JP2008156246A - Toothpaste composition - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a toothpaste composition rich in an actual cleaning feeling (impartment of a refreshing feeling to tooth surfaces) after tooth brushing and excellent usability with little irritation and stickiness. <P>SOLUTION: The toothpaste composition comprises (a) a dialkyl sulfosuccinic ester salt, (b) a polyoxyethylene alkyl ether and (c) a polyoxyethylene hardened castor oil in 1.0-5.0 mass ratio of [(b)+(c)]/(a). (b) The polyoxyethylene alkyl ether has a 12-18C alkyl group and 3-8 average molar addition number of ethylene oxides. (c) The polyoxyethylene hardened castor oil has 10-30 average molar addition number of the ethylene oxides. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a toothpaste composition which is rich in the effect of imparting a cleaning feeling after tooth brushing (a refreshing feeling on the tooth surface) and has little irritation and stickiness.

  It is generally accepted that the first cause of dental caries and periodontal disease, which are the two major oral diseases, is the accumulation of plaque. Dentifrices containing various active ingredients are widely used as a means of daily plaque control. in use. Furthermore, in order to continue to practice plaque control, the user's willingness to control plaque can be achieved by having a clean feeling that the plaque has been removed from the tooth surface after brushing (a refreshing feeling on the tooth surface). It is considered necessary for improvement.

  Up to now, as a technique for imparting a cleaning feeling after brushing teeth, a composition for oral cavity in which beeswax and / or honey beeswax and borax are used in combination and a nonionic surfactant is blended (Patent Document 1; Japanese Patent Application Laid-Open No. 2004-18521). Publication), oral composition using polyoxyethylene alkyl ether and polyethylene glycol in combination with glucanase (Patent Document 2; JP-A-2004-262882), hydroxyethylcellulose dimethyl diallyl ammonium salt, sodium lauryl sulfate and polyoxyethylene alkyl ether A toothpaste composition (Patent Document 3; Japanese Patent Application Laid-Open No. 2006-199680) containing polyoxyethylene hydrogenated castor oil and sodium alginate is known.

  However, all of these techniques are techniques for imparting a smooth feeling by retaining the polymer compound on the tooth surface. However, in such a technique, the polymer compound remains on the tooth surface, so that some users For this, this was sometimes felt uncomfortable. Therefore, it has been desired to develop an excellent cleaning feeling imparting technique that does not depend on polymer compound adsorption.

JP 2004-18521 A JP 2004-262882 A JP 2006-199680 A Japanese Patent Laid-Open No. 10-17443

  The present invention has been made in view of the above circumstances, and provides a toothpaste composition which is rich in cleaning feeling after tooth brushing (giving a refreshing feeling on the tooth surface) and has little irritation and stickiness and excellent usability. Objective.

  As a result of intensive studies to achieve the above object, the present inventors have found that (a) a dialkylsulfosuccinic acid ester salt and (b) an alkyl group having 12 to 18 carbon atoms and an average added mole number of ethylene oxide of 3 to 8 Of polyoxyethylene alkyl ether, (c) polyoxyethylene hydrogenated castor oil having an average addition mole number of ethylene oxide of 10 to 30, and the blending ratio of ((b) + (c)) / (a) By setting the ratio to 1.0 to 5.0, the cleaning feeling after brushing is rich, and there is little irritation and stickiness, and the above-mentioned conventional polymer compound is retained on the tooth surface. A toothpaste that gives a feeling that dirt is completely removed from the tooth surface and gives excellent usability without the user feeling a sense of incongruity like technology. Was found that growth was obtained, the present invention has been accomplished.

  In addition, dialkyl sulfosuccinic acid esters are blended in dentifrice compositions as sulfosuccinic acid surfactants, and sulfosuccinic surfactants such as sulfosuccinic acid monoesters are known to exhibit excellent stain formation inhibitory effects. In the present invention, (b) polyoxyethylene alkyl ether and (c) polyoxyethylene hydrogenated castor oil are added to (a) dialkyl sulfosuccinate ester salt. By combining and blending at a specific ratio, it is possible to give the user a cleaning feeling (smoothness of the tooth surface) that the dirt has been removed from the tooth surface after brushing by the strong penetrating detergency unique to dialkylsulfosuccinate salts. Excellent action that can be used and has good irritation with little irritation and stickiness It has been found that the result is exhibited.

  Accordingly, the present invention provides (a) a dialkylsulfosuccinic acid ester salt, (b) a polyoxyethylene alkyl ether having an alkyl group having 12 to 18 carbon atoms and an average added mole number of ethylene oxide of 3 to 8, It contains polyoxyethylene hydrogenated castor oil having an average addition mole number of ethylene oxide of 10 to 30, and the mass ratio of ((b) + (c)) / (a) is 1.0 to 5.0. A toothpaste composition is provided.

  ADVANTAGE OF THE INVENTION According to this invention, the toothpaste composition of the outstanding usability which is rich in the cleaning feeling after tooth brushing (giving the refreshing feeling of a tooth surface), and there is little irritation | stimulation and stickiness feeling can be provided.

  Hereinafter, the toothpaste composition of the present invention will be described in more detail with respect to the present invention. (A) Dialkyl sulfosuccinate ester salt, (b) Alkyl group having 12 to 18 carbon atoms, and average added mole number of ethylene oxide 3 to 8 polyoxyethylene alkyl ether, (c) polyoxyethylene hydrogenated castor oil having an average addition mole number of ethylene oxide of 10 to 30.

  As the (a) dialkylsulfosuccinic acid ester salt to be blended in the present invention, an alkali metal salt of a dialkylsulfosuccinic acid ester having an alkyl chain generally having 6 to 10 carbon atoms, particularly 8 is preferable, particularly a sodium salt, and dioctyl sulfosuccinate. Sodium can be preferably used.

  Commercially available products can be used as such dialkylsulfosuccinates. Examples of commercially available products include dioctyl sodium sulfosuccinate (NIKKOL OTP-75 from Nikko Chemicals Co., Ltd.), dioctyl sodium sulfosuccinate (Ripal 870P from Lion Corp.). ) And the like.

  (A) The compounding quantity of the dialkyl sulfosuccinic acid ester salt is 0.05 to 2.0% (mass%, the same applies hereinafter) in the composition, preferably 0.1 to 1.0%. If it is less than 0.05%, it is difficult to give a cleaning feeling. If it exceeds 2.0%, (b) component polyoxyethylene alkyl ether and (c) polyoxyethylene hydrogenated castor oil are used in combination. However, it may be difficult to reduce irritation within the range of good usability.

  Next, polyoxyethylene alkyl ether is used in which the average number of moles of ethylene oxide added is 3 to 8 moles, preferably 3 to 5 moles, from the viewpoint of stimulus relaxation and usability. When the added mole number of ethylene oxide is less than 3, foaming is inferior, and satisfactory cleaning feeling cannot be obtained, and when it exceeds 8, the stimulus relaxation action cannot be obtained.

  In addition, the carbon chain of the alkyl group of the polyoxyethylene alkyl ether has 12 to 18 carbon atoms, preferably 16 to 18 carbon atoms, from the viewpoints of stimulus relaxation and feeling of use. Those having a carbon number of less than 12 are inferior in the persistence of bubbles, and those having a carbon number of more than 18 are not able to provide a stimulus mitigating action.

  Examples of such polyoxyethylene alkyl ethers include polyoxyethylene (3) cetyl ether, polyoxyethylene (5) cetyl ether, polyoxyethylene (7) cetyl ether, polyoxyethylene (3) stearyl ether, polyoxyethylene Examples include ethylene (4) stearyl ether, polyoxyethylene (5) stearyl ether, polyoxyethylene (6) stearyl ether, polyoxyethylene (7) stearyl ether, polyoxyethylene (8) stearyl ether, and the like.

  Among these polyoxyethylene alkyl ethers, those having an average number of moles of added ethylene oxide of 5 and a carbon chain length of the alkyl group of 16 to 18 are particularly preferably used from the viewpoint of irritation mitigation and usability. Specifically, polyoxyethylene (5) stearyl ether and polyoxyethylene (5) cetyl ether are preferred.

  A commercial item can be used for such polyoxyethylene alkyl ether. As commercial products, for example, in the product of Nippon Emulsion Co., the alkyl ether is cetyl ether (polyoxyethylene cetyl ether), Emarex 103, Emarex 105, Emarex 107, and alkyl ether is stearyl ether ( Examples of the polyoxyethylene stearyl ether) include EMALEX 603, EMALEX 605, EMALEX 606, and EMALEX 608.

  (B) The blending amount of polyoxyethylene alkyl ether is 0.1 to 5%, particularly 0.5 to 3%, particularly 0.8 to 2% of the whole toothpaste composition from the viewpoint of irritation mitigation and usability. Is preferred. If the blending amount is less than 0.1%, a sufficient irritation mitigating effect may not be obtained, and if it exceeds 5%, stickiness or the like may occur, and the feeling of use of the toothpaste composition may be reduced.

  Moreover, the polyoxyethylene hydrogenated castor oil uses the thing whose average added mole number of ethylene oxide is 10-30, Preferably 20 from the point of irritation | stimulation relaxation and a usability | use_condition. When the average number of added moles of ethylene oxide is less than 10, sufficient foaming cannot be obtained, and when it exceeds 30, the stimulus relaxation action cannot be obtained.

  As such polyoxyethylene hydrogenated castor oil, for example, HCO-10, HCO-20, HCO-30 from Nikko Chemicals Co., Ltd., HC-10, HC-20, HC-30 from Nihon Emulsion Co., Ltd., Aoki Yushi Kogyo Co., Ltd. BLAUNON RCW-20 (polyoxyethylene 20 mol) of a corporation | Co., Ltd. etc. is mentioned.

  (C) The blending amount of the polyoxyethylene hydrogenated castor oil is 0.1 to 5%, preferably 0.5 to 3%, particularly preferably 0. 8 to 2%. If the blending amount is less than 0.1%, a sufficient irritation mitigating effect cannot be obtained, and if it exceeds 5%, stickiness or the like occurs and the feeling of use of the dentifrice is poor.

  In the present invention, (a) a dialkylsulfosuccinic acid ester salt, (b) a polyoxyethylene alkyl ether having an alkyl group having 12 to 18 carbon atoms and an average addition mole number of ethylene oxide of 3 to 8, (c) ethylene oxide The polyoxyethylene hydrogenated castor oil having an average added mole number of 10 to 30 has a mass ratio of ((b) + (c)) / (a) of 1.0 to 5.0, preferably 3.0 to 5. When the mass ratio is less than 1.0, a sufficient cleaning feeling cannot be obtained. When the mass ratio exceeds 5.0, stickiness occurs and the feeling of use of the dentifrice is inferior.

  The toothpaste composition of the present invention can contain other additives as optional components in addition to the above-mentioned components (a) to (c), which are essential components, such as abrasives, wetting agents, binders, and surface active agents. Agents, fragrances, sweeteners, preservatives, various active ingredients, colorants and the like can be blended, and these ingredients can be mixed with water.

  As the abrasive, anhydrous silicic acid, amorphous anhydrous silicic acid, dentifrice calcium hydrogen phosphate, aluminum hydroxide, and the like can be blended, as well as calcium pyrophosphate, calcium carbonate, alumina, magnesium carbonate, tertiary magnesium phosphate, Inorganic abrasives such as insoluble sodium metaphosphate, insoluble potassium metaphosphate, and titanium oxide, and organic abrasives such as polymethyl methacrylate and crystalline cellulose can be blended. 5-60% of the whole composition is suitable for the compounding quantity of an abrasive | polishing agent, Preferably it is 10-50%.

  Examples of the wetting agent include sorbit, glycerin, propylene glycol, xylit, malt, lactit and the like, and sorbit and xylit are particularly preferable. The blending amount of these wetting agents is preferably 10 to 60%, particularly 20 to 50% of the entire composition.

  As binder, cellulose derivatives such as carrageenan, sodium carboxymethyl cellulose, methyl cellulose, hydroxyethyl cellulose, gums such as xanthan gum, tragacanth gum, karaya gum, arabic gum, polyvinyl alcohol, crosslinked sodium polyacrylate, uncrosslinked sodium polyacrylate, etc. And organic binders such as carboxyvinyl polymer and polyvinylpyrrolidone, and inorganic binders such as silica gel, aluminum silica gel, bee gum, and laponite. The compounding amount of the binder is preferably 0.1 to 5%, more preferably 0.5 to 3%.

  As surfactants other than (a) dialkylsulfosuccinic acid ester salts, (b) polyoxyethylene alkyl ethers and (c) polyoxyethylene hydrogenated castor oil, anionic surfactants, cations Anionic surfactant, nonionic surfactant, and amphoteric surfactant can be blended. Examples of anionic surfactants include sodium alkyl sulfates such as sodium lauryl sulfate and sodium myristyl sulfate, sodium N-acyl sarcosinate such as sodium N-lauroyl sarcosinate, sodium N-myristoyl sarcosinate, sodium dodecylbenzenesulfonate, hydrogen Added coconut fatty acid monoglyceride sodium monosulfate, sodium lauryl sulfoacetate, N-acyl glutamate such as sodium N-palmitoyl glutamate, N-methyl-N-acyl taurine sodium, N-methyl-N-acylalanine sodium, α-olefin sulfone Anionic activators such as sodium acid can be used. Nonionic surfactants include sugar alcohol fatty acid esters such as sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, sucrose fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid ester, polyoxyethylene glycerin fatty acid ester, polyethylene glycol fatty acid. Examples thereof include polyhydric alcohol fatty acid esters such as esters, polyoxyethylene polyoxypropylene copolymers, ether type surfactants such as polyoxyethylene alkylphenyl ether, and fatty acid alkanolamides such as lauric acid diethanolamide. Examples of the cationic surfactant include alkylammonium and alkylbenzylammonium salts. Examples of amphoteric surfactants include betaine acetate, imidazolinium betaine, and lecithin.

  The amount of the surfactant as an optional component is preferably 0 to 2%, more preferably 0.1 to 1.5%.

  As a sweetener, saccharin sodium, stevioside, neohesperidyl dihydrochalcone, glycyrrhizin, perilartine, aspartame, xylitol and the like can be blended.

Perfumes include peppermint oil, spearmint oil, anise oil, eucalyptus oil, winter green oil, cassia oil, clove oil, thyme oil, sage oil, lemon oil, orange oil, peppermint oil, cardamom oil, coriander oil, mandarin oil, Lime oil, lavender oil, rosemary oil, laurel oil, camomil oil, caraway oil, marjoram oil, bay oil, lemongrass oil, origanum oil, pine needle oil, neroli oil, rose oil, jasmine oil, grapefruit oil, sweetie Natural fragrances such as oil, bran oil, Iris concrete, absolute peppermint, absolute rose, orange flower, and processing of these natural fragrances (front reservoir cut, rear reservoir cut, fractional distillation, liquid-liquid extraction, essence, Powdered fragrance etc.) and menthol Carvone, anethole, cineol, methyl salicylate, synamic aldehyde, eugenol, 3-l-mentoxypropane-1,2-diol, thymol, linalool, linalyl acetate, limonene, menthone, menthyl acetate, N-substituted paramentan 3-carboxamide, pinene, octylaldehyde, citral, pulegone, carbyl acetate, anisaldehyde, ethyl acetate, ethyl butyrate, allyl cyclohexane propionate, methyl anthranilate, ethyl methyl phenyl glycidate, vanillin, undecalactone, Hexanal, butanol, isoamyl alcohol, hexenol, dimethyl sulfide, cycloten, furfural, trimethylpyrazine, ethyl lactate, ethyl Oral compositions such as single flavors such as thioacetate, and other flavors such as strawberry flavor, apple flavor, banana flavor, pineapple flavor, grape flavor, mango flavor, butter flavor, milk flavor, fruit mix flavor, tropical fruit flavor, etc. It can be used in combination with known perfume materials used in the above.
Moreover, although a compounding quantity is not specifically limited, As a fragrance | flavor for fragrance | flavor using the said fragrance | flavor raw material, it is preferable to use 0.1 to 2.0% in a formulation composition.

  As colorants, Red No. 2, Red No. 3, Red No. 225, Red No. 226, Yellow No. 4, Yellow No. 5, Yellow No. 205, Blue No. 1, Blue No. 2, Blue No. 201, Blue No. 204, Green No. 3 No., mica titanium, titanium oxide and the like.

  Various active ingredients include sodium fluoride, potassium fluoride, stannous fluoride, strontium fluoride, sodium monofluorophosphate and other water-soluble phosphate compounds such as orthophosphoric acid potassium salt and sodium salt. , Glucanases such as dextranase and mutanase, allantoin chlorohydroxyaluminum, hinokitiol, ascorbic acid, lysozyme chloride, glycyrrhizic acid and its salts, sodium chloride, tranexamic acid, epsilon aminocaproic acid, dl-tocophenol acetate, α-bisabolol, isopropyl Copper compounds such as methylphenol, chlorohexidine salts, cetylpyridinium chloride, azulene, glycyrrhetinic acid, copper chlorophyllin sodium, copper gluconate, aluminum lactate, strontium chloride, potassium nitrate , Berberine, hydroxamic acid and its derivatives, sodium tripolyphosphate, zeolite, amylase, methoxyethylene, maleic anhydride copolymer, polyvinylpyrrolidone, epidihydrocholesterin, benzethonium chloride, dihydrocholesterol, trichlorocarbanilide, zinc citrate , Extract of Toki soft extract, duckweed extract, clove, rosemary, gourd, safflower and the like. In addition, the said active ingredient can be mix | blended in an effective amount in the range which does not prevent the effect of this invention.

  The material of the container for housing the toothpaste composition of the present invention is not particularly limited, and a container usually used for a toothpaste composition can be used. Specifically, an aluminum tube, a laminated tube obtained by laminating both surfaces of aluminum with plastic, a plastic tube, a container such as a bottle-shaped container or an aerosol container can be used.

  EXAMPLES Hereinafter, although an Example and a comparative example are shown and this invention is demonstrated concretely, this invention is not restrict | limited to the following Example. In the following examples, the blending amount is mass%.

In addition, the component used in the following example is as follows.
(A) Dioctyl sodium sulfosuccinate; NIKKOL OTP-75 manufactured by Nikko Chemicals Co., Ltd.
(B) Polyoxyethylene stearyl ether (average added mole number of ethylene oxide 5); Emalex 605 manufactured by Nippon Emulsion Co., Ltd.
(C) Polyoxyethylene hydrogenated castor oil (average added mole number of ethylene oxide 20); Emulex HC-20 manufactured by Nippon Emulsion Co., Ltd.

[Examples 1-6, Comparative Examples 1-6]
The toothpaste compositions having the compositions shown in Tables 1 and 2 were prepared by the following method and evaluated as follows.

Preparation of test toothpaste composition:
To prepare the dentifrice composition, dissolve water-soluble substances such as active ingredients, flavoring agents, preservatives, wetting agents (other than propylene glycol) and colorants in purified water, and then separately disperse the binder in propylene glycol. The solution was added and stirred. Thereafter, a perfume, an abrasive, heat-dissolved polyoxyethylene alkyl ether, polyoxyethylene hydrogenated castor oil, dialkyl sulfosuccinate ester salt, and other optional surfactants were added in order, and further stirred under reduced pressure (40 mmHg). A toothpaste composition was obtained. A unimixer (FM-SR-25, POWEX CORPORATION) was used for the production.

[Evaluation method]
About the toothpaste composition shown in Table 1, 10 subjects took 1 g of the toothpaste composition in a toothbrush (Lion Corporation, PC CLINICA Brush Brush), brushed for 3 minutes, and the cleaning feeling immediately after brushing. An average value was obtained by performing a sensory test based on the following criteria for the degree of irritation during tooth brushing, the degree of irritation during brushing, and the feeling of stickiness during brushing.

A feeling of cleaning after brushing teeth (a refreshing feeling on the tooth surface):
(Score)
3 points: Compared to Comparative Example 6, the tooth surface after brushing is more refreshing 2 points: Compared to Comparative Example 6, the tooth surface after brushing is slightly higher 1 point: Compared to Comparative Example 6 Compared with the degree of refreshing of the tooth surface after brushing 0 points: Compared to Comparative Example 6, the degree of tooth surface after brushing is less (evaluation criteria for the feeling of the tooth surface after brushing)
◎ Average refreshing point of tooth surface after brushing 2.5 to 3.0 points ○ Average refreshing point of tooth surface after brushing 2.0 to less than 2.5 points △ Refreshing feeling of tooth surface after brushing Average point 1.0 point to less than 2.0 point × Refreshing average point of tooth surface after brushing Less than 1.0 point

The degree of irritation during brushing:
(Score)
3 points: the degree of irritation during brushing is low compared to Comparative Example 6 2 points: the degree of irritation during toothbrushing is comparable to Comparative Example 6 1 point: irritation during toothbrushing compared to Comparative Example 6 Slightly high 0 point: Compared to Comparative Example 6, the degree of stimulation during brushing is high (evaluation level of stimulation during brushing)
◎ Average score of the degree of irritation during tooth brushing 2.5 to 3.0 points ○ Average score of the degree of irritation during tooth brushing 2.0 to less than 2.5 points △ Average score of the degree of irritation during tooth brushing 1 .0 point to less than 2.0 point × average point of degree of irritation during tooth brushing less than 1.0 point

Feeling of use while brushing teeth (stickiness):
(Score)
3 points: less sticky feeling during tooth brushing than Comparative Example 6 2 points: less sticky feeling during tooth brushing than Comparative Example 6 1 point: less sticky feeling during tooth brushing than Comparative Example 6 Slightly high 0 point: Compared with Comparative Example 6, the feeling of stickiness during brushing is high (evaluation criteria for degree of irritation during brushing)
◎ Average point of stickiness during tooth brushing 2.5 to 3.0 points ○ Average point of stickiness during tooth brushing 2.0 to less than 2.5 points △ Average point of stickiness during tooth brushing 1.0 point ~ Less than 2.0 points × Average point of stickiness during tooth brushing Less than 1.0 points

  The results are shown in Tables 1 and 2. In addition, all the numerical values showing the compounding quantity in a table | surface are the mass%.

  Next, a toothpaste composition having the following composition was prepared by a conventional method and evaluated in the same manner as in Example 1. As a result, excellent cleaning feeling was obtained, and the problem of irritation and stickiness was I was not able to admit.

[Example 7] Toothpaste, propylene glycol 3%
Sodium alginate 0.6
Xanthan gum 0.7
Sorbit liquid (70%) 45
Silicic anhydride 20
Titanium oxide 0.4
Sodium fluoride 0.21
Saccharin sodium 0.15
Sodium lauryl sulfate 0.8
(A) Dioctyl sodium sulfosuccinate 0.4
(B) Polyoxyethylene (5) stearyl ether 0.7
(C) Polyoxyethylene (20) hydrogenated castor oil 0.7
Fragrance 1.2
100% pure water balance <br/>
((B) + (c)) / (a) = 3.5

[Example 8] Toothpaste, propylene glycol 3%
Sodium alginate 0.6
Xanthan gum 0.7
Sorbit liquid (70%) 45
Silicic anhydride 20
Titanium oxide 0.4
Sodium fluoride 0.21
Saccharin sodium 0.15
Dextranase 0.16
DL-alanine 0.3
Sodium lauryl sulfate 0.8
(A) Dioctyl sodium sulfosuccinate 0.5
(B) Polyoxyethylene (5) stearyl ether 1.0
(C) Polyoxyethylene (20) hydrogenated castor oil 1.0
Fragrance 1.2
100% pure water balance <br/>
((B) + (c)) / (a) = 4.0

[Example 9] Toothpaste, propylene glycol 3%
Sodium alginate 0.6
Xanthan gum 0.7
Sorbit liquid (70%) 30
Silica anhydride 2.0
Calcium carbonate 35
Sodium monofluorophosphate 0.73
Saccharin sodium 0.15
Sodium lauryl sulfate 0.8
(A) Dioctyl sodium sulfosuccinate 0.3
(B) Polyoxyethylene (5) stearyl ether 0.5
(C) Polyoxyethylene (20) hydrogenated castor oil 0.5
Fragrance 1.2
100% pure water balance <br/>
((B) + (c)) / (a) = 3.3

[Example 10] Toothpaste, propylene glycol 3%
Sodium alginate 0.6
Xanthan gum 0.7
Sorbit liquid (70%) 30
Silica anhydride 2.0
Calcium phosphate 40
Sodium monofluorophosphate 0.73
Saccharin sodium 0.15
Sodium lauryl sulfate 0.8
(A) Dioctyl sodium sulfosuccinate 0.5
(B) Polyoxyethylene (5) stearyl ether 1.0
(C) Polyoxyethylene (20) hydrogenated castor oil 1.0
Fragrance 1.2
100% pure water balance <br/>
((B) + (c)) / (a) = 4.0

Claims (1)

  (A) dialkylsulfosuccinic acid ester salt, (b) polyoxyethylene alkyl ether having 12 to 18 carbon atoms in the alkyl group and an average addition mole number of ethylene oxide of 3 to 8, (c) average addition mole of ethylene oxide A toothpaste composition comprising polyoxyethylene hydrogenated castor oil having a number of 10 to 30 and a mass ratio of ((b) + (c)) / (a) of 1.0 to 5.0 object.