MY140680A
(en)
|
2002-05-20 |
2010-01-15 |
Bristol Myers Squibb Co |
Hepatitis c virus inhibitors
|
CA2573271C
(en)
|
2004-07-15 |
2015-10-06 |
Amr Technology, Inc. |
Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
|
US7323447B2
(en)
|
2005-02-08 |
2008-01-29 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
EP1863833B1
(en)
*
|
2005-03-08 |
2013-09-18 |
Boehringer Ingelheim International GmbH |
Process for preparing macrocyclic compounds
|
US7592336B2
(en)
|
2005-05-10 |
2009-09-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7601686B2
(en)
|
2005-07-11 |
2009-10-13 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
TWI387603B
(zh)
|
2005-07-20 |
2013-03-01 |
Merck Sharp & Dohme |
Hcv ns3蛋白酶抑制劑
|
EP2305697A3
(en)
|
2005-07-25 |
2011-07-27 |
Intermune, Inc. |
Macrocyclic inhibitors of Hepatitis C virus replication
|
EP1919898B1
(en)
*
|
2005-07-29 |
2011-01-26 |
Tibotec Pharmaceuticals |
Macrocyclic inhibitors of hepatitis c virus
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
US7772183B2
(en)
|
2005-10-12 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7741281B2
(en)
|
2005-11-03 |
2010-06-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
PT1966130E
(pt)
|
2005-12-23 |
2014-01-30 |
Zealand Pharma As |
Compostos miméticos de lisina modificados
|
US7935670B2
(en)
|
2006-07-11 |
2011-05-03 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
KR101512477B1
(ko)
|
2006-07-13 |
2015-04-15 |
아칠리온 파르마세우티칼스 인코포레이티드 |
바이러스 복제 억제제로서 사용되는 4-아미노-4-옥소부타노일 펩티드
|
US8343477B2
(en)
|
2006-11-01 |
2013-01-01 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus
|
US7772180B2
(en)
|
2006-11-09 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
CN101568543B
(zh)
*
|
2006-11-16 |
2012-06-06 |
百时美施贵宝公司 |
大环肽作为丙型肝炎病毒抑制剂
|
US8003604B2
(en)
|
2006-11-16 |
2011-08-23 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7763584B2
(en)
|
2006-11-16 |
2010-07-27 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7888464B2
(en)
|
2006-11-16 |
2011-02-15 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US20080188545A1
(en)
|
2006-12-21 |
2008-08-07 |
Alimardanov Asaf R |
Synthesis of pyrrolidine compounds
|
AU2008205116A1
(en)
*
|
2007-01-08 |
2008-07-17 |
Phenomix Corporation |
Macrocyclic hepatitis C protease inhibitors
|
WO2008096002A1
(en)
*
|
2007-02-08 |
2008-08-14 |
Tibotec Pharmaceuticals Ltd. |
Hcv inhibiting macrocyclic phosphonates and amidophosphates
|
CA2679377A1
(en)
|
2007-02-26 |
2008-09-04 |
Achillion Pharmaceuticals, Inc. |
Tertiary amine substituted peptides useful as inhibitors of hcv replication
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
US20090155209A1
(en)
*
|
2007-05-03 |
2009-06-18 |
Blatt Lawrence M |
Novel macrocyclic inhibitors of hepatitis c virus replication
|
AP2874A
(en)
|
2007-06-29 |
2014-03-31 |
Gilead Sciences Inc |
Antiviral compounds
|
AU2008271117B2
(en)
|
2007-06-29 |
2013-10-24 |
Gilead Sciences, Inc. |
Antiviral compounds
|
WO2009005690A2
(en)
*
|
2007-06-29 |
2009-01-08 |
Gilead Sciences, Inc. |
Antiviral compounds
|
SE531698C2
(sv)
|
2007-07-12 |
2009-07-07 |
Respiratorius Ab |
Nya bronkdilaterande a,b-omättade amider
|
US8293705B2
(en)
|
2007-12-21 |
2012-10-23 |
Avila Therapeutics, Inc. |
HCV protease inhibitors and uses thereof
|
RU2523790C2
(ru)
|
2007-12-21 |
2014-07-27 |
Авила Терапьютикс, Инк. |
Ингибиторы протеазы вируса гепатита с и их применение
|
RU2515318C2
(ru)
|
2007-12-21 |
2014-05-10 |
Авила Терапьютикс, Инк. |
Ингибиторы протеазы вируса гепатита с и их применение
|
US8309685B2
(en)
|
2007-12-21 |
2012-11-13 |
Celgene Avilomics Research, Inc. |
HCV protease inhibitors and uses thereof
|
US8202996B2
(en)
|
2007-12-21 |
2012-06-19 |
Bristol-Myers Squibb Company |
Crystalline forms of N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-4-((7-chloro-4-methoxy-1-isoquinolinyl)oxy)-N- ((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-L-prolinamide
|
EP2238142B1
(en)
*
|
2007-12-24 |
2012-07-04 |
Janssen R&D Ireland |
Macrocyclic indoles as hepatitis c virus inhibitors
|
PL2276725T3
(pl)
*
|
2008-04-11 |
2012-11-30 |
Hoffmann La Roche |
Nowe kompleksy rutenu jako katalizatory reakcji metatezy
|
US8163921B2
(en)
|
2008-04-16 |
2012-04-24 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7964560B2
(en)
|
2008-05-29 |
2011-06-21 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
EP2300491B1
(en)
|
2008-05-29 |
2016-01-06 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
US9156812B2
(en)
|
2008-06-04 |
2015-10-13 |
Bristol-Myers Squibb Company |
Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
|
WO2010015545A1
(en)
*
|
2008-08-07 |
2010-02-11 |
F. Hoffmann-La Roche Ag |
Process for the preparation of a macrocycle
|
US8207341B2
(en)
|
2008-09-04 |
2012-06-26 |
Bristol-Myers Squibb Company |
Process or synthesizing substituted isoquinolines
|
UY32099A
(es)
|
2008-09-11 |
2010-04-30 |
Enanta Pharm Inc |
Inhibidores macrocíclicos de serina proteasas de hepatitis c
|
BRPI0918653A2
(pt)
|
2008-09-17 |
2015-12-01 |
Boehringer Ingelheim Int |
combinação de inibidor de ns3 protese de hcv com interferon e ribavirina.
|
US8563505B2
(en)
|
2008-09-29 |
2013-10-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US8044087B2
(en)
|
2008-09-29 |
2011-10-25 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
PL2364309T3
(pl)
|
2008-12-10 |
2015-03-31 |
Achillion Pharmaceuticals Inc |
Nowe peptydy 4-amino-4-oksobutanoilowe jako inhibitory wirusowej replikacji
|
US8283310B2
(en)
|
2008-12-15 |
2012-10-09 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
EA019295B1
(ru)
|
2008-12-23 |
2014-02-28 |
Джилид Фармассет, Ллс. |
Соединения пуриновых нуклеозидов и способ их получения
|
EP2376088B1
(en)
|
2008-12-23 |
2017-02-22 |
Gilead Pharmasset LLC |
6-O-Substituted-2-amino-purine nucleoside phosphoramidates
|
US8551973B2
(en)
|
2008-12-23 |
2013-10-08 |
Gilead Pharmasset Llc |
Nucleoside analogs
|
CA2753667C
(en)
|
2009-02-27 |
2015-11-17 |
Ortho-Mcneil-Janssen Pharmaceuticals, Inc. |
Amorphous salt of a macrocyclic inhibitor of hcv
|
WO2010118078A1
(en)
|
2009-04-08 |
2010-10-14 |
Idenix Pharmaceuticals, Inc. |
Macrocyclic serine protease inhibitors
|
EP2429295B1
(en)
|
2009-05-12 |
2013-12-25 |
Albany Molecular Research, Inc. |
Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
|
ES2662072T3
(es)
|
2009-05-12 |
2018-04-05 |
Albany Molecular Research, Inc. |
7-([1,2,4]triazolo[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina y uso de la misma
|
JP5739415B2
(ja)
|
2009-05-12 |
2015-06-24 |
ブリストル−マイヤーズ スクウィブ カンパニー |
(S)−7−([1,2,4]トリアゾロ[1,5−a]ピリジン−6−イル)−4−(3,4−ジクロロフェニル)−1,2,3,4−テトラヒドロイソキノリンの結晶形態およびその使用
|
TWI576352B
(zh)
|
2009-05-20 |
2017-04-01 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
US8232246B2
(en)
|
2009-06-30 |
2012-07-31 |
Abbott Laboratories |
Anti-viral compounds
|
MA33491B1
(fr)
|
2009-07-07 |
2012-08-01 |
Boehringer Ingelheim Int |
Composition pharmaceutique pour un inhibiteur de protease virale de l'hépatite c
|
TW201117812A
(en)
|
2009-08-05 |
2011-06-01 |
Idenix Pharmaceuticals Inc |
Macrocyclic serine protease inhibitors
|
US20110129444A1
(en)
*
|
2009-09-28 |
2011-06-02 |
Intermune, Inc |
Novel macrocyclic inhibitors of hepatitis c virus replication
|
EA201200650A1
(ru)
|
2009-10-30 |
2012-12-28 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Курсы комбинированного лечения вируса гепатита с, включающие bi201335, интерферон-альфа и рибавирин
|
US8933110B2
(en)
|
2010-01-25 |
2015-01-13 |
Enanta Pharmaceuticals, Inc. |
Hepatitis C virus inhibitors
|
CA2787309A1
(en)
|
2010-01-25 |
2011-07-28 |
Enanta Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
EP2609923B1
(en)
|
2010-03-31 |
2017-05-24 |
Gilead Pharmasset LLC |
Process for the crystallisation of (s)-isopropyl 2-(((s)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate
|
JP2013527145A
(ja)
|
2010-03-31 |
2013-06-27 |
ギリード・ファーマセット・エルエルシー |
リン含有活性化剤の立体選択的合成
|
EP2455068A1
(en)
*
|
2010-11-09 |
2012-05-23 |
F. Hoffmann-La Roche AG |
Pharmaceutical composition for treating HCV infections
|
TW201238950A
(en)
|
2010-11-15 |
2012-10-01 |
Abbott Lab |
NAMPT and rock inhibitors
|
AR084044A1
(es)
|
2010-11-30 |
2013-04-17 |
Pharmasset Inc |
Compuestos 2’-espiro-nucleosidos
|
KR20140003521A
(ko)
|
2010-12-30 |
2014-01-09 |
이난타 파마슈티칼스, 인코포레이티드 |
페난트리딘 매크로사이클릭 c형 간염 세린 프로테아제 억제제
|
EP2658859A4
(en)
|
2010-12-30 |
2014-07-30 |
Enanta Pharm Inc |
MACROCYCLIC HEPATITIS C SERIN PROTEASE INHIBITORS
|
AR085352A1
(es)
|
2011-02-10 |
2013-09-25 |
Idenix Pharmaceuticals Inc |
Inhibidores macrociclicos de serina proteasa, sus composiciones farmaceuticas y su uso para tratar infecciones por hcv
|
US8957203B2
(en)
|
2011-05-05 |
2015-02-17 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US10201584B1
(en)
|
2011-05-17 |
2019-02-12 |
Abbvie Inc. |
Compositions and methods for treating HCV
|
US8691757B2
(en)
|
2011-06-15 |
2014-04-08 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
GB201116559D0
(en)
|
2011-09-26 |
2011-11-09 |
Univ Leuven Kath |
Novel viral replication inhibitors
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
EP2858982A4
(en)
|
2012-06-12 |
2015-11-11 |
Abbvie Inc |
PYRIDINONE AND PYRIDAZINONE DERIVATIVES
|
AU2012392557B2
(en)
|
2012-10-19 |
2017-06-01 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US9643999B2
(en)
|
2012-11-02 |
2017-05-09 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
EP2914613B1
(en)
|
2012-11-02 |
2017-11-22 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
US9334279B2
(en)
|
2012-11-02 |
2016-05-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
WO2014070974A1
(en)
|
2012-11-05 |
2014-05-08 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
CN105164148A
(zh)
|
2013-03-07 |
2015-12-16 |
百时美施贵宝公司 |
丙型肝炎病毒抑制剂
|
EP2970195B1
(en)
|
2013-03-14 |
2017-08-02 |
Achillion Pharmaceuticals, Inc. |
Processes for producing sovaprevir
|
US9085607B2
(en)
|
2013-03-15 |
2015-07-21 |
Achillion Pharmaceuticals, Inc. |
ACH-0142684 sodium salt polymorph, composition including the same, and method of manufacture thereof
|
WO2014145507A1
(en)
|
2013-03-15 |
2014-09-18 |
Achillion Pharmaceuticals, Inc. |
A process for making a 4-amino-4-oxobutanoyl peptide cyclic analogue, an inhibitor of viral replication, and intermediates thereof
|
BR112015023351A2
(pt)
|
2013-03-15 |
2017-07-18 |
Achillion Pharmaceuticals Inc |
forma cristalina de sovaprevir, composição farmacêutica, e, método para tratar um distúrbio
|
PL3650014T3
(pl)
|
2013-08-27 |
2022-01-31 |
Gilead Pharmasset Llc |
Preparat złożony dwóch związków przeciwwirusowych
|
WO2015103490A1
(en)
|
2014-01-03 |
2015-07-09 |
Abbvie, Inc. |
Solid antiviral dosage forms
|
DK3618847T3
(da)
|
2017-05-05 |
2021-05-25 |
Boston Medical Ct Corp |
GAP-junction-modulatorer af intercellulær kommunikation og deres anvendelse til behandling af diabetisk øjensygdom
|