavelength. <P>SOLUTION: The laminated material includes at least a layer composed of a polyolefine-ethylene vinyl alcohol copolymer wherein all light transmission factor of the laminated material at a wavelength of 380 nm is not more than 1%, all light transmission factor thereof at a wavelength of 500 nm is not more than 5%, and all light transmission factor thereof at a wavelength of 600 nm is not less than 70%. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to a laminated material and a package for storing pharmaceuticals such as ampoules, syringes, medicines, medical supplies, and various foods. Specifically, the present invention relates to a laminated material and a package that have a function of blocking a light beam having a specific wavelength, in which a stored item is visible.

  Conventionally, many laminated materials, packaging methods, and packaging techniques for storing pharmaceuticals, medical supplies, various foods, and the like have been known and proposed. For example, a lid made of a plastic sheet having recesses (hereinafter sometimes referred to as pockets), containing a medicine such as a capsule tablet in each recess, and made entirely of aluminum foil, an easily openable plastic sheet or paper PTP packaging covered with material is known.

  And the plastic sheet which has the said recessed part is called blister bottom material, and the vinyl chloride resin sheet was used conventionally. However, as a vinyl chloride resin sheet, a polypropylene sheet or an amorphous polyester sheet has recently been used from the viewpoint of environmental protection due to problems such as generation of chlorine gas during incineration and dioxin.

  In addition, the visibility of stored items is generally required for PTP packaging and blister packaging. For this reason, since a polypropylene-type sheet | seat and an amorphous polyester-type sheet | seat are transparent, they are excellent in visibility and are used abundantly.

  However, there are many demands for laminated materials and the like that prevent deterioration due to ultraviolet rays or oxidation in medicines, medical supplies, and various foods stored in PTP packaging, blister packaging, and the like. For example, as a laminated material for pharmaceuticals and medical supplies, a laminated material having a function of blocking light having a specific wavelength (light shielding property) is required.

  Further, as described above, many packaging materials for pharmaceuticals and medical supplies have been proposed and are known. For example, a blister bottom material (see, for example, Patent Document 1) used for PTP packaging improved for safely storing medicines and foods is known.

  This blister bottom material is a blister bottom material formed by laminating a plurality of resin layers, and has an ultraviolet blocking layer between resin layers.

  In addition, as gas-barrier foods and medical containers, gas barrier properties that can be manufactured in a short time even when laminated at a low temperature, while maintaining a sufficiently satisfactory level of adhesion between the layers. A food / medical container and a method for producing the same are also known (for example, see Patent Document 2).

This gas barrier food / medical container is composed of a laminate having a paper layer, a resin layer, and a gas barrier layer. The resin layer has a layer made of a polyolefin resin composition containing (A) a polyolefin resin and (B) a compound having an intramolecular unsaturated bond, and the molecule in the polyolefin resin composition The number of inner unsaturated bonds is 0.5 or more per 10 ³ carbons.

  Further, an ultraviolet absorbing package material that is not transparent to ultraviolet rays or visible light and is visible from the outside as a medical material (see, for example, Patent Document 3) is also known.

This ultraviolet absorbing package material is formed of first and second films. The first film is optically transparent, first have a thickness, the moisture permeability of not more than 20 g / m ^2/24 hours, said second film, said first thickness is a second thickness of less, it has a light transmittance UV-absorbing film, such as its moisture permeability is at 20 g / m ^2/24 hours or more, the first and second films after sterilization It is characterized by forming a laminate having almost no wrinkles.

Prior art documents are shown below.
JP 2000-289139 A JP 2000-108277 A JP-A-8-84768

  By the way, the blister bottom material of Patent Document 1 has a plurality of resin layers laminated as described above, and an ultraviolet blocking layer is formed between the resin layers. The plurality of resin layers are made of, for example, a resin such as polypropylene whose main component is a common resin.

  Moreover, it is not specified that an oxygen barrier (blocking) resin layer or the like normally required for packaging materials for pharmaceuticals or medical supplies is provided. For this reason, the blister bottom material has either a structure in which an oxygen barrier (blocking) resin layer or the like is not provided, or an oxygen barrier (blocking) resin in which a plurality of resin layers are common to each other is used as a main component. Is formed. When the oxygen barrier (blocking) resin is not provided, there is a problem that the storage stability of the stored item is deteriorated. When the oxygen barrier (blocking) resin is provided, there is a problem that the blister bottom material becomes very expensive.

  In addition, blister bottom materials that use a resin whose main component is a common main component, such as polypropylene, do not have an oxygen barrier (blocking) property, so that stored medicines, medical supplies, various foods, etc. are oxidized. Or have a problem of deterioration.

  The structure of the gas barrier food / medical container of Patent Document 2 is formed of a paper layer, a resin layer, and a gas barrier layer. And it is a wonderful container as a container for foods and the like because it can be laminated at a low temperature and does not produce odor.

  However, since the paper layer is formed, there is a problem that the stored items cannot be seen. And when it uses as a medical container, there exists a problem of producing a medical error.

  Further, when used as a container for food or the like, moisture is absorbed from the edge portion of the paper layer by a sterilization process, a distribution method or a storage method after the stored item or the stored item is sealed. And there exists a problem that a laminated body delaminates.

Next, packaging material ultraviolet absorber described in Patent Document 3 is optically clear as described above, the moisture permeability of 20 g / m ^2/24 hours or less of the first film and the moisture permeability of 20 g / m ^2/24 or more hours the second film and is laminated. It is described that it is not transparent and is visible from the outside and can absorb ultraviolet rays having a wavelength of 285 to 358 nm.

  However, the shortwave wavelength region that can oxidize, degrade, or adversely affect many pharmaceuticals is usually high, and the wavelength region of 285 to 358 nm is insufficient to protect pharmaceuticals and the like.

  The present invention has been made in view of the above-described conventional problems, and the problem is that the stored object can be visually recognized without giving light-shielding property and the transparency is not deteriorated, and the quality of the stored object. The object is to provide a laminated material and a package that have good flexibility by shielding harmful wavelength rays and oxygen as factors causing the decrease.

In order to solve the above problems, the invention according to claim 1 of the present invention provides:
A laminated material in which at least a layer comprising polyolefin and an ethylene-vinyl alcohol copolymer is laminated,
The laminated material has a total light transmittance at a wavelength of 380 nm of 1% or less, a total light transmittance at a wavelength of 500 nm of 5% or less, and a total light transmittance at a wavelength of 600 nm of 70% or more. Laminated material.

Next, the invention according to claim 2 of the present invention is as follows:
A UV absorber or yellow pigment is kneaded in a part or all layers of the laminated material, and / or an ink in which the UV absorber or yellow pigment is dispersed is applied. The laminated material according to claim 1.

Next, the invention according to claim 3 of the present invention is
3. The amount or thickness of the ultraviolet absorber or yellow pigment to be kneaded or / and applied is appropriately selected depending on whether the outside is large or the inside is large. Laminated material.

Next, the invention according to claim 4 of the present invention is
The laminated material according to any one of claims 1 to 3, wherein the laminated material has a total thickness of 120 µm or more and 250 µm or less.

Next, the invention according to claim 5 of the present invention is
A package comprising the laminated material according to any one of claims 1 to 4 formed into a bag shape.

Next, the invention according to claim 6 of the present invention is
A package comprising the laminated material according to any one of claims 1 to 4 formed into a container shape.

  Since the laminated material and the package of the present invention are constituted as described above, harmful wavelength rays can be shielded. The stored items are not oxidized or deteriorated.

  Moreover, the laminated material and the package of the present invention have transparency and are excellent in visibility of stored items. Furthermore, it can be confirmed with a camera or the like as well as being able to visually check the quality of the stored items. And a sense of security can be given to the person who uses a storage thing.

  Moreover, the laminated material and the package of the present invention are excellent in oxygen barrier (shielding) properties as well as shielding harmful wavelength rays. The stored items are not oxidized or deteriorated.

  Furthermore, the laminated material and the package of the present invention are flexible and can be easily crushed when discarded. And it is easy to discard.

  The laminated material and package of the present invention will be described in detail below along the embodiments with reference to the drawings.

  FIG. 1 is an explanatory view showing a cross section of an embodiment of the laminated material of the present invention. Moreover, FIG. 2 is explanatory drawing which shows the cross section of other one Example of the laminated material of this invention. Furthermore, FIG. 3 is explanatory drawing which shows the cross section of another Example of the laminated material of this invention. Furthermore, FIG. 4 is explanatory drawing which shows the cross section of another one Example of the laminated material of this invention.

  As shown in FIG. 1, the laminated material 10 of the present embodiment is composed of a polyethylene resin layer 1 / adhesive resin layer 2 / ethylene-vinyl alcohol copolymer resin layer (EVOH) 3 / adhesive layer 13 / polyethylene resin layer 1. It has become.

  2 has a configuration of polypropylene resin layer 4 / adhesive resin layer 2 / ethylene-vinyl alcohol copolymer resin layer (EVOH) 3 / adhesive layer 13 / polypropylene resin layer 4. .

  When pinhole resistance is required depending on the stored items or distribution conditions, polyethylene resin layer 1 / adhesive resin layer 2 / nylon (polyamide) 5 / ethylene-vinyl alcohol as shown in FIG. A laminated material 30 having a constitution of copolymer resin layer (EVOH) 3 / nylon (polyamide) resin layer 5 / adhesive layer 13 / polyethylene resin layer 1 can be selected.

  Similarly to the above, when pinhole resistance is required, a polypropylene resin layer 4 / adhesive resin layer 2 / nylon (polyamide) 5 / ethylene-vinyl alcohol copolymer resin layer as shown in FIG. A laminated material 40 having a configuration of (EVOH) 3 / nylon (polyamide) resin layer 5 / adhesive layer 13 / polypropylene resin layer 4 can be selected.

  In the present embodiment, the resin layers shown in FIGS. 1 to 4 are kneaded with an ultraviolet absorber or a yellow pigment in some or all of the layers when forming each resin layer, or / In addition, an ink in which an ultraviolet absorber or a yellow pigment is dispersed is appropriately applied. The amount and thickness of kneading and application are appropriately selected depending on whether the outside is large or the inside is large.

  Laminate materials 10, 20, 30, and 40 in which the ultraviolet absorber and yellow pigment are kneaded or / and a resin layer or the like to which an ink in which the ultraviolet absorber or yellow pigment is dispersed are appropriately laminated are at a wavelength of 380 nm. The total light transmittance is 1% or less, the total light transmittance at a wavelength of 500 nm is 5% or less, and the total light transmittance at a wavelength of 600 nm is 70% or more.

  In addition, when kneading the ultraviolet absorber or yellow pigment, the amount of the ultraviolet absorber or yellow pigment is large on the outside or on the inside. It is appropriately selected depending on the above.

  Similarly, whether the coating amount of the ink in which the ultraviolet absorber or yellow pigment is dispersed is large on the outside or on the inside is selected as appropriate depending on the stored items, the distribution conditions of the stored items, the storage method, etc. Is done.

  When applying the ink in which the ultraviolet absorber or yellow pigment is dispersed, the roll coater, air knife coater, gravure coater, metering bar coater, fountain blade coater, bevel blade coater, short dwell coater or curtain coater are particularly limited. Although not, it can be formed using any suitable applicator.

  In addition, the method of laminating each of the resin layers constituting the laminated material 10, 20, 30, 40 of the present invention is a dry lamination method in which an adhesive such as a two-component curable urethane resin is used for bonding, and a solvent-free method. The lamination material of the present invention can be obtained by laminating by a known method such as laminating by a non-solvent lamination method in which bonding is performed using an adhesive or extruding lamination method in which a resin is heated and melted and extruded into a curtain shape. it can.

  The adhesive resin layer 13 formed by the extrusion lamination method is an adhesive thermoplastic resin that can be heat-sealed and can be melted by heat and fused to each other. Density polyethylene, medium density polyethylene, high density polyethylene, linear (linear) low density polyethylene, polypropylene, ethylene-vinyl acetate copolymer, ionomer resin, ethylene-ethyl acrylate copolymer, ethylene-acrylic acid copolymer Polymer, ethylene-methacrylic acid copolymer, ethylene-propylene copolymer, methyl pentene polymer, polyolefin resin such as polyethylene or polypropylene, acrylic acid, methacrylic acid, maleic acid, maleic anhydride, fumaric acid, Acid-modified polyols modified with unsaturated carboxylic acids such as itaconic acid It can be used fin-based resin other like resins. And although thickness is suitably determined according to the objective, generally it exists in the range of 15-50 micrometers.

  Further, as the adhesive of the adhesive layer 13, a two-component curing type vinyl-based, (meth) acrylic-based, polyamide-based, polyester-based, polyether-based, polyurethane-based, epoxy-based adhesive or the like is used. Although it can be used, a two-component curable urethane adhesive is preferably used.

  Examples of the adhesive coating method include direct gravure roll coating method, gravure roll coating method, kiss coating method, reverse roll coating method, Fonten method, transfer method, and the like. -It can apply | coat by methods, such as a roll coat method and others.

The coating amount is preferably about 0.1 to 10 g / m ² (dry state), more preferably 1 to 5 g / m ² (dry state).

Further, the ultraviolet absorber may be methanone having a chemical formula of C ₁₅ H ₁₄ O ₅ , bis (2-humanroxy-4-methoxyphenyl) or 2.2′-dihitroxy-4.4′-dimethoxybenzourephenone, Commonly used plastic molding, for example, benzophenone-based sea soap 101 (manufactured by Sipro Kasei Co., Ltd.), benzotriazole-based tinuvin P (manufactured by Ciba Geigy), salicylate-based bio soap 90 (manufactured by Kyodo Yakuhin), cyano In addition to acrylate-based biosoap 910 (manufactured by Kyodo Pharmaceutical Co., Ltd.), various ultraviolet absorbing materials are commercially available. A preferred UV absorbing material is UVINUL D-49, commercially available from BASF Corporation, Parsippany, New Jersey.

Specific examples of the resin material used as the nylon resin layer material for the nylon (polyamide) resin layer 5 include polycaproamide (nylon 6), poly-ω-aminoheptanoic acid (nylon 7), and poly-9. -Aminononanoic acid (nylon 9), polyundecanamide (nylon 11), polylaurin lactam (nylon 12), polyethylenediamine adipamide (nylon 2,6), polytetramethylene adipamide (nylon 4,6), poly Hexamethylenediadipamide (nylon 6,6), polyhexamethylene sebamide (nylon 6,10), polyhexamethylene dodecamide (nylon 6,12), polyoctamethylene adipamide (nylon 8,6), Polydecamethylene adipamide (nylon 10, 6), polydecamethylene sebamide Nylon 10,10), polydodecamethylene dodecamide (nylon 12,12), meta-xylene diamine -6 nylon (MXD6) and the like.

  As described above, the laminated materials 10, 20, 30, and 40 of the present invention are obtained by kneading the ultraviolet absorber or yellow pigment in each resin layer or a part of the resin layer or dispersing the ultraviolet absorber or yellow pigment. After applying the ink to each resin layer or a part of the resin layers, each resin layer is laminated. The total thickness of the laminated material is appropriately selected depending on the stored items or storage conditions, material configuration, distribution conditions, and the like, but is usually formed to be 120 μm or more and 250 μm or less.

  Further, the laminated materials 10, 20, 30, and 40 of the present invention can be used by forming into a bag shape or a container shape as shown in FIG. 9 or FIG. And after storing a storage thing by shape | molding in the shape of a bag or a container, the storage opening is sealed, so that the storage thing is oxidized or deteriorated, for example, deterioration of components such as vitamins contained in the storage thing, etc. Can also be prevented.

Examples of the stored items stored in the bag-shaped or container-shaped package include ampules, vials, blood bags, infusion bags, and the like as medical containers. And as a content, a medicine powder, a medicine grain, a medicine, an infusion, blood, etc. are stored. As various foods, dried foods and water foods such as water, dairy products, juice, liquor, coffee, tea, soy sauce, sauces, tofu and the like are accommodated.

  Further, the stored items stored in the bag-shaped or container-shaped package can be easily visually observed. And when a stored item is a medical article or a medical instrument, a medical error can be prevented.

  The bag-like package is a flat bag such as a two-sided or three-sided seal, a four-sided seal, a side seal or an envelope-attached seal, a seam-attached seal, or a boat bottom seal. Alternatively, a self-supporting packaging bag in which a bottom portion of a packaging bag such as a three-side seal or a four-side seal having a bottom seal portion at the bottom and side seal portions on both side end surfaces is widened forward and backward to form a rectangular flat bottom surface. Or the bag of packaging forms, such as a self-supporting packaging bag (standing pouch) which has a gusset part inside the bottom part of the front side and back side of a bag, is mentioned.

  Further, the molding method for forming into a container shape using the laminated materials 10, 20, 30, 4 of the present invention is a known plastic molding method such as a pressure forming method, a vacuum forming method, a vacuum pressure forming method or the like.

  Moreover, the lid | cover material which seals the accommodated opening part after accommodating a stored item in the molded object shape | molded by the container shape is not specifically limited. And the container formed in the container shape using the laminated material of the present invention, a heat-sealable resin sheet or film, and a resin sheet or film in which a metal foil layer such as aluminum foil or a vapor-deposited thin film layer is formed are laminated. Laminated sheets or films can be used.

  The laminated sheet or film may be kneaded with an ultraviolet absorber in a part or all of the resin sheet or film to be laminated, or / or coated with an ultraviolet cut ink and a transparent yellow ink containing the ultraviolet absorber. Is more preferable.

The resin of the heat-sealable resin sheet or film is an adhesive thermoplastic resin that can be heat-sealed, and any resin that can be melted by heat and fused to each other, such as low-density polyethylene, Density polyethylene, high density polyethylene, linear (linear) low density polyethylene, polypropylene, ethylene-vinyl acetate copolymer, ionomer resin, ethylene-ethyl acrylate copolymer, ethylene-acrylic acid copolymer, ethylene -Polyolefin resin such as methacrylic acid copolymer, ethylene-propylene copolymer, methylpentene polymer, polyethylene or polypropylene, acrylic acid, methacrylic acid, maleic acid, maleic anhydride, fumaric acid, itaconic acid, etc. Acid-modified polyolefin resin modified with unsaturated carboxylic acid such as It can be used in other of the resin.

Further, heat-sealable As the resin sheet or film resin, density 0.940 g / cm ³ or more high-density polyethylene resin (HDPE) or density of 0.930 g / cm ³ or more linear low density polyethylene resin ( LLDPE) is desirable.

  Examples of the laminated sheet or film resin for forming the vapor-deposited thin film layer include polyolefin (polyethylene, polypropylene, etc.), polyester (polyethylene terephthalate, polybutylene terephthalate, polyethylene naphthalate, etc.), polyamide (nylon 6, nylon 66, etc.), etc. Alternatively, a resin such as a copolymer of these polymers is used.

  In forming a deposited thin film layer, the surface of the resin sheet or film forming the deposited thin film layer is subjected to corona treatment, low temperature plasma treatment, plasma treatment using reactive ion etching (RIE), ion bombardment treatment, chemicals. Any treatment such as treatment or solvent treatment may be performed.

  In addition, examples of the metal oxide constituting the deposited thin film layer include metal oxides composed of simple substances such as silicon, aluminum, titanium, zirconium, and tin, or composites thereof. Aluminum oxide, silicon oxide Magnesium oxide alone or a composite thereof is preferably used.

  The optimum thickness of the vapor-deposited thin film layer varies depending on the type and configuration of the metal oxide used, but generally it is preferably in the range of 5 to 300 nm, and the value is appropriately selected.

  Next, in the package formed into a bag shape or a container shape using the laminated material of the present invention, a printed layer is formed although it is not shown in the drawing because the package is naturally used practically.

  As the printing layer, for example, an ordinary gravure ink composition, a screen ink composition, or other ink composition is used on a resin sheet or film, and for example, a gravure printing method, silk screen printing, etc. Use a printing method such as printing method.

  For example, it can be configured by forming a desired printed picture made up of characters, figures, pictures, symbols, etc.

In the above, various ink compositions include, for example, as a vehicle constituting the ink composition, for example, polyolefin resins such as polyethylene resins and chlorinated polypropylene resins, poly (meth) acrylic resins, polyvinyl chloride Resin, polyvinyl acetate resin, vinyl chloride-vinyl acetate copolymer, polystyrene resin, styrene-butadiene copolymer, vinylidene fluoride resin, polyvinyl alcohol resin, polyvinyl acetal resin, Polyvinyl butyral resin, polybutadiene resin, polyester resin, polyamide resin, alkyd resin, epoxy resin, unsaturated polyester resin, thermosetting poly (meth) acrylic resin, melamine resin, urea Resin, polyurethane resin, phenol
Rubber resins such as cellulose resins, xylene resins, maleic acid resins, nitrocellulose, ethylcellulose, acetylbutylcellulose, ethyloxyethylcellulose, etc., chlorinated rubber, cyclized rubber, etc. Further, natural resins such as petroleum resins, rosin and casein, fats and oils such as linseed oil and soybean oil, and other resins can be used.

  Hereinafter, the present invention will be described in more detail with reference to specific examples, but the present invention is not limited thereto.

<Example 1>
Polyethylene resin layer 1 / adhesive resin layer 2 / nylon (polyamide) 5 / ethylene-vinyl alcohol copolymer resin layer (EVOH) 3 / nylon (polyamide) resin layer 5 / adhesive layer 13 / polyethylene resin shown in FIG. 5% by weight of “2- (3-tert-butyl-5-methyl-2-hydroxyphenyl) -5-chlorobenzotriazole” (tinuvin 326) as an ultraviolet absorber is applied to the polyethylene resin layer 1 in the upper direction in the configuration of the layer 1 Then, an organic transparent yellow pigment was added in an amount of 2% by weight to prepare a laminated material having a structure as shown in FIG.

  The produced laminated material having a total thickness of 250 μm was measured with a spectrophotometer (manufactured by Shimadzu Corporation). The results are shown in Table 1.

  Next, the produced laminated material was vacuum-formed using a vacuum forming machine, and a tray-like container 102 as shown in FIG. 9 was produced. Then, 100 ppm of vitamin B2 ampoule 101 (polyethylene 25 ml container) and oxygen scavenger [C-25] 104 (manufactured by Toppan Printing Co., Ltd.) were filled in the tray-shaped container 102 thus prepared.

  Also, alumina-deposited polyethylene terephthalate film 9 (12 μm) / UV cut ink 23 + transparent yellow ink coat 22 / adhesive layer 13 / stretched nylon film layer 11 (15 μm) / LLDPE resin layer 12 (30 μm) as shown in FIG. The lid member 70 having the configuration was produced.

  Then, the opening of the tray-like container 102 filled with the ampoule 101 and the oxygen scavenger [C-25] 104 was sealed by heat sealing using the lid member 70 using a tray heat sealing machine.

<Example 2>
The structure of polypropylene resin layer 4 / adhesive resin layer 2 / ethylene-vinyl alcohol copolymer resin layer (EVOH) 3 / adhesive layer 13 / polypropylene resin layer 4 shown in FIG. The inner surface is coated with UV absorber of 2, 2 ', 4, 4' tetrahydroxybenzophenone and varnish with chlorinated polypropylene resin as binder, 1.5g / m ² (dry coating amount). A coat layer was formed. Further, a transparent yellow ink layer is formed by coating the surface of the formed UV absorber coating layer with a transparent yellow ink using a chlorinated polypropylene resin as a binder resin with a coating machine of 1.5 g / m ² (dry coating amount), A laminated material having a total thickness of 150 μm configured as shown in FIG. 6 was produced.

Then, the produced laminate material having a total thickness of 150 μm was used as a spectrophotometer (manufactured by Shimadzu Corporation).
). The results are shown in Table 2.

  Next, the produced laminated material having a total thickness of 150 μm was vacuum-formed using a vacuum forming machine, and a tray-like container 91 as shown in FIG. 10 was produced. The prepared tray-like container 91 was filled with 1000 ppm of vitamin B2 prefilled syringe 92 (2 ml) and oxygen scavenger [C-25] 84 (manufactured by Toppan Printing Co., Ltd.).

  Further, a cover material having a structure of alumina vapor-deposited polyethylene terephthalate film 9 (12 μm) / UV cut ink coat layer 23 + transparent yellow ink coat layer 22 / adhesive layer 13 / LLDPED resin layer 12 (25 μm) as shown in FIG. 80 was produced.

  Then, the lid 80 is heat sealed at the opening of the tray-like container 91 filled with the prefilled syringe 92 (2 ml) and the oxygen scavenger [C-25] 104 using a heat seal machine for trays. Sealed.

<Comparative example 1>
In Example 1, the tray-like container 102 and the lid material 70 shown in FIG. 9 are produced in the same manner as in Example 1 except that the ultraviolet absorbent and the organic transparent yellow pigment are not added to the polyethylene resin layer 1 in the upward direction. did. And the opening part of the tray-like container 1021 with which the ampoule 101 and the oxygen absorber [C-25] 104 were filled was sealed with the heat sealing | sealing material 70 with the heat seal machine for trays.

<Comparative example 2>
In Example 2, a tray-like container 91 and a lid member 80 were produced in the same manner as in Example 2 except that the ultraviolet absorber coating layer and the transparent yellow ink layer were not formed. Then, the lid 80 is heat sealed at the opening of the tray-like container 91 filled with the prefilled syringe 92 (2 ml) and the oxygen scavenger [C-25] 104 using a heat seal machine for trays. Sealed.

<Evaluation>
Fluorescent lamps having a tray-like container in which the openings of Examples 1 and 2 and Comparative Examples 1 and 2 were sealed by heat sealing were set to 12,000 lx · hr in an environment of 25 ° C. and 65% RH. The light was irradiated. And after irradiation, the residual amount of vitamin B2 was measured by liquid chromatography. The results are shown in Table 3.

<Evaluation results>
As shown in Table 3, the laminated material and the package of the present invention cut light in the visible light (500 nm or less) region with a short wavelength from the ultraviolet region. For this reason, it has been confirmed that sufficient storage stability can be obtained even for components that are easily decomposed by short-wavelength visible light such as vitamin B2, which cannot be preserved with ordinary UV-cut packaging materials. . Further, the tray-like container after the measurement could be crushed and easily discarded.

  The laminated material and package of the present invention are excellent inventions that can be used not only for packaging materials for various foods and pharmaceuticals and medical supplies, but also for the precision machinery field or the industrial material processing field.

It is explanatory drawing which shows the cross section of one Example of the laminated material of this invention. It is explanatory drawing which shows the cross section of other one Example of the laminated material of this invention. It is explanatory drawing which shows the cross section of one Example of the laminated material of this invention. It is explanatory drawing which shows the cross section of one Example of the laminated material of this invention. It is explanatory drawing which shows the cross section of one Example of the laminated material of this invention. It is explanatory drawing which shows the cross section of one Example of the laminated material of this invention. It is explanatory drawing which shows the cross section of one Example of the cover material used for the package body of this invention. It is explanatory drawing which shows the cross section of other one Example of the cover material used for the package body of this invention. It is explanatory drawing explaining one Example of the package of this invention. It is explanatory drawing explaining one Example of the package of this invention.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 ... Polyethylene resin layer 2 ... Adhesive resin layer 3 ... Ethylene-vinyl alcohol copolymer resin layer (EVOH)
DESCRIPTION OF SYMBOLS 4 ... Polypropylene resin layer 5 ... Nylon (polyamide) resin layer 6 ... Ultraviolet absorber kneaded polyethylene resin layer 7 ... Polyethylene terephthalate resin layer 8 ... Alumina vapor deposition layer 9 ... Alumina vapor deposition polyethylene terephthalate resin layer 11 ... Stretched nylon layer long hole 12 ... Linear low density polyethylene resin 13 ... Adhesive layer 21 ... UV absorber coat layer 22 ... Transparent yellow ink coat layer 23 ... UV cut ink coat layer 24 ... UV absorption coat layer 10 ... Laminated material 20 ... Laminated material 30 ... Laminated Material 40 ... Laminated material 50 ... Laminated material 60 ... Laminated material 70 ... Lid material 80 ... Lid material 84 ... Deoxygenating agent 91 ... Tray-shaped container 92 ... Prefilled shilling 101 ... Ampoule

Claims (6)

A laminated material in which at least a layer comprising polyolefin and an ethylene-vinyl alcohol copolymer is laminated,
The laminated material has a total light transmittance at a wavelength of 380 nm of 1% or less, a total light transmittance at a wavelength of 500 nm of 5% or less, and a total light transmittance at a wavelength of 600 nm of 70% or more. Laminated material.   An ultraviolet absorber or yellow pigment is kneaded in a part or all of the laminated material, or / and an ink in which the ultraviolet absorber or yellow pigment is dispersed is applied. 2. The laminated material according to claim 1.   3. The amount or thickness of the ultraviolet absorber or yellow pigment to be kneaded or / and applied is selected as appropriate depending on whether the outside is large or the inside is large. Laminated material.   The laminated material according to any one of claims 1 to 3, wherein the laminated material has a total thickness of 120 µm or more and 250 µm or less.   A package comprising the laminated material according to any one of claims 1 to 4 formed into a bag shape.   A package comprising the laminate material according to any one of claims 1 to 4 formed into a container shape.

Images