JP2006514665A - 慢性心不全および／または上昇したコレステロールレベルを処置するための方法 - Google Patents

慢性心不全および／または上昇したコレステロールレベルを処置するための方法 Download PDF

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Publication number
JP2006514665A
JP2006514665A JP2004568567A JP2004568567A JP2006514665A JP 2006514665 A JP2006514665 A JP 2006514665A JP 2004568567 A JP2004568567 A JP 2004568567A JP 2004568567 A JP2004568567 A JP 2004568567A JP 2006514665 A JP2006514665 A JP 2006514665A
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JP
Japan
Prior art keywords
acid
tetraiodosilopionic
administered
triiodocylopropionic
triprop
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JP2004568567A
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Japanese (ja)
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JP2006514665A5 (https=
Inventor
ユージーン モーキン，
Original Assignee
ザ アリゾナ ボード オブ リージェンツ オン ビハーフ オブ ザ ユニバーシティ オブ アリゾナ
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Application filed by ザ アリゾナ ボード オブ リージェンツ オン ビハーフ オブ ザ ユニバーシティ オブ アリゾナ filed Critical ザ アリゾナ ボード オブ リージェンツ オン ビハーフ オブ ザ ユニバーシティ オブ アリゾナ
Publication of JP2006514665A publication Critical patent/JP2006514665A/ja
Publication of JP2006514665A5 publication Critical patent/JP2006514665A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2004568567A 2003-02-18 2003-10-20 慢性心不全および／または上昇したコレステロールレベルを処置するための方法 Pending JP2006514665A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/368,755 US6716877B2 (en) 2001-01-31 2003-02-18 Method to treat chronic heart failure and/or elevated cholesterol levels
PCT/US2003/033333 WO2004073694A1 (en) 2003-02-18 2003-10-20 Method to treat chronic heart failure and/or elevated cholesterol levels

Publications (2)

Publication Number Publication Date
JP2006514665A true JP2006514665A (ja) 2006-05-11
JP2006514665A5 JP2006514665A5 (https=) 2006-06-29

Family

ID=32907645

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004568567A Pending JP2006514665A (ja) 2003-02-18 2003-10-20 慢性心不全および／または上昇したコレステロールレベルを処置するための方法

Country Status (7)

Country Link
US (1) US6716877B2 (https=)
EP (1) EP1594480A4 (https=)
JP (1) JP2006514665A (https=)
AU (1) AU2003286546B2 (https=)
CA (1) CA2516450A1 (https=)
MX (1) MXPA05008596A (https=)
WO (1) WO2004073694A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017507929A (ja) * 2014-02-10 2017-03-23 フレッド ハッチンソン キャンサー リサーチ センター 心臓発作及び虚血損傷のハロゲン治療

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI107018B (fi) * 2000-04-06 2001-05-31 Ipsat Therapies Oy Dermatologinen käyttö ja valmiste
US7504435B2 (en) * 2001-01-31 2009-03-17 The Arizona Board Of Regents On Behalf Of The University Of Arizona Method for stimulating weight loss and/or for lowering triglycerides in patients
WO2006128058A2 (en) 2005-05-26 2006-11-30 Metabasis Therapeutics, Inc. Thyromimetics for the treatment of fatty liver diseases
CN1882327A (zh) * 2003-11-19 2006-12-20 症变治疗公司 含磷的新的拟甲状腺素药
WO2006128056A2 (en) * 2005-05-26 2006-11-30 Metabasis Therapeutics, Inc. Novel phosphinic acid-containing thyromimetics
EP2199271A4 (en) * 2007-08-31 2011-05-18 Mitsubishi Gas Chemical Co METHOD FOR PRODUCING PHENOL DERIVATIVES SUBSTITUTED WITH IODINE AT THE ORTHO POSITION
US20090131380A1 (en) * 2007-11-16 2009-05-21 Pekka Heino Novel pharmaceutical composition for topical treatment of skin psoriasis and the treatment method thereof
CA3044059A1 (en) 2016-11-21 2018-05-24 Viking Therapeutics, Inc. Method of treating glycogen storage disease
US11707472B2 (en) 2017-06-05 2023-07-25 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis
US11458094B2 (en) * 2018-01-31 2022-10-04 Regents Of The University Of Minnesota Compositions and methods for treating pulmonary edema or lung inflammation
ES3053674T3 (en) 2018-03-22 2026-01-23 Viking Therapeutics Inc Crystalline forms and methods of producing crystalline forms of a compound
WO2020117962A1 (en) 2018-12-05 2020-06-11 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis and inflammation
CA3177377A1 (en) 2020-03-27 2021-09-30 Regents Of The University Of Minnesota Compositions and methods for treating pulmonary edema or lung inflammation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3109023A (en) 1958-06-10 1963-10-29 Hooker Chemical Corp 2, 3, 6-trichloro-5-nitrobenzoic acid and salts thereof
US5158978A (en) * 1990-02-05 1992-10-27 British Technology Group (U.S.A.) Thyroid hormone treatment of acute cardiovascular compromise
US5284971A (en) 1992-07-16 1994-02-08 Syntex (U.S.A.) Inc. 4-(3-cyclohexyl-4-hydroxy or-methoxy phenylsulfonyl) 3,5 dibromo phenyl acetic thyromimetic cholesterol-lowering agents
US6221911B1 (en) * 1995-06-07 2001-04-24 Karo Bio Ab Uses for thyroid hormone compounds or thyroid hormone-like compounds
US5883294A (en) 1997-06-18 1999-03-16 The Regeants Of The University Of California Selective thyroid hormone analogs
US6534676B2 (en) * 2001-01-31 2003-03-18 The Arizona Board Of Regents On Behalf Of The University Of Arizona Method to treat chronic heart failure and/or elevated cholesterol levels using 3,5-diiodothyropropionic acid and method to prepare same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017507929A (ja) * 2014-02-10 2017-03-23 フレッド ハッチンソン キャンサー リサーチ センター 心臓発作及び虚血損傷のハロゲン治療
JP2019194265A (ja) * 2014-02-10 2019-11-07 フレッド ハッチンソン キャンサー リサーチ センター 心臓発作及び虚血損傷のハロゲン治療

Also Published As

Publication number Publication date
WO2004073694A1 (en) 2004-09-02
EP1594480A1 (en) 2005-11-16
US6716877B2 (en) 2004-04-06
CA2516450A1 (en) 2004-09-02
EP1594480A4 (en) 2007-08-29
AU2003286546A1 (en) 2004-09-09
US20030147815A1 (en) 2003-08-07
MXPA05008596A (es) 2006-02-28
AU2003286546B2 (en) 2009-06-11

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