JP2007518825A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2007518825A5 JP2007518825A5 JP2006551442A JP2006551442A JP2007518825A5 JP 2007518825 A5 JP2007518825 A5 JP 2007518825A5 JP 2006551442 A JP2006551442 A JP 2006551442A JP 2006551442 A JP2006551442 A JP 2006551442A JP 2007518825 A5 JP2007518825 A5 JP 2007518825A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- poam
- alkyl
- moiety
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53857304P | 2004-01-23 | 2004-01-23 | |
| PCT/US2005/002478 WO2005070921A1 (en) | 2004-01-23 | 2005-01-24 | Polyethylene glycol conjugates of heterocycloalkyl carboxamido propanoic acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007518825A JP2007518825A (ja) | 2007-07-12 |
| JP2007518825A5 true JP2007518825A5 (enExample) | 2009-04-09 |
Family
ID=34807197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551442A Pending JP2007518825A (ja) | 2004-01-23 | 2005-01-24 | 複素環式アルキルカルボキサミドプロパノン酸類のポリエチレングリコール抱合体類 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7595318B2 (enExample) |
| EP (1) | EP1706399A1 (enExample) |
| JP (1) | JP2007518825A (enExample) |
| CA (1) | CA2554188A1 (enExample) |
| WO (1) | WO2005070921A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2298356A3 (en) * | 2004-07-08 | 2011-08-10 | Elan Pharmaceuticals, Inc. | Multivalent VLA-4 antagonists comprising polymer moieties |
| CN101300255A (zh) | 2005-05-20 | 2008-11-05 | 艾伦药物公司 | 咪唑啉酮苯丙氨酸衍生物vla-4拮抗剂 |
| SG196786A1 (en) | 2005-07-08 | 2014-02-13 | Elan Pharm Inc | Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds |
| EP2019690A2 (en) * | 2006-05-22 | 2009-02-04 | Elan Pharmaceuticals Inc. | Preparation of polymer conjugates of vla-4 antagonists via a mitsunobu's reaction |
| US20100184989A1 (en) * | 2007-03-12 | 2010-07-22 | Nektar Therapeutics | De Novo Synthesis of Conjugates |
| WO2015048819A1 (en) | 2013-09-30 | 2015-04-02 | The Regents Of The University Of California | Anti-alphavbeta1 integrin compounds and methods |
| WO2016145258A1 (en) | 2015-03-10 | 2016-09-15 | The Regents Of The University Of California | Anti-alphavbeta1 integrin inhibitors and methods of use |
| WO2019210347A1 (en) | 2018-05-04 | 2019-11-07 | Antisense Therapeutics Ltd | Therapeutic uses and methods |
| ES3013256T3 (en) | 2018-10-30 | 2025-04-11 | Gilead Sciences Inc | Imidazo[1,2-a]pyridine derivatives as alpha4beta7 integrin inhibitors for the treatment of inflammatory diseases |
| CN112996786B (zh) | 2018-10-30 | 2024-08-20 | 吉利德科学公司 | 用于抑制α4β7整合素的化合物 |
| US11179383B2 (en) | 2018-10-30 | 2021-11-23 | Gilead Sciences, Inc. | Compounds for inhibition of α4β7 integrin |
| WO2020092375A1 (en) | 2018-10-30 | 2020-05-07 | Gilead Sciences, Inc. | Quinoline derivatives as alpha4beta7 integrin inhibitors |
| US11578069B2 (en) | 2019-08-14 | 2023-02-14 | Gilead Sciences, Inc. | Compounds for inhibition of α4 β7 integrin |
| US20220023227A1 (en) * | 2020-07-24 | 2022-01-27 | Georgia Southern University Research And Service Foundation, Inc. | Systems and methods for forming nanocapsules by pulsed electrospraying |
| WO2022266498A1 (en) * | 2021-06-17 | 2022-12-22 | Nektar Therapeutics | Histidine-selective polymer reagents |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4604103A (en) * | 1982-07-30 | 1986-08-05 | Chevron Research Company | Deposit control additives--polyether polyamine ethanes |
| US5510332A (en) * | 1994-07-07 | 1996-04-23 | Texas Biotechnology Corporation | Process to inhibit binding of the integrin α4 62 1 to VCAM-1 or fibronectin and linear peptides therefor |
| WO1996001644A1 (en) | 1994-07-11 | 1996-01-25 | Athena Neurosciences, Inc. | Inhibitors of leukocyte adhesion |
| EP1001764A4 (en) * | 1997-05-29 | 2005-08-24 | Merck & Co Inc | HETEROCYCLIC AMIDE COMPOUNDS AS INHIBITORS OF CELL ADHESION |
| US6489300B1 (en) * | 1997-07-31 | 2002-12-03 | Eugene D. Thorsett | Carbamyloxy compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| AR016133A1 (es) * | 1997-07-31 | 2001-06-20 | Wyeth Corp | Compuesto de carbamiloxi que inhiben la adhesion de leucocitos mediada por vla-4, compuestos que son prodrogas de dichos compuestos, composicionfarmaceutica, metodo para fijar vla-4 a una muestra biologica, metodo para el tratamiento de una condicion inflamatoria |
| US6436904B1 (en) * | 1999-01-25 | 2002-08-20 | Elan Pharmaceuticals, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| RS50470B (sr) * | 1999-08-13 | 2010-03-02 | Biogen Idec Ma Inc. | Inhibitori ćelijske adhezije |
| US20020009428A1 (en) * | 2000-01-24 | 2002-01-24 | Zaknoen Sara L. | Combination therapy for cancer |
| EP1253923A1 (en) * | 2000-01-28 | 2002-11-06 | Biogen, Inc. | Pharmaceutical compositions containing anti-beta 1 integrin compounds and uses |
| CN1516599A (zh) * | 2000-10-18 | 2004-07-28 | ���鹫˾ | 病毒唑-聚乙二醇化干扰素α联合治疗慢性传染性丙型肝炎的方法 |
| AU2002326494A1 (en) * | 2001-08-01 | 2003-02-17 | Smithkline Beecham Corporation | Products and drug delivery vehicles |
| JP4663233B2 (ja) * | 2001-11-09 | 2011-04-06 | エンゾン，インコーポレーテッド | ベンジル脱離系を利用する高分子チオール結合プロドラッグ |
| US6608076B1 (en) * | 2002-05-16 | 2003-08-19 | Enzon, Inc. | Camptothecin derivatives and polymeric conjugates thereof |
| SK50642005A3 (sk) | 2003-01-24 | 2006-02-02 | Elan Pharmaceuticals, Inc. | Kompozícia na liečenie demyelizačných ochorení a paralýzy podávaním remyelizačných látok |
| UY28391A1 (es) * | 2003-06-25 | 2004-12-31 | Elan Pharm Inc | Metodos y composiciones para tratar artritis reumatoide |
| EP2298356A3 (en) * | 2004-07-08 | 2011-08-10 | Elan Pharmaceuticals, Inc. | Multivalent VLA-4 antagonists comprising polymer moieties |
| CN101300255A (zh) * | 2005-05-20 | 2008-11-05 | 艾伦药物公司 | 咪唑啉酮苯丙氨酸衍生物vla-4拮抗剂 |
| SG196786A1 (en) * | 2005-07-08 | 2014-02-13 | Elan Pharm Inc | Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds |
-
2005
- 2005-01-24 JP JP2006551442A patent/JP2007518825A/ja active Pending
- 2005-01-24 WO PCT/US2005/002478 patent/WO2005070921A1/en not_active Ceased
- 2005-01-24 CA CA002554188A patent/CA2554188A1/en not_active Abandoned
- 2005-01-24 US US11/042,734 patent/US7595318B2/en not_active Expired - Fee Related
- 2005-01-24 EP EP05712086A patent/EP1706399A1/en not_active Withdrawn