JP2007520349A - 計量ポンプシステム - Google Patents
計量ポンプシステム Download PDFInfo
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- JP2007520349A JP2007520349A JP2006551928A JP2006551928A JP2007520349A JP 2007520349 A JP2007520349 A JP 2007520349A JP 2006551928 A JP2006551928 A JP 2006551928A JP 2006551928 A JP2006551928 A JP 2006551928A JP 2007520349 A JP2007520349 A JP 2007520349A
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Images
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1042—Components or details
- B05B11/1052—Actuation means
- B05B11/1056—Actuation means comprising rotatable or articulated levers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/08—Inhaling devices inserted into the nose
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1042—Components or details
- B05B11/1066—Pump inlet valves
- B05B11/1067—Pump inlet valves actuated by pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1042—Components or details
- B05B11/1066—Pump inlet valves
- B05B11/107—Gate valves; Sliding valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/109—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
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- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1095—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle with movable suction side
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/0005—Components or details
- B05B11/0037—Containers
- B05B11/0038—Inner container disposed in an outer shell or outer casing
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Loading And Unloading Of Fuel Tanks Or Ships (AREA)
- Reciprocating Pumps (AREA)
- Devices For Dispensing Beverages (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0402695.1A GB0402695D0 (en) | 2004-02-06 | 2004-02-06 | A metering pump system |
| PCT/GB2005/000416 WO2005075105A1 (en) | 2004-02-06 | 2005-02-04 | A metering pump system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007520349A true JP2007520349A (ja) | 2007-07-26 |
| JP2007520349A5 JP2007520349A5 (enExample) | 2008-03-13 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551928A Pending JP2007520349A (ja) | 2004-02-06 | 2005-02-04 | 計量ポンプシステム |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20070095853A1 (enExample) |
| EP (1) | EP1711276A1 (enExample) |
| JP (1) | JP2007520349A (enExample) |
| CN (1) | CN100594071C (enExample) |
| AU (1) | AU2005210216A1 (enExample) |
| BR (1) | BRPI0507396A (enExample) |
| CA (1) | CA2555298A1 (enExample) |
| GB (1) | GB0402695D0 (enExample) |
| WO (1) | WO2005075105A1 (enExample) |
| ZA (1) | ZA200606463B (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011508613A (ja) * | 2007-11-29 | 2011-03-17 | グラクソ グループ リミテッド | 分配デバイス |
| JP2020517385A (ja) * | 2017-04-28 | 2020-06-18 | ソフトハレ エヌヴイSofthale Nv | 吸入装置および方法 |
| JP2021529626A (ja) * | 2018-07-16 | 2021-11-04 | ソフトハレ エヌヴイSofthale Nv | 改善された吸入デバイス |
| JP2024526514A (ja) * | 2022-07-01 | 2024-07-19 | ケーティー アンド ジー コーポレイション | インヘイラー |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04011108A (es) * | 2002-05-09 | 2005-02-14 | Glaxo Group Ltd | Dispositivo distribuidor de fluidos. |
| GB0405477D0 (en) * | 2004-03-11 | 2004-04-21 | Glaxo Group Ltd | A fluid dispensing device |
| ES2388434T3 (es) | 2003-11-03 | 2012-10-15 | Glaxo Group Limited | Dispositivo de administración de fluido |
| GB0507224D0 (en) * | 2005-04-09 | 2005-05-18 | Glaxo Group Ltd | A fluid dispensing device |
| AU2008243638B2 (en) * | 2007-04-30 | 2012-05-17 | Kisling Ag | Metering device |
| FR2929252B1 (fr) * | 2008-03-27 | 2012-02-03 | Rexam Pharma La Verpilliere | Dispositif de distribution de fluide comprenant une pompe |
| FR2932399B1 (fr) * | 2008-06-17 | 2011-10-28 | Valois Sas | Dispositif de distribution de produit fluide |
| FR2932400B1 (fr) * | 2008-06-17 | 2011-11-18 | Valois Sas | Dispositif de distribution de produit fluide |
| PL3184136T3 (pl) | 2010-03-25 | 2022-01-17 | New Injection Systems Ltd | Wstrzykiwacz |
| SG184478A1 (en) | 2010-04-06 | 2012-11-29 | Reseal Internat Ltd Partnership | Delivery system for dispensing metered volumes of pure or sterile flowable substances |
| FR2973011B1 (fr) | 2011-03-21 | 2013-04-26 | Valois Sas | Dispositif de distribution de produit fluide a actionnement lateral. |
| FR2973012B1 (fr) | 2011-03-21 | 2013-04-26 | Valois Sas | Dispositif de distribution de produit fluide a actionnement lateral. |
| FR2973014B1 (fr) | 2011-03-21 | 2014-06-06 | Valois Sas | Dispositif de distribution de produit fluide a actionnement lateral. |
| FR2973013B1 (fr) | 2011-03-21 | 2014-06-06 | Valois Sas | Dispositif de distribution de produit fluide a actionnement lateral. |
| FR2973010B1 (fr) | 2011-03-21 | 2013-04-26 | Valois Sas | Dispositif de distribution de produit fluide a actionnement lateral. |
| DE112011105781T5 (de) * | 2011-10-27 | 2014-09-04 | Victor Esteve | Medikamentenabgabevorrichtung |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02246976A (ja) * | 1988-12-20 | 1990-10-02 | Technique De Pulverisation Step:Soc | 液体又はクリーム状の物質を小滴状に分与する分与装置及びこの分与装置を包含する分与組立体 |
| JPH06134021A (ja) * | 1991-04-05 | 1994-05-17 | Technique De Pulverisation Step:Soc | 小量の液滴を分与する装置 |
| JP2002018330A (ja) * | 2000-07-03 | 2002-01-22 | Top:Kk | 吐出容器 |
| JP2002080081A (ja) * | 2000-09-07 | 2002-03-19 | Mitani Valve Co Ltd | 内容物放出機構 |
| JP2002087478A (ja) * | 2000-05-19 | 2002-03-27 | L'oreal Sa | 投液ノズルと該ノズルを備えた分配装置 |
| FR2834920A1 (fr) * | 2002-01-22 | 2003-07-25 | Valois Sa | Dispositif de pulverisation a actionnement lateral |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2325346A1 (fr) * | 1975-09-26 | 1977-04-22 | Broilliard Bernard | Perfectionnements a un distributeur doseur pour des produits liquides ou pateux |
| US4315582A (en) * | 1977-05-02 | 1982-02-16 | Leeds And Micallef | Universal sequential dispensing pump system free of external check valves and having venting capability |
| US4623337A (en) * | 1984-03-08 | 1986-11-18 | Alpha Group, Inc. | Liquid dispensing apparatus |
| DE3445562A1 (de) * | 1984-12-14 | 1986-06-19 | Ing. Erich Pfeiffer GmbH & Co KG, 7760 Radolfzell | Schubkolben-pumpe fuer wirkstoff-spender |
| DE3517558A1 (de) * | 1985-05-15 | 1986-11-20 | Ing. Erich Pfeiffer GmbH & Co KG, 7760 Radolfzell | Handbetaetigte ausgabeeinrichtung fuer medien |
| GB2243880B (en) * | 1990-05-01 | 1994-03-16 | Bespak Plc | Dispensing device |
| US5085351A (en) * | 1990-11-05 | 1992-02-04 | Martin James H | Adjustable dose dispenser |
| WO1993000172A1 (fr) * | 1991-06-26 | 1993-01-07 | Valois (Societe Anonyme) | Dispositif pour projeter une dose predeterminee d'un produit fluide, et son procede de remplissage |
| GB2272389B (en) * | 1992-11-04 | 1996-07-24 | Bespak Plc | Dispensing apparatus |
| US5464120A (en) * | 1994-05-27 | 1995-11-07 | Flurry International, Inc. | Method and apparatus for frozen dessert dispensing |
| DE19622124A1 (de) * | 1996-06-01 | 1997-12-04 | Alfred Von Schuckmann | Gerät zum Aufbringen von Flüssigkeiten |
| CA2389294A1 (en) * | 1999-11-08 | 2001-05-25 | Capnia, Incorporated | Method and apparatus for relieving ailments using gases to increase the effectiveness of drugs |
| GB0016123D0 (en) * | 2000-07-01 | 2000-08-23 | Glaxo Group Ltd | Valve for aerosol container |
| DE10032976A1 (de) * | 2000-07-06 | 2002-01-17 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung für Medien |
| GB0109861D0 (en) * | 2001-04-20 | 2001-06-13 | Syngenta Ltd | Fluid dispensing systems |
| US6745760B2 (en) * | 2001-05-15 | 2004-06-08 | Trudell Medical International | Medicament applicator |
| JP4477355B2 (ja) * | 2002-01-07 | 2010-06-09 | エアロジェン,インコーポレイテッド | 吸入のために流体を噴霧するためのデバイスおよび方法 |
| DE10231751B4 (de) * | 2002-07-13 | 2004-07-29 | Aero Pump GmbH, Zerstäuberpumpen | Saug-Druck-Pumpe zum Ausspritzen eines Produkts aus einem Behältnis |
-
2004
- 2004-02-06 GB GBGB0402695.1A patent/GB0402695D0/en not_active Ceased
-
2005
- 2005-02-04 CN CN200580009505A patent/CN100594071C/zh not_active Expired - Fee Related
- 2005-02-04 US US10/597,692 patent/US20070095853A1/en not_active Abandoned
- 2005-02-04 CA CA002555298A patent/CA2555298A1/en not_active Abandoned
- 2005-02-04 WO PCT/GB2005/000416 patent/WO2005075105A1/en not_active Ceased
- 2005-02-04 JP JP2006551928A patent/JP2007520349A/ja active Pending
- 2005-02-04 BR BRPI0507396-0A patent/BRPI0507396A/pt not_active IP Right Cessation
- 2005-02-04 AU AU2005210216A patent/AU2005210216A1/en not_active Abandoned
- 2005-02-04 EP EP05708247A patent/EP1711276A1/en not_active Withdrawn
-
2006
- 2006-08-03 ZA ZA200606463A patent/ZA200606463B/en unknown
-
2010
- 2010-09-24 US US12/889,445 patent/US20110011889A1/en not_active Abandoned
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02246976A (ja) * | 1988-12-20 | 1990-10-02 | Technique De Pulverisation Step:Soc | 液体又はクリーム状の物質を小滴状に分与する分与装置及びこの分与装置を包含する分与組立体 |
| JPH06134021A (ja) * | 1991-04-05 | 1994-05-17 | Technique De Pulverisation Step:Soc | 小量の液滴を分与する装置 |
| JP2002087478A (ja) * | 2000-05-19 | 2002-03-27 | L'oreal Sa | 投液ノズルと該ノズルを備えた分配装置 |
| JP2002018330A (ja) * | 2000-07-03 | 2002-01-22 | Top:Kk | 吐出容器 |
| JP2002080081A (ja) * | 2000-09-07 | 2002-03-19 | Mitani Valve Co Ltd | 内容物放出機構 |
| FR2834920A1 (fr) * | 2002-01-22 | 2003-07-25 | Valois Sa | Dispositif de pulverisation a actionnement lateral |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011508613A (ja) * | 2007-11-29 | 2011-03-17 | グラクソ グループ リミテッド | 分配デバイス |
| JP2020517385A (ja) * | 2017-04-28 | 2020-06-18 | ソフトハレ エヌヴイSofthale Nv | 吸入装置および方法 |
| US11612704B2 (en) | 2017-04-28 | 2023-03-28 | Softhale Nv | Inhalation device and method |
| JP7275046B2 (ja) | 2017-04-28 | 2023-05-17 | ソフトハレ エヌヴイ | 吸入装置および方法 |
| US12434022B2 (en) | 2017-04-28 | 2025-10-07 | Invox Belgium Nv | Inhalation device and method |
| JP2021529626A (ja) * | 2018-07-16 | 2021-11-04 | ソフトハレ エヌヴイSofthale Nv | 改善された吸入デバイス |
| JP7422727B2 (ja) | 2018-07-16 | 2024-01-26 | インヴォックス ベルジアム エヌヴイ | 改善された吸入デバイス |
| US12178956B2 (en) | 2018-07-16 | 2024-12-31 | Invox Belgium Nv | Inhalation device |
| JP2024526514A (ja) * | 2022-07-01 | 2024-07-19 | ケーティー アンド ジー コーポレイション | インヘイラー |
| JP7739695B2 (ja) | 2022-07-01 | 2025-09-17 | ケーティー アンド ジー コーポレイション | インヘイラー |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005210216A1 (en) | 2005-08-18 |
| GB0402695D0 (en) | 2004-03-10 |
| US20110011889A1 (en) | 2011-01-20 |
| EP1711276A1 (en) | 2006-10-18 |
| CA2555298A1 (en) | 2005-08-18 |
| BRPI0507396A (pt) | 2007-07-10 |
| US20070095853A1 (en) | 2007-05-03 |
| CN100594071C (zh) | 2010-03-17 |
| CN1933917A (zh) | 2007-03-21 |
| ZA200606463B (en) | 2008-02-27 |
| WO2005075105A1 (en) | 2005-08-18 |
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