JP2007520566A5 - - Google Patents

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Publication number
JP2007520566A5
JP2007520566A5 JP2006552302A JP2006552302A JP2007520566A5 JP 2007520566 A5 JP2007520566 A5 JP 2007520566A5 JP 2006552302 A JP2006552302 A JP 2006552302A JP 2006552302 A JP2006552302 A JP 2006552302A JP 2007520566 A5 JP2007520566 A5 JP 2007520566A5
Authority
JP
Japan
Prior art keywords
autoantigen
antibody
pharmaceutical composition
antigen
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006552302A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007520566A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/003712 external-priority patent/WO2005076965A2/en
Publication of JP2007520566A publication Critical patent/JP2007520566A/ja
Publication of JP2007520566A5 publication Critical patent/JP2007520566A5/ja
Pending legal-status Critical Current

Links

JP2006552302A 2004-02-04 2005-02-04 自己免疫治療のための抗cd3及び抗原特異的免疫療法 Pending JP2007520566A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54195904P 2004-02-04 2004-02-04
PCT/US2005/003712 WO2005076965A2 (en) 2004-02-04 2005-02-04 Anti-cd3 and antigen-specific immunotherapy to treat autoimmunity

Publications (2)

Publication Number Publication Date
JP2007520566A JP2007520566A (ja) 2007-07-26
JP2007520566A5 true JP2007520566A5 (enExample) 2008-03-27

Family

ID=34860238

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006552302A Pending JP2007520566A (ja) 2004-02-04 2005-02-04 自己免疫治療のための抗cd3及び抗原特異的免疫療法

Country Status (7)

Country Link
US (1) US20070190045A1 (enExample)
EP (1) EP1725254A4 (enExample)
JP (1) JP2007520566A (enExample)
AU (1) AU2005213449A1 (enExample)
CA (1) CA2554978A1 (enExample)
IL (1) IL177193A0 (enExample)
WO (1) WO2005076965A2 (enExample)

Families Citing this family (33)

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Publication number Priority date Publication date Assignee Title
US20030108548A1 (en) * 1993-06-01 2003-06-12 Bluestone Jeffrey A. Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies
AU2003300681A1 (en) * 2002-10-02 2004-05-04 Diamyd Medical Ab Formulation of glutarmic acid decarboxylase (gad65) and serum albumin
CA2569509C (en) 2004-06-03 2014-08-12 Novimmune S.A. Anti-cd3 antibodies and methods of use thereof
NZ560359A (en) * 2005-02-04 2009-11-27 Dow Agrosciences Llc Anti-T cell and autoantigen treatment of autoimmune disease using CD3 monoclonal antibodies and glutamic acid decarboxylase, insulin, beta cell protein or a combination thereof.
CA2614640A1 (en) * 2005-07-11 2007-01-18 Macrogenics, Inc. Methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity
EA014025B1 (ru) * 2005-09-12 2010-08-30 Новиммун С.А. Композиции антитела против cd3
US8748126B2 (en) * 2005-11-29 2014-06-10 Actogenix N.V. Induction of mucosal tolerance to antigens
US20100061984A1 (en) * 2006-01-20 2010-03-11 The Trustees Of The University Of Pennsylvania Compositions and methods for modulation of suppressor t cell activation
WO2007145941A2 (en) * 2006-06-06 2007-12-21 Tolerrx, Inc. Administration of anti-cd3 antibodies in the treatment of autoimmune diseases
SG10201504662WA (en) * 2006-06-14 2015-07-30 Macrogenics Inc Methods For The Treatment Of Autoimmune Disorders Using Immunosuppressive Monoclonal Antibodies With Reduced Toxicity
WO2008079713A2 (en) * 2006-12-21 2008-07-03 Macrogenics Inc. Methods for the treatment of lada and other adult-onset autoimmune diabetes using immunosuppressive monoclonal antibodies with reduced toxicity
DE102007001370A1 (de) * 2007-01-09 2008-07-10 Curevac Gmbh RNA-kodierte Antikörper
JP2010516269A (ja) 2007-01-25 2010-05-20 アクトジェニックス・エヌブイ 抗原の粘膜送達による免疫疾患の治療
MX2009011481A (es) * 2007-04-24 2010-02-01 Diamyd Therapeutics Ab Medicamentos y metodos para tratar enfermedad autoinmune y cancer.
WO2011050106A2 (en) * 2009-10-20 2011-04-28 Tolerx, Inc. Anti-cd3 antibody dosing in autoimmune disease
WO2011091138A1 (en) * 2010-01-20 2011-07-28 Bayhill Therapeutics, Inc. Combination therapy to treat autoimmune diseases
WO2012012737A2 (en) 2010-07-23 2012-01-26 The University Of Toledo Stable tregs and related materials and methods
CN103372214B (zh) * 2012-04-13 2017-09-29 北京艾棣维欣生物技术有限公司 治疗和/或预防ⅰ型糖尿病的药物组合物及其应用
US8735359B2 (en) * 2012-05-24 2014-05-27 Orban Biotech Llc Combinations of modalities for the treatment of diabetes
SI3151853T1 (sl) * 2014-06-04 2020-10-30 Diamyd Medical Ab Dekarboksilaza glutaminske kisline (GAD) za uporabo v zdravljenju avtoimunske bolezni
GB201510056D0 (en) * 2015-06-10 2015-07-22 King S College London Multi-peptide composition
CA3046489A1 (en) 2016-12-07 2018-06-14 Progenity Inc. Gastrointestinal tract detection methods, devices and systems
US20210138213A1 (en) 2017-03-30 2021-05-13 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
AU2018315052B2 (en) * 2017-08-07 2025-01-02 St Vincent's Institute Of Medical Research Type 1 diabetes therapy
WO2019246312A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
WO2019246317A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease or condition in a tissue originating from the endoderm
CN116726361A (zh) 2018-11-19 2023-09-12 比奥拉治疗股份有限公司 用生物治疗剂治疗疾病的方法和装置
IL288024B2 (en) 2019-05-14 2025-12-01 Provention Bio Inc Methods and compositions for preventing type
AU2020398147A1 (en) 2019-12-06 2022-06-02 Dr. Mary Morris & Associates, Llc Methods and compositions for the treatment and prevention of Type 1 diabetes
WO2021119482A1 (en) 2019-12-13 2021-06-17 Progenity, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
US12006366B2 (en) 2020-06-11 2024-06-11 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
MX2023013851A (es) 2021-05-24 2023-12-08 Provention Bio Inc Metodos para el tratamiento de diabetes tipo 1.
US12122850B2 (en) 2022-03-14 2024-10-22 LamKap Bio gamma AG Bispecific GPC3xCD28 and GPC3xCD3 antibodies and their combination for targeted killing of GPC3 positive malignant cells

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6406696B1 (en) * 1989-10-27 2002-06-18 Tolerance Therapeutics, Inc. Methods of stimulating the immune system with anti-CD3 antibodies
JP2546544B2 (ja) * 1989-10-27 1996-10-23 アーチ ディベラップメント コーポレイション 免疫強化を促進するための方法と組成物
US6150584A (en) * 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5770429A (en) * 1990-08-29 1998-06-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US6491916B1 (en) * 1994-06-01 2002-12-10 Tolerance Therapeutics, Inc. Methods and materials for modulation of the immunosuppresive activity and toxicity of monoclonal antibodies
US5885573A (en) * 1993-06-01 1999-03-23 Arch Development Corporation Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies
FR2730411B1 (fr) * 1995-02-14 1997-03-28 Centre Nat Rech Scient Association medicamenteuse utile pour la transfection et l'expression in vivo d'exogenes
US5834597A (en) * 1996-05-20 1998-11-10 Protein Design Labs, Inc. Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same
US6420140B1 (en) * 1996-10-11 2002-07-16 Abgenix, Inc. Production of multimeric protein by cell fusion method
US6884785B2 (en) * 1999-06-17 2005-04-26 The Scripps Research Institute Compositions and methods for the treatment or prevention of autoimmune diabetes
US7378089B2 (en) * 2001-10-02 2008-05-27 The Board Of Trustees Of The Leland Stanford Junior University Gene therapy for the prevention of autoimmune disease
US20040037826A1 (en) * 2002-06-14 2004-02-26 Michelsen Birgitte Koch Combined use of a modulator of CD3 and a GLP-1 compound

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