JP2006521813A5 - - Google Patents
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- Publication number
- JP2006521813A5 JP2006521813A5 JP2006507579A JP2006507579A JP2006521813A5 JP 2006521813 A5 JP2006521813 A5 JP 2006521813A5 JP 2006507579 A JP2006507579 A JP 2006507579A JP 2006507579 A JP2006507579 A JP 2006507579A JP 2006521813 A5 JP2006521813 A5 JP 2006521813A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- kinase
- hematopoietic
- stem cells
- stem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000430 Phosphatidylinositol 3-kinases Proteins 0.000 claims 43
- 102000003993 Phosphatidylinositol 3-kinases Human genes 0.000 claims 43
- 238000000034 method Methods 0.000 claims 41
- 210000003958 hematopoietic stem cell Anatomy 0.000 claims 30
- 210000000130 stem cell Anatomy 0.000 claims 28
- 210000004027 cell Anatomy 0.000 claims 18
- 108090000695 Cytokines Proteins 0.000 claims 16
- 102000004127 Cytokines Human genes 0.000 claims 16
- 230000000694 effects Effects 0.000 claims 14
- 108090000623 proteins and genes Proteins 0.000 claims 11
- 230000002222 downregulating effect Effects 0.000 claims 9
- 230000004069 differentiation Effects 0.000 claims 8
- 230000002401 inhibitory effect Effects 0.000 claims 6
- 230000010261 cell growth Effects 0.000 claims 5
- 108090000994 Catalytic RNA Proteins 0.000 claims 4
- 102000053642 Catalytic RNA Human genes 0.000 claims 4
- 108020004414 DNA Proteins 0.000 claims 4
- 108091027757 Deoxyribozyme Proteins 0.000 claims 4
- 108020004459 Small interfering RNA Proteins 0.000 claims 4
- 230000000692 anti-sense effect Effects 0.000 claims 4
- 210000002449 bone cell Anatomy 0.000 claims 4
- 210000001185 bone marrow Anatomy 0.000 claims 4
- 230000015556 catabolic process Effects 0.000 claims 4
- 230000003197 catalytic effect Effects 0.000 claims 4
- 210000001612 chondrocyte Anatomy 0.000 claims 4
- 238000006731 degradation reaction Methods 0.000 claims 4
- 210000001671 embryonic stem cell Anatomy 0.000 claims 4
- 210000004700 fetal blood Anatomy 0.000 claims 4
- 230000003394 haemopoietic effect Effects 0.000 claims 4
- 210000003494 hepatocyte Anatomy 0.000 claims 4
- 230000001939 inductive effect Effects 0.000 claims 4
- 239000003112 inhibitor Substances 0.000 claims 4
- 108020004999 messenger RNA Proteins 0.000 claims 4
- 210000000663 muscle cell Anatomy 0.000 claims 4
- 210000002569 neuron Anatomy 0.000 claims 4
- 235000015097 nutrients Nutrition 0.000 claims 4
- 210000004248 oligodendroglia Anatomy 0.000 claims 4
- 210000005259 peripheral blood Anatomy 0.000 claims 4
- 239000011886 peripheral blood Substances 0.000 claims 4
- 108091033319 polynucleotide Proteins 0.000 claims 4
- 102000040430 polynucleotide Human genes 0.000 claims 4
- 239000002157 polynucleotide Substances 0.000 claims 4
- 108091092562 ribozyme Proteins 0.000 claims 4
- 210000004927 skin cell Anatomy 0.000 claims 4
- 210000002536 stromal cell Anatomy 0.000 claims 4
- 230000004663 cell proliferation Effects 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 230000002463 transducing effect Effects 0.000 claims 2
- 239000001963 growth medium Substances 0.000 claims 1
- 238000009169 immunotherapy Methods 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 239000002609 medium Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45254503P | 2003-03-07 | 2003-03-07 | |
| PCT/IL2003/000235 WO2003078567A2 (en) | 2002-03-18 | 2003-03-18 | Methods of inducing differentiation in ex vivo expanded stem cells |
| PCT/IL2003/000681 WO2004016731A2 (en) | 2002-08-19 | 2003-08-17 | Ex-vivo expansion of hematopoietic stem cell populations in mononuclear cell cultures |
| PCT/IL2004/000215 WO2004078917A2 (en) | 2003-03-07 | 2004-03-04 | Expansion of renewable stem cell populations using modulators of pi 3-kinase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006521813A JP2006521813A (ja) | 2006-09-28 |
| JP2006521813A5 true JP2006521813A5 (enExample) | 2007-03-01 |
Family
ID=35261937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006507579A Pending JP2006521813A (ja) | 2003-03-07 | 2004-03-04 | Pi3−キナーゼの調節剤を用いた再生可能な幹細胞集団の拡大 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20050054103A1 (enExample) |
| EP (1) | EP1601759A4 (enExample) |
| JP (1) | JP2006521813A (enExample) |
| AU (1) | AU2004217699B2 (enExample) |
| CA (1) | CA2517959A1 (enExample) |
| WO (1) | WO2004078917A2 (enExample) |
| ZA (1) | ZA200507161B (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7569342B2 (en) * | 1997-12-10 | 2009-08-04 | Sierra Molecular Corp. | Removal of molecular assay interferences |
| US20080064108A1 (en) * | 1997-12-10 | 2008-03-13 | Tony Baker | Urine Preservation System |
| AU770896C (en) | 1998-09-29 | 2006-09-07 | Gamida Cell Ltd. | Methods of controlling proliferation and differentiation of stem and progenitor cells |
| US20020165192A1 (en) | 2000-09-19 | 2002-11-07 | Kerr William G. | Control of NK cell function and survival by modulation of ship activity |
| US7691821B2 (en) * | 2001-09-19 | 2010-04-06 | University Of South Florida | Inhibition of SHIP to enhance stem cell harvest and transplantation |
| WO2009042910A2 (en) * | 2007-09-26 | 2009-04-02 | University Of South Florida | Ship inhibition to direct hematopoietic stem cells and induce extramedullary hematopoiesis |
| IL152904A0 (en) | 2002-01-24 | 2003-06-24 | Gamida Cell Ltd | Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations |
| WO2003062404A1 (en) | 2002-01-25 | 2003-07-31 | Gamida-Cell Ltd. | Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby |
| US20070224124A1 (en) * | 2002-09-30 | 2007-09-27 | University Of South Florida | Novel SH2containing inositol 5'-phosphatase isoform that partners with the Grb2 adapter protein |
| US7807646B1 (en) * | 2003-11-20 | 2010-10-05 | University Of South Florida | SHIP-deficiency to increase megakaryocyte progenitor production |
| US7763592B1 (en) | 2003-11-20 | 2010-07-27 | University Of South Florida | SHIP-deficiency to increase megakaryocyte progenitor production |
| EP1799812A4 (en) * | 2004-09-16 | 2009-09-09 | Gamida Cell Ltd | EX VIVO CULTIVATION METHODS OF STEM CELLS AND PRECURSOR BY CO-CULTURE WITH MESENCHYMAL CELLS |
| EP2390312A1 (en) * | 2005-11-29 | 2011-11-30 | Gamida Cell Ltd. | Methods of improving stem cell homing and engraftment |
| US8846393B2 (en) | 2005-11-29 | 2014-09-30 | Gamida-Cell Ltd. | Methods of improving stem cell homing and engraftment |
| RU2493252C2 (ru) * | 2006-03-24 | 2013-09-20 | Чилдрен'З Медикал Сентер Корпорейшн | Способ стимулирования экспансии гематопоэтических стволовых клеток |
| RU2480213C2 (ru) * | 2006-10-20 | 2013-04-27 | Чилдрен'З Медикал Сентер Корпорейшн | Способ стимуляции регенерации тканей |
| WO2008089351A1 (en) * | 2007-01-17 | 2008-07-24 | Wisconsin Alumni Research Foundation | Improved culture of stem cells |
| US8263403B2 (en) * | 2007-04-23 | 2012-09-11 | Stowers Institute For Medical Research | Methods and compositions for stem cell self-renewal |
| KR100985832B1 (ko) * | 2008-01-03 | 2010-10-08 | 한양대학교 산학협력단 | 인간 배아 줄기세포 배양방법 |
| US8082730B2 (en) * | 2008-05-20 | 2011-12-27 | Caterpillar Inc. | Engine system having particulate reduction device and method |
| WO2009155041A2 (en) * | 2008-05-28 | 2009-12-23 | Children's Medical Center Corporation | Method to modulate hematopoietic stem cell growth |
| WO2010091052A2 (en) | 2009-02-03 | 2010-08-12 | Children's Medical Center Corporation | Methods for enhancing hematopoietic stem/progenitor cell engraftment |
| US9056085B2 (en) | 2009-02-03 | 2015-06-16 | Children's Medical Center Corporation | Methods for enhancing hematopoietic stem/progenitor cell engraftment |
| AU2012321088B8 (en) | 2011-12-02 | 2016-12-15 | Fate Therapeutics, Inc. | Enhanced stem cell composition |
| ES2682255T3 (es) | 2011-12-02 | 2018-09-19 | Fate Therapeutics, Inc. | Métodos mejorados de tratamiento de isquemia |
| US20150064273A1 (en) | 2012-02-13 | 2015-03-05 | Gamida-Cell Ltd. | Mesenchymal Stem Cells Conditioned Medium and Methods of Generating and Using the Same |
| US9175266B2 (en) | 2012-07-23 | 2015-11-03 | Gamida Cell Ltd. | Enhancement of natural killer (NK) cell proliferation and activity |
| US9567569B2 (en) | 2012-07-23 | 2017-02-14 | Gamida Cell Ltd. | Methods of culturing and expanding mesenchymal stem cells |
| WO2014098232A1 (ja) * | 2012-12-21 | 2014-06-26 | Yamashita Chikamasa | Pi3キナーゼ阻害剤を含む医薬組成物、ビタミンd受容体に作用する化合物を含む医薬組成物、凍結乾燥組成物、凍結乾燥組成物の製造方法、及び経肺投与用医薬組成物 |
| EP2968416A4 (en) | 2013-03-15 | 2016-08-17 | Fate Therapeutics Inc | CELL POTENTIAL TEST FOR THERAPEUTIC POTENTIAL |
| US9428748B2 (en) * | 2013-06-17 | 2016-08-30 | Hong Gao | Method of expanding hematopoietic stem cells |
| EP3567100A1 (en) * | 2014-11-07 | 2019-11-13 | Osaka University | Differentiation-induced cell population from which undifferentiated cells have been removed, use of same, and method for producing same |
| GB201608944D0 (en) | 2016-05-20 | 2016-07-06 | Ospedale San Raffaele And Fond Telethon | Gene Tharapy |
| CN110753703B (zh) * | 2017-05-23 | 2024-04-09 | 德国亥姆霍兹慕尼黑中心健康与环境研究中心(有限公司) | 新的cd73抗体、其制备和用途 |
| ES3037765T3 (en) | 2017-12-22 | 2025-10-07 | Fate Therapeutics Inc | Enhanced immune effector cells and use thereof |
| CN115161282A (zh) * | 2022-07-22 | 2022-10-11 | 邓超 | 一种小鼠脑微血管内皮细胞与周细胞联合提取培养方法 |
Family Cites Families (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154600B (nl) * | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
| US3715345A (en) * | 1970-08-03 | 1973-02-06 | Lilly Co Eli | Glucagon separation process |
| NL154598B (nl) * | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| NL154599B (nl) * | 1970-12-28 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking. |
| US3901654A (en) * | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
| US3853987A (en) * | 1971-09-01 | 1974-12-10 | W Dreyer | Immunological reagent and radioimmuno assay |
| US3936074A (en) * | 1971-12-16 | 1976-02-03 | Ernesto Prinoth | Vehicle chassis |
| US3867517A (en) * | 1971-12-21 | 1975-02-18 | Abbott Lab | Direct radioimmunoassay for antigens and their antibodies |
| US3850578A (en) * | 1973-03-12 | 1974-11-26 | H Mcconnell | Process for assaying for biologically active molecules |
| US3876623A (en) * | 1973-05-09 | 1975-04-08 | Lilly Co Eli | Process for purifying insulin |
| US3863008A (en) * | 1973-06-11 | 1975-01-28 | American Home Prod | Somatostatin as stimulant of luteinizing hormone secretion |
| US3935074A (en) * | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
| US3996345A (en) * | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4034074A (en) * | 1974-09-19 | 1977-07-05 | The Board Of Trustees Of Leland Stanford Junior University | Universal reagent 2-site immunoradiometric assay using labelled anti (IgG) |
| US3984533A (en) * | 1975-11-13 | 1976-10-05 | General Electric Company | Electrophoretic method of detecting antigen-antibody reaction |
| US4098876A (en) * | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
| US4879219A (en) * | 1980-09-19 | 1989-11-07 | General Hospital Corporation | Immunoassay utilizing monoclonal high affinity IgM antibodies |
| IL68218A (en) * | 1983-03-23 | 1985-12-31 | Univ Ramot | Compositions for cartilage repair comprising embryonal chondrocytes |
| US5011771A (en) * | 1984-04-12 | 1991-04-30 | The General Hospital Corporation | Multiepitopic immunometric assay |
| US4666828A (en) * | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4801531A (en) * | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
| US4806484A (en) * | 1987-08-07 | 1989-02-21 | Igb Products, Ltd. | Perfusion airlift bioreactor |
| US5081035A (en) * | 1988-04-18 | 1992-01-14 | The University Of Michigan | Bioreactor system |
| US5272057A (en) * | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5437994A (en) * | 1989-06-15 | 1995-08-01 | Regents Of The University Of Michigan | Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells |
| US5192659A (en) * | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
| US5612211A (en) * | 1990-06-08 | 1997-03-18 | New York University | Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors |
| US6326198B1 (en) * | 1990-06-14 | 2001-12-04 | Regents Of The University Of Michigan | Methods and compositions for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells |
| US5486359A (en) * | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| US5281521A (en) * | 1992-07-20 | 1994-01-25 | The Trustees Of The University Of Pennsylvania | Modified avidin-biotin technique |
| US5320963A (en) * | 1992-11-25 | 1994-06-14 | National Research Council Of Canada | Bioreactor for the perfusion culture of cells |
| US5654186A (en) * | 1993-02-26 | 1997-08-05 | The Picower Institute For Medical Research | Blood-borne mesenchymal cells |
| US5342781A (en) * | 1993-07-15 | 1994-08-30 | Su Wei Wen W | External-loop perfusion air-lift bioreactor |
| US5378725A (en) * | 1993-07-19 | 1995-01-03 | The Arizona Board Of Regents | Inhibition of phosphatidylinositol 3-kinase with wortmannin and analogs thereof |
| US5504103A (en) * | 1993-08-25 | 1996-04-02 | Eli Lilly And Company | Inhibition of phosphatidylinositol 3-kinase with 17 β-hydroxywortmannin and analogs thereof |
| US5489304A (en) * | 1994-04-19 | 1996-02-06 | Brigham & Women's Hospital | Method of skin regeneration using a collagen-glycosaminoglycan matrix and cultured epithelial autograft |
| US5480906A (en) * | 1994-07-01 | 1996-01-02 | Eli Lilly And Company | Stereochemical Wortmannin derivatives |
| US5736396A (en) * | 1995-01-24 | 1998-04-07 | Case Western Reserve University | Lineage-directed induction of human mesenchymal stem cell differentiation |
| US5716616A (en) * | 1995-03-28 | 1998-02-10 | Thomas Jefferson University | Isolated stromal cells for treating diseases, disorders or conditions characterized by bone defects |
| US5674750A (en) * | 1995-05-19 | 1997-10-07 | T. Breeders | Continuous selective clonogenic expansion of relatively undifferentiated cells |
| US5712154A (en) * | 1995-06-07 | 1998-01-27 | W.R. Grace & Co.-Conn. | Dual fiber bioreactor |
| US6680166B1 (en) * | 1995-06-07 | 2004-01-20 | Claudy Jean Paul Mullon | Dual fiber bioreactor |
| US6043092A (en) * | 1996-03-18 | 2000-03-28 | University Of Pittsburgh | Cell culture media for mammalian cells |
| US5945337A (en) * | 1996-10-18 | 1999-08-31 | Quality Biological, Inc. | Method for culturing CD34+ cells in a serum-free medium |
| US6335195B1 (en) * | 1997-01-28 | 2002-01-01 | Maret Corporation | Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation |
| US20030215445A1 (en) * | 1997-05-23 | 2003-11-20 | Ginette Serrero | Methods and compositions for inhibiting the growth of hematopoietic malignant cells |
| DE29712121U1 (de) * | 1997-07-10 | 1997-09-11 | Sigma Laborzentrifugen Gmbh, 37520 Osterode | Steuerungseinrichtung für eine Laborzentrifuge |
| US6440734B1 (en) * | 1998-09-25 | 2002-08-27 | Cytomatrix, Llc | Methods and devices for the long-term culture of hematopoietic progenitor cells |
| AU770896C (en) * | 1998-09-29 | 2006-09-07 | Gamida Cell Ltd. | Methods of controlling proliferation and differentiation of stem and progenitor cells |
| US6962698B1 (en) * | 1998-02-17 | 2005-11-08 | Gamida Cell Ltd. | Methods of controlling proliferation and differentiation of stem and progenitor cells |
| EP1069821B1 (en) * | 1998-02-17 | 2011-06-08 | Gamida Cell Ltd. | Method of controlling proliferation and differentiation of stem and progenitor cells |
| US6413773B1 (en) * | 1998-06-01 | 2002-07-02 | The Regents Of The University Of California | Phosphatidylinositol 3-kinase inhibitors as stimulators of endocrine differentiation |
| EP2314700A1 (en) * | 1999-01-28 | 2011-04-27 | Medical College of Georgia Research Institute, Inc | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA |
| US6303374B1 (en) * | 2000-01-18 | 2001-10-16 | Isis Pharmaceuticals Inc. | Antisense modulation of caspase 3 expression |
| US6642019B1 (en) * | 2000-11-22 | 2003-11-04 | Synthecan, Inc. | Vessel, preferably spherical or oblate spherical for growing or culturing cells, cellular aggregates, tissues and organoids and methods for using same |
| DE10103402B4 (de) * | 2001-01-26 | 2005-11-24 | Daimlerchrysler Ag | Außenrückblickspiegel eines Kraftfahrzeugs |
| US6908932B2 (en) * | 2001-10-24 | 2005-06-21 | Iconix Pharmaceuticals, Inc. | Modulators of phosphoinositide 3-kinase |
| WO2003062404A1 (en) * | 2002-01-25 | 2003-07-31 | Gamida-Cell Ltd. | Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby |
| US20050220774A1 (en) * | 2002-03-18 | 2005-10-06 | Tony Peled | Methods of inducing differentiation in ex vivo expanded stem cells |
| US7247477B2 (en) * | 2002-04-16 | 2007-07-24 | Technion Research & Development Foundation Ltd. | Methods for the in-vitro identification, isolation and differentiation of vasculogenic progenitor cells |
| WO2004016731A2 (en) * | 2002-08-19 | 2004-02-26 | Gamida-Cell Ltd. | Ex-vivo expansion of hematopoietic stem cell populations in mononuclear cell cultures |
-
2004
- 2004-03-04 AU AU2004217699A patent/AU2004217699B2/en not_active Ceased
- 2004-03-04 JP JP2006507579A patent/JP2006521813A/ja active Pending
- 2004-03-04 US US10/795,215 patent/US20050054103A1/en not_active Abandoned
- 2004-03-04 EP EP04717214A patent/EP1601759A4/en not_active Withdrawn
- 2004-03-04 WO PCT/IL2004/000215 patent/WO2004078917A2/en not_active Ceased
- 2004-03-04 CA CA002517959A patent/CA2517959A1/en not_active Abandoned
-
2005
- 2005-09-06 ZA ZA200507161A patent/ZA200507161B/xx unknown
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