JP2007514732A - 神経変性過程の予防及び治療のためのテルル誘導体 - Google Patents

神経変性過程の予防及び治療のためのテルル誘導体 Download PDF

Info

Publication number
JP2007514732A
JP2007514732A JP2006544590A JP2006544590A JP2007514732A JP 2007514732 A JP2007514732 A JP 2007514732A JP 2006544590 A JP2006544590 A JP 2006544590A JP 2006544590 A JP2006544590 A JP 2006544590A JP 2007514732 A JP2007514732 A JP 2007514732A
Authority
JP
Japan
Prior art keywords
carbon
compound
cells
teo
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006544590A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007514732A5 (enExample
Inventor
ベンジャミン スレドニ,
マイケル アルベック,
Original Assignee
バイオマス リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by バイオマス リミテッド filed Critical バイオマス リミテッド
Publication of JP2007514732A publication Critical patent/JP2007514732A/ja
Publication of JP2007514732A5 publication Critical patent/JP2007514732A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2006544590A 2003-12-18 2004-12-15 神経変性過程の予防及び治療のためのテルル誘導体 Pending JP2007514732A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53049003P 2003-12-18 2003-12-18
PCT/IB2004/004163 WO2005060341A2 (en) 2003-12-18 2004-12-15 Tellurium derivatives for prevention and treatment of neurodegenerative processes

Publications (2)

Publication Number Publication Date
JP2007514732A true JP2007514732A (ja) 2007-06-07
JP2007514732A5 JP2007514732A5 (enExample) 2008-01-10

Family

ID=34710166

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006544590A Pending JP2007514732A (ja) 2003-12-18 2004-12-15 神経変性過程の予防及び治療のためのテルル誘導体

Country Status (7)

Country Link
US (2) US7629382B2 (enExample)
EP (1) EP1694313A4 (enExample)
JP (1) JP2007514732A (enExample)
AU (1) AU2004304716B2 (enExample)
CA (1) CA2550459C (enExample)
IL (1) IL176333A0 (enExample)
WO (1) WO2005060341A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2550459C (en) 2003-12-18 2009-12-15 Biomas, Ltd. Tellurium derivatives for prevention and treatment of neurodegenerative processes
WO2006030440A2 (en) * 2004-09-17 2006-03-23 Biomas Ltd. Use of tellurium compounds as adjuvants
US7652065B2 (en) * 2004-09-17 2010-01-26 Biomas Ltd. Tellurium compounds and their use as immunomodulators
EP2076274A4 (en) * 2006-09-11 2010-08-04 Biomas Ltd TOPICAL FORMULATIONS OF COMPOUNDS CONTAINING TELLURE
EP2826371B1 (en) * 2007-11-23 2019-01-02 Feramda Ltd. Methods and compositions for inhibiting integrins using tellurium-containing compounds
US20100321208A1 (en) * 2009-06-23 2010-12-23 Craig Stephen Etchegoyen System and Method for Emergency Communications

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07179351A (ja) * 1985-03-15 1995-07-18 Univ Bar Ilan リンホカイン生産刺激剤
WO2003044038A2 (en) * 2001-11-22 2003-05-30 Biomas Ltd. Biologically active complex
JP2003521471A (ja) * 1999-04-08 2003-07-15 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 慢性神経変性疾患を処置することに有用な抗痙攣薬誘導体

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3369550A (en) 1967-02-17 1968-02-20 Thomas A. Armao Cryogenic clamps
GB1427415A (en) 1973-09-21 1976-03-10 Armao T A Cryosurgical instruments
US4962207A (en) 1985-09-30 1990-10-09 Bar-Ilan University Organic derivatives of tellurium and selenium
US5102908A (en) 1985-03-15 1992-04-07 Michael Albeck Method of treating Acquired Immunedeficiency Syndrome (AIDS) using organic tellurium and selenium derivatives
US4752614A (en) 1985-09-30 1988-06-21 Bar-Ilan University Pharmaceutical compositions of tellerium and selenium compounds for the induction of in vivo and in vitro production of cytokines
US5093135A (en) 1985-09-30 1992-03-03 Michael Albeck Compounds for the induction of in vivo and in vitro production of cytokines
US4929739A (en) 1988-03-24 1990-05-29 Bar-Ilan University Complexes of tellurium and selenium derivatives
US5271925A (en) 1990-03-09 1993-12-21 Benjamin Sredni Method for protecting against the effects of radiation which is based on the administration of a selenium or tellurium based compound
DE4007473A1 (de) 1990-03-09 1991-09-12 Tomsk G Med I Kryoskalpell
SE9200502D0 (sv) * 1992-02-20 1992-02-20 Astra Ab Novel antioxidants
US5262149A (en) 1992-08-13 1993-11-16 Benjamin Sredni Method of treating or preventing alopecia
FR2717824B1 (fr) * 1994-03-25 1996-04-26 Rhone Poulenc Rorer Sa Virus recombinants, préparation et utilisation en thérapie génique.
AU696856B2 (en) * 1994-09-01 1998-09-17 Pharmacia & Upjohn Company Cosolvent parenteral formulation of tirilazad
US5576347A (en) 1994-11-14 1996-11-19 Sredni; Benjamin Method of treating gastric ulcers
DE69534535T2 (de) 1994-12-15 2006-07-06 Baker Norton Pharmaceuticals, Inc., Miami Verfahren und mittel zur verminderung der tumorentwicklung mittels einer kombination aus einer taxanverbindung und einer tellur und/oder selenverbindung
US5654328A (en) * 1994-12-15 1997-08-05 Sredni; Benjamin Method and composition for reducing tumor development with a combination of platinum and tellurium or selenium compounds
US6428534B1 (en) 1999-02-24 2002-08-06 Cryovascular Systems, Inc. Cryogenic angioplasty catheter
US6747008B1 (en) 2000-06-19 2004-06-08 University Of Southern California Methods for treating and preventing alopecia
EP1292610A1 (en) 2000-06-19 2003-03-19 University Of Southern California Methods for treating and preventing alopecia
US20030148970A1 (en) 2001-01-12 2003-08-07 Besterman Jeffrey M. Methods for specifically inhibiting histone deacetylase-4
US6472381B1 (en) 2001-10-12 2002-10-29 Biomas Inc. Method of treating psoriasis
WO2004110338A2 (en) * 2003-06-12 2004-12-23 Biomas Ltd. Methods of treating obesity and related disorders using tellurium and selenium compounds
CA2550459C (en) 2003-12-18 2009-12-15 Biomas, Ltd. Tellurium derivatives for prevention and treatment of neurodegenerative processes
US7652065B2 (en) 2004-09-17 2010-01-26 Biomas Ltd. Tellurium compounds and their use as immunomodulators
WO2006030440A2 (en) 2004-09-17 2006-03-23 Biomas Ltd. Use of tellurium compounds as adjuvants

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07179351A (ja) * 1985-03-15 1995-07-18 Univ Bar Ilan リンホカイン生産刺激剤
JP2003521471A (ja) * 1999-04-08 2003-07-15 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 慢性神経変性疾患を処置することに有用な抗痙攣薬誘導体
WO2003044038A2 (en) * 2001-11-22 2003-05-30 Biomas Ltd. Biologically active complex

Also Published As

Publication number Publication date
WO2005060341A2 (en) 2005-07-07
EP1694313A2 (en) 2006-08-30
US7629382B2 (en) 2009-12-08
WO2005060341A3 (en) 2006-09-28
AU2004304716A1 (en) 2005-07-07
CA2550459A1 (en) 2005-07-07
CA2550459C (en) 2009-12-15
IL176333A0 (en) 2006-10-05
AU2004304716B2 (en) 2010-05-27
EP1694313A4 (en) 2010-11-17
US20100062081A1 (en) 2010-03-11
US20060063750A1 (en) 2006-03-23

Similar Documents

Publication Publication Date Title
US8501812B2 (en) Therapeutic methods for type I diabetes
US20200325148A1 (en) Compositions and methods of treatment for neurological disorders comprising motor neuron diseases
WO2002002090A2 (en) Inhibitors of copper-containing amine oxidases
US20100247517A1 (en) Use of mnk inhibitors for the treatment of alzheimer's disease
JP7285599B2 (ja) 筋萎縮性側索硬化症治療剤及び治療用組成物
JP2011088938A (ja) 眼血管新生疾患の処置のためのスタウロスポリン誘導体の使用
JP2024015132A (ja) O-環状フィトスフィンゴシン-1-フォスフェートを含むパーキンソン病の予防又は治療用組成物
PT94713A (pt) Processo para a preparacao de composicoes farmaceuticas contendo um derivado heteroaril-3-oxo-propanonitrilico como ingrediente activo capazes de estimular a mielopoese em mamiferos
JP2007514732A (ja) 神経変性過程の予防及び治療のためのテルル誘導体
TWI306401B (en) Benzothiazolium compounds
CN1183042A (zh) 含有氨甲喋呤衍生物的药剂
JP2022504184A (ja) ブドウ膜黒色腫の治療のための併用療法
KR20040097236A (ko) 신경 교아종 치료제
AU2018309710A1 (en) Methods and compositions for treating neurological conditions
US20050182125A1 (en) Pyrrole compounds and uses thereof
US8664237B2 (en) Spiperone derivatives and methods of treating disorders
WO2021147971A1 (zh) 治疗阿尔茨海默病的化合物
US20250243172A1 (en) Nlrp3 inflammasome inhibitors and compositions and uses thereof
CN103040827A (zh) 神经激肽受体的拮抗剂sr140333在肝癌治疗中的用途
WO2021195185A1 (en) Method of treating coronavirus infection by administration of ethyl mercury or thiol derivative thereof
TW202120082A (zh) 鈣蛋白酶(calpain)抑制劑及其用於治療神經疾病之用途
Chen et al. Effects of overexpression of Hsp70 in neural stem cells on neurotoxicity and cognitive dysfunction in neonatal mice under sevoflurane exposure
US20230302000A1 (en) Combination drug treatment to increase neurogenesis for neurological disorders
US20240165113A1 (en) Methods of treatment for leukemia
CN117919422A (zh) Yoda1在制备治疗肝脏纤维化的药物中的应用

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20071114

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20071114

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110412

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110629

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110706

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110805

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110812

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110909

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110916

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20120106