JP2007263655A - コンゴレッドによる皮膚の鑑別方法 - Google Patents
コンゴレッドによる皮膚の鑑別方法 Download PDFInfo
- Publication number
- JP2007263655A JP2007263655A JP2006087376A JP2006087376A JP2007263655A JP 2007263655 A JP2007263655 A JP 2007263655A JP 2006087376 A JP2006087376 A JP 2006087376A JP 2006087376 A JP2006087376 A JP 2006087376A JP 2007263655 A JP2007263655 A JP 2007263655A
- Authority
- JP
- Japan
- Prior art keywords
- skin
- stratum corneum
- horny layer
- keratin
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract description 28
- IQFVPQOLBLOTPF-HKXUKFGYSA-L congo red Chemical compound [Na+].[Na+].C1=CC=CC2=C(N)C(/N=N/C3=CC=C(C=C3)C3=CC=C(C=C3)/N=N/C3=C(C4=CC=CC=C4C(=C3)S([O-])(=O)=O)N)=CC(S([O-])(=O)=O)=C21 IQFVPQOLBLOTPF-HKXUKFGYSA-L 0.000 title claims abstract description 17
- 102000011782 Keratins Human genes 0.000 claims abstract description 39
- 108010076876 Keratins Proteins 0.000 claims abstract description 39
- 210000003491 skin Anatomy 0.000 claims description 96
- 210000000434 stratum corneum Anatomy 0.000 claims description 53
- 239000002537 cosmetic Substances 0.000 claims description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 11
- 239000002390 adhesive tape Substances 0.000 claims description 11
- 238000012850 discrimination method Methods 0.000 claims description 11
- 238000010186 staining Methods 0.000 claims description 8
- 239000012188 paraffin wax Substances 0.000 claims description 7
- 230000004069 differentiation Effects 0.000 claims description 6
- 239000000975 dye Substances 0.000 claims description 5
- 239000012192 staining solution Substances 0.000 claims description 5
- 235000007173 Abies balsamea Nutrition 0.000 claims description 4
- 239000004857 Balsam Substances 0.000 claims description 4
- 244000018716 Impatiens biflora Species 0.000 claims description 4
- 239000000853 adhesive Substances 0.000 claims description 4
- 230000001070 adhesive effect Effects 0.000 claims description 4
- 238000005119 centrifugation Methods 0.000 claims description 4
- 239000008188 pellet Substances 0.000 claims description 4
- 239000003960 organic solvent Substances 0.000 claims description 3
- 239000001044 red dye Substances 0.000 claims description 3
- 230000000052 comparative effect Effects 0.000 claims description 2
- 238000007447 staining method Methods 0.000 claims description 2
- SUXCALIDMIIJCK-UHFFFAOYSA-L disodium;4-amino-3-[[4-[4-[(1-amino-4-sulfonatonaphthalen-2-yl)diazenyl]-3-methylphenyl]-2-methylphenyl]diazenyl]naphthalene-1-sulfonate Chemical compound [Na+].[Na+].C1=CC=CC2=C(N)C(N=NC3=CC=C(C=C3C)C=3C=C(C(=CC=3)N=NC=3C(=C4C=CC=CC4=C(C=3)S([O-])(=O)=O)N)C)=CC(S([O-])(=O)=O)=C21 SUXCALIDMIIJCK-UHFFFAOYSA-L 0.000 abstract 1
- 230000010287 polarization Effects 0.000 description 28
- 239000010410 layer Substances 0.000 description 27
- 238000010438 heat treatment Methods 0.000 description 10
- 239000006210 lotion Substances 0.000 description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 102000004169 proteins and genes Human genes 0.000 description 6
- 108090000623 proteins and genes Proteins 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 229920000289 Polyquaternium Polymers 0.000 description 3
- 239000004359 castor oil Substances 0.000 description 3
- 235000019438 castor oil Nutrition 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 3
- 239000001257 hydrogen Substances 0.000 description 3
- 229910052739 hydrogen Inorganic materials 0.000 description 3
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 description 3
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 238000010219 correlation analysis Methods 0.000 description 2
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- 239000001054 red pigment Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000002344 surface layer Substances 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 102000009091 Amyloidogenic Proteins Human genes 0.000 description 1
- 108010048112 Amyloidogenic Proteins Proteins 0.000 description 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Natural products OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 1
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 description 1
- 229940122858 Elastase inhibitor Drugs 0.000 description 1
- 239000005770 Eugenol Substances 0.000 description 1
- 229940122393 Hyaluronidase inhibitor Drugs 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 description 1
- 208000034189 Sclerosis Diseases 0.000 description 1
- 229920002385 Sodium hyaluronate Polymers 0.000 description 1
- 201000009594 Systemic Scleroderma Diseases 0.000 description 1
- 206010042953 Systemic sclerosis Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 238000007605 air drying Methods 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- -1 ascorbic acid glucoside Chemical class 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000009223 counseling Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000004043 dyeing Methods 0.000 description 1
- 239000003602 elastase inhibitor Substances 0.000 description 1
- 229960002217 eugenol Drugs 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000002795 fluorescence method Methods 0.000 description 1
- 238000002073 fluorescence micrograph Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 229910001507 metal halide Inorganic materials 0.000 description 1
- 150000005309 metal halides Chemical class 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000010187 selection method Methods 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 229940010747 sodium hyaluronate Drugs 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 230000005945 translocation Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Images
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006087376A JP2007263655A (ja) | 2006-03-28 | 2006-03-28 | コンゴレッドによる皮膚の鑑別方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006087376A JP2007263655A (ja) | 2006-03-28 | 2006-03-28 | コンゴレッドによる皮膚の鑑別方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007263655A true JP2007263655A (ja) | 2007-10-11 |
| JP2007263655A5 JP2007263655A5 (https=) | 2009-04-09 |
Family
ID=38636798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006087376A Pending JP2007263655A (ja) | 2006-03-28 | 2006-03-28 | コンゴレッドによる皮膚の鑑別方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2007263655A (https=) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101278566B1 (ko) | 2011-10-28 | 2013-06-25 | 최미정 | 편광현미경을 이용한 천연모 모수질 형태분석시스템 및 방법 |
| WO2014112643A1 (ja) | 2013-01-21 | 2014-07-24 | 株式会社資生堂 | 角層状態の評価方法、及び化粧料の角層改善効果についての評価方法 |
| JP2018108373A (ja) * | 2016-12-28 | 2018-07-12 | ポーラ化成工業株式会社 | 肌状態認識システム |
| JP2024019957A (ja) * | 2022-08-01 | 2024-02-14 | 株式会社ファンケル | 皮膚粘弾性指標推定方法 |
| JP7626353B2 (ja) | 2019-09-30 | 2025-02-04 | 小林製薬株式会社 | 皮膚の状態の推定装置 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11344489A (ja) * | 1998-06-02 | 1999-12-14 | Shiseido Co Ltd | 角層のメラニンの定量方法 |
| JP2003516929A (ja) * | 2000-06-01 | 2003-05-20 | ニユーララブ・リミテツド | アミロイド形成性疾患の予防および治療 |
| JP2005348991A (ja) * | 2004-06-11 | 2005-12-22 | Pola Chem Ind Inc | 肌の鑑別方法、それによる化粧料の選択法及びそれらを利用した化粧料の提示方法 |
-
2006
- 2006-03-28 JP JP2006087376A patent/JP2007263655A/ja active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11344489A (ja) * | 1998-06-02 | 1999-12-14 | Shiseido Co Ltd | 角層のメラニンの定量方法 |
| JP2003516929A (ja) * | 2000-06-01 | 2003-05-20 | ニユーララブ・リミテツド | アミロイド形成性疾患の予防および治療 |
| JP2005348991A (ja) * | 2004-06-11 | 2005-12-22 | Pola Chem Ind Inc | 肌の鑑別方法、それによる化粧料の選択法及びそれらを利用した化粧料の提示方法 |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101278566B1 (ko) | 2011-10-28 | 2013-06-25 | 최미정 | 편광현미경을 이용한 천연모 모수질 형태분석시스템 및 방법 |
| WO2014112643A1 (ja) | 2013-01-21 | 2014-07-24 | 株式会社資生堂 | 角層状態の評価方法、及び化粧料の角層改善効果についての評価方法 |
| KR20150110485A (ko) | 2013-01-21 | 2015-10-02 | 가부시키가이샤 시세이도 | 각질층 상태의 평가 방법 및 화장료의 각질층 개선 효과에 관한 평가 방법 |
| US9970848B2 (en) | 2013-01-21 | 2018-05-15 | Shiseido Company, Ltd. | Method for evaluating state of horny layer and method for evaluating horny layer improvement effect of cosmetic preparation |
| KR102105222B1 (ko) | 2013-01-21 | 2020-04-27 | 가부시키가이샤 시세이도 | 각질층 상태의 평가 방법 및 화장료의 각질층 개선 효과에 관한 평가 방법 |
| JP2018108373A (ja) * | 2016-12-28 | 2018-07-12 | ポーラ化成工業株式会社 | 肌状態認識システム |
| JP7001469B2 (ja) | 2016-12-28 | 2022-01-19 | ポーラ化成工業株式会社 | 肌状態認識システム |
| JP7626353B2 (ja) | 2019-09-30 | 2025-02-04 | 小林製薬株式会社 | 皮膚の状態の推定装置 |
| JP2024019957A (ja) * | 2022-08-01 | 2024-02-14 | 株式会社ファンケル | 皮膚粘弾性指標推定方法 |
| JP7806355B2 (ja) | 2022-08-01 | 2026-01-27 | 株式会社ファンケル | 皮膚粘弾性指標推定方法 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Choe et al. | Age related depth profiles of human Stratum Corneum barrier-related molecular parameters by confocal Raman microscopy in vivo | |
| US7632633B2 (en) | Method for determining the degree of protein oxidation in a skin sample using oxidized protein in stratum corneum as an indicator | |
| Czekalla et al. | Impact of body site, age, and gender on the collagen/elastin index by noninvasive in vivo vertical two-photon microscopy | |
| Caetano et al. | In vivo confocal Raman spectroscopy for intrinsic aging and photoaging assessment | |
| Rigal et al. | Raman confocal microscopy and biophysics multiparametric characterization of the skin barrier evolution with age | |
| JP2012161371A (ja) | 皮膚表層の粘弾性を調べることによる肌理評価法 | |
| JP5065237B2 (ja) | アトピー性皮膚炎の局所病態の非侵襲的評価方法 | |
| CN105699654A (zh) | 皮肤角质层的ngal的表达量的用途 | |
| JP2007263655A (ja) | コンゴレッドによる皮膚の鑑別方法 | |
| JP6419654B2 (ja) | 発毛の状態及び頭皮の圧縮応力の評価方法 | |
| JP4549108B2 (ja) | 肌の柔軟性の測定方法 | |
| JP5665583B2 (ja) | 肌状態評価方法 | |
| JPWO2020195829A1 (ja) | 皮膚の状態を評価する方法 | |
| JP4469762B2 (ja) | 敏感肌の評価方法及びその評価キット | |
| JP5096988B2 (ja) | 皮膚角層の重層剥離状態測定方法 | |
| JP3667511B2 (ja) | ストレスの鑑別法 | |
| WO2020195829A1 (ja) | 皮膚の状態を評価する方法 | |
| CN114052666A (zh) | 评估脸部皮肤年龄的方法及在化妆品功效测试中的应用 | |
| Louis et al. | Evaluation of Glycogen Content in Oral Exfoliated Cells of Diabetes Mellitus Patients based on Staining Intensity with Periodic Acid Schiff. | |
| JP7853060B2 (ja) | 肌状態特徴量推定方法 | |
| Nadiasari et al. | The sensitivity and specificity of Chicago Sky Blue (CSB) dye in comparisson with Potassium Hydroxide (KOH) method for superficial dermatomycosis | |
| Arabiun et al. | Comparison of the concentration and types of the proteins present in maxillofacial odontogenic cysts fluid | |
| JP7485462B2 (ja) | デスモグレイン量の推定装置及び推定プログラム並びに肌のシミ濃度推定装置及び推定プログラム | |
| JP5100481B2 (ja) | 皮膚角層水分量、コレステロール量測定方法 | |
| EP2984488A1 (en) | Cervical sample preparation for reduced variability in raman spectroscopy |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20090219 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20090219 |
|
| RD03 | Notification of appointment of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7423 Effective date: 20090219 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20101214 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20101216 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20110412 |