JP2006524242A5 - - Google Patents

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Publication number
JP2006524242A5
JP2006524242A5 JP2006509429A JP2006509429A JP2006524242A5 JP 2006524242 A5 JP2006524242 A5 JP 2006524242A5 JP 2006509429 A JP2006509429 A JP 2006509429A JP 2006509429 A JP2006509429 A JP 2006509429A JP 2006524242 A5 JP2006524242 A5 JP 2006524242A5
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JP
Japan
Prior art keywords
cxcr4
peptide antagonist
sirna
antagonist
cancer cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006509429A
Other languages
English (en)
Japanese (ja)
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JP2006524242A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/009570 external-priority patent/WO2004087068A2/en
Publication of JP2006524242A publication Critical patent/JP2006524242A/ja
Publication of JP2006524242A5 publication Critical patent/JP2006524242A5/ja
Pending legal-status Critical Current

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JP2006509429A 2003-03-27 2004-03-26 Cxcr4アンタゴニストおよびそれらの使用方法 Pending JP2006524242A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45821703P 2003-03-27 2003-03-27
PCT/US2004/009570 WO2004087068A2 (en) 2003-03-27 2004-03-26 Cxcr4 antagonists and methods of their use

Publications (2)

Publication Number Publication Date
JP2006524242A JP2006524242A (ja) 2006-10-26
JP2006524242A5 true JP2006524242A5 (https=) 2007-05-31

Family

ID=33131767

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006509429A Pending JP2006524242A (ja) 2003-03-27 2004-03-26 Cxcr4アンタゴニストおよびそれらの使用方法

Country Status (5)

Country Link
US (1) US20070258893A1 (https=)
EP (1) EP1608318A4 (https=)
JP (1) JP2006524242A (https=)
CA (1) CA2520406A1 (https=)
WO (1) WO2004087068A2 (https=)

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CA2445826C (en) 2001-05-02 2014-03-25 Purdue Research Foundation Treatment and diagnosis of macrophage mediated disease
US8043602B2 (en) 2002-02-07 2011-10-25 Endocyte, Inc. Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology
US8043603B2 (en) 2002-02-07 2011-10-25 Endocyte, Inc. Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology
WO2004020462A1 (ja) 2002-08-27 2004-03-11 Fujii, Nobutaka Cxcr4拮抗薬およびその用途
WO2005103721A1 (en) * 2004-04-20 2005-11-03 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with cxc chemokine receptor 4 (cxcr4)
AU2006203826A1 (en) 2005-01-07 2006-07-13 Emory University CXCR4 antagonists for the treatment of HIV infection
WO2006091112A1 (en) * 2005-02-22 2006-08-31 Genesis Reasearch And Development Corporation Limited Compositions for the delivery of rna interference molecules and methods for their use
US8569280B2 (en) 2005-04-25 2013-10-29 Immune Disease Institute Methods for the treatment of multiple myeloma
US7825088B2 (en) * 2005-04-25 2010-11-02 The Cbr Institute For Biomedical Research, Inc. Methods for the treatment of multiple myeloma
DE102005023170A1 (de) * 2005-05-19 2006-11-23 Curevac Gmbh Optimierte Formulierung für mRNA
US9034814B2 (en) 2005-05-25 2015-05-19 Hadasit Medical Research Services And Development Ltd. CXCR4 antagonists for wound healing and re-epithelialization
US20070009434A1 (en) 2005-07-05 2007-01-11 Low Philip S Imaging and therapeutic method using monocytes
CA2619828A1 (en) * 2005-08-19 2007-02-22 Genzyme Corporation Methods to enhance chemotherapy
US8795633B2 (en) 2005-09-23 2014-08-05 Purdue Research Foundation Multiphoton in vivo flow cytometry method and device
WO2007058322A1 (ja) 2005-11-18 2007-05-24 Ono Pharmaceutical Co., Ltd. 塩基性基を含有する化合物およびその用途
EP2397148A3 (en) * 2006-02-02 2012-04-25 Allergan, Inc. Compositions and methods for the treatment of ophthalmic disease
WO2007096662A2 (en) * 2006-02-27 2007-08-30 Technische Universität München Cancer imaging and treatment
TW200808328A (en) * 2006-06-02 2008-02-16 Alcon Mfg Ltd RNAi-mediated inhibition of stromal cell-derived factor 1-related targets for treatment of neovascularization-related conditions
EP2041067A4 (en) 2006-07-11 2009-11-25 Univ Emory CXER4 ANTAGONISTS WITH DIAZINE AND TRIAZINE STRUCTURES FOR THE TREATMENT OF MEDICAL PROBLEMS
JP2010509570A (ja) 2006-11-03 2010-03-25 パーデュー・リサーチ・ファウンデーション エクスビボフローサイトメトリーの方法および装置
CA2673719C (en) 2006-12-21 2018-07-24 Biokine Therapeutics Ltd. T-140 peptide analogs having cxcr4 super-agonist activity for bone marrow recovery
US8586595B2 (en) 2007-02-07 2013-11-19 Purdue Research Foundation Positron emission tomography imaging method
CA2688308A1 (en) 2007-05-25 2008-12-04 Purdue Research Foundation Method of imaging localized infections
EP2197469A2 (en) * 2007-09-11 2010-06-23 Mondobiotech Laboratories AG Use of nf-kappab inhibitor sn50 and optionally angiotensin iii as therapeutic agents in the treatment of eg hbv infection
AU2009228034A1 (en) 2008-03-28 2009-10-01 Altiris Therapeutics Chemokine receptor modulators
AU2009311645C1 (en) 2008-11-04 2014-10-02 Acer Therapeutics Inc. CXCR4 receptor compounds
US9427456B2 (en) 2009-06-14 2016-08-30 Biokine Therapeutics Ltd. Peptide therapy for increasing platelet levels
WO2011094389A2 (en) * 2010-01-27 2011-08-04 Emory University Cxcr4 antagonists for imaging of cancer and inflammatory disorders
US9155795B2 (en) 2010-02-26 2015-10-13 Anchor Therapeutics, Inc. CXCR4 receptor compounds
US20130310442A1 (en) * 2010-09-09 2013-11-21 Noxxon Pharma Ag SDF-1 Binding Nucleic Acids and the use Thereof in Cancer Treatment
EP2663320A1 (en) 2011-01-10 2013-11-20 Biokine Therapeutics Ltd. Peptides and compositions for the treatment of neuroectodermal derived tumors and retinoblastoma
EP2476441A1 (en) 2011-01-13 2012-07-18 Universitat Autònoma De Barcelona Methods and reagents for efficient and targeted delivery of therapeutic molecules to CXCR4 cells
CA2852160A1 (en) 2011-10-28 2013-05-02 Galderma Research & Development New leukocyte infiltrate markers for rosacea and uses thereof
US9439942B2 (en) 2012-04-24 2016-09-13 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
EP2978439B1 (en) 2013-03-24 2017-08-16 Biokine Therapeutics Ltd. A combination of a cxcr4 antagonist and cytarabine for use in treating myeloid leukemia
CA2928315C (en) 2013-10-31 2023-03-21 Biokine Therapeutics Ltd. Methods of treating acute myeloid leukemia with a flt3 mutation
CA2937992A1 (en) 2014-02-03 2015-08-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of eliminating stem cells
KR101700946B1 (ko) * 2014-11-11 2017-02-02 연세대학교 산학협력단 Cxcr4 길항제를 포함하는 피부 색소침착의 예방 또는 개선용 조성물
US11311552B2 (en) * 2015-04-02 2022-04-26 Proximagen, Llc Therapies for cancer
IL274572B2 (en) 2015-07-16 2024-01-01 Biolinerx Ltd Compositions and methods for treating cancer
WO2017011517A1 (en) 2015-07-16 2017-01-19 Emory University Bis-amines, compositions, and uses related to cxcr4 inhibition
US10434195B2 (en) 2015-08-03 2019-10-08 Emory University Methylsulfonamide derivatives and uses related thereto
CN109310733A (zh) 2016-02-23 2019-02-05 百欧林纳克斯有限公司 治疗急性骨髓性白血病的方法
EP3856225A1 (en) 2018-09-25 2021-08-04 BioLineRx Ltd. Methods of selecting treatment for cxcr4-associated cancer
CN110590744B (zh) * 2019-07-03 2021-11-02 河南省人民医院 一种靶向趋化因子受体cxcr4的小分子类pet显像剂

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WO2000009152A1 (en) * 1998-08-14 2000-02-24 The University Of British Columbia Therapeutic chemokine receptor antagonists
WO2004020462A1 (ja) * 2002-08-27 2004-03-11 Fujii, Nobutaka Cxcr4拮抗薬およびその用途

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