JP2007513072A5 - - Google Patents
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- Publication number
- JP2007513072A5 JP2007513072A5 JP2006538539A JP2006538539A JP2007513072A5 JP 2007513072 A5 JP2007513072 A5 JP 2007513072A5 JP 2006538539 A JP2006538539 A JP 2006538539A JP 2006538539 A JP2006538539 A JP 2006538539A JP 2007513072 A5 JP2007513072 A5 JP 2007513072A5
- Authority
- JP
- Japan
- Prior art keywords
- medicament
- antibody
- cell
- medicament according
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51777503P | 2003-11-05 | 2003-11-05 | |
| PCT/US2004/037137 WO2005044998A2 (en) | 2003-11-05 | 2004-11-05 | Enhanced b cell cytotoxicity of cdim binding antibody |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007513072A JP2007513072A (ja) | 2007-05-24 |
| JP2007513072A5 true JP2007513072A5 (https=) | 2007-12-20 |
Family
ID=34572964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006538539A Pending JP2007513072A (ja) | 2003-11-05 | 2004-11-05 | Cdim結合抗体における増強されたb細胞細胞傷害性 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20050112130A1 (https=) |
| EP (1) | EP1682179A4 (https=) |
| JP (1) | JP2007513072A (https=) |
| CN (1) | CN1878568A (https=) |
| AU (1) | AU2004288231A1 (https=) |
| BR (1) | BRPI0416243A (https=) |
| CA (1) | CA2542886A1 (https=) |
| IL (1) | IL175318A0 (https=) |
| MX (1) | MXPA06005104A (https=) |
| SG (1) | SG148161A1 (https=) |
| WO (1) | WO2005044998A2 (https=) |
| ZA (1) | ZA200603563B (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000067796A1 (en) | 1999-05-07 | 2000-11-16 | Genentech, Inc. | Treatment of autoimmune diseases with antagonists which bind to b cell surface markers |
| KR20020027490A (ko) * | 1999-07-12 | 2002-04-13 | 제넨테크, 인크. | Cd20에 결합하는 길항제를 사용한 외래 항원에 대한면역 반응 차단 방법 |
| JP2004508420A (ja) * | 2000-09-18 | 2004-03-18 | アイデック ファーマスーティカルズ コーポレイション | B細胞枯渇抗体/免疫調節性抗体の組合せを用いて自己免疫疾患を治療するための併用療法 |
| US6820011B2 (en) | 2001-04-11 | 2004-11-16 | The Regents Of The University Of Colorado | Three-dimensional structure of complement receptor type 2 and uses thereof |
| US7577655B2 (en) * | 2003-09-16 | 2009-08-18 | Google Inc. | Systems and methods for improving the ranking of news articles |
| NZ584288A (en) * | 2004-02-06 | 2011-10-28 | Elan Pharm Inc | Methods and compositions for treating tumors and metastatic disease |
| DK1814913T3 (en) | 2004-11-05 | 2015-09-28 | Univ Leland Stanford Junior | ANTIBODY-INDUCED CELL membrane damage. |
| US20110166319A1 (en) * | 2005-02-11 | 2011-07-07 | Immunogen, Inc. | Process for preparing purified drug conjugates |
| US8293716B2 (en) * | 2005-05-26 | 2012-10-23 | Ramot At Tel Aviv University Ltd. | Method of treating cancer by modulation of mortalin |
| CA3000520C (en) | 2005-08-24 | 2023-04-04 | Immunogen, Inc. | Process for preparing antibody maytansinoid conjugates |
| WO2007030602A2 (en) * | 2005-09-07 | 2007-03-15 | The University Of Iowa Research Foundation | Treatment of b cells with il-21 and b cell activators induces granzyme b production |
| US20070081989A1 (en) * | 2005-09-19 | 2007-04-12 | Sanders Martin E | Treatment of B cell diseases using anti-germline antibody binding agents |
| WO2007059099A2 (en) * | 2005-11-14 | 2007-05-24 | Point Therapeutics, Inc. | Boroproline combination therapy for cancer |
| US8052971B2 (en) * | 2005-11-21 | 2011-11-08 | MG Biologics | Oral use of specific antibodies for intestinal health |
| WO2007092944A2 (en) * | 2006-02-08 | 2007-08-16 | Introgen Therapeutics, Inc. | Compositions and methods involving gene therapy and proteasome modulation |
| US7759304B2 (en) | 2006-06-21 | 2010-07-20 | Regents Of The University Of Colorado | Targeting complement factor H for treatment of diseases |
| WO2008073160A2 (en) * | 2006-08-17 | 2008-06-19 | The Trustees Of Columbia University In The City Of New York | Methods for converting or inducing protective immunity |
| WO2008032324A2 (en) * | 2006-09-14 | 2008-03-20 | Ramot At Tel Aviv University Ltd. | Combination therapy for tumoral disease treatment |
| WO2009040819A2 (en) * | 2007-09-25 | 2009-04-02 | Ramot At Tel Aviv University Ltd. | DOWN-REGULATION OF MORTALIN BY siRNA |
| EP2077281A1 (en) * | 2008-01-02 | 2009-07-08 | Bergen Teknologioverforing AS | Anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome |
| WO2009145831A1 (en) * | 2008-04-02 | 2009-12-03 | Geisinger Clinic | Treatment of the idiopathic nephrotic syndrome spectrum diseases using basiliximab |
| SG10201810743WA (en) | 2009-06-03 | 2018-12-28 | Immunogen Inc | Conjugation methods |
| WO2011003098A1 (en) | 2009-07-02 | 2011-01-06 | Musc Foundation For Research Development | Methods of stimulating liver regeneration |
| CA2795311A1 (en) | 2009-11-05 | 2011-05-12 | Taligen Therapeutics, Inc. | Treatment of paroxysmal nocturnal hemoglobinuria, hemolytic anemias and disease states involving intravascular and extravascular hemolysis |
| BR112012029067A2 (pt) | 2010-05-14 | 2019-09-24 | Univ Colorado Regents | grupos-alvo de receptor do complemento 2 (cr2) melhorados. |
| SG186397A1 (en) | 2010-06-22 | 2013-01-30 | Univ Colorado Regents | Antibodies to the c3d fragment of complement component 3 |
| KR20120093002A (ko) | 2011-02-14 | 2012-08-22 | (주)에이티젠 | Nk 세포의 활성 측정을 이용한 암 진단 방법 및 진단 키트 |
| ME03353B (me) | 2011-03-29 | 2019-10-20 | Immunogen Inc | Priprema konjugata antitela i majtanzinoida jednostepenim postupkom |
| WO2013120012A2 (en) * | 2012-02-08 | 2013-08-15 | Igm Biosciences Inc. | Cdim binding proteins and uses thereof |
| JP2015535212A (ja) | 2012-08-17 | 2015-12-10 | ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・コロラド、ア・ボデイー・コーポレイト | 補体活性化を検出するための組成物および方法 |
| US10413620B2 (en) | 2012-08-17 | 2019-09-17 | The Regents Of The University Of Colorado, A Body Corporate | Light-emitting versions of the monoclonal antibody to C3D (MAB 3D29) for imaging |
| RU2661083C2 (ru) | 2012-10-04 | 2018-07-11 | Иммуноджен, Инк. | Использование пвдф-мембраны для очистки конъюгатов клеточно-связывающий агент - цитотоксический агент |
| EP3052189A4 (en) * | 2013-10-03 | 2017-11-01 | Leuvas Therapeutics | Modulation of leukocyte activity in treatment of neuroinflammatory degenerative disease |
| CA2981077A1 (en) * | 2015-04-03 | 2016-10-06 | Dana-Farber Cancer Institute, Inc. | Composition and methods of genome editing of b-cells |
| GB202011993D0 (en) | 2020-07-31 | 2020-09-16 | Adc Therapeutics Sa | ANTI-IL 13Ra2 antibodies |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5099069A (en) * | 1986-09-05 | 1992-03-24 | Gansow Otto A | Backbone polysubstituted chelates for forming a metal chelate-protein conjugate |
| US4831175A (en) * | 1986-09-05 | 1989-05-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Backbone polysubstituted chelates for forming a metal chelate-protein conjugate |
| US5246692A (en) * | 1986-09-05 | 1993-09-21 | The United States Of America As Represented By The Secretary Of Health And Human Services | Backbone polysubstituted chelates for forming a metal chelate-protein conjugate |
| FR2626882B1 (fr) * | 1988-02-08 | 1991-11-08 | Ire Celltarg Sa | Conjugues de derives de vinca comportant une chaine detergente en position c-3 |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US5460785A (en) * | 1989-08-09 | 1995-10-24 | Rhomed Incorporated | Direct labeling of antibodies and other protein with metal ions |
| US5208020A (en) * | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
| US5124471A (en) * | 1990-03-26 | 1992-06-23 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Bifunctional dtpa-type ligand |
| ATE207080T1 (de) | 1991-11-25 | 2001-11-15 | Enzon Inc | Multivalente antigen-bindende proteine |
| US5521184A (en) | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
| US6765087B1 (en) | 1992-08-21 | 2004-07-20 | Vrije Universiteit Brussel | Immunoglobulins devoid of light chains |
| DK1621554T4 (da) | 1992-08-21 | 2012-12-17 | Univ Bruxelles | Immunoglobuliner blottet for lette kæder |
| AU5361794A (en) * | 1992-10-14 | 1994-05-09 | Board Of Trustees Of The Leland Stanford Junior University | Enhancement of b cell lymphoma tumor resistance using idiotype/cytokine conjugates |
| DK0752248T3 (da) | 1992-11-13 | 2000-11-13 | Idec Pharma Corp | Terapeutisk anvendelse af kimæriske og radioaktivt mærkede antistoffer mod humant B-lymfocytbegrænset differentieringsantig |
| US5736137A (en) | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
| US5484892A (en) * | 1993-05-21 | 1996-01-16 | Dana-Farber Cancer Institute, Inc. | Monoclonal antibodies that block ligand binding to the CD22 receptor in mature B cells |
| US5417972A (en) * | 1993-08-02 | 1995-05-23 | The Board Of Trustees Of The Leland Stanford Junior University | Method of killing B-cells in a complement independent and an ADCC independent manner using antibodies which specifically bind CDIM |
| DE69534530T2 (de) * | 1994-08-12 | 2006-07-06 | Immunomedics, Inc. | Für b-zell-lymphom und leukämiezellen spezifische immunkonjugate und humane antikörper |
| US6083903A (en) * | 1994-10-28 | 2000-07-04 | Leukosite, Inc. | Boronic ester and acid compounds, synthesis and uses |
| US6962979B1 (en) | 1995-03-14 | 2005-11-08 | Cohesion Technologies, Inc. | Crosslinkable biomaterial compositions containing hydrophobic and hydrophilic crosslinking agents |
| US5855911A (en) | 1995-08-29 | 1999-01-05 | Board Of Regents, The University Of Texas System | Liposomal phosphodiester, phosphorothioate, and P-ethoxy oligonucleotides |
| US5776746A (en) * | 1996-05-01 | 1998-07-07 | Genitope Corporation | Gene amplification methods |
| US20040136951A1 (en) * | 1997-03-17 | 2004-07-15 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
| US6306393B1 (en) * | 1997-03-24 | 2001-10-23 | Immunomedics, Inc. | Immunotherapy of B-cell malignancies using anti-CD22 antibodies |
| ES2203916T3 (es) * | 1997-09-17 | 2004-04-16 | Ciba Specialty Chemicals Holding Inc. | Aditivo antimicrobiano para detergentes. |
| US6680335B2 (en) | 1998-09-28 | 2004-01-20 | Sugen, Inc. | Methods of modulating protein tyrosine kinase function with substituted indolinone compounds |
| JP2003509428A (ja) | 1999-09-17 | 2003-03-11 | アボツト・ゲー・エム・ベー・ハー・ウント・コンパニー・カーゲー | 治療薬としてのピラゾロピリミジン |
| WO2001074388A1 (en) * | 2000-03-31 | 2001-10-11 | Idec Pharmaceuticals Corporation | Combined use of anti-cytokine antibodies or antagonists and anti-cd20 for the treatment of b cell lymphoma |
| JP2004512262A (ja) * | 2000-06-20 | 2004-04-22 | アイデック ファーマスーティカルズ コーポレイション | 非放射性抗cd20抗体/放射標識抗cd22抗体の組合せ |
| US7113996B2 (en) * | 2000-07-21 | 2006-09-26 | Sandy Craig Kronenberg | Method and system for secured transport and storage of data on a network |
| WO2002096948A2 (en) | 2001-01-29 | 2002-12-05 | Idec Pharmaceuticals Corporation | Engineered tetravalent antibodies and methods of use |
| US6441163B1 (en) | 2001-05-31 | 2002-08-27 | Immunogen, Inc. | Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents |
| US6645974B2 (en) | 2001-07-31 | 2003-11-11 | Merck & Co., Inc. | Androgen receptor modulators and methods for use thereof |
-
2004
- 2004-11-05 CN CNA200480032401XA patent/CN1878568A/zh active Pending
- 2004-11-05 WO PCT/US2004/037137 patent/WO2005044998A2/en not_active Ceased
- 2004-11-05 CA CA002542886A patent/CA2542886A1/en not_active Abandoned
- 2004-11-05 SG SG200808234-9A patent/SG148161A1/en unknown
- 2004-11-05 JP JP2006538539A patent/JP2007513072A/ja active Pending
- 2004-11-05 US US10/982,698 patent/US20050112130A1/en not_active Abandoned
- 2004-11-05 BR BRPI0416243-9A patent/BRPI0416243A/pt not_active IP Right Cessation
- 2004-11-05 AU AU2004288231A patent/AU2004288231A1/en not_active Abandoned
- 2004-11-05 EP EP04810496A patent/EP1682179A4/en not_active Withdrawn
- 2004-11-05 MX MXPA06005104A patent/MXPA06005104A/es not_active Application Discontinuation
-
2006
- 2006-04-30 IL IL175318A patent/IL175318A0/en unknown
- 2006-05-04 ZA ZA200603563A patent/ZA200603563B/en unknown
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