AU2005213449A1 - Anti-CD3 and antigen-specific immunotherapy to treat autoimmunity - Google Patents
Anti-CD3 and antigen-specific immunotherapy to treat autoimmunity Download PDFInfo
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- AU2005213449A1 AU2005213449A1 AU2005213449A AU2005213449A AU2005213449A1 AU 2005213449 A1 AU2005213449 A1 AU 2005213449A1 AU 2005213449 A AU2005213449 A AU 2005213449A AU 2005213449 A AU2005213449 A AU 2005213449A AU 2005213449 A1 AU2005213449 A1 AU 2005213449A1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54195904P | 2004-02-04 | 2004-02-04 | |
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| PCT/US2005/003712 WO2005076965A2 (en) | 2004-02-04 | 2005-02-04 | Anti-cd3 and antigen-specific immunotherapy to treat autoimmunity |
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| US20030108548A1 (en) * | 1993-06-01 | 2003-06-12 | Bluestone Jeffrey A. | Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies |
| WO2004035084A2 (en) * | 2002-10-02 | 2004-04-29 | Diamyd Medical Ab | Formulation of glutarmic acid decarboxylase (gad65) and serum albumin |
| EA010350B1 (ru) * | 2004-06-03 | 2008-08-29 | Новиммун С.А. | Антитела против cd3 и способы их применения |
| NZ560359A (en) * | 2005-02-04 | 2009-11-27 | Dow Agrosciences Llc | Anti-T cell and autoantigen treatment of autoimmune disease using CD3 monoclonal antibodies and glutamic acid decarboxylase, insulin, beta cell protein or a combination thereof. |
| US8663634B2 (en) * | 2005-07-11 | 2014-03-04 | Macrogenics, Inc. | Methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity |
| AU2006291005A1 (en) * | 2005-09-12 | 2007-03-22 | Novimmune S.A. | Anti-CD3 antibody formulations |
| PT2119450E (pt) * | 2005-11-29 | 2013-04-26 | Actogenix Nv | Indução de tolerância da mucosa a autoantigénios de células beta de ilhéus pancreáticos |
| US20100061984A1 (en) * | 2006-01-20 | 2010-03-11 | The Trustees Of The University Of Pennsylvania | Compositions and methods for modulation of suppressor t cell activation |
| CA2653387A1 (en) * | 2006-06-06 | 2007-12-21 | Tolerrx, Inc. | Administration of anti-cd3 antibodies in the treatment of autoimmune diseases |
| BRPI0713426A2 (pt) * | 2006-06-14 | 2012-10-09 | Macrogenics Inc | métodos de tratar, diminuir a progressão, ou melhorar um ou mais sintomas de um distúrbio, e de prevenir ou retardar o inìcio de um distúrbio |
| WO2008079713A2 (en) * | 2006-12-21 | 2008-07-03 | Macrogenics Inc. | Methods for the treatment of lada and other adult-onset autoimmune diabetes using immunosuppressive monoclonal antibodies with reduced toxicity |
| DE102007001370A1 (de) * | 2007-01-09 | 2008-07-10 | Curevac Gmbh | RNA-kodierte Antikörper |
| ES2666658T3 (es) | 2007-01-25 | 2018-05-07 | Intrexon Actobiotics Nv | Tratamiento de enfermedad inmune mediante suministro a la mucosa de antígenos |
| US20090092637A1 (en) * | 2007-04-24 | 2009-04-09 | Diamyd Therapeutics Ab | Medicaments and methods to treat autoimmune disease and cancer |
| CA2778334A1 (en) * | 2009-10-20 | 2011-04-28 | Charlotte Mckee | Anti-cd3 antibody dosing in autoimmune disease |
| EP2525825A1 (en) * | 2010-01-20 | 2012-11-28 | Bayhill Therapeutics, Inc. | Combination therapy to treat autoimmune diseases |
| US9018006B2 (en) | 2010-07-23 | 2015-04-28 | The University Of Toledo | Stable Tregs and related materials and methods |
| CN106668852B (zh) * | 2012-04-13 | 2020-12-25 | 艾棣维欣(苏州)生物制药有限公司 | 一种治疗和/或预防ⅰ型糖尿病的组合物及其应用 |
| US8735359B2 (en) * | 2012-05-24 | 2014-05-27 | Orban Biotech Llc | Combinations of modalities for the treatment of diabetes |
| SMT202000384T1 (it) * | 2014-06-04 | 2020-09-10 | Diamyd Medical Ab | Acido glutammico decarbossilasi(gad)per l'uso nel trattamento di una malattia autoimmune |
| GB201510056D0 (en) * | 2015-06-10 | 2015-07-22 | King S College London | Multi-peptide composition |
| WO2018106931A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| CA3054632A1 (en) | 2017-03-30 | 2018-10-04 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| WO2019028503A1 (en) * | 2017-08-07 | 2019-02-14 | St Vincent's Institute Of Medical Research | THERAPY OF DIABETES TYPE 1 |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| US12227565B2 (en) | 2018-06-20 | 2025-02-18 | Biora Therapeutics, Inc. | Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine |
| CN116726361A (zh) | 2018-11-19 | 2023-09-12 | 比奥拉治疗股份有限公司 | 用生物治疗剂治疗疾病的方法和装置 |
| KR20230031981A (ko) | 2019-05-14 | 2023-03-07 | 프로벤션 바이오, 인코포레이티드 | 제1형 당뇨병을 예방하기 위한 방법 및 조성물 |
| US11707610B2 (en) | 2019-12-13 | 2023-07-25 | Biora Therapeutics, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
| IL298999A (en) | 2020-06-11 | 2023-02-01 | Provention Bio Inc | Methods and compositions for the prevention of type 1 diabetes |
| EP4493592A1 (en) | 2022-03-14 | 2025-01-22 | LamKap Bio gamma AG | Bispecific gpc3xcd28 and gpc3xcd3 antibodies and their combination for targeted killing of gpc3 positive malignant cells |
Family Cites Families (12)
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| WO1991006319A1 (en) * | 1989-10-27 | 1991-05-16 | Arch Development Corporation | Methods and compositions for promoting immunopotentiation |
| US6406696B1 (en) * | 1989-10-27 | 2002-06-18 | Tolerance Therapeutics, Inc. | Methods of stimulating the immune system with anti-CD3 antibodies |
| US6150584A (en) * | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5770429A (en) * | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US6491916B1 (en) * | 1994-06-01 | 2002-12-10 | Tolerance Therapeutics, Inc. | Methods and materials for modulation of the immunosuppresive activity and toxicity of monoclonal antibodies |
| US5885573A (en) * | 1993-06-01 | 1999-03-23 | Arch Development Corporation | Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies |
| FR2730411B1 (fr) * | 1995-02-14 | 1997-03-28 | Centre Nat Rech Scient | Association medicamenteuse utile pour la transfection et l'expression in vivo d'exogenes |
| US5834597A (en) * | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
| US6420140B1 (en) * | 1996-10-11 | 2002-07-16 | Abgenix, Inc. | Production of multimeric protein by cell fusion method |
| US6884785B2 (en) * | 1999-06-17 | 2005-04-26 | The Scripps Research Institute | Compositions and methods for the treatment or prevention of autoimmune diabetes |
| US7378089B2 (en) * | 2001-10-02 | 2008-05-27 | The Board Of Trustees Of The Leland Stanford Junior University | Gene therapy for the prevention of autoimmune disease |
| US20040037826A1 (en) * | 2002-06-14 | 2004-02-26 | Michelsen Birgitte Koch | Combined use of a modulator of CD3 and a GLP-1 compound |
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- 2005-02-04 EP EP05722771A patent/EP1725254A4/en not_active Withdrawn
- 2005-02-04 CA CA002554978A patent/CA2554978A1/en not_active Abandoned
- 2005-02-04 WO PCT/US2005/003712 patent/WO2005076965A2/en not_active Ceased
- 2005-02-04 AU AU2005213449A patent/AU2005213449A1/en not_active Abandoned
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- 2006-08-03 US US11/498,381 patent/US20070190045A1/en not_active Abandoned
Also Published As
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|---|---|
| US20070190045A1 (en) | 2007-08-16 |
| JP2007520566A (ja) | 2007-07-26 |
| EP1725254A4 (en) | 2008-02-13 |
| IL177193A0 (en) | 2006-12-10 |
| EP1725254A2 (en) | 2006-11-29 |
| CA2554978A1 (en) | 2005-08-25 |
| WO2005076965A2 (en) | 2005-08-25 |
| WO2005076965A3 (en) | 2006-07-06 |
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