JP2007518071A - 生体分子のマーキング方法および装置 - Google Patents

生体分子のマーキング方法および装置 Download PDF

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Publication number
JP2007518071A
JP2007518071A JP2006544232A JP2006544232A JP2007518071A JP 2007518071 A JP2007518071 A JP 2007518071A JP 2006544232 A JP2006544232 A JP 2006544232A JP 2006544232 A JP2006544232 A JP 2006544232A JP 2007518071 A JP2007518071 A JP 2007518071A
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JP
Japan
Prior art keywords
micromixer
solution
reaction
labeling
volume
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JP2006544232A
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English (en)
Japanese (ja)
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JP2007518071A5 (https=
Inventor
アレクサンダー・アツァヴィ
シュテファン・ダーシュム
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ehrfeld Mikrotechnik BTS GmbH
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Ehrfeld Mikrotechnik BTS GmbH
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Publication date
Application filed by Ehrfeld Mikrotechnik BTS GmbH filed Critical Ehrfeld Mikrotechnik BTS GmbH
Publication of JP2007518071A publication Critical patent/JP2007518071A/ja
Publication of JP2007518071A5 publication Critical patent/JP2007518071A5/ja
Pending legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572—Chemical means
    • B01J2219/00576—Chemical means fluorophore
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00788—Three-dimensional assemblies, i.e. the reactor comprising a form other than a stack of plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00851—Additional features
    • B01J2219/00858—Aspects relating to the size of the reactor
    • B01J2219/0086—Dimensions of the flow channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00873—Heat exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00889—Mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/0095—Control aspects
    • B01J2219/00984—Residence time

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Dot-Matrix Printers And Others (AREA)
JP2006544232A 2003-12-20 2004-10-28 生体分子のマーキング方法および装置 Pending JP2007518071A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10350484A DE10350484B4 (de) 2003-12-20 2003-12-20 Verfahren und Vorrichtung zur Markierung von Proteinen
PCT/EP2004/012172 WO2005064335A2 (de) 2003-12-20 2004-10-28 Verfahren und vorrichtung zur markierung von biomolekülen

Publications (2)

Publication Number Publication Date
JP2007518071A true JP2007518071A (ja) 2007-07-05
JP2007518071A5 JP2007518071A5 (https=) 2007-12-13

Family

ID=34706241

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006544232A Pending JP2007518071A (ja) 2003-12-20 2004-10-28 生体分子のマーキング方法および装置

Country Status (6)

Country Link
US (1) US20080058506A1 (https=)
EP (1) EP1697747B1 (https=)
JP (1) JP2007518071A (https=)
AT (1) ATE416382T1 (https=)
DE (2) DE10350484B4 (https=)
WO (1) WO2005064335A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005049294C5 (de) * 2005-10-14 2012-05-03 Ehrfeld Mikrotechnik Bts Gmbh Verfahren zur Herstellung organischer Peroxide mittels Mikroreaktionstechnik
CN111246936B (zh) * 2017-10-25 2022-05-03 深圳华大生命科学研究院 用于核酸合成的微流控芯片
CN108927082A (zh) * 2018-07-03 2018-12-04 江苏省原子医学研究所 一种氟化铝标记的微流反应装置

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11510595A (ja) * 1995-06-07 1999-09-14 バイオセプラ，インコーポレイテッド 螢光分光光度計測による流体中の所期の溶質のオンライン検出

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244816A (en) * 1989-10-11 1993-09-14 Akzo N.V. Method for purifying chelator conjugated compounds
DE4408729A1 (de) * 1994-03-15 1995-09-21 Hoechst Ag Nichtcyclische Chelatbildner auf Basis von Aminodialkylphosphoroxiden zur Herstellung von Technetium- oder Rheniumkomplexen
US6001229A (en) * 1994-08-01 1999-12-14 Lockheed Martin Energy Systems, Inc. Apparatus and method for performing microfluidic manipulations for chemical analysis
ATE194143T1 (de) * 1996-08-28 2000-07-15 Immunomedics Inc Stabile radioiodium-konjugate und verfahren zu deren herstellung
AU738237B2 (en) * 1997-07-22 2001-09-13 Qiagen Genomics, Inc. Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques
DE19840489A1 (de) * 1998-09-04 2000-03-09 Basf Ag Wirkstoffzubereitungen sowie ein Verfahren zu deren Herstellung

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11510595A (ja) * 1995-06-07 1999-09-14 バイオセプラ，インコーポレイテッド 螢光分光光度計測による流体中の所期の溶質のオンライン検出

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN5006020056, ＳＰＩＫＭＡＮＳ ＶＡＬＥＲＩＥ, ＲＡＰＩＤ ＣＯＭＭＵＮＩＣＡＴＩＯＮＳ ＩＮ ＭＡＳＳ ＳＰＥＣＴＲＯＭＥＴＲＹ ： ＲＣＭ, 2002, Ｖ１６ Ｎ１４, Ｐ１３７７−１３８８ *

Also Published As

Publication number Publication date
DE10350484B4 (de) 2006-02-02
WO2005064335A2 (de) 2005-07-14
WO2005064335A3 (de) 2005-09-22
US20080058506A1 (en) 2008-03-06
EP1697747B1 (de) 2008-12-03
EP1697747A2 (de) 2006-09-06
ATE416382T1 (de) 2008-12-15
DE502004008602D1 (de) 2009-01-15
DE10350484A1 (de) 2005-07-28

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