JP2007506679A5 - - Google Patents

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Publication number
JP2007506679A5
JP2007506679A5 JP2006527053A JP2006527053A JP2007506679A5 JP 2007506679 A5 JP2007506679 A5 JP 2007506679A5 JP 2006527053 A JP2006527053 A JP 2006527053A JP 2006527053 A JP2006527053 A JP 2006527053A JP 2007506679 A5 JP2007506679 A5 JP 2007506679A5
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JP
Japan
Prior art keywords
methoxy
methyl
group
oxo
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006527053A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007506679A (ja
JP4717815B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/030484 external-priority patent/WO2005030726A1/en
Publication of JP2007506679A publication Critical patent/JP2007506679A/ja
Publication of JP2007506679A5 publication Critical patent/JP2007506679A5/ja
Application granted granted Critical
Publication of JP4717815B2 publication Critical patent/JP4717815B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2006527053A 2003-09-23 2004-09-17 イソキノリノンカリウムチャネル阻害剤 Expired - Fee Related JP4717815B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50521503P 2003-09-23 2003-09-23
US60/505,215 2003-09-23
PCT/US2004/030484 WO2005030726A1 (en) 2003-09-23 2004-09-17 Isoquinolinone potassium channel inhibitors

Publications (3)

Publication Number Publication Date
JP2007506679A JP2007506679A (ja) 2007-03-22
JP2007506679A5 true JP2007506679A5 (cg-RX-API-DMAC7.html) 2007-10-25
JP4717815B2 JP4717815B2 (ja) 2011-07-06

Family

ID=34392991

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006527053A Expired - Fee Related JP4717815B2 (ja) 2003-09-23 2004-09-17 イソキノリノンカリウムチャネル阻害剤

Country Status (9)

Country Link
US (1) US7741322B2 (cg-RX-API-DMAC7.html)
EP (1) EP1667976B1 (cg-RX-API-DMAC7.html)
JP (1) JP4717815B2 (cg-RX-API-DMAC7.html)
CN (1) CN1856472A (cg-RX-API-DMAC7.html)
AT (1) ATE476419T1 (cg-RX-API-DMAC7.html)
AU (1) AU2004276238B2 (cg-RX-API-DMAC7.html)
CA (1) CA2539729C (cg-RX-API-DMAC7.html)
DE (1) DE602004028493D1 (cg-RX-API-DMAC7.html)
WO (1) WO2005030726A1 (cg-RX-API-DMAC7.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4719151B2 (ja) * 2003-09-23 2011-07-06 メルク・シャープ・エンド・ドーム・コーポレイション イソキノリノンカリウムチャネル阻害剤
WO2005030729A1 (en) * 2003-09-23 2005-04-07 Merck & Co., Inc. Isoquinoline potassium channel inhibitors
EP1667982B1 (en) * 2003-09-23 2013-07-31 Merck Sharp & Dohme Corp. Isoquinolinone potassium channel inhibitors
CA2539541C (en) * 2003-09-23 2010-06-29 Merck & Co., Inc. Isoquinolinone potassium channel inhibitors
US7569589B2 (en) 2004-07-29 2009-08-04 Merck & Co., Inc. Potassium channel inhibitors
CA2575003C (en) 2004-07-29 2010-02-16 Merck & Co., Inc. Potassium channel inhibitors
US7915410B2 (en) 2005-09-09 2011-03-29 Bristol-Myers Squibb Company Acyclic IKur inhibitors
WO2007109577A1 (en) * 2006-03-17 2007-09-27 Kalypsys, Inc. Alkylamine-substituted bicyclic aryl compounds useful as modulators of ppar
DE102006019589A1 (de) * 2006-04-27 2007-10-31 Sanofi-Aventis Deutschland Gmbh Inhibitoren des TASK-1 und Task-3 Ionenkanals
US9623021B2 (en) * 2007-01-22 2017-04-18 Gtx, Inc. Nuclear receptor binding agents
MX2009007831A (es) 2007-01-22 2010-01-15 Gtx Inc Agentes de union de receptor nuclear.
US9604931B2 (en) 2007-01-22 2017-03-28 Gtx, Inc. Nuclear receptor binding agents
CA3072648A1 (en) * 2017-08-14 2019-02-21 Acesion Pharma Aps Substituted benzimidazoles as potassium channel inhibitors
CN110670090B (zh) * 2019-11-13 2021-06-29 广西师范大学 一种基于电化学合成异喹啉酮类化合物的方法
AU2023220657A1 (en) * 2022-02-16 2024-08-08 Duke Street Bio Limited Pharmaceutical compound

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3594380A (en) * 1969-02-18 1971-07-20 American Home Prod Isoquinolin-1(2h)-ones
EP0585913B1 (en) * 1992-09-04 1997-12-29 Takeda Chemical Industries, Ltd. Condensed heterocyclic compounds, their production and use
EP0634402A1 (en) * 1993-07-14 1995-01-18 Takeda Chemical Industries, Ltd. Isochinolinone derivatives, their production and use
US5387685A (en) 1993-07-16 1995-02-07 American Cyanamid Co MDR reversal agents
US6870055B2 (en) 2000-09-20 2005-03-22 Merck & Co., Inc. Isoquinolinone potassium channels inhibitors
WO2002094790A1 (en) * 2001-05-23 2002-11-28 Mitsubishi Pharma Corporation Fused heterocyclic compound and medicinal use thereof
AU2003211931A1 (en) * 2002-02-13 2003-09-04 Takeda Chemical Industries, Ltd. Jnk inhibitor
WO2005030729A1 (en) * 2003-09-23 2005-04-07 Merck & Co., Inc. Isoquinoline potassium channel inhibitors
JP4719151B2 (ja) * 2003-09-23 2011-07-06 メルク・シャープ・エンド・ドーム・コーポレイション イソキノリノンカリウムチャネル阻害剤
EP1667982B1 (en) * 2003-09-23 2013-07-31 Merck Sharp & Dohme Corp. Isoquinolinone potassium channel inhibitors
CA2539541C (en) * 2003-09-23 2010-06-29 Merck & Co., Inc. Isoquinolinone potassium channel inhibitors

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