JP2007518825A5 - - Google Patents
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- Publication number
- JP2007518825A5 JP2007518825A5 JP2006551442A JP2006551442A JP2007518825A5 JP 2007518825 A5 JP2007518825 A5 JP 2007518825A5 JP 2006551442 A JP2006551442 A JP 2006551442A JP 2006551442 A JP2006551442 A JP 2006551442A JP 2007518825 A5 JP2007518825 A5 JP 2007518825A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- poam
- alkyl
- moiety
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53857304P | 2004-01-23 | 2004-01-23 | |
| PCT/US2005/002478 WO2005070921A1 (en) | 2004-01-23 | 2005-01-24 | Polyethylene glycol conjugates of heterocycloalkyl carboxamido propanoic acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007518825A JP2007518825A (ja) | 2007-07-12 |
| JP2007518825A5 true JP2007518825A5 (https=) | 2009-04-09 |
Family
ID=34807197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551442A Pending JP2007518825A (ja) | 2004-01-23 | 2005-01-24 | 複素環式アルキルカルボキサミドプロパノン酸類のポリエチレングリコール抱合体類 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7595318B2 (https=) |
| EP (1) | EP1706399A1 (https=) |
| JP (1) | JP2007518825A (https=) |
| CA (1) | CA2554188A1 (https=) |
| WO (1) | WO2005070921A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7794700B2 (en) | 2004-07-08 | 2010-09-14 | Elan Pharmaceuticals Inc. | Multimeric VLA-4 antagonists comprising polymer moieties |
| MX2007014267A (es) | 2005-05-20 | 2008-02-07 | Elan Pharm Inc | Derivados de imidazolona fenilamina como antagonistas vla-4. |
| NZ564836A (en) * | 2005-07-08 | 2011-10-28 | Elan Pharm Inc | Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds |
| MX2008014520A (es) * | 2006-05-22 | 2008-11-27 | Elan Pharm Inc | Preparacion de conjugados polimericos de compuestos terapeuticos, agricolas, y de aditivos para alimentos. |
| EP2125027A2 (en) * | 2007-03-12 | 2009-12-02 | Nektar Therapeutics | De novo synthesis of conjugates |
| WO2015048819A1 (en) | 2013-09-30 | 2015-04-02 | The Regents Of The University Of California | Anti-alphavbeta1 integrin compounds and methods |
| WO2016145258A1 (en) | 2015-03-10 | 2016-09-15 | The Regents Of The University Of California | Anti-alphavbeta1 integrin inhibitors and methods of use |
| KR20210018820A (ko) | 2018-05-04 | 2021-02-18 | 안티센스 테라퓨틱스 엘티디 | 치료 용도 및 방법 |
| ES3013256T3 (en) | 2018-10-30 | 2025-04-11 | Gilead Sciences Inc | Imidazo[1,2-a]pyridine derivatives as alpha4beta7 integrin inhibitors for the treatment of inflammatory diseases |
| JP7189368B2 (ja) | 2018-10-30 | 2022-12-13 | ギリアード サイエンシーズ， インコーポレイテッド | アルファ４ベータ７インテグリンの阻害のための化合物 |
| FI3873884T3 (fi) | 2018-10-30 | 2025-02-24 | Gilead Sciences Inc | 3-(kinolin-8-yyli)-1,4-dihydropyrido[3,4-d]pyrimidiini-2,4-dionijohdannaisia alfa-4-beta-7-integriinin estäjinä tulehdussairauksien hoidossa |
| EP3873605B1 (en) | 2018-10-30 | 2024-10-23 | Gilead Sciences, Inc. | Compounds for inhibition of alpha4beta7 integrin |
| WO2021030438A1 (en) | 2019-08-14 | 2021-02-18 | Gilead Sciences, Inc. | Compounds for inhibition of alpha 4 beta 7 integrin |
| US20220023227A1 (en) * | 2020-07-24 | 2022-01-27 | Georgia Southern University Research And Service Foundation, Inc. | Systems and methods for forming nanocapsules by pulsed electrospraying |
| WO2022266498A1 (en) * | 2021-06-17 | 2022-12-22 | Nektar Therapeutics | Histidine-selective polymer reagents |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4604103A (en) * | 1982-07-30 | 1986-08-05 | Chevron Research Company | Deposit control additives--polyether polyamine ethanes |
| US5510332A (en) * | 1994-07-07 | 1996-04-23 | Texas Biotechnology Corporation | Process to inhibit binding of the integrin α4 62 1 to VCAM-1 or fibronectin and linear peptides therefor |
| AU2964295A (en) | 1994-07-11 | 1996-02-09 | Athena Neurosciences, Inc. | Inhibitors of leukocyte adhesion |
| EP1001764A4 (en) * | 1997-05-29 | 2005-08-24 | Merck & Co Inc | HETEROCYCLIC AMIDE COMPOUNDS AS INHIBITORS OF CELL ADHESION |
| AR016133A1 (es) * | 1997-07-31 | 2001-06-20 | Wyeth Corp | Compuesto de carbamiloxi que inhiben la adhesion de leucocitos mediada por vla-4, compuestos que son prodrogas de dichos compuestos, composicionfarmaceutica, metodo para fijar vla-4 a una muestra biologica, metodo para el tratamiento de una condicion inflamatoria |
| US6489300B1 (en) * | 1997-07-31 | 2002-12-03 | Eugene D. Thorsett | Carbamyloxy compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| US6436904B1 (en) * | 1999-01-25 | 2002-08-20 | Elan Pharmaceuticals, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| CZ2002518A3 (cs) * | 1999-08-13 | 2002-05-15 | Biogen, Inc. | Inhibitory buněčné adheze a farmaceutické prostředky, které je obsahují |
| EP1251866A1 (en) * | 2000-01-24 | 2002-10-30 | Schering Corporation | Combination of temozolomide and pegylated interferon-alpha for treating cancer |
| WO2001054690A1 (en) * | 2000-01-28 | 2001-08-02 | Biogen, Inc. | Pharmaceutical compositions containing anti-beta 1 integrin compounds and uses |
| AU2002213343A1 (en) * | 2000-10-18 | 2002-04-29 | Schering Corporation | Ribavirin-pegylated interferon alfa HCV combination therapy |
| US20040208844A1 (en) * | 2001-08-01 | 2004-10-21 | Francis Ignatious | Products and drug delivery vehicles |
| EP1450844A4 (en) * | 2001-11-09 | 2009-07-29 | Enzon Inc | POLYMER THIOL-LINKED PRODRUGS USING BENZYL ELIMINATION SYSTEMS |
| US6608076B1 (en) * | 2002-05-16 | 2003-08-19 | Enzon, Inc. | Camptothecin derivatives and polymeric conjugates thereof |
| CA2514117A1 (en) | 2003-01-24 | 2004-08-12 | Elan Pharmaceuticals, Inc. | Composition for and treatment of demyelinating diseases and paralysis by administration of remyelinating agents |
| US7605166B2 (en) * | 2003-06-25 | 2009-10-20 | Elan Pharmaceuticals Inc. | Methods and compositions for treating rheumatoid arthritis |
| US7794700B2 (en) * | 2004-07-08 | 2010-09-14 | Elan Pharmaceuticals Inc. | Multimeric VLA-4 antagonists comprising polymer moieties |
| MX2007014267A (es) * | 2005-05-20 | 2008-02-07 | Elan Pharm Inc | Derivados de imidazolona fenilamina como antagonistas vla-4. |
| NZ564836A (en) * | 2005-07-08 | 2011-10-28 | Elan Pharm Inc | Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds |
-
2005
- 2005-01-24 CA CA002554188A patent/CA2554188A1/en not_active Abandoned
- 2005-01-24 EP EP05712086A patent/EP1706399A1/en not_active Withdrawn
- 2005-01-24 JP JP2006551442A patent/JP2007518825A/ja active Pending
- 2005-01-24 WO PCT/US2005/002478 patent/WO2005070921A1/en not_active Ceased
- 2005-01-24 US US11/042,734 patent/US7595318B2/en not_active Expired - Fee Related
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