JP2007537294A - Ｇａｂａｂレセプターアンタゴニストとアセチルコリンエステラーゼインヒビターとの同時投与により認識機能を改善するための方法 - Google Patents
Ｇａｂａｂレセプターアンタゴニストとアセチルコリンエステラーゼインヒビターとの同時投与により認識機能を改善するための方法 Download PDFInfo
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- JP2007537294A JP2007537294A JP2007513411A JP2007513411A JP2007537294A JP 2007537294 A JP2007537294 A JP 2007537294A JP 2007513411 A JP2007513411 A JP 2007513411A JP 2007513411 A JP2007513411 A JP 2007513411A JP 2007537294 A JP2007537294 A JP 2007537294A
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- gaba
- abpa
- administered
- receptor antagonist
- donepezil
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| JP2007537294A true JP2007537294A (ja) | 2007-12-20 |
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| WO2006091836A1 (en) * | 2005-02-24 | 2006-08-31 | Teva Pharmaceutical Industries, Ltd. | Formulations of ladostigil tartrate |
| US20070135518A1 (en) * | 2005-12-09 | 2007-06-14 | Marta Weinstock-Rosin | Use of low-dose ladostigil for neuroprotection |
| ES2632638T3 (es) * | 2005-12-09 | 2017-09-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Ladostigilo de baja dosis para el tratamiento de la deficiencia cognitiva |
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| US20120225848A1 (en) * | 2009-09-21 | 2012-09-06 | Kleschevnikov Alexander M | Antagonists of GABA-B Receptors to Enhance Neuronal Function, Learning and Memory |
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| AU1153097A (en) * | 1996-06-07 | 1998-01-05 | Eisai Co. Ltd. | Stable polymorphs of donepezil (1-benzyl-4-{(5,6-dimethoxy-1-indanon)-2-yl}methylpiperidine ) hydrochloride and process for production |
| TW513409B (en) * | 1996-06-07 | 2002-12-11 | Eisai Co Ltd | Polymorphs of donepezil hydrochloride |
| US7119189B2 (en) * | 1997-03-19 | 2006-10-10 | Novartis Ag | Metabotropic GABA [B] receptors, receptor-specific ligands and their uses |
| ATE282625T1 (de) * | 1997-06-23 | 2004-12-15 | Polychip Pharmaceuticals Pty | Gaba-c-rezeptor-antagonisten zur stimulation des erinnerungsvermögens |
| US6245911B1 (en) * | 1997-12-05 | 2001-06-12 | Eisai Co., Ltd. | Donepezil polycrystals and process for producing the same |
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| DK1086706T3 (da) * | 1999-03-31 | 2004-03-08 | Eisai Co Ltd | Stabiliserede sammensætninger indeholdende nootropiske lægemidler |
| US20010036949A1 (en) * | 2000-05-09 | 2001-11-01 | Coe Jotham Wadsworth | Pharmaceutical composition and method of treatment of diseases of cognitive dysfunction in a mammal |
| US20020151591A1 (en) * | 2000-10-17 | 2002-10-17 | Anabella Villalobos | Combination use of acetylcholinesterase inhibitors and GABAa inverse agonists for the treatment of cognitive disorders |
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Non-Patent Citations (4)
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| JPN6010061709, ＳＣＡＲＰＩＮＩ，Ｅ． ｅｔ ａｌ, "Ｔｒｅａｔｍｅｎｔ ｏｆ Ａｌｚｈｅｉｍｅｒ’ｓ ｄｉｓｅａｓｅ： ｃｕｒｒｅｎｔ ｓｔａｔｕｓ ａｎｄ ｎｅｗ ｐｅｒｓｐｅｃｔｉｖｅｓ", Ｌａｎｃｅｔ Ｎｅｕｒｏｌ, 2003, Ｖｏｌ．２， Ｎｏ．９, ｐ．５３９−４７ * |
| JPN6010061710, ＹＵ，Ｚ． ｅｔ ａｌ, "Ｍｅｃｈａｎｉｓｍ ｏｆ ｃｏｌｃｈｉｃｉｎｅ ｉｍｐａｉｒｍｅｎｔ ｏｎ ｌｅａｒｎｉｎｇ ａｎｄ ｍｅｍｏｒｙ， ａｎｄ ｐｒｏｔｅｃｔｉｖｅ ｅｆｆｅｃｔ ｏｆ ＣＧＰ ３６７４２ ｉｎ ｍｉｃ", Ｂｒａｉｎ Ｒｅｓｅａｒｃｈ, 1997, Ｖｏｌ．７５０， Ｎｏ．１，２, ｐ．５３−５８ * |
| JPN6010061713, 伊藤芳久, "ＧＡＢＡ受容体とくすり 新しい抗痴呆薬の開発にむけて", 脳２１, 2002, Ｖｏｌ．５，Ｎｏ．１, ｐ．８７−９１ * |
| JPN6010061714, "Ｅｆｆｅｃｔｓ ｏｆ ＧＡＢＡｅｒｇｉｃ ｄｒｕｇｓ ｏｎ ｐｈｙｓｏｓｔｉｇｍｉｎｅ−ｉｎｄｕｃｅｄ ｉｍｐｒｏｖｅｍｅｎｔ ｉｎ ｍｅｍｏｒｙ ａｃｑｕｉｓｉｔｉｏｎ ｏｆ ｐａｓｓｉｖｅ ａｖｏ", Ｇｅｎｅｒａｌ Ｐｈａｒｍａｃｏｌｏｇｙ, 1998, Ｖｏｌ．３１， Ｎｏ．１, ｐ．８１−８６ * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1750724A1 (en) | 2007-02-14 |
| US20050267076A1 (en) | 2005-12-01 |
| EP1750724A4 (en) | 2008-01-23 |
| US20050267077A1 (en) | 2005-12-01 |
| WO2005112946A1 (en) | 2005-12-01 |
| WO2005112908A1 (en) | 2005-12-01 |
| CA2566204A1 (en) | 2005-12-01 |
| AU2005244867A1 (en) | 2005-12-01 |
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