AU2004232007B2 - Identification and monitoring of systematic lupus erythematosus - Google Patents

Identification and monitoring of systematic lupus erythematosus Download PDF

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Publication number
AU2004232007B2
AU2004232007B2 AU2004232007A AU2004232007A AU2004232007B2 AU 2004232007 B2 AU2004232007 B2 AU 2004232007B2 AU 2004232007 A AU2004232007 A AU 2004232007A AU 2004232007 A AU2004232007 A AU 2004232007A AU 2004232007 B2 AU2004232007 B2 AU 2004232007B2
Authority
AU
Australia
Prior art keywords
individual
complement
lupus erythematosus
systemic lupus
platelets obtained
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2004232007A
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English (en)
Other versions
AU2004232007A1 (en
Inventor
Joseph M. Ahearn
Susan M. Manzi
Jeannine Navratil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pittsburgh
Original Assignee
University of Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pittsburgh filed Critical University of Pittsburgh
Publication of AU2004232007A1 publication Critical patent/AU2004232007A1/en
Application granted granted Critical
Publication of AU2004232007B2 publication Critical patent/AU2004232007B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/104—Lupus erythematosus [SLE]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/973—Simultaneous determination of more than one analyte
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/821—Chemistry: analytical and immunological testing involving complement factors or complement systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Small-Scale Networks (AREA)
  • Testing Of Coins (AREA)
  • Dc Digital Transmission (AREA)
AU2004232007A 2003-04-16 2004-04-16 Identification and monitoring of systematic lupus erythematosus Ceased AU2004232007B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46344703P 2003-04-16 2003-04-16
US60/463,447 2003-04-16
PCT/US2004/011982 WO2004093647A2 (en) 2003-04-16 2004-04-16 Identification and monitoring of systematic lupus erythematosus

Publications (2)

Publication Number Publication Date
AU2004232007A1 AU2004232007A1 (en) 2004-11-04
AU2004232007B2 true AU2004232007B2 (en) 2009-10-22

Family

ID=33310779

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004232007A Ceased AU2004232007B2 (en) 2003-04-16 2004-04-16 Identification and monitoring of systematic lupus erythematosus

Country Status (7)

Country Link
US (3) US7588905B2 (cg-RX-API-DMAC7.html)
EP (1) EP1618379B1 (cg-RX-API-DMAC7.html)
JP (1) JP4550051B2 (cg-RX-API-DMAC7.html)
AT (1) ATE552501T1 (cg-RX-API-DMAC7.html)
AU (1) AU2004232007B2 (cg-RX-API-DMAC7.html)
CA (1) CA2522261A1 (cg-RX-API-DMAC7.html)
WO (1) WO2004093647A2 (cg-RX-API-DMAC7.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060015646A (ko) 2003-06-13 2006-02-17 유니버시티 오브 피츠버그 면역, 혈액 및 염증성 질환의 모니터링 방법
US20080131914A1 (en) * 2005-09-14 2008-06-05 Ahearn Joseph M Assessing risk of cerebrovascular thrombosis by measuring c4d
US8062852B2 (en) 2007-10-01 2011-11-22 The Children's Hospital And Regional Medical Center Detection and treatment of autoimmune disorders
WO2010045611A2 (en) * 2008-10-16 2010-04-22 Cypress Bioscience, Inc. Method for diagnosis and monitoring of disease activity and response to treatment in systemic lupus erythematosus (sle) and other autoimmune diseases
JP5625155B2 (ja) * 2010-07-30 2014-11-19 国立大学法人 東京大学 ホスファチジルセリン特異的ホスホリパーゼａ１測定による全身性エリテマトーデスの検査方法および検査薬
EP2673644B1 (en) 2011-02-11 2016-02-10 Exagen Diagnostics, Inc. Methods for diagnosing systemic lupus erythematosus
US9863946B2 (en) 2013-02-08 2018-01-09 Allegheny-Singer Research Institute Cell-bound complement activation products as diagnostic biomarkers for pre-lupus
EP2954071B1 (en) 2013-02-08 2020-08-12 Allegheny-Singer Research Institute Cell-bound complement activation products as diagnostic biomarkers for pre-lupus
US11531033B2 (en) 2013-03-15 2022-12-20 Exagen Inc. Methods for treating and diagnosing systemic lupus erythematosus
US10105413B2 (en) 2013-06-13 2018-10-23 Medical Research & Development Fund for Health Services Bnai Zion Medical Center Semaphorin 3A for treatment of systemic lupus erythematosus
JP6674543B2 (ja) 2015-07-31 2020-04-01 アレゲーニー・シンガー リサーチ インスティチュート 抗体に基づく薬物のコンパニオン診断としての細胞結合補体活性化産物アッセイ
WO2017205532A1 (en) 2016-05-24 2017-11-30 Allegheny-Singer Research Institute Methods and systems using c4 gene copy number and cell-bound complement activation products for identification of lupus and pre-lupus

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003022223A2 (en) * 2001-09-10 2003-03-20 University Of Pittsburgh Diagnosis and monitoring of systemic lupus erythematosus and of scleroderma

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU686577B2 (en) 1992-10-30 1998-02-12 Innogenetics, Inc. Measurement of total molecule in a sample and methods based thereon
EP1066368A4 (en) * 1998-03-02 2002-08-21 Compucyte Corp SELECTIVE CELL ANALYSIS
KR20060015646A (ko) * 2003-06-13 2006-02-17 유니버시티 오브 피츠버그 면역, 혈액 및 염증성 질환의 모니터링 방법
EP1756571B8 (en) * 2004-04-09 2010-10-13 University of Pittsburgh - Of the Commonwealth System of Higher Education Real time method of detecting acute inflammatory conditions
ES2353311T3 (es) * 2004-05-11 2011-03-01 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Diagnóstico de enfermedades o afecciones inflamatorias para la medición de componentes del complemento sobre la superficie de glóbulos blancos.
US7679298B2 (en) * 2006-08-17 2010-03-16 General Electric Company Locomotive wheel speed control

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003022223A2 (en) * 2001-09-10 2003-03-20 University Of Pittsburgh Diagnosis and monitoring of systemic lupus erythematosus and of scleroderma

Also Published As

Publication number Publication date
EP1618379A2 (en) 2006-01-25
JP4550051B2 (ja) 2010-09-22
WO2004093647A3 (en) 2005-03-10
ATE552501T1 (de) 2012-04-15
CA2522261A1 (en) 2004-11-04
JP2006524342A (ja) 2006-10-26
US7588905B2 (en) 2009-09-15
WO2004093647A2 (en) 2004-11-04
US20070178536A1 (en) 2007-08-02
EP1618379A4 (en) 2008-05-07
US8126654B2 (en) 2012-02-28
AU2004232007A1 (en) 2004-11-04
EP1618379B1 (en) 2012-04-04
US20090299948A1 (en) 2009-12-03
US20120122241A1 (en) 2012-05-17

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired