JP2007520565A5 - - Google Patents
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- Publication number
- JP2007520565A5 JP2007520565A5 JP2006552282A JP2006552282A JP2007520565A5 JP 2007520565 A5 JP2007520565 A5 JP 2007520565A5 JP 2006552282 A JP2006552282 A JP 2006552282A JP 2006552282 A JP2006552282 A JP 2006552282A JP 2007520565 A5 JP2007520565 A5 JP 2007520565A5
- Authority
- JP
- Japan
- Prior art keywords
- animal
- human
- pharmaceutical composition
- pharmaceutical
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 0 CC(*(C)I)C=C(C(N(**)C1=C)=C)N(C)C1=I Chemical compound CC(*(C)I)C=C(C(N(**)C1=C)=C)N(C)C1=I 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| US54207304P | 2004-02-04 | 2004-02-04 | |
| US62426204P | 2004-11-01 | 2004-11-01 | |
| PCT/US2005/003636 WO2005077940A1 (en) | 2004-02-04 | 2005-02-04 | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof | 
Publications (2)
| Publication Number | Publication Date | 
|---|---|
| JP2007520565A JP2007520565A (ja) | 2007-07-26 | 
| JP2007520565A5 true JP2007520565A5 (enrdf_load_html_response) | 2008-04-03 | 
Family
ID=34864489
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| JP2006552282A Pending JP2007520565A (ja) | 2004-02-04 | 2005-02-04 | デヒドロフェニラヒスチン及びそれらの類似体、並びにデヒドロフェニラヒスチン及びそれらの類似体の合成 | 
Country Status (9)
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| ES2295695T3 (es) | 2002-08-02 | 2008-04-16 | Nereus Pharmaceuticals, Inc. | Deshidrofenilahistinas y sus analogos y la sintesis de deshidrofenilahistinas y sus analogos. | 
| US7919497B2 (en) | 2002-08-02 | 2011-04-05 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use | 
| US7935704B2 (en) | 2003-08-01 | 2011-05-03 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof | 
| EP1926724A1 (en) * | 2005-09-21 | 2008-06-04 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use | 
| US8129527B2 (en) | 2006-11-03 | 2012-03-06 | Nereus Pharmacuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use | 
| MX384751B (es) | 2013-10-11 | 2025-03-14 | Beyondspring Inc | Tratamiento del cáncer con una combinación de plinabulina y taxano. | 
| MX394865B (es) * | 2015-02-12 | 2025-03-24 | Beyondspring Pharmaceuticals Inc | Uso de plinabulina en combinación con inhibidores de punto de control inmunitario | 
| CA2978679A1 (en) | 2015-03-06 | 2016-09-15 | Beyondspring Pharmaceuticals, Inc. | Method of treating a brain tumor | 
| SG11201707127VA (en) | 2015-03-06 | 2017-09-28 | Beyondspring Pharmaceuticals Inc | Method of treating cancer associated with a ras mutation | 
| SG10202108194XA (en) * | 2015-07-13 | 2021-09-29 | Beyondspring Pharmaceuticals Inc | Plinabulin compositions | 
| RU2753543C1 (ru) | 2016-02-08 | 2021-08-17 | Бейондспринг Фармасьютикалс, Инк. | Композиции, содержащие тукаресол или его аналоги | 
| CN118304304A (zh) | 2016-06-06 | 2024-07-09 | 大连万春布林医药有限公司 | 用于减少中性粒细胞减少症的组合物和方法 | 
| EP4089085B1 (en) * | 2016-08-12 | 2024-04-03 | Shenzhen Huahong Marine Biomedicine Co., Ltd | Manufacturing and purification method of polycrystalline form of dehydrophenylahistin-like compound | 
| EP3565812B1 (en) | 2017-01-06 | 2023-12-27 | Beyondspring Pharmaceuticals, Inc. | Tubulin binding compounds and therapeutic use thereof | 
| CN110381938A (zh) | 2017-02-01 | 2019-10-25 | 大连万春布林医药有限公司 | 减少中性粒细胞缺乏症的方法 | 
| CN110603037A (zh) * | 2017-03-13 | 2019-12-20 | 大连万春布林医药有限公司 | 普那布林的组合物及其用途 | 
| US11786523B2 (en) | 2018-01-24 | 2023-10-17 | Beyondspring Pharmaceuticals, Inc. | Composition and method for reducing thrombocytopenia | 
| CN108524442B (zh) * | 2018-06-05 | 2022-01-28 | 深圳海王医药科技研究院有限公司 | 一种抗肿瘤药物的注射剂及其制备方法 | 
| JP2018199726A (ja) * | 2018-09-26 | 2018-12-20 | ビヨンドスプリング インコーポレイテッド | プリナブリン及びタキサンの組合せがん治療 | 
| US20240197723A1 (en) | 2021-04-09 | 2024-06-20 | Beyondspring Pharmaceuticals, Inc. | Therapeutic compositions and methods for treating tumors | 
| JP2024538730A (ja) * | 2021-10-07 | 2024-10-23 | ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド | がん及び腫瘍を治療するための方法 | 
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| DE3318789C2 (de) * | 1983-05-24 | 1987-04-02 | Eduard Gerlach GmbH Chemische Fabrik, 4990 Lübbecke | Deodorant | 
| GB9402807D0 (en) * | 1994-02-14 | 1994-04-06 | Xenova Ltd | Pharmaceutical compounds | 
| US6069146A (en) * | 1998-03-25 | 2000-05-30 | The Regents Of The University Of California | Halimide, a cytotoxic marine natural product, and derivatives thereof | 
| US6358957B1 (en) * | 1998-11-12 | 2002-03-19 | Nereus Pharmaceuticals, Inc. | Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds | 
| BRPI0017067B8 (pt) * | 2000-01-18 | 2021-05-25 | Beyondspring Pharmaceuticals Inc | inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto | 
| HUP0302358A3 (en) * | 2000-05-09 | 2007-09-28 | Adpharma | Piperazinedione compounds and use of them for producing pharmaceutical compositions | 
| ES2295695T3 (es) * | 2002-08-02 | 2008-04-16 | Nereus Pharmaceuticals, Inc. | Deshidrofenilahistinas y sus analogos y la sintesis de deshidrofenilahistinas y sus analogos. | 
- 
        2005
        - 2005-02-04 EP EP05712910A patent/EP1711487A1/en not_active Withdrawn
- 2005-02-04 AU AU2005212399A patent/AU2005212399B2/en not_active Ceased
- 2005-02-04 BR BRPI0506655-7A patent/BRPI0506655A/pt not_active IP Right Cessation
- 2005-02-04 CA CA002553630A patent/CA2553630A1/en not_active Abandoned
- 2005-02-04 NZ NZ548659A patent/NZ548659A/en not_active IP Right Cessation
- 2005-02-04 JP JP2006552282A patent/JP2007520565A/ja active Pending
- 2005-02-04 KR KR1020067017883A patent/KR101228104B1/ko not_active Expired - Lifetime
- 2005-02-04 WO PCT/US2005/003636 patent/WO2005077940A1/en active Application Filing
 
- 
        2006
        - 2006-07-18 IL IL176932A patent/IL176932A0/en unknown