JP2007502301A5 - - Google Patents
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- Publication number
- JP2007502301A5 JP2007502301A5 JP2006523413A JP2006523413A JP2007502301A5 JP 2007502301 A5 JP2007502301 A5 JP 2007502301A5 JP 2006523413 A JP2006523413 A JP 2006523413A JP 2006523413 A JP2006523413 A JP 2006523413A JP 2007502301 A5 JP2007502301 A5 JP 2007502301A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- platinum complex
- cells
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 29
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 22
- 238000000034 method Methods 0.000 claims 12
- 229910052697 platinum Inorganic materials 0.000 claims 11
- 210000004962 mammalian cell Anatomy 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 241000283690 Bos taurus Species 0.000 claims 2
- 241000282693 Cercopithecidae Species 0.000 claims 2
- 241000282326 Felis catus Species 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 241000282577 Pan troglodytes Species 0.000 claims 2
- 102000004495 STAT3 Transcription Factor Human genes 0.000 claims 2
- 108010017324 STAT3 Transcription Factor Proteins 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 210000005260 human cell Anatomy 0.000 claims 2
- 239000002502 liposome Substances 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 210000004881 tumor cell Anatomy 0.000 claims 2
- 102000007078 STAT Transcription Factors Human genes 0.000 claims 1
- 108010072819 STAT Transcription Factors Proteins 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
- 230000010076 replication Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48122603P | 2003-08-13 | 2003-08-13 | |
| US51558003P | 2003-10-30 | 2003-10-30 | |
| US51994303P | 2003-11-14 | 2003-11-14 | |
| US52529503P | 2003-11-25 | 2003-11-25 | |
| PCT/US2004/026392 WO2005023824A2 (en) | 2003-08-13 | 2004-08-13 | Methods for inhibiting tumor cell proliferation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007502301A JP2007502301A (ja) | 2007-02-08 |
| JP2007502301A5 true JP2007502301A5 (https=) | 2007-09-27 |
Family
ID=34199238
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006523413A Pending JP2007502301A (ja) | 2003-08-13 | 2004-08-13 | 腫瘍細胞の増殖を阻害するための方法 |
| JP2006523414A Pending JP2007502777A (ja) | 2003-08-13 | 2004-08-13 | 腫瘍の処置のための白金錯体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006523414A Pending JP2007502777A (ja) | 2003-08-13 | 2004-08-13 | 腫瘍の処置のための白金錯体 |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US7566798B2 (https=) |
| EP (2) | EP1664070B1 (https=) |
| JP (2) | JP2007502301A (https=) |
| AT (2) | ATE453653T1 (https=) |
| AU (3) | AU2004270655B2 (https=) |
| CA (2) | CA2535584A1 (https=) |
| DE (2) | DE602004015811D1 (https=) |
| WO (2) | WO2005023824A2 (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004270655B2 (en) | 2003-08-13 | 2011-03-24 | University Of South Florida | Methods for inhibiting tumor cell proliferation |
| US20050288365A1 (en) * | 2004-01-06 | 2005-12-29 | Heidi Kay | Platinum complexes and methods for inhibiting tumor cell proliferation |
| WO2005110477A2 (en) * | 2004-04-09 | 2005-11-24 | University Of South Florida | Combination therapies for cancer and proliferative angiopathies |
| JP2008519859A (ja) * | 2004-11-10 | 2008-06-12 | ユニバーシティー オブ サウス フロリダ | 標的化した薬物送達のための白金錯体 |
| WO2006065894A2 (en) * | 2004-12-14 | 2006-06-22 | University Of South Florida | Methods for inhibiting stat3 signaling in immune cells |
| DE102004060934A1 (de) * | 2004-12-17 | 2006-06-29 | Wacker Chemie Ag | Vernetzbare Polyorganosiloxanmassen |
| ATE488507T1 (de) * | 2005-06-30 | 2010-12-15 | Bionumerik Pharmaceuticals Inc | Platinanaloga mit monoazolligand |
| WO2007006019A1 (en) * | 2005-07-06 | 2007-01-11 | University Of South Florida | Materials and methods for screening, diagnosis and prognosis of conditions associated with stat protein expression |
| WO2007013946A2 (en) * | 2005-07-20 | 2007-02-01 | University Of South Florida | Method of predicting responsiveness to chemotherapy and selecting treatments |
| WO2007047623A2 (en) * | 2005-10-14 | 2007-04-26 | University Of South Florida | Methods of inhibiting cell growth and methods of enhancing radiation responses |
| DE102006040647A1 (de) * | 2006-08-30 | 2008-03-13 | Robert Bosch Gmbh | Handwerkzeugmaschine |
| US8026382B2 (en) | 2007-05-18 | 2011-09-27 | Heidi Kay | Lipid raft, caveolin protein, and caveolar function modulation compounds and associated synthetic and therapeutic methods |
| US8895610B1 (en) | 2007-05-18 | 2014-11-25 | Heldi Kay | Platinum (IV) compounds targeting zinc finger domains |
| WO2008155727A1 (en) * | 2007-06-18 | 2008-12-24 | Platco Technologies (Proprietary) Limited | Platinum (iv) complexes |
| HRP20160625T1 (hr) | 2007-09-10 | 2016-08-12 | Boston Biomedical, Inc. | Novi inhibitori stat3 signalnog puta i inhibitori matičnih stanica raka |
| WO2010067335A1 (en) | 2008-12-12 | 2010-06-17 | Platco Technologies (Proprietary) Limited | Platinum (iv) complexes for use in the treatment of proliferative diseases such as cancer |
| EP3012329B1 (en) | 2010-06-18 | 2017-10-25 | Myriad Genetics, Inc. | Methods and materials for assessing loss of heterozygosity |
| WO2012027224A1 (en) | 2010-08-24 | 2012-03-01 | Dana-Farber Cancer Institute, Inc. | Methods for predicting anti-cancer response |
| JP6117194B2 (ja) | 2011-06-17 | 2017-04-19 | ミリアド・ジェネティックス・インコーポレイテッド | アレル不均衡を評価するための方法および材料 |
| RU2491936C2 (ru) * | 2011-07-11 | 2013-09-10 | Борис Николаевич Анисимов | Способ комплексного лечения больных паразитарными заболеваниями |
| BR112014015152A2 (pt) | 2011-12-21 | 2017-07-04 | Myriad Genetics Inc | métodos e materiais para a avaliação da perda de heterozigosidade |
| CA2864481C (en) | 2012-02-23 | 2020-07-14 | Dana-Farber Cancer Institute, Inc. | Methods for predicting anti-cancer response |
| WO2013182645A1 (en) | 2012-06-07 | 2013-12-12 | Institut Curie | Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors |
| US10308986B2 (en) | 2013-03-14 | 2019-06-04 | Children's Medical Center Corporation | Cancer diagnosis, treatment selection and treatment |
| BR112015023568B8 (pt) | 2013-03-15 | 2024-01-02 | Ann Mcfarland Sherri | Composto à base de metal como composto fotodinâmico |
| AU2014248007B2 (en) | 2013-04-05 | 2020-03-26 | Myriad Genetics, Inc. | Methods and materials for assessing homologous recombination deficiency |
| CN104230997B (zh) * | 2013-06-13 | 2017-01-04 | 上海医药工业研究院 | 一种铂（ⅱ）配合物、其制备方法、药物组合物及应用 |
| WO2015013565A1 (en) * | 2013-07-25 | 2015-01-29 | Nemucore Medical Innovations, Inc. | Platinum derivatives for hydrophobic formulations |
| WO2015086473A1 (en) | 2013-12-09 | 2015-06-18 | Institut Curie | Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors |
| CA2958801A1 (en) | 2014-08-15 | 2016-02-18 | Myriad Genetics, Inc. | Methods and materials for assessing homologous recombination deficiency |
| BR112017027277A2 (pt) | 2015-06-19 | 2018-09-04 | Syn Nat Products Entpr Llc | ?método para o tratamento ou prevenção de uma doença e métodos para matar uma célula? |
| BR112017027285A2 (pt) | 2015-06-19 | 2018-09-11 | Syn Nat Products Entpr Llc | ?cocristal, composição farmacêutica e método para o tratamento de uma doença? |
| US10428099B2 (en) | 2015-06-25 | 2019-10-01 | Syn-Nat Products Enterprise LLC | Pharmaceutical co-crystal composition and use thereof |
| WO2018102427A1 (en) | 2016-11-29 | 2018-06-07 | Boston Biomedical, Inc. | Naphthofuran derivatives, preparation, and methods of use thereof |
| MX2020005310A (es) | 2017-11-21 | 2020-10-08 | Medoncare Pharmaceutical Co Ltd | Producto de combinacion que comprende dicicloplatino y metodo de preparacion y uso del mismo. |
| CN112175014B (zh) * | 2020-10-10 | 2021-08-20 | 中国药科大学 | 一种一氧化氮供体型四价铂衍生物、制备方法及其医药用途 |
| EP4141127B1 (en) | 2021-08-30 | 2024-10-09 | Zentrum Familiärer Brust- und Eierstockkrebs Universitätsklinik Köln | Method for assessing homologous recombination deficiency in ovarian cancer cells |
| WO2024063828A1 (en) | 2022-09-21 | 2024-03-28 | Oracle International Corporation | Expert-optimal correlation: contamination factor identification for unsupervised anomaly detection |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4177263A (en) * | 1972-02-28 | 1979-12-04 | Research Corporation | Anti-animal tumor method |
| GB1432563A (en) | 1972-04-10 | 1976-04-22 | Rustenburg Platinum Mines Ltd | Platinum- co-ordination compounds |
| GR851932B (https=) * | 1984-08-14 | 1985-12-13 | Engelhard Corp | |
| JPS6296A (ja) * | 1985-03-06 | 1987-01-06 | Sumitomo Pharmaceut Co Ltd | 脂溶性白金（２）錯体 |
| JPH01156989A (ja) * | 1987-09-25 | 1989-06-20 | Ss Pharmaceut Co Ltd | 新規白金錯体 |
| EP0328274B1 (en) | 1988-02-02 | 1994-10-19 | Johnson Matthey, Inc., | Pt (IV) complexes |
| JP3520367B2 (ja) * | 1994-12-22 | 2004-04-19 | 独立行政法人産業技術総合研究所 | 白金ニトロアンミン系錯体の製造方法 |
| US6008395A (en) * | 1995-02-28 | 1999-12-28 | Kidani; Yoshinori | Platinum (IV) complex, production process thereof and carcinostatic agent containing the same |
| US5922689A (en) * | 1995-09-11 | 1999-07-13 | Unitech Pharmaceuticals, Inc. | Cisplatin analogs for cancer treatment |
| US5849790A (en) | 1995-11-17 | 1998-12-15 | The University Of South Florida | (Mono) ethylenediaminenitroplatinum (IV) complexes with ligands of oxides of nitrogen as possible anti-tumor agents |
| US6145688A (en) * | 1996-07-17 | 2000-11-14 | Smith; James C. | Closure device for containers |
| US5977393A (en) | 1997-11-21 | 1999-11-02 | California Institute Of Technology | Schiff base derivatives of ruthenium and osmium olefin metathesis catalysts |
| KR100246722B1 (ko) * | 1997-12-30 | 2000-04-01 | 박호군 | 경구용 백금 착화합물 항암제 및 그 제조방법 |
| JP2002535247A (ja) * | 1998-11-26 | 2002-10-22 | ペンタファルム アクチェンゲゼルシャフト | 輸送系複合体 |
| EP1146869A2 (en) * | 1999-01-27 | 2001-10-24 | University Of South Florida | Inhibition of stat3 signal transduction for human cancer therapy |
| US6511676B1 (en) * | 1999-11-05 | 2003-01-28 | Teni Boulikas | Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes |
| US7034109B2 (en) * | 2000-10-13 | 2006-04-25 | Christophe Bonny | Intracellular delivery of biological effectors |
| US7033597B2 (en) * | 2000-10-13 | 2006-04-25 | Université de Lausanne | Intracellular delivery of biological effectors |
| US7638122B2 (en) * | 2003-03-07 | 2009-12-29 | University Of South Florida | Stat3 antagonists and their use as vaccines against cancer |
| WO2005002508A2 (en) | 2003-06-11 | 2005-01-13 | Access Pharmaceuticals, Inc. | Macromolecular platinum chelates |
| AU2004270655B2 (en) | 2003-08-13 | 2011-03-24 | University Of South Florida | Methods for inhibiting tumor cell proliferation |
| US20050288365A1 (en) | 2004-01-06 | 2005-12-29 | Heidi Kay | Platinum complexes and methods for inhibiting tumor cell proliferation |
| JP2008519859A (ja) | 2004-11-10 | 2008-06-12 | ユニバーシティー オブ サウス フロリダ | 標的化した薬物送達のための白金錯体 |
| WO2007006019A1 (en) | 2005-07-06 | 2007-01-11 | University Of South Florida | Materials and methods for screening, diagnosis and prognosis of conditions associated with stat protein expression |
-
2004
- 2004-08-13 AU AU2004270655A patent/AU2004270655B2/en not_active Ceased
- 2004-08-13 CA CA002535584A patent/CA2535584A1/en not_active Abandoned
- 2004-08-13 JP JP2006523413A patent/JP2007502301A/ja active Pending
- 2004-08-13 JP JP2006523414A patent/JP2007502777A/ja active Pending
- 2004-08-13 EP EP04809566A patent/EP1664070B1/en not_active Expired - Lifetime
- 2004-08-13 US US10/918,769 patent/US7566798B2/en not_active Expired - Fee Related
- 2004-08-13 DE DE602004015811T patent/DE602004015811D1/de not_active Expired - Lifetime
- 2004-08-13 AU AU2004264421A patent/AU2004264421B2/en not_active Ceased
- 2004-08-13 DE DE602004024909T patent/DE602004024909D1/de not_active Expired - Lifetime
- 2004-08-13 WO PCT/US2004/026392 patent/WO2005023824A2/en not_active Ceased
- 2004-08-13 WO PCT/US2004/026393 patent/WO2005016946A2/en not_active Ceased
- 2004-08-13 CA CA002535762A patent/CA2535762A1/en not_active Abandoned
- 2004-08-13 US US10/918,762 patent/US7238372B2/en not_active Expired - Lifetime
- 2004-08-13 AT AT04781131T patent/ATE453653T1/de not_active IP Right Cessation
- 2004-08-13 EP EP04781131A patent/EP1675864B1/en not_active Expired - Lifetime
- 2004-08-13 AT AT04809566T patent/ATE404574T1/de not_active IP Right Cessation
-
2007
- 2007-01-31 US US11/701,907 patent/US7763585B2/en not_active Expired - Fee Related
-
2009
- 2009-07-21 US US12/506,913 patent/US7759510B2/en not_active Expired - Fee Related
-
2010
- 2010-07-13 US US12/835,114 patent/US8247445B2/en not_active Expired - Fee Related
- 2010-07-15 US US12/837,046 patent/US8598230B2/en not_active Expired - Fee Related
-
2011
- 2011-05-23 AU AU2011202386A patent/AU2011202386A1/en not_active Abandoned
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