JP2008127335A - Method for preventing diseases of plants - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a method for preventing various crops from pathogenic microbes, characterized by applying a composition containing (RS)-N-[2-(1,3-dimethylbutyl)thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide (general name: penthiopyrad) as an active ingredient to plant seeds, and to provide a method for preventing present actualized resistant microbes. <P>SOLUTION: This method for preventing the pathogenic microbes is characterized by contacting a composition containing penthiopyrad with plant seeds. The method for preventing the pathogenic microbes exhibits an effect for preventing various crops from pathogenic microbes and also an effect for preventing the various crops from present actualized resistant microbes. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to (RS) -N- [2- (1,3-dimethylbutyl) thiophen-3-yl] -1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide (generic name penthiopyrad). The present invention relates to a method for preventing plant diseases by applying a composition containing an active ingredient to plant seeds.

  Penthiopyrad is a fungicidal compound and is applied by seed disinfection, foliage spraying, and other methods such as rice blast (Piculararia oryzae), sesame leaf blight (Rhizoctonia solani), idiotic buri ell , Wheat powdery mildew (Erysiphe graminis), leafy leaf disease (Pyrenophora graminea), snow rot (Typhula sp,), naked smut (Ustylago tritici), grape powdery mildew (Uncinula nector) Podosphaera leukotricha, cucumber powdery mildew (Sphaerotheca furiginea) Although it is described in JP-A-9-235282, it shows that disease is prevented by an application method such as spraying treatment, smearing treatment, dipping treatment or powdering treatment on plant seeds. No description has been made.

In addition, as conventional agents for preventing plant diseases by applying to plant seeds, there are benomyl agents, thiophanate methyl agents, prochloraz agents, pephrazoate agents, etc., which are spraying treatment, smearing treatment, dipping treatment or powdering to seeds. It is known to be effective in clothing processing. However, among these agents, it has been reported that benomyl agents and thiophanate methyl agents have reduced control effects on some pathogens such as rice blast fungus and sesame leaf blight fungus. Prochloraz is applicable to rice blast disease, sesame leaf blight, stupid seedling disease, tulip bulb rot, and rakkyo dry rot in seed treatment, but there is no report that other diseases can be prevented. Similarly, although the pefazoate agent is applied to rice blast disease, sesame leaf blight, tobacco seedling disease, wheat red snow rot, and tulip bulb rot in seed treatment, there is no report that other diseases can be prevented.
Japanese Patent Laid-Open No. 9-235282

  An object of the present invention is to provide a method for preventing a disease of a new plant, which has a plurality of disease spectrums against pathogenic bacteria of various plants, and which is also effective against resistant bacteria that are currently manifested. is there.

  As a result of intensive studies in view of such circumstances, the present inventors have found that a composition containing penthiopyrad as an active ingredient exhibits a high preventive effect on a plurality of diseases at a low dose, and is also stable against the resistant bacteria. As a result, the present inventors have found a method for indicating the above.

  That is, the present invention provides a new method for preventing plant diseases characterized by containing penthiopyrad as an active ingredient.

  The preventive method using the composition containing penthiopyrad of the present invention as an active ingredient exhibits a high preventive effect against diseases occurring in plants, and also exhibits a stable preventive effect against resistant bacteria against existing compositions.

  The spraying treatment, smearing treatment, dipping treatment or powdering treatment on the plant seed of the composition containing the penthiopyrad of the present invention as an active ingredient can prevent diseases occurring in the plant.

  Specific examples of diseases that can be controlled include rice blast (Piculararia oryzae), sesame leaf blight (Cochliobolus miyabeanus), idiot seedling (Gibberella fujikurai), and barley leaf (Pyrenophora). smut (Ustilago nuda, Ustilago tritici, Ustilago nigra, Ustilago avenae), fishy smell smut (Tilletia caries, Tilletia pancicii), Ken smut (Ustilago hordei, Ustilago kolleli), scald (Rhynchosporium secalis), leaf blight (Septoria tritici), Blight disease (Leptosphaeria nodorum), Scarlet snow rot (Microdochium nivale), Red mold disease (Fusarium graminumum, Fusarium culumumum, Fusarium acumenum, Microdum) Spot disease (Cephalosporium gramineum), reticular leaf disease (Dreschlera teres), corn smut (Ustilago mydis), legume seedling blight (Rhizoctionia solani), mycorrhizal disease (Sclerotinia scleroto) Izu purpura (Cercospora kikuchii), Rhizoctonia solani, sugar beet root rot (Rhizotconia solani), rape rot (Leptosperia maculans) Examples include, but are not limited to, radish, watermelon, eggplant, green pepper, spinach, and various vegetable seedling blights (Rhizotonia solani).

  The plant seeds to which the present invention can be applied mean those that store nutrients for germination of young plants and are used for agricultural propagation. For example, seeds such as corn, soybean, cotton, rice, sugar beet, wheat, barley, sunflower, tomato, cucumber, eggplant, spinach, sweet pea, pumpkin, sugar cane, tobacco, pepper and rape, taro, potato, sweet potato, konjac Seed bulbs, edible lily, bulbs such as tulips and seed balls such as sea urchins. These plant seeds may be transformed. A transformed plant refers to a plant that has been created by artificially manipulating genes and the like and does not exist in nature. Examples thereof include corn, cotton, potato and the like that have been provided with the ability to produce insecticides, such as soybean, corn, and cotton that have been given herbicide resistance, and rice and tobacco that have been adapted to cold regions.

  Although the penthiopyrad of the present invention can be used as it is, it is usually used by mixing with a carrier, and if necessary, a surfactant, a wetting agent, a sticking agent, a thickening agent, a preservative, a coloring agent, a stabilizing agent. A formulation adjuvant such as a preparation is added, and it is used after timely preparation by a generally known method such as wettable powder, flowable powder, granular wettable powder, powder, emulsion and the like. The content of penthiopyrad as an active ingredient in these preparations is usually 0.01 to 99%, preferably 0.1 to 70% by weight.

  The carrier used in the above preparation can be either solid or liquid as long as it is usually used in agricultural chemical preparations, and is not particularly limited. For example, as a solid carrier, bentonite, montmorillonite, kaolinite, diatomaceous earth, white clay, talc, clay, vermiculite, gypsum, calcium carbonate, silica gel, ammonium sulfate, etc., soybean powder, sawdust, wheat flour, lactose, sucrose, glucose And vegetable organic substances such as urea and urea. Examples of the liquid carrier include aromatic hydrocarbons such as toluene, xylene, cumene and naphthenes, n-paraffin, iso-paraffin, liquid paraffin, kerosene, mineral oil, polybutene and other paraffinic hydrocarbons, acetone, methyl ethyl ketone, etc. Ketones, ethers such as dioxane and diethylene glycol dimethyl ether, alcohols such as ethanol, propanol and ethylene glycol, carbonates such as ethylene carbonate, propylene carbonate and butylene carbonate, aprotic solvents such as dimethylformamide and dimethyl sulfoxide, and water Is mentioned.

  Furthermore, in order to enhance the efficacy of the compound of the present invention, the following adjuvants can be used alone or in combination depending on the purpose in consideration of the dosage form of the preparation, the treatment method and the like. As surfactants usually used for the purpose of emulsifying, dispersing, spreading and wetting in agricultural chemical formulations, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, sucrose fatty acid esters, polyoxyethylene fatty acid esters, Polyoxyethylene resin acid ester, polyoxyethylene fatty acid diester, polyoxyethylene castor oil, polyoxyethylene alkyl ether, polyoxyethylene alkyl phenyl ether, polyoxyethylene dialkyl phenyl ether, formalin condensate of polyoxyethylene alkyl phenyl ether, Polyoxyethylene polyoxypropylene block polymer, alkyl polyoxyethylene polyoxypropylene block polymer ether, alkylphenyl polyoxyethylene polymer Oxypropylene block polymer ether, polyoxyethylene alkylamine, polyoxyethylene fatty acid amide, polyoxyethylene bisphenyl ether, polyoxyalkylene benzyl phenyl ether, polyoxyalkylene styryl phenyl ether, polyoxyalkylene adduct of higher alcohol and polyoxy Nonionic surfactants such as ethylene ether and ester-type silicon and fluorine surfactants, alkyl sulfates, polyoxyethylene alkyl ether sulfates, polyoxyethylene alkyl phenyl ether sulfates, polyoxyethylene benzyl phenyl ether sulfates, polyoxy Ethylene styryl phenyl ether sulfate, polyoxyethylene polyoxypropylene Block polymer sulfate, paraffin sulfonate, alkane sulfonate, AOS, dialkyl sulfosuccinate, alkyl benzene sulfonate, naphthalene sulfonate, dialkyl naphthalene sulfonate, formalin condensate of naphthalene sulfonate, alkyl diphenyl ether disulfonate, lignin sulfonate, polyoxyethylene alkyl phenyl ether sulfonate , Polyoxyethylene alkyl ether sulfosuccinic acid half ester, fatty acid salt, N-methyl-fatty acid sarcosinate, resin acid salt, polyoxyethylene alkyl ether phosphate, polyoxyethylene phenyl ether phosphate, polyoxyethylene dialkyl phenyl ether phosphate, polyoxyethylene Benzylation Phenyl ether phosphate, polyoxyethylene benzylated phenyl phenyl ether phosphate, polyoxyethylene styrylated phenyl ether phosphate, polyoxyethylene styrylated phenyl phenyl ether phosphate, polyoxyethylene polyoxypropylene block polymer phosphate, phosphatidylcholine, phosphatidylethanolimine, alkyl Anionic surfactants such as phosphate, sodium tripolyphosphate, polyanionic polymer surfactants derived from acrylic acid and acrylonitrile, acrylamidomethylpropane sulfonic acid, alkyltrimethylammonium chloride, methylpolyoxyethylenealkylammonium chloride, alkyl N- Methylpyridinium bromide, Cationic surfactants such as nomethylated ammonium chloride, dialkylmethylated ammonium chloride, alkylpentamethylpropyleneamine dichloride, alkyldimethylbenzalkonium chloride, and benzethonium chloride; amphoteric surfactants such as dialkyldiaminoethylbenthine and alkyldimethylbenzylbentain However, it is not limited to these.

  Examples of the binder include sodium alginate, polyvinyl alcohol, gum arabic, CMC sodium, bentonite and the like. Examples of the disintegrant include CMC sodium and croscarmellose sodium, and examples of the stabilizer include hindered phenol-based antioxidants, benzotriazole-based and hindered amine-based ultraviolet absorbers, and the like. Use phosphoric acid, acetic acid, sodium hydroxide as a pH adjuster, or add industrial disinfectants such as 1,2-benzisothiazolin-3-one, antibacterial and antifungal agents, etc. You can also. As a thickener, xanthan gum, guar gum, CMC sodium, gum arabic, polyvinyl alcohol, montmorillonite and the like can also be used. A silicone compound as an antifoaming agent and propylene glycol, ethylene glycol or the like as an antifreezing agent may be used as necessary.

  When the composition containing the penthiopyrad of the present invention as an active ingredient is brought into contact with the plant seed, the plant seed may be immersed in the composition as it is. Moreover, after diluting the composition to be used to a suitable carrier to a suitable concentration, it can be used by dipping, dressing, spraying and smearing the plant seeds. Suitable carriers are liquid carriers of organic solvents such as water or ethanol, bentonite, montmorillonite, kaolinite, diatomaceous earth, white clay, talc, clay, vermiculite, gypsum, calcium carbonate, silica gel, ammonium sulfate and other inorganic substances, soy flour, Sawdust, wheat flour, lactose, sucrose, plant organic substances such as glucose, and solid carriers such as urea are exemplified, but not limited thereto. The amount used for powder coating, spraying, and smearing treatment is usually about 0.05 to 5% of the dry plant seed weight, but such amount is not limited to these ranges. However, it may vary depending on the form of the preparation and the type of plant seed to be treated.

The following examples and test examples illustrate the invention in detail.
Example 1 (Dust)
5 parts of penthiopyrad, 94.5 parts of clay and 0.5 part of Doreles B (Sankyo Co., Ltd.) were mixed and ground uniformly to obtain a powder containing 5% of active ingredient.

Example 2 (wettable powder)
50 parts of penthiopyrad, 1 part of sodium lignin sulfonate, 5 parts of white carbon and 44 parts of diatomaceous earth were mixed and ground to obtain a wettable powder containing 50% of the active ingredient.

Example 3 (Flowable agent)
20 parts of penthiopyrad, 5 parts of propylene glycol, 5 parts of polyoxyethylene oleate, 5 parts of polyoxyethylene diallyl ether sulfate, 0.2 part of silicone antifoaming agent, and 64.8 parts of water are wet-ground with a sand grinder Thus, a flowable agent having an active ingredient of 20% was obtained.

Example 4 (Emulsion)
Ten parts of penthiopyrad, 10 parts of cyclohexane, 60 parts of xylene and 20 parts of Solpol (surfactant manufactured by Toho Chemical) were uniformly dissolved and mixed to obtain an emulsion containing 10% of the active ingredient.

Example 5 (Granule wettable powder)
After uniformly mixing 20 parts of penthiopyrad, 3 parts of CMC sodium, 5 parts of alkyl sulfate ester, and 72 parts of clay, hydromixing, granulation, drying and sizing are carried out to obtain a granular wettable powder containing 20% of the active ingredient. It was.

Test Example 1 Effect of controlling wheat rot rot
Wheat seeds (variety: Norin 61) were mixed well in a polyethylene bag with 0.3% of wheat namagusa smut disease spores collected from diseased ears and inoculated with pathogenic bacteria. Two days after the inoculation, the seeds inoculated with the pathogen and the powder prepared in Example 1 or a commercially available seed fungicide (trihumin wettable powder) were added and mixed well, and then dressed. On the next day of the treatment, seeds treated with the drug and seeds not treated with the drug were sown and grown on two 10 m ² fields. At the mature stage, the presence or absence of disease was examined with the naked eye for all the ears, and the diseased ear rate was calculated by the following formula (Equation 1). The presence or absence of phytotoxicity was also examined with the naked eye. The results are shown in Table 1 (Table 1).

Test Example 2 Rice Blast Control Effect
48 times each of the rice paddies (variety: Koshihikari) naturally infected with a 50-fold, 100-fold, 200-fold dilution of the granular wettable powder prepared in Example 5 or a 300-fold diluted solution of a commercially available seed fungicide (trifumin wettable powder). Time immersion treatment was performed. After soaking (15 ° C., 3 days) and germination (30 ° C., 24 hours), seeds treated with chemicals and seeds not treated with chemicals are sown 100 times per pot in plastic pots. And grown in a greenhouse. After 20 days of cultivation, the presence or absence of disease was examined with the naked eye for all seedlings, and the diseased seedling rate was calculated by the following formula (Equation 2). The presence or absence of phytotoxicity was also examined with the naked eye. The results are shown in Table 2 (Table 2).

Test Example 3 Soybean Rhizoctonia root rot control effect
The flowable agent prepared in Example 3 or a commercially available seed fungicide (trihumin wettable powder) 7.5-fold diluted solution was smeared on soybean seeds (variety: Tachinagaha), spread on a vat, and air-dried until sowing. In addition, after pulverizing Rhizoctonia cultures cultured at 25 ° C. for 7 days in a Fusuma medium, the mixture was mixed with steam-sterilized soil to a weight ratio of 0.1%, and filled in a plastic pot. 5 seeds per pot for soybean seeds that were treated with chemicals and soybean seeds that were not treated with chemicals were sown in a total of 20 pots and grown in a greenhouse. After 7 days of sowing, the number of unemerged seeds and the number of established seedlings after 14 days were examined with the naked eye, and the seedling withering rate was calculated by the following formula (Equation 3). The presence or absence of phytotoxicity was also examined with the naked eye. The results are shown in Table 3 (Table 3).

Test Example 4 Rice Stupid Disease Control Effect
Rice fir contaminated with benomyl-resistant rice idiots (variety: Tanginbo) and a wettable powder prepared in Example 2 or a commercially available seed disinfectant (benrate wettable powder) containing benomyl as an active ingredient Mix well and treat with powder. After soaking (15 ° C., 3 days) and germination (28 ° C., 1 day), seeds treated with chemicals and seeds not treated with chemicals were sown 100 times per pot in plastic pots. And grown in a greenhouse. After 20 days of cultivation, all seedlings were examined for the presence or absence of disease with the naked eye, and the diseased seedling rate was calculated by the following formula (Equation 4). The presence or absence of phytotoxicity was also examined with the naked eye. The results are shown in Table 4 (Table 4).

Claims (6)

  (RS) -N- [2- (1,3-dimethylbutyl) thiophen-3-yl] -1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide (generic name penthiopyrad) as an active ingredient A method for preventing plant diseases, which comprises applying the contained composition to plant seeds.   A method for preventing plant diseases, comprising contacting a plant seed with a composition containing penthiopyrad.   The prevention method according to claim 2, wherein the method of contacting the plant seed is a spraying treatment, a smearing treatment, a dipping treatment or a powder coating treatment on the seed.   Plant seeds are corn, soybean, cotton, rice, sugar beet, wheat, barley, sunflower, tomato, cucumber, eggplant, spinach, sweet pea, pumpkin, sugar cane, tobacco, pepper and rape seed, taro, potato, sweet potato, The method according to claim 1, wherein the seeds are konjac seeds, edible lilies and tulip bulbs.   The method according to claim 4, wherein the plant seed is a seed of a transformed plant.   A plant seed to which a composition containing penthiopyrad is applied.