JP2007536313A - 少なくとも1種の1,4o−結合型サッカロース誘導体を含有する噴霧乾燥粉末及びその製造方法 - Google Patents
少なくとも1種の1,4o−結合型サッカロース誘導体を含有する噴霧乾燥粉末及びその製造方法 Download PDFInfo
- Publication number
- JP2007536313A JP2007536313A JP2007512007A JP2007512007A JP2007536313A JP 2007536313 A JP2007536313 A JP 2007536313A JP 2007512007 A JP2007512007 A JP 2007512007A JP 2007512007 A JP2007512007 A JP 2007512007A JP 2007536313 A JP2007536313 A JP 2007536313A
- Authority
- JP
- Japan
- Prior art keywords
- spray
- powder
- mass
- weight
- dried powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004022926A DE102004022926A1 (de) | 2004-05-10 | 2004-05-10 | Sprühgetrocknete Pulver enthaltend zumindest ein 1,4 O-verknüpftes Saccharose-Derivat und Verfahren zu deren Herstellung |
PCT/EP2005/004806 WO2005112892A1 (fr) | 2004-05-10 | 2005-05-04 | Poudres sechees par pulverisation contenant au moins un derive de saccharose a liaison o en 1,4 et procedes de realisation associes |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2007536313A true JP2007536313A (ja) | 2007-12-13 |
Family
ID=34966513
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007512007A Pending JP2007536313A (ja) | 2004-05-10 | 2005-05-04 | 少なくとも1種の1,4o−結合型サッカロース誘導体を含有する噴霧乾燥粉末及びその製造方法 |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1778188A1 (fr) |
JP (1) | JP2007536313A (fr) |
KR (1) | KR20070037441A (fr) |
CA (1) | CA2564324A1 (fr) |
DE (1) | DE102004022926A1 (fr) |
TW (1) | TW200605917A (fr) |
WO (1) | WO2005112892A1 (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7611709B2 (en) | 2004-05-10 | 2009-11-03 | Boehringer Ingelheim Pharma Gmbh And Co. Kg | 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives |
AU2006328385B2 (en) * | 2005-12-21 | 2011-08-25 | Eisai R & D Management Co., Ltd. | Amorphous form of 1,2-dihydropyridine compound |
EP2077132A1 (fr) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispositif distributeur, dispositif de stockage et procédé pour la distribution d'une formulation |
JP2012509922A (ja) * | 2008-11-27 | 2012-04-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規粉末化結晶質吸入薬 |
EP2414560B1 (fr) | 2009-03-31 | 2013-10-23 | Boehringer Ingelheim International GmbH | Procédé de revêtement d'une surface d'un composant |
WO2010133294A2 (fr) | 2009-05-18 | 2010-11-25 | Boehringer Ingelheim International Gmbh | Adapteur, dispositif d'inhalation et nébuliseur |
JP5658268B2 (ja) | 2009-11-25 | 2015-01-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
CN102686260B (zh) | 2009-11-25 | 2014-10-01 | 贝林格尔.英格海姆国际有限公司 | 喷雾器 |
US9943654B2 (en) | 2010-06-24 | 2018-04-17 | Boehringer Ingelheim International Gmbh | Nebulizer |
WO2012130757A1 (fr) | 2011-04-01 | 2012-10-04 | Boehringer Ingelheim International Gmbh | Appareil médical pourvu d'un récipient |
US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
WO2013152894A1 (fr) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Pulvérisateur comprenant des moyens de détrompage |
US9744313B2 (en) | 2013-08-09 | 2017-08-29 | Boehringer Ingelheim International Gmbh | Nebulizer |
ES2836977T3 (es) | 2013-08-09 | 2021-06-28 | Boehringer Ingelheim Int | Nebulizador |
EP3139979B1 (fr) | 2014-05-07 | 2023-07-05 | Boehringer Ingelheim International GmbH | Unité, nébuliseur et procédé |
UA121114C2 (uk) | 2014-05-07 | 2020-04-10 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | Небулайзер, індикаторний пристрій і контейнер |
ES2874029T3 (es) | 2014-05-07 | 2021-11-04 | Boehringer Ingelheim Int | Nebulizador |
CA2965759C (fr) | 2014-10-31 | 2023-12-12 | Glaxosmithkline Intellectual Property Development Limited | Polypeptides en poudre presentant moins d'impuretes de disulfide comprenant des materiaux cationiques divalents |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0776527A (ja) * | 1993-06-28 | 1995-03-20 | Hayashibara Biochem Lab Inc | 半固形製剤とその製造方法 |
JPH10505591A (ja) * | 1994-08-19 | 1998-06-02 | クアドラント ホールディングス ケンブリッジ リミテッド | 乾燥中および以後の保存中の生物物質の安定化のための改良法とその組成物 |
JP2000510471A (ja) * | 1996-05-08 | 2000-08-15 | インヘイル セラピューティック システムズ | 分散性高分子組成物並びにそれらの調製及び使用のための方法 |
WO2002055101A2 (fr) * | 2000-12-21 | 2002-07-18 | Inhale Therapeutic Syst | Compositions de recepteur de l'interleukine 4 en poudre stables au stockage |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5012272A (fr) * | 1973-06-01 | 1975-02-07 | ||
EP0447125B1 (fr) * | 1990-03-08 | 1995-07-19 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Procédé pour préparer une poudre à contenu élevé de lactosucrose et utilisation de cette poudre |
US6582728B1 (en) * | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
DE69532110T2 (de) * | 1994-01-31 | 2004-09-09 | Yamanouchi Pharmaceutical Co., Ltd. | Intraoral löslicher formpressling und verfahren zu seiner herstellung |
US5922324A (en) * | 1995-01-31 | 1999-07-13 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Propolis extract with improved water-solubility |
US5892026A (en) * | 1995-04-12 | 1999-04-06 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | High Trehalose content syrup |
US6258341B1 (en) * | 1995-04-14 | 2001-07-10 | Inhale Therapeutic Systems, Inc. | Stable glassy state powder formulations |
DE19732351A1 (de) * | 1997-07-28 | 1999-02-04 | Hoechst Ag | Verfahren zur Herstellung der Süßkraft und zur Geschmacksverbesserung einer Mischung hochintensiver Süßstoffe |
-
2004
- 2004-05-10 DE DE102004022926A patent/DE102004022926A1/de not_active Withdrawn
-
2005
- 2005-05-04 CA CA002564324A patent/CA2564324A1/fr not_active Abandoned
- 2005-05-04 JP JP2007512007A patent/JP2007536313A/ja active Pending
- 2005-05-04 WO PCT/EP2005/004806 patent/WO2005112892A1/fr active Application Filing
- 2005-05-04 KR KR1020067025973A patent/KR20070037441A/ko not_active Application Discontinuation
- 2005-05-04 EP EP05738129A patent/EP1778188A1/fr not_active Withdrawn
- 2005-05-09 TW TW094114826A patent/TW200605917A/zh unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0776527A (ja) * | 1993-06-28 | 1995-03-20 | Hayashibara Biochem Lab Inc | 半固形製剤とその製造方法 |
JPH10505591A (ja) * | 1994-08-19 | 1998-06-02 | クアドラント ホールディングス ケンブリッジ リミテッド | 乾燥中および以後の保存中の生物物質の安定化のための改良法とその組成物 |
JP2000510471A (ja) * | 1996-05-08 | 2000-08-15 | インヘイル セラピューティック システムズ | 分散性高分子組成物並びにそれらの調製及び使用のための方法 |
WO2002055101A2 (fr) * | 2000-12-21 | 2002-07-18 | Inhale Therapeutic Syst | Compositions de recepteur de l'interleukine 4 en poudre stables au stockage |
JP2004521103A (ja) * | 2000-12-21 | 2004-07-15 | ネクター セラピューティックス | インターロイキン4レセプターの貯蔵安定性粉末組成物 |
Also Published As
Publication number | Publication date |
---|---|
WO2005112892A1 (fr) | 2005-12-01 |
EP1778188A1 (fr) | 2007-05-02 |
KR20070037441A (ko) | 2007-04-04 |
DE102004022926A1 (de) | 2005-12-15 |
CA2564324A1 (fr) | 2005-12-01 |
TW200605917A (en) | 2006-02-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20101206 |
|
A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20110627 |