JP2006522102A - 光診断法および光線力学的療法の両方のためのターゲット剤 - Google Patents

光診断法および光線力学的療法の両方のためのターゲット剤 Download PDF

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JP2006522102A
JP2006522102A JP2006507106A JP2006507106A JP2006522102A JP 2006522102 A JP2006522102 A JP 2006522102A JP 2006507106 A JP2006507106 A JP 2006507106A JP 2006507106 A JP2006507106 A JP 2006507106A JP 2006522102 A JP2006522102 A JP 2006522102A
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cancer
imaging
molecule
pdt
molecules
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JP2006522102A5 (enExample
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チャールズ・ダブリュー・スパングラー
アレクサンダー・レバン
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MPA Technologies Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032Methine dyes, e.g. cyanine dyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/005Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0052Small organic molecules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2006507106A 2003-03-10 2004-03-10 光診断法および光線力学的療法の両方のためのターゲット剤 Pending JP2006522102A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45361803P 2003-03-10 2003-03-10
PCT/US2004/007525 WO2004080483A1 (en) 2003-03-10 2004-03-10 Targeted agents for both photodiagnosis and photodynamic therapy

Publications (2)

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JP2006522102A true JP2006522102A (ja) 2006-09-28
JP2006522102A5 JP2006522102A5 (enExample) 2007-04-26

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JP2006507106A Pending JP2006522102A (ja) 2003-03-10 2004-03-10 光診断法および光線力学的療法の両方のためのターゲット剤

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US (1) US20040247527A1 (enExample)
EP (1) EP1613351A1 (enExample)
JP (1) JP2006522102A (enExample)
AU (1) AU2004220530A1 (enExample)
CA (1) CA2523605A1 (enExample)
WO (1) WO2004080483A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012512184A (ja) * 2008-12-16 2012-05-31 キュー エル ティー インク. 眼の状態に関する光線力学的療法

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US7354433B2 (en) * 2003-02-28 2008-04-08 Advanced Light Technologies, Llc Disinfection, destruction of neoplastic growth, and sterilization by differential absorption of electromagnetic energy
US20110040295A1 (en) * 2003-02-28 2011-02-17 Photometics, Inc. Cancer treatment using selective photo-apoptosis
BRPI0519754A2 (pt) 2005-01-13 2009-03-10 Cinv Ag materiais compàsitos contendo nanopartÍculas de carbono
US20080268013A1 (en) * 2005-02-10 2008-10-30 Emory University Polyethylene Oxide Polymers Including Anti-Inflammatory Glycodendrons
US20080070802A1 (en) * 2006-08-23 2008-03-20 Moerschell Richard P Directed heterobifunctional linkers
US20090035576A1 (en) * 2006-09-08 2009-02-05 Prasad Paras N Nanoparticles for two-photon activated photodynamic therapy and imaging
US20080233051A1 (en) * 2006-09-08 2008-09-25 Prasad Paras N Nanoparticles for two-photon activated photodynamic therapy and imaging
JP2010519320A (ja) * 2007-02-28 2010-06-03 サノフィ−アベンティス イメージングプローブ
US20090069673A1 (en) * 2007-03-16 2009-03-12 The Charles Stark Draper Laboratory, Inc. Spinal needle optical sensor
WO2011037622A1 (en) * 2009-09-22 2011-03-31 Photometics Cancer treatment using selective photo-apoptosis
US8492339B2 (en) * 2009-10-26 2013-07-23 Empire Technology Development Llc Angiogenesis promoted by caged growth factors
WO2012176023A1 (en) 2011-06-23 2012-12-27 Indian Institute Of Technology Kanpur Hydrogel scaffolds for tissue engineering
AU2015284236B2 (en) 2014-06-30 2018-03-08 Tva (Abc), Llc Targeted conjugates and particles and formulations thereof
WO2016054079A1 (en) 2014-09-29 2016-04-07 Zyomed Corp. Systems and methods for blood glucose and other analyte detection and measurement using collision computing
EP3368546A4 (en) * 2015-10-28 2019-06-26 Tarveda Therapeutics, Inc. AGAINST SSTR CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing

Citations (5)

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WO2001052746A1 (en) * 2000-01-18 2001-07-26 Mallinckrodt Inc. Versatile hydrophilic dyes
US20020156117A1 (en) * 2000-01-18 2002-10-24 Mallinckrodt Inc. Receptor-avid exogenous optical contrast and therapeutic agents
WO2003003806A2 (en) * 2001-07-03 2003-01-16 Mallinckrodt, Inc. Dye-azide compounds for dual phototherapy
WO2003004466A2 (en) * 2001-07-03 2003-01-16 Mallinckrodt Inc. Dye-sulfenates for dual phototherapy
WO2003011106A2 (en) * 2001-07-31 2003-02-13 Mallinckrodt Inc. Internal image antibodies for optical imaging and therapy

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US6493570B1 (en) * 1998-11-02 2002-12-10 Photogen, Inc. Method for improved imaging and photodynamic therapy
US5832931A (en) * 1996-10-30 1998-11-10 Photogen, Inc. Method for improved selectivity in photo-activation and detection of molecular diagnostic agents
US6217848B1 (en) * 1999-05-20 2001-04-17 Mallinckrodt Inc. Cyanine and indocyanine dye bioconjugates for biomedical applications
AU2002332608B2 (en) * 2001-08-22 2008-05-15 Montana State University-Bozeman Porphyrins with enhanced multi-photon absorption cross-sections for photodynamic therapy
US20030105300A1 (en) * 2001-10-17 2003-06-05 Mallinckrodt Inc. Tumor targeted photodiagnostic-phototherapeutic agents
US6761878B2 (en) * 2001-10-17 2004-07-13 Mallinckrodt, Inc. Pathological tissue detection and treatment employing targeted benzoindole optical agents
US20030105299A1 (en) * 2001-10-17 2003-06-05 Mallinckrodt Inc. Carbocyanine dyes for tandem, photodiagnostic and therapeutic applications
US20030152577A1 (en) * 2002-02-07 2003-08-14 Mallinckrodt Inc. Dye-bioconjugates for simultaneous optical diagnostic and therapeutic applications

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001052746A1 (en) * 2000-01-18 2001-07-26 Mallinckrodt Inc. Versatile hydrophilic dyes
US20020156117A1 (en) * 2000-01-18 2002-10-24 Mallinckrodt Inc. Receptor-avid exogenous optical contrast and therapeutic agents
WO2003003806A2 (en) * 2001-07-03 2003-01-16 Mallinckrodt, Inc. Dye-azide compounds for dual phototherapy
WO2003004466A2 (en) * 2001-07-03 2003-01-16 Mallinckrodt Inc. Dye-sulfenates for dual phototherapy
WO2003011106A2 (en) * 2001-07-31 2003-02-13 Mallinckrodt Inc. Internal image antibodies for optical imaging and therapy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012512184A (ja) * 2008-12-16 2012-05-31 キュー エル ティー インク. 眼の状態に関する光線力学的療法

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Publication number Publication date
US20040247527A1 (en) 2004-12-09
AU2004220530A1 (en) 2004-09-23
CA2523605A1 (en) 2004-09-23
WO2004080483A1 (en) 2004-09-23
EP1613351A1 (en) 2006-01-11

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