JP2006521813A - Ｐｉ３−キナーゼの調節剤を用いた再生可能な幹細胞集団の拡大 - Google Patents

Ｐｉ３−キナーゼの調節剤を用いた再生可能な幹細胞集団の拡大 Download PDF

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JP2006521813A
JP2006521813A JP2006507579A JP2006507579A JP2006521813A JP 2006521813 A JP2006521813 A JP 2006521813A JP 2006507579 A JP2006507579 A JP 2006507579A JP 2006507579 A JP2006507579 A JP 2006507579A JP 2006521813 A JP2006521813 A JP 2006521813A
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cells
kinase
cell
stem
stem cell
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JP2006521813A5 (enExample
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トニー ペレド，
フリダ グリンスパン，
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ガミダ セル リミテッド
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JP2006507579A 2003-03-07 2004-03-04 Ｐｉ３−キナーゼの調節剤を用いた再生可能な幹細胞集団の拡大 Pending JP2006521813A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US45254503P 2003-03-07 2003-03-07
PCT/IL2003/000235 WO2003078567A2 (en) 2002-03-18 2003-03-18 Methods of inducing differentiation in ex vivo expanded stem cells
PCT/IL2003/000681 WO2004016731A2 (en) 2002-08-19 2003-08-17 Ex-vivo expansion of hematopoietic stem cell populations in mononuclear cell cultures
PCT/IL2004/000215 WO2004078917A2 (en) 2003-03-07 2004-03-04 Expansion of renewable stem cell populations using modulators of pi 3-kinase

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JP2006521813A true JP2006521813A (ja) 2006-09-28
JP2006521813A5 JP2006521813A5 (enExample) 2007-03-01

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US (1) US20050054103A1 (enExample)
EP (1) EP1601759A4 (enExample)
JP (1) JP2006521813A (enExample)
AU (1) AU2004217699B2 (enExample)
CA (1) CA2517959A1 (enExample)
WO (1) WO2004078917A2 (enExample)
ZA (1) ZA200507161B (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005528088A (ja) * 2002-01-24 2005-09-22 ガミダ セル リミテッド 再生可能な幹細胞集団の拡大
JP2010524499A (ja) * 2007-04-23 2010-07-22 ストワーズ インスティテュート フォー メディカル リサーチ 幹細胞自己複製のための方法及び組成物
WO2014098232A1 (ja) * 2012-12-21 2014-06-26 Yamashita Chikamasa Ｐｉ３キナーゼ阻害剤を含む医薬組成物、ビタミンｄ受容体に作用する化合物を含む医薬組成物、凍結乾燥組成物、凍結乾燥組成物の製造方法、及び経肺投与用医薬組成物
JP2015000064A (ja) * 2013-06-17 2015-01-05 ホン ガオＨｏｎｇ Ｇａｏ 造血幹細胞の増殖方法
JP2019516738A (ja) * 2016-05-20 2019-06-20 オスペダーレ サン ラファエレ エス．アール．エル 遺伝子治療

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US7691821B2 (en) * 2001-09-19 2010-04-06 University Of South Florida Inhibition of SHIP to enhance stem cell harvest and transplantation
EP1465982A4 (en) 2002-01-25 2006-06-07 Gamida Cell Ltd PROCESS FOR EXPANSION OF STEM AND PRESERVATIVE CELLS AND EXPANDED CELL POPULATIONS THEREWITH OBTAINED
US20070224124A1 (en) * 2002-09-30 2007-09-27 University Of South Florida Novel SH2containing inositol 5'-phosphatase isoform that partners with the Grb2 adapter protein
US7807646B1 (en) * 2003-11-20 2010-10-05 University Of South Florida SHIP-deficiency to increase megakaryocyte progenitor production
US7763592B1 (en) 2003-11-20 2010-07-27 University Of South Florida SHIP-deficiency to increase megakaryocyte progenitor production
WO2006030442A2 (en) * 2004-09-16 2006-03-23 Gamida-Cell Ltd. Methods of ex vivo progenitor and stem cell expansion by co-culture with mesenchymal cells
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
EP1974012B1 (en) * 2005-11-29 2013-02-27 Gamida Cell Ltd. Methods of improving stem cell homing and engraftment
RU2425876C2 (ru) * 2006-03-24 2011-08-10 Чилдрен'З Медикал Сентер Корпорейшн Способ модулирования роста гематопоэтических стволовых клеток
EP2679221B1 (en) 2006-10-20 2020-09-23 Children's Medical Center Corporation Method to enhance tissue regeneration
WO2008089351A1 (en) * 2007-01-17 2008-07-24 Wisconsin Alumni Research Foundation Improved culture of stem cells
US20100136026A1 (en) * 2007-09-26 2010-06-03 Kerr William G Ship Inhibition to Direct Hematopoietic Stem Cells and Induce Extramedullary Hematopoiesis
KR100985832B1 (ko) * 2008-01-03 2010-10-08 한양대학교 산학협력단 인간 배아 줄기세포 배양방법
US8082730B2 (en) * 2008-05-20 2011-12-27 Caterpillar Inc. Engine system having particulate reduction device and method
WO2009155041A2 (en) * 2008-05-28 2009-12-23 Children's Medical Center Corporation Method to modulate hematopoietic stem cell growth
WO2010096264A2 (en) 2009-02-03 2010-08-26 Children's Medical Center Corporation Methods for enhancing hematopoietic stem/progenitor cell engraftment
WO2010091052A2 (en) 2009-02-03 2010-08-12 Children's Medical Center Corporation Methods for enhancing hematopoietic stem/progenitor cell engraftment
PT2785834T (pt) 2011-12-02 2020-11-13 Fate Therapeutics Inc Composição de células estaminais melhorada
EP2785350B1 (en) 2011-12-02 2018-05-02 Fate Therapeutics, Inc. Improved methods of treating ischemia
JP6348848B2 (ja) 2012-02-13 2018-06-27 ガミダ セル リミテッド 間葉系幹細胞の増殖
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
US10851412B2 (en) 2013-03-15 2020-12-01 Fate Therapeutics, Inc. Cell potency assay for therapeutic potential
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EP3630830A1 (en) * 2017-05-23 2020-04-08 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Novel cd73 antibody, preparation and uses thereof
KR102791660B1 (ko) 2017-12-22 2025-04-08 페이트 세러퓨틱스, 인코포레이티드 향상된 면역 효과기 세포 및 이의 용도
CN115161282A (zh) * 2022-07-22 2022-10-11 邓超 一种小鼠脑微血管内皮细胞与周细胞联合提取培养方法

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