AU2005244867A1 - Method for improving cognitive function by co-administration of a GABAB receptor antagonist and an acetylcholinesterase inhibitor - Google Patents
Method for improving cognitive function by co-administration of a GABAB receptor antagonist and an acetylcholinesterase inhibitor Download PDFInfo
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- AU2005244867A1 AU2005244867A1 AU2005244867A AU2005244867A AU2005244867A1 AU 2005244867 A1 AU2005244867 A1 AU 2005244867A1 AU 2005244867 A AU2005244867 A AU 2005244867A AU 2005244867 A AU2005244867 A AU 2005244867A AU 2005244867 A1 AU2005244867 A1 AU 2005244867A1
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- abpa
- administered
- receptor antagonist
- gabab receptor
- inhibitor
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Classifications
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P25/22—Anxiolytics
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57133004P | 2004-05-14 | 2004-05-14 | |
| US60/571,330 | 2004-05-14 | ||
| PCT/US2005/016805 WO2005112946A1 (en) | 2004-05-14 | 2005-05-13 | Method for improving cognitive function by co-administration of a gabab receptor antagonist and an acetylcholinesterase inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2005244867A1 true AU2005244867A1 (en) | 2005-12-01 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2005244867A Abandoned AU2005244867A1 (en) | 2004-05-14 | 2005-05-13 | Method for improving cognitive function by co-administration of a GABAB receptor antagonist and an acetylcholinesterase inhibitor |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20050267076A1 (https=) |
| EP (1) | EP1750724A4 (https=) |
| JP (1) | JP2007537294A (https=) |
| AU (1) | AU2005244867A1 (https=) |
| CA (1) | CA2566204A1 (https=) |
| WO (2) | WO2005112946A1 (https=) |
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| US20040259844A1 (en) * | 2000-09-22 | 2004-12-23 | Nolan Gerard M. | Method and composition for preventing, reducing and reversing ocular ischemic neuronal damage |
| AU2005244867A1 (en) * | 2004-05-14 | 2005-12-01 | The Johns Hopkins University | Method for improving cognitive function by co-administration of a GABAB receptor antagonist and an acetylcholinesterase inhibitor |
| WO2006091836A1 (en) * | 2005-02-24 | 2006-08-31 | Teva Pharmaceutical Industries, Ltd. | Formulations of ladostigil tartrate |
| US20070135518A1 (en) * | 2005-12-09 | 2007-06-14 | Marta Weinstock-Rosin | Use of low-dose ladostigil for neuroprotection |
| ES2632638T3 (es) * | 2005-12-09 | 2017-09-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Ladostigilo de baja dosis para el tratamiento de la deficiencia cognitiva |
| TW200744576A (en) * | 2006-02-24 | 2007-12-16 | Teva Pharma | Propargylated aminoindans, processes for preparation, and uses thereof |
| US20120225848A1 (en) * | 2009-09-21 | 2012-09-06 | Kleschevnikov Alexander M | Antagonists of GABA-B Receptors to Enhance Neuronal Function, Learning and Memory |
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| US4663318A (en) * | 1986-01-15 | 1987-05-05 | Bonnie Davis | Method of treating Alzheimer's disease |
| FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| GB8728483D0 (en) * | 1987-12-04 | 1988-01-13 | Ciba Geigy Ag | Chemical compounds |
| US5300679A (en) * | 1987-12-04 | 1994-04-05 | Ciba-Geigy Corporation | Substituted propane-phosphinic acid compounds |
| US5750542A (en) * | 1993-09-28 | 1998-05-12 | Pfizer | Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors |
| TW263504B (https=) * | 1991-10-03 | 1995-11-21 | Pfizer | |
| AU662404B2 (en) * | 1992-05-08 | 1995-08-31 | Novartis Ag | Novel N-aralkyl- and N-heteroaralkyl-aminoalkanephosphinic acids |
| AU1153097A (en) * | 1996-06-07 | 1998-01-05 | Eisai Co. Ltd. | Stable polymorphs of donepezil (1-benzyl-4-{(5,6-dimethoxy-1-indanon)-2-yl}methylpiperidine ) hydrochloride and process for production |
| TW513409B (en) * | 1996-06-07 | 2002-12-11 | Eisai Co Ltd | Polymorphs of donepezil hydrochloride |
| US7119189B2 (en) * | 1997-03-19 | 2006-10-10 | Novartis Ag | Metabotropic GABA [B] receptors, receptor-specific ligands and their uses |
| ATE282625T1 (de) * | 1997-06-23 | 2004-12-15 | Polychip Pharmaceuticals Pty | Gaba-c-rezeptor-antagonisten zur stimulation des erinnerungsvermögens |
| US6245911B1 (en) * | 1997-12-05 | 2001-06-12 | Eisai Co., Ltd. | Donepezil polycrystals and process for producing the same |
| GB9805561D0 (en) * | 1998-03-16 | 1998-05-13 | Merck Sharp & Dohme | A combination of therapeutic agents |
| GB9906882D0 (en) * | 1999-03-25 | 1999-05-19 | Novartis Ag | Organic compounds |
| DK1086706T3 (da) * | 1999-03-31 | 2004-03-08 | Eisai Co Ltd | Stabiliserede sammensætninger indeholdende nootropiske lægemidler |
| US20010036949A1 (en) * | 2000-05-09 | 2001-11-01 | Coe Jotham Wadsworth | Pharmaceutical composition and method of treatment of diseases of cognitive dysfunction in a mammal |
| US20020151591A1 (en) * | 2000-10-17 | 2002-10-17 | Anabella Villalobos | Combination use of acetylcholinesterase inhibitors and GABAa inverse agonists for the treatment of cognitive disorders |
| AU2005244867A1 (en) * | 2004-05-14 | 2005-12-01 | The Johns Hopkins University | Method for improving cognitive function by co-administration of a GABAB receptor antagonist and an acetylcholinesterase inhibitor |
-
2005
- 2005-05-13 AU AU2005244867A patent/AU2005244867A1/en not_active Abandoned
- 2005-05-13 WO PCT/US2005/016805 patent/WO2005112946A1/en not_active Ceased
- 2005-05-13 CA CA002566204A patent/CA2566204A1/en not_active Abandoned
- 2005-05-13 WO PCT/US2005/016802 patent/WO2005112908A1/en not_active Ceased
- 2005-05-13 US US11/129,026 patent/US20050267076A1/en not_active Abandoned
- 2005-05-13 EP EP05748406A patent/EP1750724A4/en not_active Withdrawn
- 2005-05-13 US US11/129,027 patent/US20050267077A1/en not_active Abandoned
- 2005-05-13 JP JP2007513411A patent/JP2007537294A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007537294A (ja) | 2007-12-20 |
| EP1750724A1 (en) | 2007-02-14 |
| US20050267076A1 (en) | 2005-12-01 |
| EP1750724A4 (en) | 2008-01-23 |
| US20050267077A1 (en) | 2005-12-01 |
| WO2005112946A1 (en) | 2005-12-01 |
| WO2005112908A1 (en) | 2005-12-01 |
| CA2566204A1 (en) | 2005-12-01 |
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