CN103431996A - Transfusion plastic container for containing medicine liquid - Google Patents

Transfusion plastic container for containing medicine liquid Download PDF

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Publication number
CN103431996A
CN103431996A CN2013103856758A CN201310385675A CN103431996A CN 103431996 A CN103431996 A CN 103431996A CN 2013103856758 A CN2013103856758 A CN 2013103856758A CN 201310385675 A CN201310385675 A CN 201310385675A CN 103431996 A CN103431996 A CN 103431996A
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CN
China
Prior art keywords
gas
infusion plastic
medicinal liquid
bag
container
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Pending
Application number
CN2013103856758A
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Chinese (zh)
Inventor
于洪华
赵奇
杨杰
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SHANGDONG HUALU PHARMACEUTICAL CO Ltd
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SHANGDONG HUALU PHARMACEUTICAL CO Ltd
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Priority to CN2013103856758A priority Critical patent/CN103431996A/en
Publication of CN103431996A publication Critical patent/CN103431996A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a transfusion plastic container for containing medicine liquid. An inner transfusion plastic bag is used for containing the medicine liquid, an outer gas separating bag is arranged on the exterior of the inner transfusion plastic bag and used for preventing gas in the inner transfusion plastic bag from effusion, the situation that the quality of the medicine liquid is not changed is guaranteed, a cavity is formed between the inner transfusion plastic bag and the outer gas separating bag, and the cavity is filled with the gas determined according to the medicine characteristics and the process control situation. According to the transfusion plastic container, through corresponding measures of adjusting technological parameters such as PH and the like, medicine can be guaranteed to reach standard requests of products, the medicine can be guaranteed to be kept relatively stable, the medicine liquid can be effectively guaranteed to achieve the standard requests of the products, and the problem that the quality of the medicine liquid frequently changes so that the medicine liquid cannot achieve the standard request due to the air permeability of a plastic bag when the plastic bag is filled with many kinds of medicine liquid at present is solved. In addition, the transfusion plastic container is simple in structure and high in practicability, has high popularization and application value.

Description

A kind of container of the infusion plastic for the splendid attire medicinal liquid
Technical field
The invention belongs to the medical devices technical field, relate in particular to a kind of container of the infusion plastic for the splendid attire medicinal liquid.
Background technology
At present, a lot of medicinal liquids are contained in plastic bag, due to the breathability of plastic bag, often cause the quality of medicinal liquid to change, and make medicinal liquid not reach standard-required.Such as Tegafur and Sodium Chloride Injection, sodium bicarbonate injection etc., easily produce gas in sterilization process or in depositing, gas oozes out from bag, affects the quality of medicinal liquid.
Summary of the invention
The object of the present invention is to provide a kind of container of the infusion plastic for the splendid attire medicinal liquid, being intended to solve at present a lot of medicinal liquids is contained in plastic bag, due to the breathability of plastic bag, often cause the quality of medicinal liquid to change, and make medicinal liquid not reach the problem of standard-required.
The present invention realizes like this, a kind of container of the infusion plastic for the splendid attire medicinal liquid, this infusion plastic container comprises: for infusion plastic inner bag and the infusion bag fitting of splendid attire medicinal liquid, this infusion plastic container also comprises: the outside that is arranged on described infusion plastic inner bag, for stoping described infusion plastic inner bag gas to ooze out, guarantee the gas barrier outer bag that quality of liquid medicine does not change.
Further, described infusion plastic inner bag material is one or more of polyethylene, ethene improved, polyester, modified polypropene, lipin polymer, poly alpha olefin intermingling material, ethene improved-acrylic polymers, ethylene methacrylate polymer, polyolefin blend alloy, modified thermoplastic elastomer etc.
Further, be formed with cavity between described infusion plastic inner bag and described gas barrier outer bag.
Further, in the cavity between described infusion plastic inner bag and described gas barrier outer bag, be filled with according to medicine character and the determined gas of technology controlling and process situation.
Further, the cavity between described infusion plastic inner bag and described gas barrier outer bag, according to medicine character and technology controlling and process situation, also inflatable body not, as regulated the corresponding measure such as pH, guarantee that medicine reaches the standard-required of product by the adjusting process parameter, guarantee that medicine is stable to get final product.
Infusion plastic for splendid attire medicinal liquid container provided by the invention, the infusion plastic inner bag is for the splendid attire medicinal liquid, the gas barrier outer bag is arranged on the outside of infusion plastic inner bag, for stoping described infusion plastic inner bag gas to ooze out, guarantee that quality of liquid medicine does not change, be formed with cavity between infusion plastic inner bag and gas barrier outer bag, in cavity, can be filled with according to medicine character and the determined gas of technology controlling and process situation, the identical gas of gas can filling discharged with medicinal liquid, as carbon dioxide etc.; Easily the medicinal liquid of oxidation can also the filling noble gas, as nitrogen etc.; According to medicine character and technology controlling and process situation, also inflatable body not, as regulated the corresponding measure such as pH, guarantee that medicine reaches the standard-required of product by the adjusting process parameter, guarantees that medicine keeps relative stability to get final product.This infusion plastic container products modern design, simple in structure, safe and reliable, effectively guaranteed that medicinal liquid reaches the standard-required of product, solved at present a lot of medicinal liquids and be contained in plastic bag, due to the breathability of plastic bag, often cause the quality of medicinal liquid to change, and make medicinal liquid not reach the problem of standard-required, and practical, there is stronger propagation and employment and be worth.
The accompanying drawing explanation
Fig. 1 is the structural representation of the container of the infusion plastic for the splendid attire medicinal liquid that provides of the embodiment of the present invention;
In figure: 1, infusion plastic inner bag and infusion bag fitting; 2, gas barrier outer bag; 3, cavity.
The specific embodiment
In order to make purpose of the present invention, technical scheme and advantage clearer, below in conjunction with drawings and Examples, the present invention is further elaborated.Should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not intended to limit the present invention.
Fig. 1 shows the structure of the container of the infusion plastic for the splendid attire medicinal liquid that the embodiment of the present invention provides.For convenience of explanation, only show the part relevant to the embodiment of the present invention.
This infusion plastic container comprises: for infusion plastic inner bag 1 and the infusion bag fitting of splendid attire medicinal liquid, this infusion plastic container also comprises: the outside that is arranged on infusion plastic inner bag 1, for stoping infusion plastic inner bag 1 gas to ooze out, guarantee the gas barrier outer bag 2 that quality of liquid medicine does not change.
In embodiments of the present invention, described infusion plastic inner bag material is one or more of polyethylene, ethene improved, polyester, modified polypropene, lipin polymer, poly alpha olefin intermingling material, ethene improved-acrylic polymers, ethylene methacrylate polymer, polyolefin blend alloy, modified thermoplastic elastomer etc.
In embodiments of the present invention, be formed with cavity 3 between infusion plastic inner bag 1 and gas barrier outer bag 2.
In embodiments of the present invention, in the cavity 3 between infusion plastic inner bag 1 and gas barrier outer bag 2, be filled with according to medicine character and the determined gas of technology controlling and process situation, the identical gas of gas can filling discharged with medicinal liquid, as carbon dioxide etc.; The all right filling noble gas of the medicinal liquid of easy oxidation, nitrogen etc.According to medicine character and technology controlling and process situation, also inflatable body not, as regulated the corresponding measure such as pH, guarantee that medicine reaches the standard-required of product by the adjusting process parameter, guarantees that medicine keeps relative stability to get final product.
Below in conjunction with drawings and the specific embodiments, application principle of the present invention is further described.
As shown in Figure 1, a kind of container of the infusion plastic for the splendid attire medicinal liquid, comprise: infusion plastic inner bag 1 (comprising that the approval of national drug food Surveillance Authority is used in the various bag plastic containers of infusion products) and gas barrier outer bag 2 are formed with cavity 3 between infusion plastic inner bag 1 and gas barrier outer bag 2.
Manufacturing process: at first by the transfusion processing technology, make infusion plastic inner bag 1, liquid drug, soldering opening pipe and composite cover again, advance the sterilizing cabinet sterilizing, can in cabinet, fill identical with the gas of medicinal liquid release in right amount gas and be filled with appropriate compressed air in sterilization process, or filling with inert gas (or compressed air) only, and keep in cabinet suitably pressure.
After sterilizing finishes, in infusion plastic inner bag 1 outer setting gas barrier outer bag 2, can be according to medicine character and technology controlling and process situation filling gas in the cavity 3 formed between infusion plastic inner bag 1 and gas barrier outer bag 2, the identical gas of gas can filling discharged with medicinal liquid, as carbon dioxide etc.; Easily the medicinal liquid of oxidation can the filling noble gas, as nitrogen etc.As unnecessarily also can not filled, as regulated the corresponding measure such as pH, guarantee that medicine reaches the standard-required of product by the adjusting process parameter, guarantee that medicine keeps relative stability to get final product.
Between infusion plastic inner bag 1 and gas barrier outer bag 2 during filling gas, can select sterilizing again after gas-flow closure between infusion plastic inner bag 1 and gas barrier outer bag 2, after also can selecting 1 sterilizing of infusion plastic inner bag to offer for sale, outer setting gas barrier outer bag 2, gas-flow closure again, also can select in sterilization process, to filling gas or compressed air in cabinet, gas barrier outer bag 2 gas-flow closure to be set after offeing for sale again.
Can select one or more situations of said circumstances and use according to medicine character and technology controlling and process situation, also can be only inflatable body by gas barrier outer bag 2 and not, pass through the adjusting process parameter as corresponding measures such as adjusting pH, guarantee that medicine reaches the standard-required of product, guarantee that medicine keeps relative stability to get final product.
The material of infusion plastic inner bag 1 is one or more of polyethylene, ethene improved, polyester, modified polypropene, lipin polymer, poly alpha olefin intermingling material, ethene improved-acrylic polymers, ethylene methacrylate polymer, polyolefin blend alloy, modified thermoplastic elastomer etc.
The invention has the beneficial effects as follows:
Due to gas filling between gas barrier outer bag 2 and infusion plastic inner bag 1, identical or the noble gas of the gas that this gas and medicinal liquid discharge, so stop infusion plastic inner bag 1 gas to ooze out, thereby guarantee the quality of medicinal liquid, according to medicine character and technology controlling and process situation, also can be only in infusion plastic inner bag 1 outer setting gas barrier outer bag 2, and in cavity 3 inflatable body not.This product design novelty, simple in structure, safe and reliable, guaranteed that medicinal liquid reaches the standard-required of product.
The container of the infusion plastic for the splendid attire medicinal liquid that the embodiment of the present invention provides, infusion plastic inner bag 1 is for the splendid attire medicinal liquid, gas barrier outer bag 2 is arranged on the outside of infusion plastic inner bag 1, for stoping infusion plastic inner bag 1 gas to ooze out, guarantee that quality of liquid medicine does not change, be formed with cavity 3 between infusion plastic inner bag 1 and gas barrier outer bag 2, in cavity 3, be filled with according to medicine character and the determined gas of technology controlling and process situation, the identical gas of gas can filling discharged with medicinal liquid, as carbon dioxide etc.; Easily the medicinal liquid of oxidation can also the filling noble gas, as nitrogen etc.According to medicine character and technology controlling and process situation, also inflatable body not, as regulated the corresponding measure such as pH, guarantee that medicine reaches the standard-required of product by the adjusting process parameter, guarantees that medicine keeps relative stability to get final product.This infusion plastic container products modern design, simple in structure, safe and reliable, effectively guaranteed that medicinal liquid reaches the standard-required of product, solved at present a lot of medicinal liquids and be contained in plastic bag, breathability due to plastic bag, often cause the quality of medicinal liquid to change, and make medicinal liquid not reach the problem of standard-required, simple in structure, practical, there is stronger propagation and employment and be worth.
These are only preferred embodiment of the present invention, not in order to limit the present invention, all any modifications of doing within the spirit and principles in the present invention, be equal to and replace and improvement etc., within all should being included in protection scope of the present invention.

Claims (6)

1. the container of the infusion plastic for the splendid attire medicinal liquid, it is characterized in that, should comprise for the infusion plastic container of splendid attire medicinal liquid: for infusion plastic inner bag and the infusion bag fitting of splendid attire medicinal liquid, this infusion plastic container also comprises: the outside that is arranged on described infusion plastic inner bag, for stoping described infusion plastic inner bag gas to ooze out, guarantee the gas barrier outer bag that quality of liquid medicine does not change.
2. a kind of container of the infusion plastic for the splendid attire medicinal liquid as claimed in claim 1, it is characterized in that, described infusion plastic inner bag material is one or more of polyethylene, ethene improved, polyester, modified polypropene, lipin polymer, poly alpha olefin intermingling material, ethene improved-acrylic polymers, ethylene methacrylate polymer, polyolefin blend alloy, modified thermoplastic elastomer.
3. a kind of container of the infusion plastic for the splendid attire medicinal liquid as claimed in claim 1, is characterized in that, between described infusion plastic inner bag and described gas barrier outer bag, is formed with cavity.
4. a kind of container of the infusion plastic for the splendid attire medicinal liquid as claimed in claim 1, it is characterized in that, between described infusion plastic inner bag and described gas barrier outer bag during filling gas, can select sterilizing again after gas-flow closure, also can select after sterilizing gas-flow closure again, also can select in sterilization process, to filling specific gas or compressed air in cabinet, gas barrier outer bag gas-flow closure to be set after offeing for sale again.
5. a kind of container of the infusion plastic for the splendid attire medicinal liquid as claimed in claim 3, it is characterized in that, be filled with according to medicine character and the determined gas of technology controlling and process situation the identical gas of gas can filling discharged with medicinal liquid in cavity between described infusion plastic inner bag and described gas barrier outer bag; Easily the medicinal liquid of oxidation can also the filling noble gas.
6. a kind of container of the infusion plastic for the splendid attire medicinal liquid as claimed in claim 3, it is characterized in that, also inflatable body not in cavity between described infusion plastic inner bag and described gas barrier outer bag, by regulating the corresponding measure of PH, guarantee that medicine reaches the standard-required of product, guarantee that medicine keeps relative stability to get final product.
CN2013103856758A 2013-08-30 2013-08-30 Transfusion plastic container for containing medicine liquid Pending CN103431996A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104107140A (en) * 2014-06-23 2014-10-22 武汉药谷生物工程有限公司 Flexible package for injections including sodium bicarbonate
CN105167995A (en) * 2015-08-14 2015-12-23 石家庄四药有限公司 Sodium bicarbonate injection double-layer aseptic vertical bag package system and preparation method thereof
CN107651251A (en) * 2017-08-31 2018-02-02 芜湖杨燕制药有限公司 A kind of insect-expelling saligna injection liquid filling sterilizing technique

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4548605A (en) * 1982-10-30 1985-10-22 Terumo Kabushiki Kaisha Method for manufacturing plastic container containing infusion solution which does not allow deterioration of infusion solution for long period of time
EP1541113A1 (en) * 2002-07-30 2005-06-15 Senju Pharmaceutical Co., Ltd. Packaged container for ocular perfusion/washing solution and process for producing the same
CN2915109Y (en) * 2006-06-16 2007-06-27 湖南千山制药机械股份有限公司 Hard-mouth infusion bag package provided with protective bag and piercing function-possessed medicine mixing mouth
JP2008029672A (en) * 2006-07-31 2008-02-14 Fuji Seal International Inc Medicine solution bag package
CN101461756A (en) * 2007-12-17 2009-06-24 丽珠集团利民制药厂 Medicine liquid flexible package and method for packing the same
CN101827570A (en) * 2007-10-16 2010-09-08 中央医疗服务有限公司 Double packing materials for infusion solution
CN101874772A (en) * 2010-05-31 2010-11-03 青岛华仁药业股份有限公司 Preparation process for soft bag injection and product
CN102068379A (en) * 2011-01-19 2011-05-25 四川科伦药业股份有限公司 Dual-cavity aseptic bag and manufacturing method thereof
CN102090976A (en) * 2011-01-19 2011-06-15 四川科伦药业股份有限公司 Three-cavity sterile bag and preparation method thereof
CN102488617A (en) * 2011-11-22 2012-06-13 四川科伦药物研究有限公司 Sodium bicarbonate injection plastic soft bag package and preparation method thereof

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4548605A (en) * 1982-10-30 1985-10-22 Terumo Kabushiki Kaisha Method for manufacturing plastic container containing infusion solution which does not allow deterioration of infusion solution for long period of time
EP1541113A1 (en) * 2002-07-30 2005-06-15 Senju Pharmaceutical Co., Ltd. Packaged container for ocular perfusion/washing solution and process for producing the same
CN2915109Y (en) * 2006-06-16 2007-06-27 湖南千山制药机械股份有限公司 Hard-mouth infusion bag package provided with protective bag and piercing function-possessed medicine mixing mouth
JP2008029672A (en) * 2006-07-31 2008-02-14 Fuji Seal International Inc Medicine solution bag package
CN101827570A (en) * 2007-10-16 2010-09-08 中央医疗服务有限公司 Double packing materials for infusion solution
CN101461756A (en) * 2007-12-17 2009-06-24 丽珠集团利民制药厂 Medicine liquid flexible package and method for packing the same
CN101874772A (en) * 2010-05-31 2010-11-03 青岛华仁药业股份有限公司 Preparation process for soft bag injection and product
CN102068379A (en) * 2011-01-19 2011-05-25 四川科伦药业股份有限公司 Dual-cavity aseptic bag and manufacturing method thereof
CN102090976A (en) * 2011-01-19 2011-06-15 四川科伦药业股份有限公司 Three-cavity sterile bag and preparation method thereof
CN102488617A (en) * 2011-11-22 2012-06-13 四川科伦药物研究有限公司 Sodium bicarbonate injection plastic soft bag package and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104107140A (en) * 2014-06-23 2014-10-22 武汉药谷生物工程有限公司 Flexible package for injections including sodium bicarbonate
CN105167995A (en) * 2015-08-14 2015-12-23 石家庄四药有限公司 Sodium bicarbonate injection double-layer aseptic vertical bag package system and preparation method thereof
CN105167995B (en) * 2015-08-14 2018-12-25 石家庄四药有限公司 A kind of sodium bicarbonate injection double-layer sterile butt-ended bag packaging system and preparation method
CN107651251A (en) * 2017-08-31 2018-02-02 芜湖杨燕制药有限公司 A kind of insect-expelling saligna injection liquid filling sterilizing technique

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Application publication date: 20131211