JP2007517047A - 腸溶コーティングされた脂肪族アミンポリマーの胆汁酸捕捉因子 - Google Patents

腸溶コーティングされた脂肪族アミンポリマーの胆汁酸捕捉因子 Download PDF

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Publication number
JP2007517047A
JP2007517047A JP2006547440A JP2006547440A JP2007517047A JP 2007517047 A JP2007517047 A JP 2007517047A JP 2006547440 A JP2006547440 A JP 2006547440A JP 2006547440 A JP2006547440 A JP 2006547440A JP 2007517047 A JP2007517047 A JP 2007517047A
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Japan
Prior art keywords
tablet
aliphatic amine
core
enteric coating
amine polymer
Prior art date
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Withdrawn
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JP2006547440A
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English (en)
Japanese (ja)
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JP2007517047A5 (enExample
Inventor
ヒテシュ アール． バガト，
ジョアン エム． ドノバン，
ウィリアム ブラウンリン，
ロバート サッキエロ，
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Genzyme Corp
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Genzyme Corp
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Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of JP2007517047A publication Critical patent/JP2007517047A/ja
Publication of JP2007517047A5 publication Critical patent/JP2007517047A5/ja
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2006547440A 2003-12-31 2004-12-23 腸溶コーティングされた脂肪族アミンポリマーの胆汁酸捕捉因子 Withdrawn JP2007517047A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53356303P 2003-12-31 2003-12-31
PCT/US2004/043537 WO2005065291A2 (en) 2003-12-31 2004-12-23 Enteric coated aliphatic amine polymer bile acid sequestrants

Publications (2)

Publication Number Publication Date
JP2007517047A true JP2007517047A (ja) 2007-06-28
JP2007517047A5 JP2007517047A5 (enExample) 2008-01-24

Family

ID=34748918

Family Applications (1)

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JP2006547440A Withdrawn JP2007517047A (ja) 2003-12-31 2004-12-23 腸溶コーティングされた脂肪族アミンポリマーの胆汁酸捕捉因子

Country Status (6)

Country Link
US (1) US20070098678A1 (enExample)
EP (1) EP1699442A2 (enExample)
JP (1) JP2007517047A (enExample)
AU (1) AU2004311849B2 (enExample)
CA (1) CA2551528A1 (enExample)
WO (1) WO2005065291A2 (enExample)

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US7429394B2 (en) 2004-03-30 2008-09-30 Relypsa, Inc. Ion binding compositions
US7854924B2 (en) 2004-03-30 2010-12-21 Relypsa, Inc. Methods and compositions for treatment of ion imbalances
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US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
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US8986669B2 (en) * 2005-09-02 2015-03-24 Genzyme Corporation Method for removing phosphate and polymer used therefore
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AU2012205214B2 (en) * 2005-09-15 2015-05-21 Genzyme Corporation Formulation for Amine Polymers
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CA2626734A1 (en) * 2005-11-08 2007-05-18 Genzyme Corporation Magnesium-containing polymers for the treatment of hyperphosphatemia
EP2016114A2 (en) * 2006-05-05 2009-01-21 Genzyme Corporation Amine condensation polymers as phosphate sequestrants
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EP2066293A2 (en) 2006-09-29 2009-06-10 Genzyme Corporation Amide dendrimer compositions
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US20100129309A1 (en) * 2007-02-23 2010-05-27 Dhal Pradeep K Amine polymer compositions
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JP2010525061A (ja) * 2007-04-27 2010-07-22 ゲンズイメ コーポレーション アミドアミンデンドリマー組成物
US20100316589A1 (en) * 2007-12-14 2010-12-16 Hitesh Bhagat Coated Pharmaceutical Compositions
US20110142952A1 (en) * 2008-06-20 2011-06-16 Harris David J Pharmaceutical Compositions
DE102008030046A1 (de) * 2008-06-25 2009-12-31 Ratiopharm Gmbh Kompaktiertes Polyallylamin-Polymer
US8337824B2 (en) 2008-08-22 2012-12-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
US20110159087A1 (en) * 2008-09-02 2011-06-30 Dhananjay Govind Sathe Crosslinked Polymers
US9655920B2 (en) 2010-02-24 2017-05-23 Relypsa, Inc. Amine polymers for use as bile acid sequestrants
CN119405686A (zh) 2012-10-08 2025-02-11 维福(国际)有限公司 治疗高血压和高血钾症的钾结合剂
HRP20171590T1 (hr) 2013-06-05 2017-12-29 Tricida Inc. Polimeri koji vežu protone za oralnu primjenu
JP2017517550A (ja) 2014-06-13 2017-06-29 ユナイテッド セラピューティクス コーポレイション トレプロスチニル製剤
PL3229816T3 (pl) 2014-12-10 2020-09-21 Tricida Inc. Polimery wiążące protony do podawania doustnego
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
US10245284B2 (en) 2015-08-19 2019-04-02 Alpex Pharma S.A. Granular composition for oral administration
US20190105277A1 (en) * 2016-04-05 2019-04-11 Pharmathen S.A. Pharmaceutical composition comprising an atypical antipsychotic agent and method for the preparation thereof
EP3452028A4 (en) 2016-05-06 2020-04-15 Tricida Inc. COMPOSITIONS AND METHOD FOR TREATING ACID-BASED DISORDERS
CN106405028A (zh) * 2016-10-10 2017-02-15 方达医药技术（苏州）有限公司 溶出仪在评价碳酸司维拉姆片生物等效中的应用
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US11590161B2 (en) 2018-08-13 2023-02-28 Viscera Labs, Inc. Therapeutic composition and methods
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Also Published As

Publication number Publication date
US20070098678A1 (en) 2007-05-03
WO2005065291A3 (en) 2006-02-09
AU2004311849A1 (en) 2005-07-21
AU2004311849B2 (en) 2009-04-02
WO2005065291A2 (en) 2005-07-21
EP1699442A2 (en) 2006-09-13
CA2551528A1 (en) 2005-07-21

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