JP2006524342A5 - - Google Patents
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- Publication number
- JP2006524342A5 JP2006524342A5 JP2006513114A JP2006513114A JP2006524342A5 JP 2006524342 A5 JP2006524342 A5 JP 2006524342A5 JP 2006513114 A JP2006513114 A JP 2006513114A JP 2006513114 A JP2006513114 A JP 2006513114A JP 2006524342 A5 JP2006524342 A5 JP 2006524342A5
- Authority
- JP
- Japan
- Prior art keywords
- individual
- complement
- bound
- platelets obtained
- lupus erythematosus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108010042293 complement C4d Proteins 0.000 claims 43
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 31
- 238000000034 method Methods 0.000 claims 26
- 101001070790 Homo sapiens Platelet glycoprotein Ib alpha chain Proteins 0.000 claims 10
- 102100034173 Platelet glycoprotein Ib alpha chain Human genes 0.000 claims 10
- 238000002372 labelling Methods 0.000 claims 7
- 238000000684 flow cytometry Methods 0.000 claims 6
- 230000009266 disease activity Effects 0.000 claims 3
- 238000012544 monitoring process Methods 0.000 claims 3
- 230000000295 complement effect Effects 0.000 claims 2
- 238000011002 quantification Methods 0.000 claims 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46344703P | 2003-04-16 | 2003-04-16 | |
| PCT/US2004/011982 WO2004093647A2 (en) | 2003-04-16 | 2004-04-16 | Identification and monitoring of systematic lupus erythematosus |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006524342A JP2006524342A (ja) | 2006-10-26 |
| JP2006524342A5 true JP2006524342A5 (cg-RX-API-DMAC7.html) | 2007-06-07 |
| JP4550051B2 JP4550051B2 (ja) | 2010-09-22 |
Family
ID=33310779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006513114A Expired - Lifetime JP4550051B2 (ja) | 2003-04-16 | 2004-04-16 | 全身性エリテマトーデスの同定およびモニタリング |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7588905B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1618379B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4550051B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE552501T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2004232007B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2522261A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2004093647A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20060015646A (ko) | 2003-06-13 | 2006-02-17 | 유니버시티 오브 피츠버그 | 면역, 혈액 및 염증성 질환의 모니터링 방법 |
| US20080131914A1 (en) * | 2005-09-14 | 2008-06-05 | Ahearn Joseph M | Assessing risk of cerebrovascular thrombosis by measuring c4d |
| US8062852B2 (en) | 2007-10-01 | 2011-11-22 | The Children's Hospital And Regional Medical Center | Detection and treatment of autoimmune disorders |
| WO2010045611A2 (en) * | 2008-10-16 | 2010-04-22 | Cypress Bioscience, Inc. | Method for diagnosis and monitoring of disease activity and response to treatment in systemic lupus erythematosus (sle) and other autoimmune diseases |
| JP5625155B2 (ja) * | 2010-07-30 | 2014-11-19 | 国立大学法人 東京大学 | ホスファチジルセリン特異的ホスホリパーゼａ１測定による全身性エリテマトーデスの検査方法および検査薬 |
| EP2673644B1 (en) | 2011-02-11 | 2016-02-10 | Exagen Diagnostics, Inc. | Methods for diagnosing systemic lupus erythematosus |
| US9863946B2 (en) | 2013-02-08 | 2018-01-09 | Allegheny-Singer Research Institute | Cell-bound complement activation products as diagnostic biomarkers for pre-lupus |
| EP2954071B1 (en) | 2013-02-08 | 2020-08-12 | Allegheny-Singer Research Institute | Cell-bound complement activation products as diagnostic biomarkers for pre-lupus |
| US11531033B2 (en) | 2013-03-15 | 2022-12-20 | Exagen Inc. | Methods for treating and diagnosing systemic lupus erythematosus |
| US10105413B2 (en) | 2013-06-13 | 2018-10-23 | Medical Research & Development Fund for Health Services Bnai Zion Medical Center | Semaphorin 3A for treatment of systemic lupus erythematosus |
| JP6674543B2 (ja) | 2015-07-31 | 2020-04-01 | アレゲーニー・シンガー リサーチ インスティチュート | 抗体に基づく薬物のコンパニオン診断としての細胞結合補体活性化産物アッセイ |
| WO2017205532A1 (en) | 2016-05-24 | 2017-11-30 | Allegheny-Singer Research Institute | Methods and systems using c4 gene copy number and cell-bound complement activation products for identification of lupus and pre-lupus |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU686577B2 (en) | 1992-10-30 | 1998-02-12 | Innogenetics, Inc. | Measurement of total molecule in a sample and methods based thereon |
| EP1066368A4 (en) * | 1998-03-02 | 2002-08-21 | Compucyte Corp | SELECTIVE CELL ANALYSIS |
| JP4570872B2 (ja) * | 2001-09-10 | 2010-10-27 | ユニヴァーシティ オブ ピッツバーグ | 全身性紅斑性狼瘡および強皮症の診断およびモニタリング方法 |
| KR20060015646A (ko) * | 2003-06-13 | 2006-02-17 | 유니버시티 오브 피츠버그 | 면역, 혈액 및 염증성 질환의 모니터링 방법 |
| EP1756571B8 (en) * | 2004-04-09 | 2010-10-13 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Real time method of detecting acute inflammatory conditions |
| ES2353311T3 (es) * | 2004-05-11 | 2011-03-01 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Diagnóstico de enfermedades o afecciones inflamatorias para la medición de componentes del complemento sobre la superficie de glóbulos blancos. |
| US7679298B2 (en) * | 2006-08-17 | 2010-03-16 | General Electric Company | Locomotive wheel speed control |
-
2004
- 2004-04-16 CA CA002522261A patent/CA2522261A1/en not_active Abandoned
- 2004-04-16 WO PCT/US2004/011982 patent/WO2004093647A2/en not_active Ceased
- 2004-04-16 JP JP2006513114A patent/JP4550051B2/ja not_active Expired - Lifetime
- 2004-04-16 AU AU2004232007A patent/AU2004232007B2/en not_active Ceased
- 2004-04-16 AT AT04759986T patent/ATE552501T1/de active
- 2004-04-16 US US10/552,177 patent/US7588905B2/en not_active Expired - Lifetime
- 2004-04-16 EP EP04759986A patent/EP1618379B1/en not_active Expired - Lifetime
-
2009
- 2009-08-07 US US12/538,001 patent/US8126654B2/en not_active Expired - Lifetime
-
2012
- 2012-01-25 US US13/358,428 patent/US20120122241A1/en not_active Abandoned
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