JP2007520565A5 - - Google Patents
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- Publication number
- JP2007520565A5 JP2007520565A5 JP2006552282A JP2006552282A JP2007520565A5 JP 2007520565 A5 JP2007520565 A5 JP 2007520565A5 JP 2006552282 A JP2006552282 A JP 2006552282A JP 2006552282 A JP2006552282 A JP 2006552282A JP 2007520565 A5 JP2007520565 A5 JP 2007520565A5
- Authority
- JP
- Japan
- Prior art keywords
- animal
- human
- pharmaceutical composition
- pharmaceutical
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 0 CC(*(C)I)C=C(C(N(**)C1=C)=C)N(C)C1=I Chemical compound CC(*(C)I)C=C(C(N(**)C1=C)=C)N(C)C1=I 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54207304P | 2004-02-04 | 2004-02-04 | |
| US62426204P | 2004-11-01 | 2004-11-01 | |
| PCT/US2005/003636 WO2005077940A1 (fr) | 2004-02-04 | 2005-02-04 | Dehydrophenylahistines et leurs analogues et la synthese des dehydrophenylahistines et de leurs analogues |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007520565A JP2007520565A (ja) | 2007-07-26 |
| JP2007520565A5 true JP2007520565A5 (fr) | 2008-04-03 |
Family
ID=34864489
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006552282A Pending JP2007520565A (ja) | 2004-02-04 | 2005-02-04 | デヒドロフェニラヒスチン及びそれらの類似体、並びにデヒドロフェニラヒスチン及びそれらの類似体の合成 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1711487A1 (fr) |
| JP (1) | JP2007520565A (fr) |
| KR (1) | KR101228104B1 (fr) |
| AU (1) | AU2005212399B2 (fr) |
| BR (1) | BRPI0506655A (fr) |
| CA (1) | CA2553630A1 (fr) |
| IL (1) | IL176932A0 (fr) |
| NZ (1) | NZ548659A (fr) |
| WO (1) | WO2005077940A1 (fr) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101049100B1 (ko) | 2002-08-02 | 2011-07-15 | 니리어스 파마슈티컬즈, 인코퍼레이션 | 데하이드로페닐아히스틴 및 그의 동족체, 및 이들의 합성방법 |
| US7919497B2 (en) | 2002-08-02 | 2011-04-05 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| US7935704B2 (en) | 2003-08-01 | 2011-05-03 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
| EP1926724A1 (fr) * | 2005-09-21 | 2008-06-04 | Nereus Pharmaceuticals, Inc. | Analogues de deshydrophenylahistines et utilisation therapeutique de ceux-ci |
| US8129527B2 (en) | 2006-11-03 | 2012-03-06 | Nereus Pharmacuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| CN105705148B (zh) * | 2013-10-11 | 2021-03-23 | 大连万春布林医药有限公司 | 使用普那布林和紫杉烷的组合的癌症疗法 |
| EP3256130A4 (fr) * | 2015-02-12 | 2018-08-01 | Beyondspring Pharmaceuticals, Inc. | Utilisation de plinabuline en combinaison avec des inhibiteurs du point de contrôle immunitaire |
| CA2978679A1 (fr) | 2015-03-06 | 2016-09-15 | Beyondspring Pharmaceuticals, Inc. | Methode de traitement d'une tumeur cerebrale |
| US10238650B2 (en) | 2015-03-06 | 2019-03-26 | Beyondspring Pharmaceuticals, Inc. | Method of treating cancer associated with a RAS mutation |
| WO2017011399A1 (fr) * | 2015-07-13 | 2017-01-19 | Beyondspring Pharmaceuticals, Inc | Compositions de plinabuline |
| IL260933B2 (en) | 2016-02-08 | 2023-04-01 | Beyondspring Pharmaceuticals Inc | Preparations containing tocorsol or its analogues |
| EP3463337A4 (fr) | 2016-06-06 | 2020-02-12 | Beyondspring Pharmaceuticals, Inc. | Composition et méthode permettant de réduire la neutropénie |
| CN109563079B (zh) | 2016-08-12 | 2021-10-26 | 深圳华大海洋科技有限公司 | 脱氢苯基阿夕斯丁类化合物的多晶型及其制备纯化方法和应用 |
| CN110431135A (zh) | 2017-01-06 | 2019-11-08 | 大连万春布林医药有限公司 | 微管蛋白结合化合物及其治疗用途 |
| CA3052190A1 (fr) | 2017-02-01 | 2018-08-09 | Beyondspring Pharmaceuticals, Inc. | Methode de reduction de la neutropenie |
| SG11201908420WA (en) * | 2017-03-13 | 2019-10-30 | Beyondspring Pharmaceuticals Inc | Compositions of plinabulin and use thereof |
| BR112020014960A2 (pt) | 2018-01-24 | 2020-12-22 | Beyondspring Pharmaceuticals, Inc. | Composição e método para redução de trombocitopenia |
| CN108524442B (zh) * | 2018-06-05 | 2022-01-28 | 深圳海王医药科技研究院有限公司 | 一种抗肿瘤药物的注射剂及其制备方法 |
| JP2018199726A (ja) * | 2018-09-26 | 2018-12-20 | ビヨンドスプリング インコーポレイテッド | プリナブリン及びタキサンの組合せがん治療 |
| WO2023060200A1 (fr) * | 2021-10-07 | 2023-04-13 | Beyondspring Pharmaceuticals, Inc. | Méthodes de traitement de cancers et de tumeurs |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3318789A1 (de) * | 1983-05-24 | 1984-11-29 | Eduard Gerlach GmbH Chemische Fabrik, 4990 Lübbecke | Deodorant |
| GB9402807D0 (en) * | 1994-02-14 | 1994-04-06 | Xenova Ltd | Pharmaceutical compounds |
| US6069146A (en) * | 1998-03-25 | 2000-05-30 | The Regents Of The University Of California | Halimide, a cytotoxic marine natural product, and derivatives thereof |
| US6358957B1 (en) * | 1998-11-12 | 2002-03-19 | Nereus Pharmaceuticals, Inc. | Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds |
| BRPI0017067B8 (pt) * | 2000-01-18 | 2021-05-25 | Beyondspring Pharmaceuticals Inc | inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto |
| KR100852965B1 (ko) * | 2000-05-09 | 2008-08-19 | 애드파르마 인코포레이티드 | 피페라진디온 화합물 |
| KR101049100B1 (ko) * | 2002-08-02 | 2011-07-15 | 니리어스 파마슈티컬즈, 인코퍼레이션 | 데하이드로페닐아히스틴 및 그의 동족체, 및 이들의 합성방법 |
-
2005
- 2005-02-04 KR KR1020067017883A patent/KR101228104B1/ko active IP Right Grant
- 2005-02-04 WO PCT/US2005/003636 patent/WO2005077940A1/fr active Application Filing
- 2005-02-04 EP EP05712910A patent/EP1711487A1/fr not_active Withdrawn
- 2005-02-04 NZ NZ548659A patent/NZ548659A/en unknown
- 2005-02-04 BR BRPI0506655-7A patent/BRPI0506655A/pt not_active IP Right Cessation
- 2005-02-04 CA CA002553630A patent/CA2553630A1/fr not_active Abandoned
- 2005-02-04 AU AU2005212399A patent/AU2005212399B2/en not_active Ceased
- 2005-02-04 JP JP2006552282A patent/JP2007520565A/ja active Pending
-
2006
- 2006-07-18 IL IL176932A patent/IL176932A0/en unknown
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