JP2006520610A5 - - Google Patents
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- Publication number
- JP2006520610A5 JP2006520610A5 JP2006509121A JP2006509121A JP2006520610A5 JP 2006520610 A5 JP2006520610 A5 JP 2006520610A5 JP 2006509121 A JP2006509121 A JP 2006509121A JP 2006509121 A JP2006509121 A JP 2006509121A JP 2006520610 A5 JP2006520610 A5 JP 2006520610A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45182003P | 2003-03-04 | 2003-03-04 | |
| PCT/US2004/006571 WO2004078937A2 (en) | 2003-03-04 | 2004-03-04 | Vectors used to create hybrid constant regions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006520610A JP2006520610A (ja) | 2006-09-14 |
| JP2006520610A5 true JP2006520610A5 (cg-RX-API-DMAC7.html) | 2007-01-11 |
Family
ID=32962642
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509121A Pending JP2006520610A (ja) | 2003-03-04 | 2004-03-04 | ハイブリッド不変領域を産生するのに用いるベクター |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20070009957A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1606387A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2006520610A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2004217433A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2517519A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2004078937A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7408041B2 (en) | 2000-12-08 | 2008-08-05 | Alexion Pharmaceuticals, Inc. | Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof |
| AU2002246632B2 (en) | 2000-12-08 | 2007-04-05 | Alexion Pharmaceuticals, Inc. | Chronic lymphocytic leukemia cell line and its use for producing an antibody |
| US20060057651A1 (en) | 2000-12-08 | 2006-03-16 | Bowdish Katherine S | Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof |
| US9249229B2 (en) | 2000-12-08 | 2016-02-02 | Alexion Pharmaceuticals, Inc. | Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof |
| ES2255616T3 (es) | 2001-04-27 | 2006-07-01 | Alexion Pharmaceuticals, Inc. | Vectores fagemidos. |
| EP2463305B1 (en) | 2006-01-12 | 2016-05-11 | Alexion Pharmaceuticals, Inc. | Antibodies to OX-2/CD200 and uses thereof |
| CA2694121C (en) | 2007-07-25 | 2016-06-07 | Alexion Pharmaceuticals, Inc. | Methods and compositions for treating autoimmune disease |
| US20110059471A1 (en) * | 2008-03-14 | 2011-03-10 | Medinet Co., Ltd. | Antibody having an immune-enhancement function |
| PL2346994T3 (pl) | 2008-09-30 | 2022-04-19 | Ablexis, Llc | Myszy knock-in do wytwarzania chimerycznych przeciwciał |
| US20130045492A1 (en) | 2010-02-08 | 2013-02-21 | Regeneron Pharmaceuticals, Inc. | Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain |
| US9796788B2 (en) | 2010-02-08 | 2017-10-24 | Regeneron Pharmaceuticals, Inc. | Mice expressing a limited immunoglobulin light chain repertoire |
| SG183149A1 (en) | 2010-02-08 | 2012-09-27 | Regeneron Pharma | Common light chain mouse |
| PL3248462T3 (pl) | 2010-03-31 | 2024-07-08 | Ablexis, Llc | Modyfikacja myszy metodami inżynierii genetycznej w celu wytworzenia przeciwciał chimerycznych |
| ES2872081T3 (es) | 2011-08-05 | 2021-11-02 | Regeneron Pharma | Ratones con cadena ligera universal humanizada |
| AU2015230938C1 (en) | 2014-03-21 | 2021-10-14 | Regeneron Pharmaceuticals, Inc. | Non-human animals that make single domain binding proteins |
| CN107438622A (zh) | 2015-03-19 | 2017-12-05 | 瑞泽恩制药公司 | 选择结合抗原的轻链可变区的非人动物 |
| WO2019067499A1 (en) | 2017-09-27 | 2019-04-04 | Alexion Pharmaceuticals, Inc. | BIOMARKER SIGNATURE FOR PREDICTING A TUMOR RESPONSE TO ANTI-CD200 THERAPY |
| JP7627413B2 (ja) * | 2020-08-21 | 2025-02-06 | ファチアブジェン インコーポレイテッド | ガンマ定常領域（Ｃγ１）とイプシロン定常領域（Ｃε２－４）とが融合された重鎖及び軽鎖の定常領域からなる抗体断片及びその用途 |
| CN117430696A (zh) * | 2022-07-22 | 2024-01-23 | 北京智仁美博生物科技有限公司 | 用于表达Fab片段库的重组系统 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5618920A (en) * | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| US7119248B1 (en) * | 1994-04-12 | 2006-10-10 | Miltenyi Biotec Gmbh | Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof |
| US6258529B1 (en) * | 1994-12-01 | 2001-07-10 | Oravax, Inc. | PCR amplification of rearranged genomic variable regions of immunoglobulin genes |
| BR9708910A (pt) * | 1996-05-04 | 1999-08-03 | Zeneca Ltd | Anticorpo conjugado sequência de polinucleotídeos vetor célula hospedeira hibridoma composição farmacêutica processos para fabricar um anticorpo ou um conjugado e para tratar um humano ou animal em necessidade deste tratamento |
| DE60131456T2 (de) * | 2000-11-30 | 2008-07-10 | Medarex, Inc., Milpitas | Transchromosomale transgen-nagetiere zur herstellung von humanen antikörpern |
| WO2002046477A2 (en) * | 2000-12-07 | 2002-06-13 | Chiron Corporation | Endogenous retroviruses up-regulated in prostate cancer |
| ES2255616T3 (es) * | 2001-04-27 | 2006-07-01 | Alexion Pharmaceuticals, Inc. | Vectores fagemidos. |
| WO2003002608A1 (fr) * | 2001-06-28 | 2003-01-09 | Kyowa Hakko Kogyo Co., Ltd. | Anticorps humanise contre le facteur-8 de croissance des fibroblastes et fragment de cet anticorps |
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2004
- 2004-03-04 US US10/547,275 patent/US20070009957A1/en not_active Abandoned
- 2004-03-04 AU AU2004217433A patent/AU2004217433A1/en not_active Abandoned
- 2004-03-04 WO PCT/US2004/006571 patent/WO2004078937A2/en not_active Ceased
- 2004-03-04 EP EP04717390A patent/EP1606387A4/en not_active Withdrawn
- 2004-03-04 JP JP2006509121A patent/JP2006520610A/ja active Pending
- 2004-03-04 CA CA002517519A patent/CA2517519A1/en not_active Abandoned