CA2554978A1 - Anti-cd3 and antigen-specific immunotherapy to treat autoimmunity - Google Patents
Anti-cd3 and antigen-specific immunotherapy to treat autoimmunity Download PDFInfo
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- CA2554978A1 CA2554978A1 CA002554978A CA2554978A CA2554978A1 CA 2554978 A1 CA2554978 A1 CA 2554978A1 CA 002554978 A CA002554978 A CA 002554978A CA 2554978 A CA2554978 A CA 2554978A CA 2554978 A1 CA2554978 A1 CA 2554978A1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54195904P | 2004-02-04 | 2004-02-04 | |
| US60/541,959 | 2004-02-04 | ||
| PCT/US2005/003712 WO2005076965A2 (en) | 2004-02-04 | 2005-02-04 | Anti-cd3 and antigen-specific immunotherapy to treat autoimmunity |
Publications (1)
| Publication Number | Publication Date |
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| CA2554978A1 true CA2554978A1 (en) | 2005-08-25 |
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| CA002554978A Abandoned CA2554978A1 (en) | 2004-02-04 | 2005-02-04 | Anti-cd3 and antigen-specific immunotherapy to treat autoimmunity |
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| CA (1) | CA2554978A1 (enExample) |
| IL (1) | IL177193A0 (enExample) |
| WO (1) | WO2005076965A2 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20030108548A1 (en) * | 1993-06-01 | 2003-06-12 | Bluestone Jeffrey A. | Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies |
| US20050004001A1 (en) * | 2002-10-02 | 2005-01-06 | Robert Harris | Formulation of antigen |
| EP1753783B1 (en) | 2004-06-03 | 2014-08-06 | Novimmune SA | Anti-cd3 antibodies and methods of use thereof |
| JP2008528043A (ja) * | 2005-02-04 | 2008-07-31 | ダウ・アグロサイエンシーズ・エルエルシー | 抗ｔ細胞および自己免疫疾患の自己抗原治療 |
| SG177944A1 (en) * | 2005-07-11 | 2012-02-28 | Macrogenics Inc | Methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity |
| BRPI0615745A2 (pt) * | 2005-09-12 | 2011-05-24 | Novimmune Sa | formulação de anticorpo anti-cd3 |
| ES2596855T3 (es) | 2005-11-29 | 2017-01-12 | Intrexon Actobiotics Nv | Inducción de tolerancia mucosa a antígenos |
| WO2007084775A2 (en) * | 2006-01-20 | 2007-07-26 | The Trustees Of The University Of Pennsylvania | Compositions and methods for modulation of suppressor t cell activation |
| JP2009539841A (ja) * | 2006-06-06 | 2009-11-19 | トラークス，インコーポレイテッド | 自己免疫疾患の治療における抗ｃｄ３抗体の投与 |
| AU2007260687B2 (en) * | 2006-06-14 | 2013-12-12 | Provention Bio, Inc. | Methods for the treatment of autoimmune disorders using monoclonal antibodies with reduced toxicity |
| EP2094302A4 (en) * | 2006-12-21 | 2010-12-08 | Macrogenics Inc | METHODS FOR THE TREATMENT OF LADA-LIKE DIABETES AND OTHER AUTOIMMUNE DIABETES OF THE ADULT USING IMMUNOSUPPRESSANT MONOCLONAL ANTIBODIES HAVING REDUCED TOXICITY |
| DE102007001370A1 (de) * | 2007-01-09 | 2008-07-10 | Curevac Gmbh | RNA-kodierte Antikörper |
| JP2010516269A (ja) | 2007-01-25 | 2010-05-20 | アクトジェニックス・エヌブイ | 抗原の粘膜送達による免疫疾患の治療 |
| RU2009143345A (ru) * | 2007-04-24 | 2011-05-27 | Диамид Терапьютикс Аб (Se) | Лекарственные средства и способы для лечения аутоиммунного заболевания и рака |
| US20120269826A1 (en) * | 2009-10-20 | 2012-10-25 | Mckee Charlotte | Anti-cd3 antibody dosing in autoimmune disease |
| JP2013517329A (ja) * | 2010-01-20 | 2013-05-16 | ベイヒル セラピューティクス インコーポレーティッド | 自己免疫疾患を処置するための併用治療 |
| US9018006B2 (en) | 2010-07-23 | 2015-04-28 | The University Of Toledo | Stable Tregs and related materials and methods |
| CN106668852B (zh) * | 2012-04-13 | 2020-12-25 | 艾棣维欣(苏州)生物制药有限公司 | 一种治疗和/或预防ⅰ型糖尿病的组合物及其应用 |
| US8735359B2 (en) * | 2012-05-24 | 2014-05-27 | Orban Biotech Llc | Combinations of modalities for the treatment of diabetes |
| CN106535926B (zh) * | 2014-06-04 | 2022-02-01 | 戴尔米德医疗公司 | 用于基于抗原的疗法的新型组合物 |
| GB201510056D0 (en) * | 2015-06-10 | 2015-07-22 | King S College London | Multi-peptide composition |
| EP3551034A1 (en) | 2016-12-07 | 2019-10-16 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| EP4108183A1 (en) | 2017-03-30 | 2022-12-28 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| AU2018315052B2 (en) * | 2017-08-07 | 2025-01-02 | St Vincent's Institute Of Medical Research | Type 1 diabetes therapy |
| US12227565B2 (en) | 2018-06-20 | 2025-02-18 | Biora Therapeutics, Inc. | Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| WO2020106704A2 (en) | 2018-11-19 | 2020-05-28 | Progenity, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
| IL322315A (en) | 2019-05-14 | 2025-09-01 | Provention Bio Inc | Methods and preparations for preventing type 1 diabetes |
| CN121197633A (zh) | 2019-12-13 | 2025-12-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| MX2022015872A (es) | 2020-06-11 | 2023-05-16 | Provention Bio Inc | Metodos y composiciones para prevenir diabetes tipo 1. |
| WO2023174925A1 (en) | 2022-03-14 | 2023-09-21 | Novimmune Sa | Bispecific gpc3xcd28 and gpc3xcd3 antibodies and their combination for targeted killing of gpc3 positive malignant cells |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0497883B1 (en) * | 1989-10-27 | 1998-07-15 | Arch Development Corporation | Compositions and their use for promoting immunopotentiation |
| US6406696B1 (en) * | 1989-10-27 | 2002-06-18 | Tolerance Therapeutics, Inc. | Methods of stimulating the immune system with anti-CD3 antibodies |
| US6150584A (en) * | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5770429A (en) * | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5885573A (en) * | 1993-06-01 | 1999-03-23 | Arch Development Corporation | Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies |
| US6491916B1 (en) * | 1994-06-01 | 2002-12-10 | Tolerance Therapeutics, Inc. | Methods and materials for modulation of the immunosuppresive activity and toxicity of monoclonal antibodies |
| FR2730411B1 (fr) * | 1995-02-14 | 1997-03-28 | Centre Nat Rech Scient | Association medicamenteuse utile pour la transfection et l'expression in vivo d'exogenes |
| US5834597A (en) * | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
| US6420140B1 (en) * | 1996-10-11 | 2002-07-16 | Abgenix, Inc. | Production of multimeric protein by cell fusion method |
| US6884785B2 (en) * | 1999-06-17 | 2005-04-26 | The Scripps Research Institute | Compositions and methods for the treatment or prevention of autoimmune diabetes |
| US7378089B2 (en) * | 2001-10-02 | 2008-05-27 | The Board Of Trustees Of The Leland Stanford Junior University | Gene therapy for the prevention of autoimmune disease |
| US20040037826A1 (en) * | 2002-06-14 | 2004-02-26 | Michelsen Birgitte Koch | Combined use of a modulator of CD3 and a GLP-1 compound |
-
2005
- 2005-02-04 AU AU2005213449A patent/AU2005213449A1/en not_active Abandoned
- 2005-02-04 JP JP2006552302A patent/JP2007520566A/ja active Pending
- 2005-02-04 EP EP05722771A patent/EP1725254A4/en not_active Withdrawn
- 2005-02-04 WO PCT/US2005/003712 patent/WO2005076965A2/en not_active Ceased
- 2005-02-04 CA CA002554978A patent/CA2554978A1/en not_active Abandoned
-
2006
- 2006-08-01 IL IL177193A patent/IL177193A0/en unknown
- 2006-08-03 US US11/498,381 patent/US20070190045A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1725254A4 (en) | 2008-02-13 |
| WO2005076965A3 (en) | 2006-07-06 |
| WO2005076965A2 (en) | 2005-08-25 |
| JP2007520566A (ja) | 2007-07-26 |
| EP1725254A2 (en) | 2006-11-29 |
| AU2005213449A1 (en) | 2005-08-25 |
| IL177193A0 (en) | 2006-12-10 |
| US20070190045A1 (en) | 2007-08-16 |
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