JP2008029672A - Medicine solution bag package - Google Patents

Medicine solution bag package Download PDF

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Publication number
JP2008029672A
JP2008029672A JP2006207690A JP2006207690A JP2008029672A JP 2008029672 A JP2008029672 A JP 2008029672A JP 2006207690 A JP2006207690 A JP 2006207690A JP 2006207690 A JP2006207690 A JP 2006207690A JP 2008029672 A JP2008029672 A JP 2008029672A
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bag
sheet
inner bag
outer bag
solution filling
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Hiroyoshi Nabeta
啓好 鍋田
Norie Tanihara
範江 谷原
Kenji Kawasaki
賢二 川▲崎▼
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Fuji Seal International Inc
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Fuji Seal International Inc
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Priority to JP2006207690A priority Critical patent/JP2008029672A/en
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Abstract

<P>PROBLEM TO BE SOLVED: To provide a medicine solution bag package which contains and seals a medicine solution bag within a packing bag and keeps the quality of the medicine solution contained in the medicine solution bag by improving the structure of the packing bag so that it hardly gets damaged. <P>SOLUTION: The package comprises the packing bag 2 having a gas barrier functionality which has an outer bag 4 obtained by forming a flexible sheet in a bag-shaped and an inner bag 5 arranged within the outer bag 4 and obtained by forming a flexible sheet in a bag-shaped, and the medicine solution bag 3 received and sealed within the inner bag 5 of the packing bag 2. The medicine solution bag package 1 is characterized by that at least the upper side 5a of the inner bag 5 is adhered to the upper side 4a of the outer bag 4 and the lower side 5b of the inner bag 5 does not adhere to the outer bag 4. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

本発明は、輸血用血液などが充填された血液バッグ、糖質などの栄養素が充填された輸液バッグなどの薬液充填バッグが包装袋に密封収納された薬液充填バッグ包装体に関する。   The present invention relates to a drug solution filling bag package in which a drug solution filling bag such as a blood bag filled with blood for blood transfusion, an infusion solution bag filled with nutrients such as carbohydrates, etc. is hermetically stored in a packaging bag.

従来、輸血用血液や輸液等の薬液を充填する容器としては、ポリエチレン、ポリプロピレンなどの樹脂フィルムを袋状に形成した薬液充填バッグが使用されている。   Conventionally, as a container filled with a chemical solution such as blood for blood transfusion or an infusion solution, a chemical solution filling bag in which a resin film such as polyethylene or polypropylene is formed in a bag shape is used.

薬液は、一般に、空気中の酸素により変色、或いは変質するものが多い。しかしながら、薬液充填バッグを構成する樹脂フィルムは、薬事法上、その材質が限定されているため、ガスバリア性に優れた樹脂フィルムを用いることができないことがある。   In general, many chemical solutions are discolored or denatured by oxygen in the air. However, since the material of the resin film constituting the chemical solution filling bag is limited by the Pharmaceutical Affairs Law, a resin film having excellent gas barrier properties may not be used.

そこで、従来、ガスバリア層を有する内層と耐熱性を有する外層とからなる多層シートを袋状に形成した包装袋内に、薬液充填バッグを密封包装した薬液充填バッグ包装体が知られている(特許文献1)。この包装袋は、内袋の周辺部(4辺部)と外袋の周辺部(4辺部)が接着されている2重袋からなっている。
上記包装袋は、包装袋がガスバリア性を有する内層を備えているので、内層の内部にガスが侵入し難く、従って、薬液充填バッグ内の充填物がガスと接触することを極めて抑制することができる。
さらに、該包装袋が薬液充填バッグを保護するので、薬液充填バッグに対する摩擦や突き刺し事故を防止できる。
Therefore, conventionally, there has been known a chemical solution filling bag package in which a chemical solution filling bag is hermetically packaged in a packaging bag in which a multilayer sheet composed of an inner layer having a gas barrier layer and an outer layer having heat resistance is formed in a bag shape (patent) Reference 1). This packaging bag is composed of a double bag in which the peripheral portion (four sides) of the inner bag and the peripheral portion (four sides) of the outer bag are bonded.
Since the packaging bag includes an inner layer having a gas barrier property, the gas does not easily enter the inside of the inner bag, and therefore the packing in the chemical solution filling bag can be extremely prevented from coming into contact with the gas. it can.
Furthermore, since the packaging bag protects the chemical solution filling bag, it is possible to prevent friction and puncture accidents with respect to the chemical solution filling bag.

上記薬液充填バッグ包装体は、段ボール箱などの梱包箱の底面に、横に寝かした状態で多段状に積み重ねられて梱包されたり、或いは縦に起立させた状態で並列状に梱包されたりして、保管・流通に供されることがある。
しかしながら、上記包装袋は、内袋の周辺部(4辺部)と外袋の周辺部(4辺部)が接着されているので、梱包箱に梱包された薬液充填バッグが流通時に揺れ動くことによって、包装袋の下隅部が折れ曲がったり、或いは、該下隅部に皺が生じる。かかる折れ曲がりなどによって、包装袋に亀裂が生じたり、ピンホールが生じたりする。
包装袋に亀裂などが生じると、そこから包装袋(内袋)の内部へ外気が進入するので、ガスバリア性の包装袋で薬液充填バッグを包装したガスバリア効果が失われる。
The above-mentioned chemical solution filling bag package is stacked and packed in a multistage form on the bottom surface of a packaging box such as a cardboard box, or packed in parallel in a vertically standing state. , May be used for storage and distribution.
However, since the peripheral portion (four sides) of the inner bag and the peripheral portion (four sides) of the outer bag are bonded to each other, the chemical solution filling bag packed in the packing box is swung during distribution. The lower corner of the packaging bag is bent or wrinkles are formed in the lower corner. Such bending causes cracks in the packaging bag or pinholes.
If a crack or the like occurs in the packaging bag, the outside air enters the inside of the packaging bag (inner bag), so that the gas barrier effect of wrapping the chemical solution filled bag with the gas barrier packaging bag is lost.

実用新案登録第2577511号公報Utility Model Registration No. 2577511

そこで、本発明は、薬液充填バッグが包装袋内に密封収納されている薬液充填バッグ包装体に於いて、包装袋を損傷し難い構造に改良して、薬液充填バッグ内の薬液の品質保持を図ることを課題とする。   Therefore, the present invention provides a chemical solution filling bag package in which a chemical solution filling bag is hermetically stored in a packaging bag, and the packaging bag is improved to a structure that does not easily damage, thereby maintaining the quality of the chemical solution in the chemical solution filling bag. The task is to plan.

上記問題点に鑑みて、本発明は、可撓性のシートを袋状に形成した外袋と、外袋の内部に設けられ且つ可撓性のシートを袋状に形成した内袋と、を有するガスバリア性の包装袋と、包装袋の内袋の内部に密封収納された薬液充填バッグと、を具備する包装体であって、内袋の少なくとも上辺部が外袋の上辺部に接着されており、内袋の下辺部が外袋に接着されていない薬液充填バッグ包装体を提供する。   In view of the above problems, the present invention provides an outer bag in which a flexible sheet is formed in a bag shape, and an inner bag provided in the outer bag and formed in a bag shape. A packaging body comprising a gas barrier packaging bag having a chemical solution filling bag sealed and housed inside the inner bag of the packaging bag, wherein at least the upper side of the inner bag is bonded to the upper side of the outer bag In addition, a drug solution-filled bag package in which the lower side portion of the inner bag is not bonded to the outer bag is provided.

上記薬液充填バッグ包装体は、内袋の下辺部が外袋の下辺部に接着されていない。このため、内袋の下方部は、外袋に対して独立し、内袋の下方部が、外袋の下方部の変形に追従し難くなる。従って、本発明の薬液充填バッグ包装体は、その流通時、収納された薬液充填バッグが揺れ動くことによって、外袋の下隅部が折れたり或いは外袋の下隅部に皺が生じても、内袋の下隅部が、外袋に追従し難い。従って、包装体の流通時などに於いて、仮に外袋の下隅部に亀裂或いはピンホールが生じても、内袋に亀裂或いはピンホールが生じることを防止できる。
よって、外袋と内袋の間に外気が進入しても、ガスバリア性の内袋によって、内袋の内部に外気が進入せず、該内袋に密封収納された薬液充填バッグに対するガスバリアを維持できる。
As for the said chemical | medical solution filling bag package, the lower side part of an inner bag is not adhere | attached on the lower side part of an outer bag. For this reason, the lower part of the inner bag is independent of the outer bag, and the lower part of the inner bag is less likely to follow the deformation of the lower part of the outer bag. Therefore, the chemical solution filling bag package according to the present invention has an inner bag even if the lower corner portion of the outer bag breaks or a wrinkle occurs in the lower corner portion of the outer bag due to shaking of the stored chemical solution filling bag during distribution. It is difficult for the lower corner of the to follow the outer bag. Therefore, even when cracks or pinholes occur in the lower corners of the outer bag during distribution of the package, it is possible to prevent cracks or pinholes from occurring in the inner bag.
Therefore, even when outside air enters between the outer bag and the inner bag, the gas barrier inner bag prevents the outside air from entering the inner bag and maintains the gas barrier against the chemical solution filling bag sealed in the inner bag. it can.

本発明の好ましい態様では、上記内袋の下辺部が、内袋を構成するシートを折り返した折辺部で構成されている上記薬液充填バッグ包装体を提供する。
かかる薬液充填バッグ包装体は、内袋の下辺部が、内袋を構成するシートを折り返した折辺部で構成されているので、内袋シートを折り返し、その内袋シートの上辺部及び両側辺部を、外袋シートの上辺部及び両側辺部に熱シールなどの方法で接着することにより、内袋の下方部が外袋に接着されていない包装袋を容易に製造できる。
In a preferred aspect of the present invention, there is provided the medicinal-solution-filled bag packaging body in which the lower side portion of the inner bag is constituted by a folded side portion obtained by folding back a sheet constituting the inner bag.
In such a drug solution-filled bag package, since the lower side portion of the inner bag is composed of a folded side portion obtained by folding back the sheet constituting the inner bag, the inner bag sheet is folded, and the upper side portion and both side sides of the inner bag sheet. By bonding the part to the upper side part and both side parts of the outer bag sheet by a method such as heat sealing, a packaging bag in which the lower part of the inner bag is not bonded to the outer bag can be easily manufactured.

さらに、本発明の好ましい態様では、上記外袋と内袋の間に空気が封入されている上記薬液充填バッグ包装体を提供する。   Furthermore, in a preferred aspect of the present invention, there is provided the drug solution filled bag package in which air is sealed between the outer bag and the inner bag.

かかる薬液充填バッグ包装体は、外袋と内袋の間に空気が封入されているので、内袋の下隅部が、更に外袋に追従し難くなる。従って、包装体の流通時などに於いて、内袋に亀裂或いはピンホールが生じることをより確実に防止できる。   In such a drug solution-filled bag package, since air is sealed between the outer bag and the inner bag, the lower corner portion of the inner bag becomes more difficult to follow the outer bag. Therefore, it is possible to more reliably prevent the inner bag from being cracked or pinholed when the package is distributed.

本発明に係る薬液充填バッグ包装体は、包装袋が外袋とガスバリア性の内袋を備え、内袋の下辺部が外袋に対して非接着とされているので、該包装体の流通時などに於いて、内袋が損傷し難い。従って、本発明の薬液充填バッグ包装体は、内袋のガスバリア効果により、薬液充填バッグ内の薬液の品質を保持することができる。   The medicinal-solution-filled bag package according to the present invention is such that the packaging bag includes an outer bag and a gas barrier inner bag, and the lower side of the inner bag is not bonded to the outer bag. In such cases, the inner bag is not easily damaged. Therefore, the chemical solution filling bag package of the present invention can maintain the quality of the chemical solution in the chemical solution filling bag due to the gas barrier effect of the inner bag.

以下、本発明について、図面を参照しつつ具体的に説明する。
図1〜図4に於いて、1は、2重構造の包装袋2と、該包装袋2内に密封収納された薬液充填バッグ3と、を備える薬液充填バッグ包装体を示す。
Hereinafter, the present invention will be specifically described with reference to the drawings.
1 to 4, reference numeral 1 denotes a chemical solution filling bag package including a double-structure packaging bag 2 and a chemical solution filling bag 3 hermetically sealed in the packaging bag 2.

包装袋2は、可撓性のシートを袋状に形成した外袋4と、外袋4の内部に設けられ且つ可撓性のシートを袋状に形成した内袋5と、を有する。薬液充填バッグ3は、内袋5の内部に密封収納されており、該内袋5は、外袋4の内部に密封収納されている。この内袋5の上辺部5a及び両側辺部5c,5cは、外袋4の上辺部4a及び両側辺部4c,4cにそれぞれ接着されており、一方、内袋5の下辺部5bは、外袋4の下辺部4bに接着されていない。   The packaging bag 2 has an outer bag 4 in which a flexible sheet is formed in a bag shape, and an inner bag 5 provided inside the outer bag 4 and formed in a bag shape. The chemical solution filling bag 3 is hermetically stored inside the inner bag 5, and the inner bag 5 is hermetically stored inside the outer bag 4. The upper side 5a and the side sides 5c, 5c of the inner bag 5 are bonded to the upper side 4a and the side sides 4c, 4c of the outer bag 4, respectively, while the lower side 5b of the inner bag 5 is The bag 4 is not bonded to the lower side 4b.

具体的には、外袋4及び内袋5は、薬液充填バッグ3を収納可能なように薬液充填バッグ3よりも大容量に形成され、例えば、薬液充填バッグ3よりも大面積の正面視略矩形状に形成されている。
外袋4は、略矩形状に形成された2枚の可撓性シート41,41(以下、外袋シートという)からなる。外袋4は、その外袋シート41の周辺部(上辺部41a、下辺部41b及び両側辺部41c、41cの計4辺部)の裏面を接着することにより、密封袋状に形成されている。なお、外袋シート41の上辺部41aの全体及び両側辺部41c,41cの一部は、後述する内袋シート51の上辺部51a及び両側辺部51c,51cを介在させた状態で接着されている。
内袋5は、外袋シート41の幅と同幅で且つ外袋シート41の上下長さの2倍よりも少し短く形成された略矩形状の1枚の可撓性シート51(以下、内袋シートという)からなる。内袋5は、内袋シート51を中央部に於いて折り返した状態(以下、内袋シートを折り返した状態のものを折りシートといい、折り部分を折り辺部という)で、該折りシート51を上記2枚の外袋シート41,41の層間に介在させ、折りシート51の3辺部(折り辺部以外の3辺部である上辺部51a及び両側辺部51c,51c)の裏面を接着することにより、密封袋状に形成されている。この折りシート51の上辺部51a及び両側辺部51c,51cの表面は、外袋シート41の上辺部41a及び両側辺部41c,41cの裏面にそれぞれ接着されている。
Specifically, the outer bag 4 and the inner bag 5 are formed to have a larger capacity than the chemical solution filling bag 3 so that the chemical solution filling bag 3 can be accommodated. It is formed in a rectangular shape.
The outer bag 4 is composed of two flexible sheets 41 and 41 (hereinafter referred to as outer bag sheets) formed in a substantially rectangular shape. The outer bag 4 is formed in a sealed bag shape by adhering the back surfaces of the peripheral portions of the outer bag sheet 41 (the total of the four sides of the upper side portion 41a, the lower side portion 41b, and the both side portions 41c, 41c). . In addition, the whole upper side part 41a of the outer bag sheet 41 and a part of both side parts 41c, 41c are bonded in a state where an upper side part 51a and both side parts 51c, 51c described later are interposed. Yes.
The inner bag 5 is a single, substantially rectangular flexible sheet 51 (hereinafter referred to as an inner bag) that is formed in the same width as the outer bag sheet 41 and slightly shorter than twice the vertical length of the outer bag sheet 41. Bag sheet). The inner bag 5 is a state in which the inner bag sheet 51 is folded at the central portion (hereinafter, the folded state of the inner bag sheet is referred to as a folded sheet, and the folded portion is referred to as a folded side portion). Is interposed between the two outer bag sheets 41 and 41, and the back surfaces of the three sides of the folded sheet 51 (the upper side 51a and the side sides 51c and 51c, which are the three sides other than the folded side) are bonded. By doing so, it is formed in a sealed bag shape. The surfaces of the upper side 51a and the side sides 51c and 51c of the folded sheet 51 are bonded to the back side of the upper side 41a and the side sides 41c and 41c of the outer bag sheet 41, respectively.

従って、内袋5の上辺部5a及び両側辺部5c,5cは、外袋4の上辺部4a及び両側辺部4c,4cにそれぞれ接着されている。一方、内袋5の下辺部5b(すなわち、折返し部)は、外袋4の下辺部4bに接着されておらず、外袋4に対して独立した自由な辺部とされている。
また、外袋4の裏面と内袋5の表面の間には、空間部7が形成されている。特に、内袋5の下辺部5bが外袋4に非接着とされている本発明の包装体1は、内袋5の下辺部5bに於いて、比較的大きな空間部7が形成される。この空間部7には、空気が封入されているが、この空気として、窒素などの不活性ガスが封入されていることが好ましい。さらに、内袋5の内部(薬液充填バッグ3が収納された空間)にも、空気(好ましくは不活性ガス)が封入されている。
内袋5の内部及び/又は外袋4の内部に、不活性ガスなどの空気を封入する場合、包装袋2を製袋する際に空気を封入することができる。また、外袋4の側辺部4c及び/又は内袋5の側辺部5cに逆止弁を設けておき、薬液充填バッグ3を封入した後、逆止弁を通じて、内袋5の内部及び/又は外袋4の内部に、不活性ガスなどの空気を封入することもできる。
Accordingly, the upper side 5a and the side sides 5c, 5c of the inner bag 5 are bonded to the upper side 4a and the side sides 4c, 4c of the outer bag 4, respectively. On the other hand, the lower side portion 5 b (that is, the folded portion) of the inner bag 5 is not bonded to the lower side portion 4 b of the outer bag 4, and is a free side portion independent of the outer bag 4.
A space 7 is formed between the back surface of the outer bag 4 and the surface of the inner bag 5. In particular, in the packaging body 1 of the present invention in which the lower side portion 5b of the inner bag 5 is not bonded to the outer bag 4, a relatively large space portion 7 is formed in the lower side portion 5b of the inner bag 5. Although air is enclosed in this space part 7, it is preferable that inert gas, such as nitrogen, is enclosed as this air. Furthermore, air (preferably inert gas) is also sealed in the inner bag 5 (the space in which the chemical solution filling bag 3 is stored).
When air such as an inert gas is sealed inside the inner bag 5 and / or the outer bag 4, the air can be sealed when the packaging bag 2 is made. In addition, a check valve is provided in the side part 4c of the outer bag 4 and / or the side part 5c of the inner bag 5, and after filling the chemical solution filling bag 3, the inside of the inner bag 5 and In addition, air such as an inert gas can be sealed inside the outer bag 4.

上記外袋シート41及び内袋シート51の接着は、熱シール、接着剤を用いた接着、溶剤を用いた接着などの何れの接着方法でもよいが、簡易に接着できることから熱シールによる接着が好ましい。   The outer bag sheet 41 and the inner bag sheet 51 may be bonded by any method such as heat sealing, bonding using an adhesive, or bonding using a solvent, but bonding by heat sealing is preferable because it can be easily bonded. .

外袋シート41及び内袋シート51は、可撓性を有するシート(なお、シートとは、一般にフィルムと呼ばれるものを含む意味である)が用いられている。外袋シート41及び内袋シート51のうち少なくとも何れか一方は、ガスバリア性を有する層を備える。また、外袋シート41及び内袋シート51のうち少なくとも何れか一方は、突き刺し強度や耐摩擦性を有する層を備えるものが好ましい。例えば、外袋シート41は、突き刺し強度や耐摩擦性を有する層を備えるものが好ましく、内袋シート51は、ガスバリア性を有する層を備えるものが好ましい。また、外袋シート41及び内袋シート51の少なくとも何れか一方は、封入される薬剤の種類に応じて、遮光性をも有する遮光層を備えるものが好ましい。また、外袋シート41及び内袋シート51が熱シールによって接着される場合には、外袋シート41は、最表面に耐熱性を有する層を備えるものが好ましい。また、熱シールによって接着するために、外袋シート41及び内袋シート51の接合面に、熱溶着接着可能なシーラント層が設けられていることが好ましい。   As the outer bag sheet 41 and the inner bag sheet 51, a flexible sheet (the sheet means a film generally including a film) is used. At least one of the outer bag sheet 41 and the inner bag sheet 51 includes a layer having gas barrier properties. In addition, it is preferable that at least one of the outer bag sheet 41 and the inner bag sheet 51 includes a layer having piercing strength and friction resistance. For example, the outer bag sheet 41 is preferably provided with a layer having piercing strength and friction resistance, and the inner bag sheet 51 is preferably provided with a layer having gas barrier properties. Moreover, it is preferable that at least one of the outer bag sheet 41 and the inner bag sheet 51 includes a light-shielding layer having a light-shielding property depending on the type of medicine to be enclosed. Moreover, when the outer bag sheet | seat 41 and the inner bag sheet | seat 51 are adhere | attached by heat sealing, the outer bag sheet | seat 41 has a layer which has heat resistance in the outermost surface. Moreover, in order to adhere | attach by heat sealing, it is preferable that the sealant layer which can be heat-welded and bonded is provided in the joining surface of the outer bag sheet | seat 41 and the inner bag sheet | seat 51. FIG.

上記のような外袋シート41及び内袋シート51の好ましい構成は、図5に示す通りである。
外袋シート41としては、例えば、表面から裏面方向に順に、熱シール温度に耐えうる耐熱性(熱シール温度で溶融しない)及び強度を有する表層411と、1層又は複層からなる中間基材層412と、熱シール用のシーラント層413と、を有するシートを用いることができる。
内袋シート51としては、例えば、表面から裏面方向に順に、熱シール用のシーラント層513と、ガスバリア性を有するバリア層512と、熱シール用のシーラント層513と、を有するシートを用いることができる。
The preferred configurations of the outer bag sheet 41 and the inner bag sheet 51 as described above are as shown in FIG.
As the outer bag sheet 41, for example, an intermediate base material composed of a surface layer 411 having heat resistance (not melted at the heat sealing temperature) and strength capable of withstanding the heat sealing temperature and one layer or multiple layers in order from the front surface to the back surface. A sheet having a layer 412 and a heat sealant layer 413 can be used.
As the inner bag sheet 51, for example, a sheet having a heat sealing sealant layer 513, a gas barrier barrier layer 512, and a heat sealing sealant layer 513 in this order from the front surface to the back surface is used. it can.

上記耐熱性及び強度を有する表層411としては、二軸延伸ポリアミド、二軸延伸ポリエステル、二軸延伸ポリプロピレンなどの樹脂層(フィルムを含む)や、これら樹脂層の積層体が例示できる。表層411の厚みは特に限定されないが、通常、10μm〜40μm程度である。
中間基材層412としては、二軸延伸ポリアミド、二軸延伸ポリエステル、二軸延伸ポリプロピレン、二軸延伸ポリエチレン、ポリスチレンなどの樹脂層(フィルムを含む)や、これら樹脂層の積層体が例示できる。中間基材層412の厚みは特に限定されないが、通常、10μm〜40μm程度である。
シーラント層413,513としては、ポリエチレン、ポリプロピレン、エチレン−酢酸ビニル共重合体などの公知の熱溶着性の樹脂層(フィルムを含む)が例示できる。特に、シーラント層413,513として、ヒートシール性及び強度に優れた直鎖状低密度ポリエチレン(LLDPE)の樹脂層(フィルムを含む)を用いることが好ましい。外袋シート41及び内袋シート51の各シーラント層413,513は、通常、同種の材質が用いられる。シーラント層413,513の厚みは特に限定されないが、通常、15μm〜50μm程度である。
バリア層512としては、ポリ塩化ビニリデン、エチレン−ビニルアルコール共重合体(EVOH)などの樹脂層(フィルムを含む)や、これらの積層体が例示できる。特に、バリア層512として、ガスバリア性に優れたエチレン−酢酸ビニル共重合体けん化物からなる二軸延伸フィルムを用いることが好ましい。バリア層512の厚みは特に限定されないが、通常、10μm〜40μm程度である。
Examples of the surface layer 411 having heat resistance and strength include resin layers (including films) such as biaxially stretched polyamide, biaxially stretched polyester, and biaxially stretched polypropylene, and laminates of these resin layers. Although the thickness of the surface layer 411 is not specifically limited, Usually, it is about 10 micrometers-about 40 micrometers.
Examples of the intermediate base material layer 412 include resin layers (including films) such as biaxially stretched polyamide, biaxially stretched polyester, biaxially stretched polypropylene, biaxially stretched polyethylene, and polystyrene, and laminates of these resin layers. Although the thickness of the intermediate | middle base material layer 412 is not specifically limited, Usually, it is about 10 micrometers-about 40 micrometers.
Examples of the sealant layers 413 and 513 include known heat-weldable resin layers (including films) such as polyethylene, polypropylene, and ethylene-vinyl acetate copolymer. In particular, as the sealant layers 413 and 513, it is preferable to use a resin layer (including a film) of linear low density polyethylene (LLDPE) excellent in heat sealability and strength. For the sealant layers 413 and 513 of the outer bag sheet 41 and the inner bag sheet 51, the same kind of material is usually used. The thickness of the sealant layers 413 and 513 is not particularly limited, but is usually about 15 μm to 50 μm.
Examples of the barrier layer 512 include resin layers (including films) such as polyvinylidene chloride and an ethylene-vinyl alcohol copolymer (EVOH), and laminates thereof. In particular, as the barrier layer 512, it is preferable to use a biaxially stretched film made of a saponified ethylene-vinyl acetate copolymer excellent in gas barrier properties. The thickness of the barrier layer 512 is not particularly limited, but is usually about 10 μm to 40 μm.

外袋シート41及び内袋シート51は、(1)各層を構成する樹脂を製膜してシート状とし、該各層をドライラミネートなどの公知のラミネート法にて積層接着する方法、或いは、(2)各層を構成する樹脂組成物を共押出して積層シートを作製する方法などによって得ることができる。   The outer bag sheet 41 and the inner bag sheet 51 are either (1) a method in which a resin constituting each layer is formed into a sheet and the respective layers are laminated and bonded by a known laminating method such as dry lamination, or (2 ) It can be obtained by a method of producing a laminated sheet by co-extrusion of the resin composition constituting each layer.

上記薬液充填バッグ3は、従来公知のものを用いることができる。薬液充填バッグ3の一例としては、薬事法の規定を満たす樹脂製のフィルム31の周辺部を熱シールなどで接着した密封袋32と、該密封袋32の一部分に設けられた薬剤取出部33と、密封袋32内に封入された薬剤34と、を有する薬液充填バッグが例示される。   A conventionally well-known thing can be used for the said chemical | medical solution filling bag 3. FIG. As an example of the medicinal solution filling bag 3, a sealing bag 32 in which a peripheral portion of a resin film 31 satisfying the provisions of the Pharmaceutical Affairs Law is bonded by heat sealing or the like, and a medicine taking-out portion 33 provided in a part of the sealing bag 32, A chemical solution filling bag having the medicine 34 enclosed in the sealing bag 32 is exemplified.

上記構成の薬液充填バッグ包装体1は、例えば、下記の機械的製造工程によって製造できる。
上記外袋シート41が連続的に繋がった長尺状の外袋シート原反を上下2枚準備する。同様に、上記内袋シート51が連続的に繋がった長尺状の内袋シート原反を準備する。この上下2枚の外袋シート原反の間に、長尺状の内袋シート原反を、その幅方向中央部に於いて長手方向に沿って折り返し且つその折返し部が上下2枚の外袋シート原反の一方の長手辺部よりも内側に位置するようにして挿入すると共に、折り返した内装シート原反の間に、所定間隔を開けて薬液充填バッグ3を挿入する。
次に、上下2枚の外袋シート原反の上下から、外袋シート原反の両方の長手辺部に対して加熱バーを押し当てる。該加熱バーの熱作用によって、外袋シート原反の一方の長手辺部の裏面が互いに接着され(この接着部分は、形成される外袋4の下辺部4bに相当する)、且つ外袋シート原反の他方の長手辺部の裏面と内袋シート原反の折返し部に対向する長手辺部の表裏面とを互いに接着させる(この接着部分は、形成される外袋4及び内袋5の上辺部4a,5aに相当する)。次に、個々の薬液充填バッグ3を区画するように、外袋シート原反の上下から該原反の幅方向に加熱バーを押し当てることによって、外袋シート原反の裏面と内袋シート原反の表裏面を互いに接着させる(この接着部分は、形成される外袋4及び内袋5の両側辺部4c,5cに相当する)。原反の幅方向を接着する際には、内袋シート原反の内側及び外袋シート原反の内側に、不活性ガスなどの空気を封入しながら接着することが好ましい。最後に、個々の薬液充填バッグ3を封入するように、外袋シート原反及び内袋シート原反の幅方向接着部分を切断する。
上記のようにして薬液充填バッグ包装体1を製造できる。
The chemical solution filling bag package 1 having the above-described configuration can be manufactured, for example, by the following mechanical manufacturing process.
Two pieces of the long outer bag sheet original fabric in which the outer bag sheets 41 are continuously connected are prepared. Similarly, a long inner bag sheet raw material in which the inner bag sheets 51 are continuously connected is prepared. Between the two upper and lower outer bag sheets, the long inner bag sheet is folded back along the longitudinal direction at the center in the width direction, and the folded portions are the upper and lower outer bags. The sheet is inserted so as to be located on the inner side of one longitudinal side portion of the sheet original fabric, and the chemical solution filling bag 3 is inserted between the folded interior sheet original fabric with a predetermined interval.
Next, the heating bar is pressed against both longitudinal sides of the outer bag sheet original fabric from above and below the upper and lower outer bag sheet original fabrics. Due to the thermal action of the heating bar, the back surfaces of one longitudinal side of the outer bag sheet original fabric are bonded to each other (this bonded portion corresponds to the lower side 4b of the outer bag 4 to be formed), and the outer bag sheet The back surface of the other longitudinal side portion of the original fabric and the front and back surfaces of the longitudinal side portion facing the folded portion of the inner bag sheet original fabric are adhered to each other (this adhesive portion is formed between the outer bag 4 and the inner bag 5 to be formed). Corresponding to the upper side portions 4a and 5a). Next, the rear surface of the outer bag sheet original fabric and the inner bag sheet original material are pressed by pressing a heating bar in the width direction of the original fabric sheet from above and below so as to divide each chemical solution filling bag 3. The opposite front and back surfaces are bonded to each other (this bonded portion corresponds to both side portions 4c and 5c of the formed outer bag 4 and inner bag 5). When adhering the width direction of the original fabric, it is preferable to adhere the inside of the inner bag sheet original fabric and the inner side of the outer bag sheet original material while enclosing air such as an inert gas. Finally, the width direction adhesion part of an outer bag sheet | seat original fabric and an inner bag sheet | seat original fabric is cut | disconnected so that each chemical | medical solution filling bag 3 may be enclosed.
The chemical solution filling bag package 1 can be manufactured as described above.

また、薬液充填バッグ包装体1の製造方法の変形例として、下記の方法が挙げられる。
すなわち、上記外袋シート41が連続的に繋がった長尺状の外袋シート原反を上下2枚準備する。同様に、上記内袋シート51が連続的に繋がった長尺状の内袋シート原反を準備する。この上下2枚の外袋シート原反の間に、長尺状の内袋シート原反を、その幅方向中央部に於いて長手方向に沿って折り返し且つその折返し部が上下2枚の外袋シート原反の一方の長手辺部よりも内側に位置するようにして挿入する。
次に、上下2枚の外袋シート原反の上下から、外袋シート原反の一方の長手辺部に対して加熱バーを押し当て、外袋シート原反の一方の長手辺部の裏面を互いに接着する(この接着部分は、形成される外袋4の下辺部4bに相当する)。さらに、薬液充填バッグ3を収納する領域を区画するように、外袋シート原反の上下から該原反の幅方向に加熱バーを押し当てることによって、外袋シート原反の裏面と内袋シート原反の表裏面を幅方向に互いに接着する(この接着部分は、形成される外袋4及び内袋5の両側辺部4c,5cに相当する)。この状態の原反を、一旦ロール状に巻き取る。このロールから原反を引き出し、未接着の他方の長手辺部から、内袋シート原反の内側に薬液充填バッグ3を挿入する。次に、外袋シート原反の裏面と内袋シート原反の折返し部に対向する他方の長手辺部の表裏面とを互いに接着する(この接着部分は、形成される外袋4及び内袋5の上辺部4a,5aに相当する)。この他方の長手辺部を接着する際には、内袋シート原反の内側及び外袋シート原反の内側に、不活性ガスなどの空気を封入しながら接着することが好ましい。最後に、外袋シート原反及び内袋シート原反の幅方向接着部分を切断することによって、個々の薬液充填バッグ包装体1を得ることができる。
また、その他の製造方法として、上記のように、外袋シート原反の裏面と内袋シート原反の表裏面を幅方向に互いに接着した後、この外袋シート原反及び内袋シート原反の幅方向接着部分を切断することにより、枚葉態様の包装袋を得る。この個々の包装袋の上辺部から、薬液充填バッグ3を挿入し、該上辺部を接着することによって、薬液充填バッグ包装体1を製造することもできる。
Moreover, the following method is mentioned as a modification of the manufacturing method of the chemical | medical solution filling bag package 1.
That is, two upper and lower sheets of the outer bag sheet raw material in which the outer bag sheets 41 are continuously connected are prepared. Similarly, a long inner bag sheet raw material in which the inner bag sheets 51 are continuously connected is prepared. Between the two upper and lower outer bag sheets, the long inner bag sheet is folded back along the longitudinal direction at the center in the width direction, and the folded portions are the upper and lower outer bags. The sheet is inserted so as to be located on the inner side of one longitudinal side portion of the original sheet.
Next, from the top and bottom of the two upper and lower outer bag sheets, the heating bar is pressed against one longitudinal side of the outer bag sheet, and the back of one longitudinal side of the outer bag sheet is Adhere to each other (this adhesion portion corresponds to the lower side 4b of the outer bag 4 to be formed). Further, by pressing a heating bar in the width direction of the original sheet from above and below the original sheet of the outer bag sheet so as to divide an area for storing the chemical solution filling bag 3, the back surface of the outer bag sheet original sheet and the inner bag sheet The front and back surfaces of the original fabric are bonded to each other in the width direction (this bonded portion corresponds to both side portions 4c and 5c of the outer bag 4 and the inner bag 5 to be formed). The raw material in this state is once wound up into a roll. The original fabric is pulled out from the roll, and the chemical solution filling bag 3 is inserted into the inner bag sheet original fabric from the other unbonded longitudinal side. Next, the back surface of the outer bag sheet original fabric and the front and back surfaces of the other long side part facing the folded portion of the inner bag sheet original fabric are bonded to each other (this adhesive portion is formed by the outer bag 4 and the inner bag formed). 5 corresponds to the upper side portions 4a and 5a). When bonding the other long side portion, it is preferable to bond the inside of the inner bag sheet original fabric and the outer bag sheet original fabric while enclosing air such as an inert gas. Finally, each chemical | medical solution filling bag package 1 can be obtained by cut | disconnecting the width direction adhesion part of an outer bag sheet | seat original fabric and an inner bag sheet | seat original fabric.
As another manufacturing method, as described above, the back surface of the outer bag sheet and the front and back surfaces of the inner bag sheet are bonded to each other in the width direction, and then the outer bag sheet and inner bag sheet A sheet bag-like packaging bag is obtained by cutting the width direction adhesive portion. The chemical solution filling bag package 1 can also be manufactured by inserting the chemical solution filling bag 3 from the upper side portion of each individual packaging bag and bonding the upper side portion.

上記薬液充填バッグ包装体1は、内袋5の下辺部5bが、外袋4の下辺部4bに接着されていないため、内袋5の下辺部5bは、外袋4に対して独立している。従って、薬液充填バッグ包装体1の流通時、収納された薬液充填バッグ3が揺れ動くことによって、外袋4の下隅部が折れたり或いは外袋4の下隅部に皺が生じても、内袋5の下隅部が、外袋に追従し難い。よって、包装体1の流通時などに於いて、仮に外袋4の下隅部に亀裂或いはピンホールが生じても、内袋5にまで亀裂或いはピンホールが生じることを防止できる。
このため、外袋4と内袋5の間に外気が進入しても、内袋5の内部に外気が進入せず、該内袋に密封収納された薬液充填バッグに対するガスバリアを維持できる。
また、薬液充填バッグ包装体1は、外袋4と内袋5の間に空気が封入されているので、内袋5の下隅部が、更に外袋4に追従し難くなる。従って、包装体1の流通時などに於いて、内袋5に亀裂或いはピンホールが生じることをより確実に防止できる。
Since the lower side part 5b of the inner bag 5 is not bonded to the lower side part 4b of the outer bag 4, the lower side part 5b of the inner bag 5 is independent of the outer bag 4 in the chemical solution filling bag package 1 described above. Yes. Therefore, even if the stored chemical solution filling bag 3 swings during distribution of the chemical solution filling bag package 1, even if the lower corner portion of the outer bag 4 breaks or wrinkles occur in the lower corner portion of the outer bag 4, the inner bag 5. It is difficult for the lower corner of the to follow the outer bag. Therefore, even when a crack or a pinhole is generated in the lower corner portion of the outer bag 4 during distribution of the package 1, it is possible to prevent the inner bag 5 from being cracked or pinholed.
For this reason, even if outside air enters between the outer bag 4 and the inner bag 5, the outside air does not enter the inside of the inner bag 5, and it is possible to maintain a gas barrier with respect to the chemical solution filling bag sealed and stored in the inner bag.
In addition, since the medicinal-solution-filled bag package 1 has air sealed between the outer bag 4 and the inner bag 5, the lower corner portion of the inner bag 5 becomes more difficult to follow the outer bag 4. Accordingly, it is possible to more reliably prevent the inner bag 5 from being cracked or pinholes when the package 1 is distributed.

次に、本発明の変形例を説明する。
ただし、上記実施形態と同様の構成については説明を省略し、用語及び図番を援用することがある。
上記実施形態では、内袋5は、正面視矩形状に形成されているが、例えば、図6に示すように、内袋5の下辺部5bが円弧状に形成されていている包装袋2でもよい。また、図7に示すように、内袋5の下辺部5bの両側が、上向き傾斜状に形成されている包装袋2でもよい。
Next, a modified example of the present invention will be described.
However, the description of the same configuration as that in the above embodiment may be omitted, and terms and figure numbers may be used.
In the above embodiment, the inner bag 5 is formed in a rectangular shape when viewed from the front. For example, as shown in FIG. 6, even in the packaging bag 2 in which the lower side portion 5b of the inner bag 5 is formed in an arc shape. Good. Moreover, as shown in FIG. 7, the packaging bag 2 by which the both sides of the lower side part 5b of the inner bag 5 were formed in the upward inclined form may be sufficient.

さらに、上記実施形態では、内袋5の上辺部5a及び両側辺部5c,5cが外袋4に接着されているが、例えば、図8に示すように、内袋5の下辺部5b及び両側辺部5c,5cが外袋4の下辺部4b及び両側辺部4c,4cに接着されておらず且つ内袋5の上辺部5aが外袋4の上辺部4aに接着されている包装袋2でもよい。   Furthermore, in the said embodiment, although the upper side part 5a and the both side parts 5c and 5c of the inner bag 5 are adhere | attached on the outer bag 4, as shown in FIG. 8, for example, the lower side part 5b and both sides of the inner bag 5 Packaging bag 2 in which sides 5c and 5c are not bonded to lower side 4b and both sides 4c and 4c of outer bag 4 and upper side 5a of inner bag 5 is bonded to upper side 4a of outer bag 4 But you can.

また、上記実施形態では、外袋4は、2枚のシートの周辺部を接着することにより袋状に形成されているが、外袋4は、例えば上記内袋5の如く、1枚のシートを適宜接着することにより袋状に形成されていてもよい。
さらに、上記実施形態では、内袋5は、1枚のシートを折り返してその3辺部を接着することにより密封袋状に形成されているが、内袋5は、例えば上記外袋4の如く、2枚のシートを適宜接着することにより密封袋状に形成されていてもよい。
Moreover, in the said embodiment, although the outer bag 4 is formed in the bag shape by adhere | attaching the peripheral part of two sheets, the outer bag 4 is one sheet | seat like the said inner bag 5, for example. May be formed into a bag shape by appropriately adhering.
Further, in the above embodiment, the inner bag 5 is formed in a sealed bag shape by folding one sheet and bonding its three sides, but the inner bag 5 is, for example, like the outer bag 4 described above. It may be formed in a sealed bag shape by appropriately bonding two sheets.

薬液充填バッグ包装体を示す正面図。なお、内袋及び薬液充填バッグは、外袋の内部に設けられているが、そのうち薬液充填バッグは、(破線で表さずに)実線で表している。また、外袋、内袋及び薬液充填バッグを構成するシートの接着部分を、網掛けで示している(図6〜図8も同様)。The front view which shows a chemical | medical solution filling bag packaging body. The inner bag and the chemical solution filling bag are provided inside the outer bag, and the chemical solution filling bag is indicated by a solid line (not indicated by a broken line). Moreover, the adhesion | attachment part of the sheet | seat which comprises an outer bag, an inner bag, and a chemical | medical solution filling bag is shown by shading (FIGS. 6-8 are also the same). 図1のA−A線縦断面図。FIG. 2 is a longitudinal sectional view taken along line AA in FIG. 1. 図1のB−B線断面図。ただし、中央部分を省略している。FIG. 3 is a sectional view taken along line BB in FIG. 1. However, the central part is omitted. 図1のC−C線断面図。The CC sectional view taken on the line of FIG. (a)は、外袋シートの層構成の詳細を示す断面図、(b)は、内袋シートの層構成の詳細を示す断面図。(A) is sectional drawing which shows the detail of the layer structure of an outer bag sheet | seat, (b) is sectional drawing which shows the detail of the layer structure of an inner bag sheet | seat. 変形例に係る薬液充填バッグ包装体を示す正面図。The front view which shows the chemical | medical solution filling bag package which concerns on a modification. 変形例に係る薬液充填バッグ包装体を示す正面図。The front view which shows the chemical | medical solution filling bag package which concerns on a modification. 変形例に係る薬液充填バッグ包装体を示す正面図。The front view which shows the chemical | medical solution filling bag package which concerns on a modification.

符号の説明Explanation of symbols

1…薬液充填バッグ包装体、2…包装袋、3…薬液充填バッグ、4…外袋、4a…外袋の上辺部、4b…外袋の下辺部、5…内袋、5a…内袋の上辺部、5b…内袋の下辺部、7…空間部
DESCRIPTION OF SYMBOLS 1 ... Chemical liquid filling bag package, 2 ... Packaging bag, 3 ... Chemical liquid filling bag, 4 ... Outer bag, 4a ... Upper side part of outer bag, 4b ... Lower side part of outer bag, 5 ... Inner bag, 5a ... Inner bag Upper side, 5b ... Lower side of inner bag, 7 ... Space

Claims (3)

可撓性のシートを袋状に形成した外袋と、外袋の内部に設けられ且つ可撓性のシートを袋状に形成したガスバリア性の内袋と、を有する包装袋と、包装袋の内袋の内部に密封収納された薬液充填バッグと、を具備する包装体であって、
内袋の少なくとも上辺部が外袋の上辺部に接着されており、内袋の下辺部が外袋に接着されていないことを特徴とする薬液充填バッグ包装体。
A packaging bag having an outer bag formed of a flexible sheet in a bag shape, and a gas barrier inner bag provided inside the outer bag and formed of a flexible sheet in a bag shape; A packaging body comprising a chemical solution filling bag hermetically sealed in the inner bag,
A drug solution-filled bag package characterized in that at least the upper side of the inner bag is bonded to the upper side of the outer bag, and the lower side of the inner bag is not bonded to the outer bag.
内袋の下辺部が、内袋を構成するシートを折り返した折り辺部で構成されている請求項1に記載の薬液充填バッグ包装体。   The chemical | medical solution filling bag packaging body of Claim 1 comprised by the folded side part which turned down the sheet | seat which comprises an inner bag in the lower side part of the inner bag. 外袋と内袋の間に、空気が封入されている請求項1または2に記載の薬液充填バッグ包装体。
The drug solution-filled bag package according to claim 1 or 2, wherein air is sealed between the outer bag and the inner bag.
JP2006207690A 2006-07-31 2006-07-31 Medicine solution bag package Pending JP2008029672A (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103142409A (en) * 2013-03-29 2013-06-12 回音必集团(江西)东亚制药有限公司 Method for guarteeing product quality of injection for plastic bottle or soft bag
CN103230338A (en) * 2013-03-29 2013-08-07 回音必集团(江西)东亚制药有限公司 Method for stabilizing product quality of sodium bicarbonate injection
CN103431996A (en) * 2013-08-30 2013-12-11 山东华鲁制药有限公司 Transfusion plastic container for containing medicine liquid
JP2018144888A (en) * 2017-08-09 2018-09-20 花王株式会社 container
JP2019026367A (en) * 2017-08-02 2019-02-21 大日本印刷株式会社 Article and liquid storage bag
JP2022043151A (en) * 2017-08-02 2022-03-15 大日本印刷株式会社 Article and liquid receiving bag
US11332292B2 (en) 2017-03-07 2022-05-17 Kao Corporation Container

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JPH03108641A (en) * 1989-09-22 1991-05-08 Hitachi Ltd Fluorescent photometer

Patent Citations (1)

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JPH03108641A (en) * 1989-09-22 1991-05-08 Hitachi Ltd Fluorescent photometer

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103142409A (en) * 2013-03-29 2013-06-12 回音必集团(江西)东亚制药有限公司 Method for guarteeing product quality of injection for plastic bottle or soft bag
CN103230338A (en) * 2013-03-29 2013-08-07 回音必集团(江西)东亚制药有限公司 Method for stabilizing product quality of sodium bicarbonate injection
CN103431996A (en) * 2013-08-30 2013-12-11 山东华鲁制药有限公司 Transfusion plastic container for containing medicine liquid
US11332292B2 (en) 2017-03-07 2022-05-17 Kao Corporation Container
JP2019026367A (en) * 2017-08-02 2019-02-21 大日本印刷株式会社 Article and liquid storage bag
JP2022043151A (en) * 2017-08-02 2022-03-15 大日本印刷株式会社 Article and liquid receiving bag
JP7207513B2 (en) 2017-08-02 2023-01-18 大日本印刷株式会社 Goods and liquid storage bags
JP2018144888A (en) * 2017-08-09 2018-09-20 花王株式会社 container

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