AU2004311849B2 - Enteric coated aliphatic amine polymer bile acid sequestrants - Google Patents

Enteric coated aliphatic amine polymer bile acid sequestrants Download PDF

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Publication number
AU2004311849B2
AU2004311849B2 AU2004311849A AU2004311849A AU2004311849B2 AU 2004311849 B2 AU2004311849 B2 AU 2004311849B2 AU 2004311849 A AU2004311849 A AU 2004311849A AU 2004311849 A AU2004311849 A AU 2004311849A AU 2004311849 B2 AU2004311849 B2 AU 2004311849B2
Authority
AU
Australia
Prior art keywords
tablet
aliphatic amine
enteric coating
amine polymer
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2004311849A
Other languages
English (en)
Other versions
AU2004311849A1 (en
Inventor
Hitesh R. Bhagat
William Braunlin
Joanne M. Donovan
Robert Sacchiero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genzyme Corp
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of AU2004311849A1 publication Critical patent/AU2004311849A1/en
Application granted granted Critical
Publication of AU2004311849B2 publication Critical patent/AU2004311849B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2004311849A 2003-12-31 2004-12-23 Enteric coated aliphatic amine polymer bile acid sequestrants Ceased AU2004311849B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53356303P 2003-12-31 2003-12-31
US60/533,563 2003-12-31
PCT/US2004/043537 WO2005065291A2 (en) 2003-12-31 2004-12-23 Enteric coated aliphatic amine polymer bile acid sequestrants

Publications (2)

Publication Number Publication Date
AU2004311849A1 AU2004311849A1 (en) 2005-07-21
AU2004311849B2 true AU2004311849B2 (en) 2009-04-02

Family

ID=34748918

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004311849A Ceased AU2004311849B2 (en) 2003-12-31 2004-12-23 Enteric coated aliphatic amine polymer bile acid sequestrants

Country Status (6)

Country Link
US (1) US20070098678A1 (enExample)
EP (1) EP1699442A2 (enExample)
JP (1) JP2007517047A (enExample)
AU (1) AU2004311849B2 (enExample)
CA (1) CA2551528A1 (enExample)
WO (1) WO2005065291A2 (enExample)

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US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7449605B2 (en) 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7385012B2 (en) 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7459502B2 (en) 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7556799B2 (en) 2004-03-30 2009-07-07 Relypsa, Inc. Ion binding polymers and uses thereof
US8192758B2 (en) 2004-03-30 2012-06-05 Relypsa, Inc. Ion binding compositions
US7429394B2 (en) 2004-03-30 2008-09-30 Relypsa, Inc. Ion binding compositions
US8282960B2 (en) 2004-03-30 2012-10-09 Relypsa, Inc. Ion binding compositions
US7854924B2 (en) 2004-03-30 2010-12-21 Relypsa, Inc. Methods and compositions for treatment of ion imbalances
EP1732523B9 (en) 2004-03-30 2010-06-02 Relypsa, Inc. Potassium binding polymers and uses thereof
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
US7522961B2 (en) 2004-11-17 2009-04-21 Advanced Bionics, Llc Inner hair cell stimulation model for the use by an intra-cochlear implant
EP1830832A1 (en) * 2004-12-30 2007-09-12 Genzyme Corporation Zinc-containing treatments for hyperphosphatemia
EP1951266A2 (en) * 2005-09-02 2008-08-06 Genzyme Corporation Method for removing phosphate and polymer used therefore
AU2012205214B2 (en) * 2005-09-15 2015-05-21 Genzyme Corporation Formulation for Amine Polymers
KR101547925B1 (ko) * 2005-09-15 2015-08-27 젠자임 코포레이션 아민 중합체에 대한 샤셋 제형
KR20080059265A (ko) 2005-09-30 2008-06-26 일립사, 인코포레이티드 포유동물의 위장관으로부터 칼륨 이온을 선택적으로제거하기 위한 방법 및 조성물
US8586097B2 (en) 2005-09-30 2013-11-19 Relypsa, Inc. Methods for preparing core-shell composites having cross-linked shells and core-shell composites resulting therefrom
US20090162314A1 (en) * 2005-11-08 2009-06-25 Huval Chad C Magnesium-Containing Polymers for the Treatment of Hyperphosphatemia
JP2009536246A (ja) * 2006-05-05 2009-10-08 ゲンズイメ コーポレーション ホスフェート捕捉剤としてのアミン縮合重合体
JP2009542653A (ja) * 2006-07-05 2009-12-03 ジェンザイム コーポレーション リン酸塩過剰血症のための鉄（ｉｉ）含有治療剤
MX2009000611A (es) * 2006-07-18 2009-04-16 Genzyme Corp Dendrimeros de amina.
EP2066293A2 (en) 2006-09-29 2009-06-10 Genzyme Corporation Amide dendrimer compositions
WO2008076242A1 (en) * 2006-12-14 2008-06-26 Genzyme Corporation Amido-amine polymer compositions
JP2010519298A (ja) * 2007-02-23 2010-06-03 ゲンズイメ コーポレーション アミンポリマー組成物
EP2131820A1 (en) * 2007-03-08 2009-12-16 Genzyme Corporation Sulfone polymer compositions
WO2008133954A1 (en) * 2007-04-27 2008-11-06 Genzyme Corporation Amido-amine dendrimer compositions
EP2217215A1 (en) * 2007-12-14 2010-08-18 Genzyme Corporation Coated pharmaceutical compositions
US20110142952A1 (en) * 2008-06-20 2011-06-16 Harris David J Pharmaceutical Compositions
DE102008030046A1 (de) * 2008-06-25 2009-12-31 Ratiopharm Gmbh Kompaktiertes Polyallylamin-Polymer
US8337824B2 (en) 2008-08-22 2012-12-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
CA2735962A1 (en) * 2008-09-02 2010-04-15 Usv Limited Crosslinked polymers
EP2539389B1 (en) 2010-02-24 2017-12-20 Relypsa, Inc. Amine polymers for use as bile acid sequestrants
EP2916851B1 (en) 2012-10-08 2025-12-17 Vifor (International) Ltd. Potassium-binding agents for treating hypertension and hyperkalemia
KR102633597B1 (ko) 2013-06-05 2024-02-06 트리시다, 인크. 경구 투여를 위한 양성자-결합 중합체
US20170095432A1 (en) 2014-06-13 2017-04-06 United Therapeutics Corporation Treprostinil formulations
KR20240008418A (ko) 2014-12-10 2024-01-18 트리시다, 인크. 경구 투여용 양성자-결합 폴리머
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
US10245284B2 (en) 2015-08-19 2019-04-02 Alpex Pharma S.A. Granular composition for oral administration
US20190105277A1 (en) * 2016-04-05 2019-04-11 Pharmathen S.A. Pharmaceutical composition comprising an atypical antipsychotic agent and method for the preparation thereof
AU2017261337A1 (en) 2016-05-06 2018-11-15 Tricida, Inc. Compositions for and method of treating acid-base disorders
CN106405028A (zh) * 2016-10-10 2017-02-15 方达医药技术（苏州）有限公司 溶出仪在评价碳酸司维拉姆片生物等效中的应用
US11266684B2 (en) 2017-11-03 2022-03-08 Tricida, Inc. Compositions for and method of treating acid-base disorders
US11524029B2 (en) 2018-08-13 2022-12-13 Viscera Labs, Inc. Therapeutic composition and methods
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WO2021163007A1 (en) * 2020-02-12 2021-08-19 Viscera Labs, Inc. Therapeutic composition and methods
EP4295836A1 (en) * 2022-06-22 2023-12-27 Labomed Pharmaceutical Company S.A. Sachet comprising a liquid suspension of a sevelamer salt
CN119564718A (zh) * 2023-11-30 2025-03-07 成都施桂行医药科技有限责任公司 靶向回肠递送内毒素螯合剂药物及其制备方法和应用
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WO1994028881A1 (en) * 1993-06-11 1994-12-22 Merix Corporation Delayed release and trapping formulation for a bile acid adsorbent
EP0637447A2 (en) * 1993-08-03 1995-02-08 Mitsubishi Chemical Corporation Orally administrable cholesterol lowering agent
EP0922461A1 (en) * 1996-07-19 1999-06-16 Nikken Chemicals Company, Limited Remedies for hyperphosphatemia
WO2001028527A2 (en) * 1999-10-19 2001-04-26 Geltex Pharmaceuticals, Inc. Direct compression polymer tablet core
WO2001060392A1 (en) * 2000-02-18 2001-08-23 Yeda Research And Development Co., Ltd. At The Weizmann Institute Of Science Oral, nasal and pulmonary dosage formualtions of copolymer 1

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US6733780B1 (en) * 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
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Patent Citations (6)

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WO1993000915A1 (en) * 1991-07-03 1993-01-21 The Upjohn Company Colestipol hydrochloride high-content tablets
WO1994028881A1 (en) * 1993-06-11 1994-12-22 Merix Corporation Delayed release and trapping formulation for a bile acid adsorbent
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EP0922461A1 (en) * 1996-07-19 1999-06-16 Nikken Chemicals Company, Limited Remedies for hyperphosphatemia
WO2001028527A2 (en) * 1999-10-19 2001-04-26 Geltex Pharmaceuticals, Inc. Direct compression polymer tablet core
WO2001060392A1 (en) * 2000-02-18 2001-08-23 Yeda Research And Development Co., Ltd. At The Weizmann Institute Of Science Oral, nasal and pulmonary dosage formualtions of copolymer 1

Also Published As

Publication number Publication date
WO2005065291A3 (en) 2006-02-09
US20070098678A1 (en) 2007-05-03
EP1699442A2 (en) 2006-09-13
AU2004311849A1 (en) 2005-07-21
CA2551528A1 (en) 2005-07-21
WO2005065291A2 (en) 2005-07-21
JP2007517047A (ja) 2007-06-28

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired