JP2007520566A5 - - Google Patents
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- Publication number
- JP2007520566A5 JP2007520566A5 JP2006552302A JP2006552302A JP2007520566A5 JP 2007520566 A5 JP2007520566 A5 JP 2007520566A5 JP 2006552302 A JP2006552302 A JP 2006552302A JP 2006552302 A JP2006552302 A JP 2006552302A JP 2007520566 A5 JP2007520566 A5 JP 2007520566A5
- Authority
- JP
- Japan
- Prior art keywords
- autoantigen
- antibody
- pharmaceutical composition
- antigen
- kit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54195904P | 2004-02-04 | 2004-02-04 | |
| PCT/US2005/003712 WO2005076965A2 (en) | 2004-02-04 | 2005-02-04 | Anti-cd3 and antigen-specific immunotherapy to treat autoimmunity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007520566A JP2007520566A (ja) | 2007-07-26 |
| JP2007520566A5 true JP2007520566A5 (enExample) | 2008-03-27 |
Family
ID=34860238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006552302A Pending JP2007520566A (ja) | 2004-02-04 | 2005-02-04 | 自己免疫治療のための抗cd3及び抗原特異的免疫療法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20070190045A1 (enExample) |
| EP (1) | EP1725254A4 (enExample) |
| JP (1) | JP2007520566A (enExample) |
| AU (1) | AU2005213449A1 (enExample) |
| CA (1) | CA2554978A1 (enExample) |
| IL (1) | IL177193A0 (enExample) |
| WO (1) | WO2005076965A2 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030108548A1 (en) * | 1993-06-01 | 2003-06-12 | Bluestone Jeffrey A. | Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies |
| AU2003300681A1 (en) * | 2002-10-02 | 2004-05-04 | Diamyd Medical Ab | Formulation of glutarmic acid decarboxylase (gad65) and serum albumin |
| CA2569509C (en) | 2004-06-03 | 2014-08-12 | Novimmune S.A. | Anti-cd3 antibodies and methods of use thereof |
| NZ560359A (en) * | 2005-02-04 | 2009-11-27 | Dow Agrosciences Llc | Anti-T cell and autoantigen treatment of autoimmune disease using CD3 monoclonal antibodies and glutamic acid decarboxylase, insulin, beta cell protein or a combination thereof. |
| CA2614640A1 (en) * | 2005-07-11 | 2007-01-18 | Macrogenics, Inc. | Methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity |
| EA014025B1 (ru) * | 2005-09-12 | 2010-08-30 | Новиммун С.А. | Композиции антитела против cd3 |
| US8748126B2 (en) * | 2005-11-29 | 2014-06-10 | Actogenix N.V. | Induction of mucosal tolerance to antigens |
| US20100061984A1 (en) * | 2006-01-20 | 2010-03-11 | The Trustees Of The University Of Pennsylvania | Compositions and methods for modulation of suppressor t cell activation |
| WO2007145941A2 (en) * | 2006-06-06 | 2007-12-21 | Tolerrx, Inc. | Administration of anti-cd3 antibodies in the treatment of autoimmune diseases |
| SG10201504662WA (en) * | 2006-06-14 | 2015-07-30 | Macrogenics Inc | Methods For The Treatment Of Autoimmune Disorders Using Immunosuppressive Monoclonal Antibodies With Reduced Toxicity |
| WO2008079713A2 (en) * | 2006-12-21 | 2008-07-03 | Macrogenics Inc. | Methods for the treatment of lada and other adult-onset autoimmune diabetes using immunosuppressive monoclonal antibodies with reduced toxicity |
| DE102007001370A1 (de) * | 2007-01-09 | 2008-07-10 | Curevac Gmbh | RNA-kodierte Antikörper |
| JP2010516269A (ja) | 2007-01-25 | 2010-05-20 | アクトジェニックス・エヌブイ | 抗原の粘膜送達による免疫疾患の治療 |
| MX2009011481A (es) * | 2007-04-24 | 2010-02-01 | Diamyd Therapeutics Ab | Medicamentos y metodos para tratar enfermedad autoinmune y cancer. |
| WO2011050106A2 (en) * | 2009-10-20 | 2011-04-28 | Tolerx, Inc. | Anti-cd3 antibody dosing in autoimmune disease |
| WO2011091138A1 (en) * | 2010-01-20 | 2011-07-28 | Bayhill Therapeutics, Inc. | Combination therapy to treat autoimmune diseases |
| WO2012012737A2 (en) | 2010-07-23 | 2012-01-26 | The University Of Toledo | Stable tregs and related materials and methods |
| CN103372214B (zh) * | 2012-04-13 | 2017-09-29 | 北京艾棣维欣生物技术有限公司 | 治疗和/或预防ⅰ型糖尿病的药物组合物及其应用 |
| US8735359B2 (en) * | 2012-05-24 | 2014-05-27 | Orban Biotech Llc | Combinations of modalities for the treatment of diabetes |
| SI3151853T1 (sl) * | 2014-06-04 | 2020-10-30 | Diamyd Medical Ab | Dekarboksilaza glutaminske kisline (GAD) za uporabo v zdravljenju avtoimunske bolezni |
| GB201510056D0 (en) * | 2015-06-10 | 2015-07-22 | King S College London | Multi-peptide composition |
| CA3046489A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| US20210138213A1 (en) | 2017-03-30 | 2021-05-13 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| AU2018315052B2 (en) * | 2017-08-07 | 2025-01-02 | St Vincent's Institute Of Medical Research | Type 1 diabetes therapy |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| WO2019246317A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease or condition in a tissue originating from the endoderm |
| CN116726361A (zh) | 2018-11-19 | 2023-09-12 | 比奥拉治疗股份有限公司 | 用生物治疗剂治疗疾病的方法和装置 |
| IL288024B2 (en) | 2019-05-14 | 2025-12-01 | Provention Bio Inc | Methods and compositions for preventing type |
| AU2020398147A1 (en) | 2019-12-06 | 2022-06-02 | Dr. Mary Morris & Associates, Llc | Methods and compositions for the treatment and prevention of Type 1 diabetes |
| WO2021119482A1 (en) | 2019-12-13 | 2021-06-17 | Progenity, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
| US12006366B2 (en) | 2020-06-11 | 2024-06-11 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
| MX2023013851A (es) | 2021-05-24 | 2023-12-08 | Provention Bio Inc | Metodos para el tratamiento de diabetes tipo 1. |
| US12122850B2 (en) | 2022-03-14 | 2024-10-22 | LamKap Bio gamma AG | Bispecific GPC3xCD28 and GPC3xCD3 antibodies and their combination for targeted killing of GPC3 positive malignant cells |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6406696B1 (en) * | 1989-10-27 | 2002-06-18 | Tolerance Therapeutics, Inc. | Methods of stimulating the immune system with anti-CD3 antibodies |
| JP2546544B2 (ja) * | 1989-10-27 | 1996-10-23 | アーチ ディベラップメント コーポレイション | 免疫強化を促進するための方法と組成物 |
| US6150584A (en) * | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5770429A (en) * | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US6491916B1 (en) * | 1994-06-01 | 2002-12-10 | Tolerance Therapeutics, Inc. | Methods and materials for modulation of the immunosuppresive activity and toxicity of monoclonal antibodies |
| US5885573A (en) * | 1993-06-01 | 1999-03-23 | Arch Development Corporation | Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies |
| FR2730411B1 (fr) * | 1995-02-14 | 1997-03-28 | Centre Nat Rech Scient | Association medicamenteuse utile pour la transfection et l'expression in vivo d'exogenes |
| US5834597A (en) * | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
| US6420140B1 (en) * | 1996-10-11 | 2002-07-16 | Abgenix, Inc. | Production of multimeric protein by cell fusion method |
| US6884785B2 (en) * | 1999-06-17 | 2005-04-26 | The Scripps Research Institute | Compositions and methods for the treatment or prevention of autoimmune diabetes |
| US7378089B2 (en) * | 2001-10-02 | 2008-05-27 | The Board Of Trustees Of The Leland Stanford Junior University | Gene therapy for the prevention of autoimmune disease |
| US20040037826A1 (en) * | 2002-06-14 | 2004-02-26 | Michelsen Birgitte Koch | Combined use of a modulator of CD3 and a GLP-1 compound |
-
2005
- 2005-02-04 WO PCT/US2005/003712 patent/WO2005076965A2/en not_active Ceased
- 2005-02-04 JP JP2006552302A patent/JP2007520566A/ja active Pending
- 2005-02-04 AU AU2005213449A patent/AU2005213449A1/en not_active Abandoned
- 2005-02-04 EP EP05722771A patent/EP1725254A4/en not_active Withdrawn
- 2005-02-04 CA CA002554978A patent/CA2554978A1/en not_active Abandoned
-
2006
- 2006-08-01 IL IL177193A patent/IL177193A0/en unknown
- 2006-08-03 US US11/498,381 patent/US20070190045A1/en not_active Abandoned
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