JP2007526919A5 - - Google Patents
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- Publication number
- JP2007526919A5 JP2007526919A5 JP2007501755A JP2007501755A JP2007526919A5 JP 2007526919 A5 JP2007526919 A5 JP 2007526919A5 JP 2007501755 A JP2007501755 A JP 2007501755A JP 2007501755 A JP2007501755 A JP 2007501755A JP 2007526919 A5 JP2007526919 A5 JP 2007526919A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- heterologous
- carrier
- linker
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000969 carrier Substances 0.000 claims description 48
- 150000001413 amino acids Chemical class 0.000 claims description 43
- 101700077824 CNN1 Proteins 0.000 claims description 33
- 102100006947 TAGLN Human genes 0.000 claims description 33
- 101710025884 TAGLN Proteins 0.000 claims description 33
- JJAHTWIKCUJRDK-UHFFFAOYSA-N succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate Chemical compound C1CC(CN2C(C=CC2=O)=O)CCC1C(=O)ON1C(=O)CCC1=O JJAHTWIKCUJRDK-UHFFFAOYSA-N 0.000 claims description 33
- 235000001014 amino acid Nutrition 0.000 claims description 28
- 239000004005 microsphere Substances 0.000 claims description 22
- 238000001514 detection method Methods 0.000 claims description 14
- 102000004965 antibodies Human genes 0.000 claims description 11
- 108090001123 antibodies Proteins 0.000 claims description 11
- 235000018102 proteins Nutrition 0.000 claims description 11
- 102000004169 proteins and genes Human genes 0.000 claims description 11
- 108090000623 proteins and genes Proteins 0.000 claims description 11
- 238000000684 flow cytometry Methods 0.000 claims description 9
- 229920000642 polymer Polymers 0.000 claims description 8
- 125000000539 amino acid group Chemical group 0.000 claims description 3
- LQILVUYCDHSGEU-UHFFFAOYSA-N 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexane-1-carboxylic acid Chemical compound C1CC(C(=O)O)CCC1CN1C(=O)C=CC1=O LQILVUYCDHSGEU-UHFFFAOYSA-N 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 30
- 108091003117 Bovine Serum Albumin Proteins 0.000 claims 19
- 125000003275 alpha amino acid group Chemical group 0.000 claims 18
- 229940098773 Bovine Serum Albumin Drugs 0.000 claims 11
- 239000012472 biological sample Substances 0.000 claims 5
- 229920000126 Latex Polymers 0.000 claims 2
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 claims 2
- 125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 claims 2
- 239000004816 latex Substances 0.000 claims 2
- 210000004369 Blood Anatomy 0.000 claims 1
- 210000001175 Cerebrospinal Fluid Anatomy 0.000 claims 1
- 210000003097 Mucus Anatomy 0.000 claims 1
- 210000002381 Plasma Anatomy 0.000 claims 1
- 210000001625 Seminal Vesicles Anatomy 0.000 claims 1
- 210000002966 Serum Anatomy 0.000 claims 1
- LQESELFHCSJUQN-VIFPVBQESA-N [4-[(2S)-2,6-diaminohexanoyl]oxy-3-nitrophenyl]arsonic acid Chemical group NCCCC[C@H](N)C(=O)OC1=CC=C([As](O)(O)=O)C=C1[N+]([O-])=O LQESELFHCSJUQN-VIFPVBQESA-N 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 108010045069 keyhole-limpet hemocyanin Proteins 0.000 claims 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 description 4
- 108090000790 Enzymes Proteins 0.000 description 4
- 239000000427 antigen Substances 0.000 description 4
- 102000038129 antigens Human genes 0.000 description 4
- 108091007172 antigens Proteins 0.000 description 4
- 238000003018 immunoassay Methods 0.000 description 4
- 229910052799 carbon Inorganic materials 0.000 description 3
- 230000001588 bifunctional Effects 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 229960005261 Aspartic Acid Drugs 0.000 description 1
- IRXSLJNXXZKURP-UHFFFAOYSA-N Fluorenylmethyloxycarbonyl chloride Chemical compound C1=CC=C2C(COC(=O)Cl)C3=CC=CC=C3C2=C1 IRXSLJNXXZKURP-UHFFFAOYSA-N 0.000 description 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
- 239000004698 Polyethylene (PE) Substances 0.000 description 1
- 235000003704 aspartic acid Nutrition 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 230000002209 hydrophobic Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000010647 peptide synthesis reaction Methods 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2004/006780 WO2005098051A2 (en) | 2004-03-05 | 2004-03-05 | Hsv-2 type-specific immunoassays using glycoprotein g2 peptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007526919A JP2007526919A (ja) | 2007-09-20 |
| JP2007526919A5 true JP2007526919A5 (no) | 2008-02-14 |
Family
ID=35125690
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007501755A Pending JP2007526919A (ja) | 2004-03-05 | 2004-03-05 | 糖タンパク質ｇ２ペプチドを用いたｈｓｖ−２型特異的免疫検定 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1725687A4 (no) |
| JP (1) | JP2007526919A (no) |
| CN (1) | CN101023187A (no) |
| AU (1) | AU2004318223B8 (no) |
| CA (1) | CA2558246C (no) |
| WO (1) | WO2005098051A2 (no) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5808808B2 (ja) | 2011-06-29 | 2015-11-10 | 株式会社Ｌｓｉメディエンス | 非特異反応抑制剤、非特異反応抑制方法及びキット |
| CN102798709B (zh) * | 2012-08-17 | 2014-11-19 | 深圳市锦瑞电子有限公司 | 一种抗体偶联物及其方法 |
| ES2711177T3 (es) | 2013-12-18 | 2019-04-30 | Board Of Trustees Southern Illinois Univ | Un ensayo serológico rápido y sensible para determinar si los pacientes están infectados por el virus del herpes simple de tipo 1 (VHS-1) y/o de tipo 2 (VHS-2) |
| CN104804068B (zh) * | 2014-01-26 | 2017-12-19 | 中国科学院青岛生物能源与过程研究所 | 一种多肽及其应用和将多肽共价连接到固相界面的方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9615533D0 (en) * | 1996-07-24 | 1996-09-04 | Peptide Therapeutics Ltd | Diagnostic test for herpes simplex virus type-2 |
| GB2323360B (en) * | 1997-01-14 | 1999-06-23 | Medical Res Council | Peptide structures and their use in diagnosis of herpes simplex virus type 2 |
| CA2260991C (en) * | 1997-11-18 | 2009-03-24 | Bio-Rad Laboratories, Inc. | Multiplex flow immunoassays with magnetic particles as solid phase |
| US5919616A (en) * | 1997-12-12 | 1999-07-06 | Aurx, Inc. | Serological assay for herpes |
| JP2002540217A (ja) * | 1999-03-30 | 2002-11-26 | アイデックス ラボラトリーズ インコーポレイテッド | イヌアレルギー用ペプチドワクチン |
| US6821519B2 (en) * | 2000-06-29 | 2004-11-23 | Corixa Corporation | Compositions and methods for the diagnosis and treatment of herpes simplex virus infection |
-
2004
- 2004-03-05 WO PCT/US2004/006780 patent/WO2005098051A2/en active Application Filing
- 2004-03-05 CA CA2558246A patent/CA2558246C/en not_active Expired - Lifetime
- 2004-03-05 AU AU2004318223A patent/AU2004318223B8/en not_active Expired
- 2004-03-05 JP JP2007501755A patent/JP2007526919A/ja active Pending
- 2004-03-05 CN CNA2004800423000A patent/CN101023187A/zh active Pending
- 2004-03-05 EP EP04718011A patent/EP1725687A4/en not_active Ceased
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