JP2007518670A - 苦味のある薬物、及びｐＨ感受性ポリマーを含む風味マスクされた医薬組成物 - Google Patents
苦味のある薬物、及びｐＨ感受性ポリマーを含む風味マスクされた医薬組成物 Download PDFInfo
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- JP2007518670A JP2007518670A JP2005511660A JP2005511660A JP2007518670A JP 2007518670 A JP2007518670 A JP 2007518670A JP 2005511660 A JP2005511660 A JP 2005511660A JP 2005511660 A JP2005511660 A JP 2005511660A JP 2007518670 A JP2007518670 A JP 2007518670A
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- drug
- methacrylate
- polymer
- ethyl
- acrylate
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- 239000003814 drug Substances 0.000 title claims abstract description 197
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- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 27
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- GSDSWSVVBLHKDQ-UHFFFAOYSA-N 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Chemical compound FC1=CC(C(C(C(O)=O)=C2)=O)=C3N2C(C)COC3=C1N1CCN(C)CC1 GSDSWSVVBLHKDQ-UHFFFAOYSA-N 0.000 claims description 7
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- MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 claims description 6
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- 210000001779 taste bud Anatomy 0.000 description 1
- LJVAJPDWBABPEJ-PNUFFHFMSA-N telithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)[C@@H](C)C(=O)O[C@@H]([C@]2(OC(=O)N(CCCCN3C=C(N=C3)C=3C=NC=CC=3)[C@@H]2[C@@H](C)C(=O)[C@H](C)C[C@@]1(C)OC)C)CC)[C@@H]1O[C@H](C)C[C@H](N(C)C)[C@H]1O LJVAJPDWBABPEJ-PNUFFHFMSA-N 0.000 description 1
- 229960003250 telithromycin Drugs 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 description 1
- 239000004563 wettable powder Substances 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2003/000392 WO2005055987A1 (fr) | 2003-12-15 | 2003-12-15 | Compositions pharmaceutiques au gout masque comportant une medicament amer et un polymere sensible au ph |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2007518670A true JP2007518670A (ja) | 2007-07-12 |
Family
ID=34674529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005511660A Pending JP2007518670A (ja) | 2003-12-15 | 2003-12-15 | 苦味のある薬物、及びｐＨ感受性ポリマーを含む風味マスクされた医薬組成物 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1694302A1 (fr) |
| JP (1) | JP2007518670A (fr) |
| CN (1) | CN1878539B (fr) |
| AU (1) | AU2003292509B2 (fr) |
| CA (1) | CA2549572A1 (fr) |
| WO (1) | WO2005055987A1 (fr) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007518669A (ja) * | 2003-12-15 | 2007-07-12 | カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ | ｐＨ感受性ポリマーを含む風味マスクされる医薬組成物 |
| JP2011162458A (ja) * | 2010-02-05 | 2011-08-25 | Sawai Pharmaceutical Co Ltd | 薬物の不快な味をマスキングした経口医薬組成物 |
| JP2012046496A (ja) * | 2010-07-30 | 2012-03-08 | Taisho Pharmaceutical Co Ltd | 内服液剤 |
| JP2014517020A (ja) * | 2011-06-17 | 2014-07-17 | エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング | エタノールの影響に耐性のある胃液抵抗性の医薬又は栄養補助組成物 |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009035505A (ja) * | 2007-08-01 | 2009-02-19 | Takada Seiyaku Kk | レボフロキサシン錠剤 |
| CN102188406B (zh) * | 2011-05-12 | 2015-02-25 | 黑龙江大学 | 盐酸左氧氟沙星掩味微胶囊的生产方法 |
| CN102344520B (zh) * | 2011-07-12 | 2015-04-22 | 华东理工大学 | 两种pH敏感再生型聚合物、其制备方法和形成的再生型两水相体系及应用 |
| CN102302472B (zh) * | 2011-09-08 | 2012-08-01 | 河南迪冉生物科技有限公司 | 恩诺沙星微囊及其制备方法 |
| CN103191680B (zh) * | 2013-03-26 | 2016-02-24 | 厦门大学 | 一种pH敏感的复合中空微球及其制备方法 |
| EA201791251A1 (ru) | 2014-12-05 | 2017-11-30 | Арагон Фармасьютикалз, Инк. | Противораковые композиции |
| EP3226842B1 (fr) * | 2014-12-05 | 2020-11-25 | Aragon Pharmaceuticals, Inc. | Compositions anticancéreuses |
| CA3026611A1 (fr) * | 2016-06-21 | 2017-12-28 | Laila Nutraceuticals | Formulation masquant le gout de composes naturels amers |
| WO2018047201A2 (fr) * | 2016-09-08 | 2018-03-15 | Laila Nutraceuticals | Formulations de masquage d'odeur pour composés naturels |
| CN114209661B (zh) * | 2022-02-21 | 2022-04-29 | 北京罗诺强施医药技术研发中心有限公司 | 呈细粒形式的固体药物组合物 |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4873378A (fr) * | 1971-12-30 | 1973-10-03 | ||
| JPS497170A (fr) * | 1972-05-13 | 1974-01-22 | ||
| JPS5793912A (en) * | 1980-10-06 | 1982-06-11 | Sutooru Research Ando Dev Corp | Manufacture of microcapsule |
| JPS5872516A (ja) * | 1981-10-08 | 1983-04-30 | ア・エ・セ・ソシエテ・ドウ・シミ−・オルガニツク・エ・ビオロジツク | 生物学的活性物質を被覆するための新規組成物 |
| JPS63112513A (ja) * | 1986-10-21 | 1988-05-17 | アメリカン・ホーム・プロダクツ・コーポレイシヨン | スプレードライしたアセトアミノフェン |
| JPH05509088A (ja) * | 1990-07-18 | 1993-12-16 | ビーチャム・グループ・パブリック・リミテッド・カンパニー | 微粒子マトリックス含有組成物 |
| JP2001518490A (ja) * | 1997-10-03 | 2001-10-16 | エラン コーポレーシヨン ピーエルシー | 味遮蔽された製剤 |
| JP2007518669A (ja) * | 2003-12-15 | 2007-07-12 | カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ | ｐＨ感受性ポリマーを含む風味マスクされる医薬組成物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5286489A (en) * | 1985-08-26 | 1994-02-15 | The Procter & Gamble Company | Taste masking compositions |
| US5445830A (en) * | 1989-07-25 | 1995-08-29 | Otsuka Pharmaceutical Co., Ltd. | Highly absorbable pharmaceutical composition |
| CN1023766C (zh) * | 1990-04-09 | 1994-02-16 | 沈阳药学院 | 制备无味药物微囊的喷雾干燥工艺 |
| US5851538A (en) * | 1995-12-29 | 1998-12-22 | Advanced Polymer Systems, Inc. | Retinoid formulations in porous microspheres for reduced irritation and enhanced stability |
| DE19918435A1 (de) * | 1998-07-23 | 2000-01-27 | Roehm Gmbh | Überzugs- und Bindemittel für orale oder dermale Arzneiformen |
| AU4943000A (en) * | 1999-06-11 | 2001-01-02 | Ranbaxy Laboratories Limited | Taste masked compositions |
| ITMI20012572A1 (it) * | 2001-12-06 | 2003-06-06 | Istituto Biochimico Italiano | Microgranuli di acido ursodesossicolico |
-
2003
- 2003-12-15 WO PCT/IN2003/000392 patent/WO2005055987A1/fr active IP Right Grant
- 2003-12-15 CN CN200380110830XA patent/CN1878539B/zh not_active Expired - Fee Related
- 2003-12-15 EP EP03768091A patent/EP1694302A1/fr not_active Withdrawn
- 2003-12-15 AU AU2003292509A patent/AU2003292509B2/en not_active Ceased
- 2003-12-15 JP JP2005511660A patent/JP2007518670A/ja active Pending
- 2003-12-15 CA CA002549572A patent/CA2549572A1/fr not_active Abandoned
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4873378A (fr) * | 1971-12-30 | 1973-10-03 | ||
| JPS497170A (fr) * | 1972-05-13 | 1974-01-22 | ||
| JPS5793912A (en) * | 1980-10-06 | 1982-06-11 | Sutooru Research Ando Dev Corp | Manufacture of microcapsule |
| JPS5872516A (ja) * | 1981-10-08 | 1983-04-30 | ア・エ・セ・ソシエテ・ドウ・シミ−・オルガニツク・エ・ビオロジツク | 生物学的活性物質を被覆するための新規組成物 |
| JPS63112513A (ja) * | 1986-10-21 | 1988-05-17 | アメリカン・ホーム・プロダクツ・コーポレイシヨン | スプレードライしたアセトアミノフェン |
| JPH05509088A (ja) * | 1990-07-18 | 1993-12-16 | ビーチャム・グループ・パブリック・リミテッド・カンパニー | 微粒子マトリックス含有組成物 |
| JP2001518490A (ja) * | 1997-10-03 | 2001-10-16 | エラン コーポレーシヨン ピーエルシー | 味遮蔽された製剤 |
| JP2007518669A (ja) * | 2003-12-15 | 2007-07-12 | カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ | ｐＨ感受性ポリマーを含む風味マスクされる医薬組成物 |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007518669A (ja) * | 2003-12-15 | 2007-07-12 | カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ | ｐＨ感受性ポリマーを含む風味マスクされる医薬組成物 |
| JP2011162458A (ja) * | 2010-02-05 | 2011-08-25 | Sawai Pharmaceutical Co Ltd | 薬物の不快な味をマスキングした経口医薬組成物 |
| JP2012046496A (ja) * | 2010-07-30 | 2012-03-08 | Taisho Pharmaceutical Co Ltd | 内服液剤 |
| JP2014517020A (ja) * | 2011-06-17 | 2014-07-17 | エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング | エタノールの影響に耐性のある胃液抵抗性の医薬又は栄養補助組成物 |
| US9775815B2 (en) | 2011-06-17 | 2017-10-03 | Evonik Roehm Gmbh | Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003292509B2 (en) | 2007-08-02 |
| WO2005055987A1 (fr) | 2005-06-23 |
| AU2003292509B9 (en) | 2005-06-29 |
| CN1878539A (zh) | 2006-12-13 |
| CA2549572A1 (fr) | 2005-06-23 |
| CN1878539B (zh) | 2010-06-23 |
| AU2003292509A1 (en) | 2005-06-29 |
| EP1694302A1 (fr) | 2006-08-30 |
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