JP2007508343A - 化学療法又は放射線療法の副作用に対する栄養組成物 - Google Patents
化学療法又は放射線療法の副作用に対する栄養組成物 Download PDFInfo
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- JP2007508343A JP2007508343A JP2006534683A JP2006534683A JP2007508343A JP 2007508343 A JP2007508343 A JP 2007508343A JP 2006534683 A JP2006534683 A JP 2006534683A JP 2006534683 A JP2006534683 A JP 2006534683A JP 2007508343 A JP2007508343 A JP 2007508343A
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- nutritional composition
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
Abstract
Description
第一の面において、本発明は、蛋白質供給源、脂質供給源及び炭水化物供給源を含有する、ml当り少なくとも1.3kcalのエネルギー含量を有する栄養組成物であり、蛋白質供給源が、前記組成物のエネルギーの20−30%を提供し、40−80重量%のカゼイン及び60−20重量%のホエーを含有し、前記組成物の100kcal当り0.5−20μgのTGF−βを含有し、前記組成物のエネルギーの2−15%を提供するような量で遊離グルタミンを含有する、栄養組成物を提供する。
本明細書の文脈において、「を含有する」という用語は、「他のものと共に、含む」を意味すると解釈する。本用語は、「のみから成る」と解釈されることを意図しない。
(1)Raftilose(登録商標)の種々の異なる商品名でベルギーの“Orafti”から市販されている、イヌリン(上記参照)の加水分解物、
(2)日本の明治製菓株式会社から市販されているアスペルギルス・ニガーからのβ−フルクトフラノシダーゼを用いての蔗糖からの合成による方法、
において得られる。後者の方法は、5より多い果糖単糖類単位の少糖類を生成しない(いわゆる短鎖、SC FOS)。
表1に記載した成分を用いて粉末栄養組成物を調製する。
Claims (11)
- 蛋白質供給源、脂質供給源及び炭水化物供給源を含有する、ml当り少なくとも1.3kcalのエネルギー含量を有する栄養組成物であり、蛋白質供給源が、
前記組成物のエネルギーの20−30%を提供し、
40−80重量%のカゼイン及び60−20重量%のホエーを含有し、
前記組成物の100kcal当り0.5−20μgのTGF−βを含有し、
前記組成物のエネルギーの2−15%を提供するような量で遊離グルタミンを含有する、栄養組成物。 - TGF−βが、酸カゼインにより供給されるTGF−β2であり、蛋白質供給源のカゼイン成分が、TGF−β2を供給するのに少なくとも十分な酸カゼインを含有する、請求項1又は請求項2に記載の栄養組成物。
- 栄養組成物が、100kcal当り1.5−4μgのTGF−β2を含有する、請求項2に記載の栄養組成物。
- エネルギー含量が1.2−2kcal/mlである、請求項1−3のいずれか1請求項に記載の栄養組成物。
- 遊離グルタミンが、栄養組成物のエネルギーの5−10%を提供する、請求項1−4のいずれか1請求項に記載の栄養組成物。
- 脂質供給源が、栄養組成物のエネルギーの25−45%を提供する、請求項1−5のいずれか1請求項に記載の栄養組成物。
- 脂質供給源が、脂質供給源の重量%で30−70%の中鎖トリグリセリドを含有する、請求項1−6のいずれか1請求項に記載の栄養組成物。
- 炭水化物供給源が、栄養組成物のエネルギーの25−55%を提供する、請求項1−7のいずれか1請求項に記載の栄養組成物。
- 化学療法及び/又は放射線療法の副作用を緩和する及び/又は軽減するための栄養調合物又は栄養補給物の製造における、請求項1−8のいずれか1請求項に記載の組成物の使用。
- 化学療法及び/又は放射線療法の副作用が、下痢、口内炎、粘膜炎及び増大された腸管透過性を含む、請求項9に記載の使用。
- 癌を患っている患者に、化学療法及び/又は放射線療法の治療の期間中及びそのような治療期間の直後に栄養を与えるための栄養調合物又は栄養補給物の製造における、請求項1−8のいずれか1請求項に記載の栄養組成物の使用。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03023383 | 2003-10-16 | ||
EP03023383.7 | 2003-10-16 | ||
PCT/EP2004/011539 WO2005039318A1 (en) | 2003-10-16 | 2004-10-14 | Nutritional composition against side effects of chemotherapy of radiotherapy |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012117592A Division JP2012211139A (ja) | 2003-10-16 | 2012-05-23 | 化学療法又は放射線療法の副作用に対する栄養組成物 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2007508343A true JP2007508343A (ja) | 2007-04-05 |
JP5473190B2 JP5473190B2 (ja) | 2014-04-16 |
Family
ID=34354470
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006534683A Expired - Fee Related JP5473190B2 (ja) | 2003-10-16 | 2004-10-14 | 化学療法又は放射線療法の副作用に対する栄養組成物 |
JP2012117592A Pending JP2012211139A (ja) | 2003-10-16 | 2012-05-23 | 化学療法又は放射線療法の副作用に対する栄養組成物 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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JP2012117592A Pending JP2012211139A (ja) | 2003-10-16 | 2012-05-23 | 化学療法又は放射線療法の副作用に対する栄養組成物 |
Country Status (14)
Country | Link |
---|---|
US (1) | US7468193B2 (ja) |
EP (1) | EP1675480B1 (ja) |
JP (2) | JP5473190B2 (ja) |
CN (1) | CN1889856B (ja) |
AR (1) | AR046184A1 (ja) |
BR (1) | BRPI0415480B1 (ja) |
CA (1) | CA2542652C (ja) |
CO (1) | CO5690615A2 (ja) |
ES (1) | ES2677868T3 (ja) |
IL (1) | IL175081A0 (ja) |
MY (1) | MY148289A (ja) |
TW (1) | TW200526134A (ja) |
WO (1) | WO2005039318A1 (ja) |
ZA (1) | ZA200603886B (ja) |
Cited By (4)
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JP2010526873A (ja) * | 2007-05-14 | 2010-08-05 | フォンテラ コ−オペレイティブ グループ リミティド | 免疫又は血液学的増強、腫瘍の形成又は成長の阻害、及び、癌、癌症状又は癌治療の症状の治療又は予防の方法 |
JP2011511070A (ja) * | 2008-02-07 | 2011-04-07 | ネステク ソシエテ アノニム | 激しい身体活動からの回復に影響を及ぼすための組成物及び方法 |
JP2011201842A (ja) * | 2010-03-26 | 2011-10-13 | Kobayashi Pharmaceutical Co Ltd | 腸由来細胞の増殖促進剤 |
WO2012121095A1 (ja) * | 2011-03-04 | 2012-09-13 | キユーピー 株式会社 | 経腸栄養剤 |
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BR112017022506A2 (pt) | 2015-05-14 | 2018-07-17 | Professional Dietetics S.P.A. | composições compreendendo aminoácidos para uso no tratamento de mucosites em pacientes com neoplasia submetidos a terapia de radiação e / ou quimioterapia |
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JP2010526873A (ja) * | 2007-05-14 | 2010-08-05 | フォンテラ コ−オペレイティブ グループ リミティド | 免疫又は血液学的増強、腫瘍の形成又は成長の阻害、及び、癌、癌症状又は癌治療の症状の治療又は予防の方法 |
JP2011511070A (ja) * | 2008-02-07 | 2011-04-07 | ネステク ソシエテ アノニム | 激しい身体活動からの回復に影響を及ぼすための組成物及び方法 |
US10624937B2 (en) | 2008-02-07 | 2020-04-21 | Societe Des Produits Nestle Sa | Compositions and methods for influencing recovery from strenuous physical activity |
JP2011201842A (ja) * | 2010-03-26 | 2011-10-13 | Kobayashi Pharmaceutical Co Ltd | 腸由来細胞の増殖促進剤 |
WO2012121095A1 (ja) * | 2011-03-04 | 2012-09-13 | キユーピー 株式会社 | 経腸栄養剤 |
JP5824509B2 (ja) * | 2011-03-04 | 2015-11-25 | キユーピー株式会社 | 経腸栄養剤 |
Also Published As
Publication number | Publication date |
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BRPI0415480A (pt) | 2006-12-26 |
JP2012211139A (ja) | 2012-11-01 |
CA2542652C (en) | 2014-05-13 |
MY148289A (en) | 2013-03-29 |
TW200526134A (en) | 2005-08-16 |
EP1675480A1 (en) | 2006-07-05 |
JP5473190B2 (ja) | 2014-04-16 |
BRPI0415480B1 (pt) | 2019-09-17 |
CN1889856B (zh) | 2011-03-02 |
ZA200603886B (en) | 2007-11-28 |
WO2005039318A1 (en) | 2005-05-06 |
CA2542652A1 (en) | 2005-05-06 |
US20070042021A1 (en) | 2007-02-22 |
US7468193B2 (en) | 2008-12-23 |
CN1889856A (zh) | 2007-01-03 |
EP1675480B1 (en) | 2018-06-13 |
CO5690615A2 (es) | 2006-10-31 |
IL175081A0 (en) | 2006-08-20 |
AR046184A1 (es) | 2005-11-30 |
ES2677868T3 (es) | 2018-08-07 |
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