JP2006520797A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006520797A5 JP2006520797A5 JP2006507344A JP2006507344A JP2006520797A5 JP 2006520797 A5 JP2006520797 A5 JP 2006520797A5 JP 2006507344 A JP2006507344 A JP 2006507344A JP 2006507344 A JP2006507344 A JP 2006507344A JP 2006520797 A5 JP2006520797 A5 JP 2006520797A5
- Authority
- JP
- Japan
- Prior art keywords
- formulation
- propellant
- ethanol
- water
- mass
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 15
- 238000009472 formulation Methods 0.000 claims 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 8
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 6
- 239000003380 propellant Substances 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 4
- 229940057282 albuterol sulfate Drugs 0.000 claims 2
- BNPSSFBOAGDEEL-UHFFFAOYSA-N albuterol sulfate Chemical compound OS(O)(=O)=O.CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1.CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 BNPSSFBOAGDEEL-UHFFFAOYSA-N 0.000 claims 2
- 239000012141 concentrate Substances 0.000 claims 2
- KEWHKYJURDBRMN-ZEODDXGYSA-M ipratropium bromide hydrate Chemical compound O.[Br-].O([C@H]1C[C@H]2CC[C@@H](C1)[N@@+]2(C)C(C)C)C(=O)C(CO)C1=CC=CC=C1 KEWHKYJURDBRMN-ZEODDXGYSA-M 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 2
- LVGUZGTVOIAKKC-UHFFFAOYSA-N 1,1,1,2-tetrafluoroethane Chemical group FCC(F)(F)F LVGUZGTVOIAKKC-UHFFFAOYSA-N 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 229960001361 ipratropium bromide Drugs 0.000 claims 1
- 229960002630 ipratropium bromide monohydrate Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229940071648 metered dose inhaler Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45611303P | 2003-03-20 | 2003-03-20 | |
| US60/456,113 | 2003-03-20 | ||
| PCT/US2004/008375 WO2004084858A2 (en) | 2003-03-20 | 2004-03-19 | Formulation for a metered dose inhaler using hydro-fluoro-alkanes as propellants |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006520797A JP2006520797A (ja) | 2006-09-14 |
| JP2006520797A5 true JP2006520797A5 (enExample) | 2007-05-17 |
| JP4708332B2 JP4708332B2 (ja) | 2011-06-22 |
Family
ID=33098086
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006507344A Expired - Lifetime JP4708332B2 (ja) | 2003-03-20 | 2004-03-19 | 推進剤としてヒドロフルオロアルカンを用いる計量式吸入器のための調合物 |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7914770B2 (enExample) |
| EP (1) | EP1608336B1 (enExample) |
| JP (1) | JP4708332B2 (enExample) |
| KR (1) | KR101113003B1 (enExample) |
| CN (1) | CN1761455A (enExample) |
| AT (1) | ATE390125T1 (enExample) |
| AU (1) | AU2004224367B2 (enExample) |
| BR (1) | BRPI0408547A (enExample) |
| CA (1) | CA2519523C (enExample) |
| CO (1) | CO5640070A2 (enExample) |
| CY (1) | CY1108137T1 (enExample) |
| DE (1) | DE602004012718T2 (enExample) |
| DK (1) | DK1608336T3 (enExample) |
| EA (1) | EA009087B1 (enExample) |
| EC (1) | ECSP056029A (enExample) |
| ES (1) | ES2304616T3 (enExample) |
| HR (1) | HRP20050822B1 (enExample) |
| ME (1) | ME00420B (enExample) |
| MX (1) | MXPA05009920A (enExample) |
| NO (1) | NO336457B1 (enExample) |
| NZ (1) | NZ542957A (enExample) |
| PL (1) | PL1608336T3 (enExample) |
| PT (1) | PT1608336E (enExample) |
| RS (1) | RS51663B (enExample) |
| SI (1) | SI1608336T1 (enExample) |
| UA (1) | UA89751C2 (enExample) |
| WO (1) | WO2004084858A2 (enExample) |
| ZA (1) | ZA200506463B (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004011381A1 (de) * | 2004-03-05 | 2005-09-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Impaktionsdüse für treibgasbetriebene Dosieraerosole |
| DK1809243T4 (da) * | 2004-07-02 | 2022-09-05 | Boehringer Ingelheim Int | Aerosolsuspensionsformuleringer med tg 227 ea som drivmiddel |
| US20060140873A1 (en) * | 2004-12-27 | 2006-06-29 | Chang Heng W | Aerosol pharmaceutical compositions |
| GB0501956D0 (en) * | 2005-01-31 | 2005-03-09 | Arrow Internat | Nebulizer formulation |
| GB0518769D0 (en) * | 2005-09-14 | 2005-10-19 | Medpharm Ltd | Topical formulations |
| DE102006053374A1 (de) * | 2006-02-09 | 2007-08-16 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen und mindestens einer oberflächenaktiven Substanz |
| DE102006014433A1 (de) | 2006-03-27 | 2007-10-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Dosieraerosole für die Verabreichung von pharmazeutischen Zubereitungen |
| DE102006017320A1 (de) * | 2006-04-11 | 2007-10-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel |
| WO2008047239A2 (en) * | 2006-09-21 | 2008-04-24 | Medispray Laboratories Pvt. Ltd. | Stable aerosol pharmaceutical formulations |
| JP5358574B2 (ja) * | 2007-08-17 | 2013-12-04 | アルション セラピューティクス， インコーポレイテッド | 高濃度の局所麻酔薬調合物 |
| EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
| US8119694B2 (en) | 2008-08-15 | 2012-02-21 | Arcion Therapeutics, Inc. | High concentration local anesthetic formulations |
| WO2010112358A2 (de) | 2009-03-31 | 2010-10-07 | Boehringer Ingelheim International Gmbh | Verfahren zur beschichtung einer oberfläche eines bauteils |
| WO2010133294A2 (de) | 2009-05-18 | 2010-11-25 | Boehringer Ingelheim International Gmbh | Adapter, inhalationseinrichtung und zerstäuber |
| EP2504051B1 (en) | 2009-11-25 | 2019-09-04 | Boehringer Ingelheim International GmbH | Nebulizer |
| US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
| EA026241B1 (ru) | 2009-11-25 | 2017-03-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Распылитель |
| JP5874724B2 (ja) | 2010-06-24 | 2016-03-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
| US20120204871A1 (en) * | 2011-02-10 | 2012-08-16 | Julio Cesar Vega | Stable, non-corrosive formulations for pressurized metered dose inhalers |
| EP2694220B1 (de) | 2011-04-01 | 2020-05-06 | Boehringer Ingelheim International GmbH | Medizinisches gerät mit behälter |
| US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
| CN102798044B (zh) * | 2012-08-02 | 2014-09-10 | 深圳市华星光电技术有限公司 | 侧入式背光模组 |
| EP3030298B1 (en) | 2013-08-09 | 2017-10-11 | Boehringer Ingelheim International GmbH | Nebulizer |
| PL2835146T3 (pl) | 2013-08-09 | 2021-04-06 | Boehringer Ingelheim International Gmbh | Nebulizator |
| EA033013B1 (ru) | 2014-05-07 | 2019-08-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Контейнер, индикаторное устройство и небулайзер |
| EP3139984B1 (en) | 2014-05-07 | 2021-04-28 | Boehringer Ingelheim International GmbH | Nebulizer |
| AU2015257878B2 (en) | 2014-05-07 | 2019-08-08 | Boehringer Ingelheim International Gmbh | Container, nebulizer and use |
| EP3280393A1 (en) * | 2015-04-10 | 2018-02-14 | 3M Innovative Properties Company | Formulation and aerosol canisters, inhalers, and the like containing the formulation |
| GB2573297A (en) * | 2018-04-30 | 2019-11-06 | Mexichem Fluor Sa De Cv | Pharmaceutical composition |
| WO2021216779A1 (en) * | 2020-04-21 | 2021-10-28 | Amphastar Pharmaceuticals, Inc. | Anti-viral pharmaceutical formulations administered via devices for lung targeted delivery |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4405598A (en) * | 1976-01-30 | 1983-09-20 | Fisons, Limited | Composition for treating asthma |
| GB8824804D0 (en) | 1988-10-22 | 1988-11-30 | Fisons Plc | Device |
| US5225183A (en) | 1988-12-06 | 1993-07-06 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
| US5919435A (en) | 1990-11-09 | 1999-07-06 | Glaxo Group Limited | Aerosol formulation containing a particulate medicament |
| GB9202519D0 (en) * | 1992-02-06 | 1992-03-25 | Glaxo Group Ltd | Medicaments |
| JP3009924B2 (ja) * | 1992-12-09 | 2000-02-14 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | 安定化医用エアーゾル溶液製剤 |
| EP0960830A1 (en) | 1993-04-30 | 1999-12-01 | Minnesota Mining And Manufacturing Company | Seal configuration for aerosol canister |
| AU680530B2 (en) | 1993-07-15 | 1997-07-31 | Minnesota Mining And Manufacturing Company | Seals for use in an aerosol delivery device |
| BR9604979A (pt) * | 1995-04-14 | 1998-06-09 | Glaxo Wellcome Inc | Inalador de dose medida sistema inalador de dose medida e uso do mesmo |
| GB9513084D0 (en) | 1995-06-27 | 1995-08-30 | Bespak Plc | Dispensing apparatus |
| SE9701750D0 (sv) | 1997-05-12 | 1997-05-12 | Astra Pharma Prod | Inhalation device and method of manufacture thereof |
| US20010031244A1 (en) | 1997-06-13 | 2001-10-18 | Chiesi Farmaceutici S.P.A. | Pharmaceutical aerosol composition |
| GB2326334A (en) * | 1997-06-13 | 1998-12-23 | Chiesi Farma Spa | Pharmaceutical aerosol compositions |
| US6423298B2 (en) * | 1998-06-18 | 2002-07-23 | Boehringer Ingelheim Pharmaceuticals, Inc. | Pharmaceutical formulations for aerosols with two or more active substances |
| DK1102579T3 (da) * | 1998-08-04 | 2003-07-14 | Jago Res Ag | Medicinske aerosolformuleringer |
| DZ2947A1 (fr) | 1998-11-25 | 2004-03-15 | Chiesi Farma Spa | Inhalateur à compteur de dose sous pression. |
| IT1303788B1 (it) | 1998-11-25 | 2001-02-23 | Chiesi Farma Spa | Formulazioni di aerosol medicinali. |
| US7074388B2 (en) * | 1998-12-10 | 2006-07-11 | Kos Life Science, Inc. | Water stabilized medicinal aerosol formulation |
| US6261539B1 (en) * | 1998-12-10 | 2001-07-17 | Akwete Adjei | Medicinal aerosol formulation |
| US20030008369A1 (en) * | 1999-03-03 | 2003-01-09 | Board Of Regents, The University Of Texas System | Genetic and epigenetic manipulation of ABC transporters and ecto-phosphatases |
| GB0002798D0 (en) | 2000-02-09 | 2000-03-29 | Glaxo Group Ltd | Actuator nozzle for metered dose inhaler |
| EP1241113A1 (en) | 2001-03-12 | 2002-09-18 | CHIESI FARMACEUTICI S.p.A. | Inhaler with means for improving chemical stability of medicinal aerosol solution contained therein |
| EP1414508B1 (en) | 2001-06-26 | 2011-04-20 | Norton Healthcare Limited | An improved aerosol actuator |
-
2004
- 2004-03-19 SI SI200430720T patent/SI1608336T1/sl unknown
- 2004-03-19 UA UAA200509733A patent/UA89751C2/ru unknown
- 2004-03-19 WO PCT/US2004/008375 patent/WO2004084858A2/en not_active Ceased
- 2004-03-19 NZ NZ542957A patent/NZ542957A/en not_active IP Right Cessation
- 2004-03-19 PL PL04757846T patent/PL1608336T3/pl unknown
- 2004-03-19 EA EA200501363A patent/EA009087B1/ru unknown
- 2004-03-19 DE DE602004012718T patent/DE602004012718T2/de not_active Expired - Lifetime
- 2004-03-19 KR KR1020057017414A patent/KR101113003B1/ko not_active Expired - Fee Related
- 2004-03-19 BR BRPI0408547-7A patent/BRPI0408547A/pt not_active Application Discontinuation
- 2004-03-19 US US10/804,710 patent/US7914770B2/en active Active
- 2004-03-19 JP JP2006507344A patent/JP4708332B2/ja not_active Expired - Lifetime
- 2004-03-19 ES ES04757846T patent/ES2304616T3/es not_active Expired - Lifetime
- 2004-03-19 MX MXPA05009920A patent/MXPA05009920A/es active IP Right Grant
- 2004-03-19 AU AU2004224367A patent/AU2004224367B2/en not_active Ceased
- 2004-03-19 EP EP04757846A patent/EP1608336B1/en not_active Expired - Lifetime
- 2004-03-19 CA CA2519523A patent/CA2519523C/en not_active Expired - Fee Related
- 2004-03-19 AT AT04757846T patent/ATE390125T1/de active
- 2004-03-19 DK DK04757846T patent/DK1608336T3/da active
- 2004-03-19 CN CNA200480007545XA patent/CN1761455A/zh active Pending
- 2004-03-19 PT PT04757846T patent/PT1608336E/pt unknown
- 2004-03-19 HR HRP20050822AA patent/HRP20050822B1/hr not_active IP Right Cessation
- 2004-03-19 RS YU20050705A patent/RS51663B/sr unknown
- 2004-03-19 ME MEP-2008-626A patent/ME00420B/me unknown
-
2005
- 2005-08-12 ZA ZA200506463A patent/ZA200506463B/en unknown
- 2005-09-20 EC EC2005006029A patent/ECSP056029A/es unknown
- 2005-10-19 NO NO20054839A patent/NO336457B1/no not_active IP Right Cessation
- 2005-10-19 CO CO05106413A patent/CO5640070A2/es not_active Application Discontinuation
-
2008
- 2008-06-11 CY CY20081100626T patent/CY1108137T1/el unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006520797A5 (enExample) | ||
| CN116075306B (zh) | 用于治疗冠状病毒感染的化合物 | |
| JP2009537246A5 (enExample) | ||
| NZ600790A (en) | Combination therapy for copd | |
| JP2013542940A5 (enExample) | ||
| AR066313A2 (es) | Una formulacion de liberacion controlada de galantamina, una forma farmaceutica de dosificacion, un proceso para la preparacion de dicha formulacion, y el uso de dicha formulacion para la manufactura de un medicamento | |
| JP2016040316A5 (enExample) | ||
| JP2012517987A5 (ja) | 吸入用の医薬組成物のｆｐｄ特性を設定する方法 | |
| HRP20130835T1 (hr) | Farmaceutske formulacije otopine za davanje kao stlaäśeni inhalat u inhalatoru | |
| HRP20140550T1 (hr) | Aerosolna formulacija za copd | |
| HRP20170014T1 (hr) | Farmaceutski pripravak za inhalaciju | |
| ES3029560T3 (en) | 5-amino-2,3-dihydro-1,4-phthalazinedione as glucocorticoid-sparing agent | |
| JP2014530231A5 (enExample) | ||
| JP2009521473A5 (enExample) | ||
| WO2002024203A3 (en) | Controlled release formulations for oral administration | |
| JP2009517411A5 (enExample) | ||
| JP2004529108A5 (enExample) | ||
| JP2008533022A5 (enExample) | ||
| US20240075029A1 (en) | Luminol for the prophylaxis and the treatment of sequelae of a sars-cov-2 infection | |
| KR20180119597A (ko) | 염증 상태의 급성 악화의 치료를 위한 투약법 | |
| PL211574B1 (pl) | Kompozycja farmaceutyczna zawierająca mieszankę pierwszego aktywnego składnika wybranego grupy składającej się z roflumilastu jego farmaceutycznie akceptowanych soli i N-tlenków;i drugiego aktywnego składnika wybranego z grupy składającej się z cetyryzyny i jej farmaceutycznie akceptowanych soli, zastosowanie wspomnianej kompozycji, sposób wytwarzania wspomnianej kompozycji, produkt farmaceutyczny zawierający preparaty wspomnianych składników aktywnych oraz zastosowanie wspomnianego produktu farmaceutycznego | |
| WO2006053089A3 (en) | Methods and formulations for making pharmaceutical compositions containing bupropion | |
| HRP20050579A2 (hr) | Nove sinergistične kombinacije koje sadrže roflumilast i formoterol | |
| CN101721415A (zh) | 一种抗感冒的药用组合物及其制备方法 | |
| CN101474191B (zh) | 一种治疗哮喘和慢性阻塞性肺病的药物组合物 |