JP2006514004A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006514004A5 JP2006514004A5 JP2004550229A JP2004550229A JP2006514004A5 JP 2006514004 A5 JP2006514004 A5 JP 2006514004A5 JP 2004550229 A JP2004550229 A JP 2004550229A JP 2004550229 A JP2004550229 A JP 2004550229A JP 2006514004 A5 JP2006514004 A5 JP 2006514004A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- composition
- cells
- cell
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42309002P | 2002-10-30 | 2002-10-30 | |
| US60/423,090 | 2002-10-30 | ||
| PCT/US2003/034429 WO2004042009A2 (en) | 2002-10-30 | 2003-10-29 | Inhibition of il-17 production |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010210980A Division JP5705483B2 (ja) | 2002-10-30 | 2010-09-21 | Il−17産生の阻害 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006514004A JP2006514004A (ja) | 2006-04-27 |
| JP2006514004A5 true JP2006514004A5 (https=) | 2006-10-19 |
| JP5477998B2 JP5477998B2 (ja) | 2014-04-23 |
Family
ID=32312602
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004550229A Expired - Lifetime JP5477998B2 (ja) | 2002-10-30 | 2003-10-29 | Il−17産生の阻害 |
| JP2010210980A Expired - Lifetime JP5705483B2 (ja) | 2002-10-30 | 2010-09-21 | Il−17産生の阻害 |
| JP2013123690A Expired - Lifetime JP5870067B2 (ja) | 2002-10-30 | 2013-06-12 | Il−17産生の阻害 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010210980A Expired - Lifetime JP5705483B2 (ja) | 2002-10-30 | 2010-09-21 | Il−17産生の阻害 |
| JP2013123690A Expired - Lifetime JP5870067B2 (ja) | 2002-10-30 | 2013-06-12 | Il−17産生の阻害 |
Country Status (17)
| Country | Link |
|---|---|
| US (6) | US7510709B2 (https=) |
| EP (2) | EP1576011B1 (https=) |
| JP (3) | JP5477998B2 (https=) |
| KR (2) | KR101076931B1 (https=) |
| CN (2) | CN101824088B (https=) |
| AT (1) | ATE439166T1 (https=) |
| AU (1) | AU2003287257C1 (https=) |
| CA (1) | CA2501786C (https=) |
| DE (1) | DE60328823D1 (https=) |
| DK (1) | DK1576011T3 (https=) |
| ES (1) | ES2329673T3 (https=) |
| IL (1) | IL167845A (https=) |
| MX (1) | MXPA05004512A (https=) |
| NZ (1) | NZ539271A (https=) |
| PT (1) | PT1576011E (https=) |
| WO (1) | WO2004042009A2 (https=) |
| ZA (1) | ZA200503013B (https=) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6706264B1 (en) * | 1994-03-14 | 2004-03-16 | Genetics Institute, Llc | Use of IL-12 antagonists in the treatment of conditions promoted by an increase in levels of IFN-y |
| US20020137890A1 (en) * | 1997-03-31 | 2002-09-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| AU740405B2 (en) | 1998-05-15 | 2001-11-01 | Genentech Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
| US7771719B1 (en) * | 2000-01-11 | 2010-08-10 | Genentech, Inc. | Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E |
| US20040043397A1 (en) * | 2000-01-11 | 2004-03-04 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
| US20030203451A1 (en) * | 2000-08-24 | 2003-10-30 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
| US7718397B2 (en) | 2000-03-21 | 2010-05-18 | Genentech, Inc. | Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof |
| US7422743B2 (en) | 2000-05-10 | 2008-09-09 | Schering Corporation | Mammalian receptor protein DCRS5;methods of treatment |
| US20030096969A1 (en) | 2000-06-02 | 2003-05-22 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US20070160576A1 (en) | 2001-06-05 | 2007-07-12 | Genentech, Inc. | IL-17A/F heterologous polypeptides and therapeutic uses thereof |
| US20040219150A1 (en) * | 2003-02-06 | 2004-11-04 | Cua Daniel J. | Uses of mammalian cytokine; related reagents |
| CN101052726A (zh) | 2003-05-09 | 2007-10-10 | 森托科尔公司 | IL-23p40特异性免疫球蛋白衍生蛋白、组合物、方法和用途 |
| EP2784084B2 (en) | 2003-07-08 | 2023-10-04 | Novartis Pharma AG | Antagonist antibodies to IL-17A/F heterologous polypeptides |
| HUE026260T2 (en) * | 2003-11-21 | 2016-06-28 | Ucb Biopharma Sprl | A method for treating multiple sclerosis by inhibiting IL-17 activity |
| US20050226878A1 (en) * | 2003-12-02 | 2005-10-13 | 3M Innovative Properties Company | Therapeutic combinations and methods including IRM compounds |
| US8940755B2 (en) * | 2003-12-02 | 2015-01-27 | 3M Innovative Properties Company | Therapeutic combinations and methods including IRM compounds |
| CN1942201B (zh) * | 2004-02-17 | 2012-06-20 | 先灵公司 | 调节il-23活性的方法;相关试剂 |
| US20050287593A1 (en) | 2004-05-03 | 2005-12-29 | Schering Corporation | Use of cytokine expression to predict skin inflammation; methods of treatment |
| BRPI0510617A (pt) * | 2004-05-03 | 2007-10-30 | Schering Corp | uso de expressão de il-17 para prever inflamação de pele; processos de tratamento |
| AR051444A1 (es) | 2004-09-24 | 2007-01-17 | Centocor Inc | Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos |
| US7820168B2 (en) * | 2004-12-20 | 2010-10-26 | Schering Corporation | Treatment of diabetes using antibodies to IL-23, IL-23 receptor and IL-17 |
| CA2596706A1 (en) * | 2005-01-04 | 2006-07-13 | University Of Rochester | Blockade of elr+cxc chemokines as a treatment for inflammatory and autoimmune disease |
| CN103145842A (zh) * | 2005-06-30 | 2013-06-12 | Abbvie公司 | Il-12/p40结合蛋白 |
| SI2452694T1 (sl) | 2005-06-30 | 2019-05-31 | Janssen Biotech, Inc. | Protitelesa proti-IL-23, sestavki in postopki uporabe |
| PT1931710T (pt) | 2005-08-31 | 2017-03-28 | Merck Sharp & Dohme | Anticorpos anti-il-23 manipulados |
| US20080199460A1 (en) * | 2005-09-01 | 2008-08-21 | Schering Corporation | Use of IL-23 and IL-17 antagonists to treat autoimmune ocular inflammatory disease |
| BRPI0619118A2 (pt) | 2005-12-02 | 2011-09-13 | Genentech Inc | composições e métodos para o tratamento de doenças e desordens associadas com a sinalização de citocina |
| HUE034269T2 (en) | 2005-12-29 | 2018-02-28 | Janssen Biotech Inc | Human anti-IL-23 antibodies, preparations, methods and applications |
| US7910703B2 (en) | 2006-03-10 | 2011-03-22 | Zymogenetics, Inc. | Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use |
| JP2010502224A (ja) * | 2006-09-08 | 2010-01-28 | アボット・ラボラトリーズ | インターロイキン13結合タンパク質 |
| US8414897B1 (en) * | 2006-10-02 | 2013-04-09 | The Uab Research Foundation | Pathway for Th-17 cell development and methods utilizing same |
| TWI426918B (zh) * | 2007-02-12 | 2014-02-21 | Merck Sharp & Dohme | Il-23拮抗劑於治療感染之用途 |
| ES2708988T3 (es) | 2007-02-23 | 2019-04-12 | Merck Sharp & Dohme | Anticuerpos anti-IL-23p19 obtenidos por ingeniería genética |
| NZ579251A (en) * | 2007-02-28 | 2012-06-29 | Schering Corp | Engineered anti-il-23r antibodies |
| US20100331545A1 (en) | 2007-10-24 | 2010-12-30 | Nippon Chemiphar Co., Ltd. | Regulator for signaling toll-like receptor, which comprises cathepsin inhibitor as active ingredient |
| CA2717987C (en) * | 2008-04-29 | 2018-11-13 | Micromet Ag | Inhibitors of gm-csf and il-17 for therapy |
| RU2474588C2 (ru) | 2008-05-05 | 2013-02-10 | Новиммун Са | Перекрестно-реактивные антитела анти-il-17a/il-17f и способы их применения |
| SG2014006860A (en) * | 2008-11-12 | 2014-05-29 | Merck Sharp & Dohme | ßGI-IGG INTRON FOR ENHANCED ANTI-IGF1 R EXPRESSION |
| US20100233270A1 (en) | 2009-01-08 | 2010-09-16 | Northwestern University | Delivery of Oligonucleotide-Functionalized Nanoparticles |
| CN102458437B (zh) | 2009-05-05 | 2015-06-10 | 诺维莫尼公司 | 抗il-17f抗体及其使用方法 |
| JP2011032170A (ja) * | 2009-07-29 | 2011-02-17 | Morinaga Milk Ind Co Ltd | ヒト細胞il−17産生抑制剤 |
| EP2480251B1 (en) | 2009-09-21 | 2025-12-03 | Peptinov | Carrier conjugates of il-23-peptides and their induced antibodies |
| JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
| WO2011062628A1 (en) * | 2009-11-20 | 2011-05-26 | New York University | Methods and compositions for modulation of t cells via the kynurenine pathway |
| GB201013975D0 (en) | 2010-08-20 | 2010-10-06 | Imp Innovations Ltd | Method of treating desease |
| CN102010903A (zh) * | 2010-08-26 | 2011-04-13 | 中国医学科学院肿瘤研究所 | Il-23在肝癌早期病变诊断中的应用 |
| MX2019000046A (es) | 2010-11-04 | 2023-10-05 | Boehringer Ingelheim Int | Anticuerpos anti-il-23. |
| EP2809660B1 (en) | 2012-02-02 | 2016-01-20 | Ensemble Therapeutics Corporation | Macrocyclic compounds for modulating il-17 |
| PL3326649T3 (pl) | 2012-05-03 | 2022-04-25 | Boehringer Ingelheim International Gmbh | Przeciwciała anty-il-23p19 |
| EP3415534A1 (en) | 2013-05-10 | 2018-12-19 | Numab Therapeutics AG | Bispecific constructs and their use in the treatment of various diseases |
| US10745475B2 (en) | 2013-08-30 | 2020-08-18 | Takeda Gmbh | Antibodies neutralizing GM-CSF for use in the treatment of rheumatoid arthritis or as analgesics |
| EP3708679A1 (en) | 2014-07-24 | 2020-09-16 | Boehringer Ingelheim International GmbH | Biomarkers useful in the treatment of il-23a related diseases |
| EA202193002A2 (ru) | 2014-09-03 | 2022-03-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Соединение, нацеленное на ил-23a и фно-альфа, и его применение |
| AR102417A1 (es) | 2014-11-05 | 2017-03-01 | Lilly Co Eli | Anticuerpos biespecíficos anti-tnf- / anti-il-23 |
| AU2016215535B2 (en) | 2015-02-04 | 2021-09-16 | Boehringer Ingelheim International Gmbh | Methods of treating inflammatory diseases |
| EP3452598A4 (en) | 2016-05-06 | 2020-04-29 | Exicure, Inc. | LIPOSOMAL SPHERICAL NUCLEIC ACID (ANS) CONSTRUCTS HAVING ANTISENSE OLIGONUCLEOTIDES (ASO) FOR THE SPECIFIC INACTIVATION OF INTERLEUKIN 17 RECEPTOR RNA |
| IL283192B2 (en) | 2018-11-20 | 2025-10-01 | Janssen Biotech Inc | A safe and effective method for treating psoriasis with a specific anti-IL-23 antibody |
| JP7805788B2 (ja) | 2019-05-23 | 2026-01-26 | ヤンセン バイオテツク,インコーポレーテツド | Il-23及びtnfアルファに対する抗体の併用療法による炎症性腸疾患の治療方法 |
| TW202535466A (zh) | 2019-09-09 | 2025-09-16 | 德商百靈佳殷格翰國際股份有限公司 | 抗-il-23p19抗體調配物 |
| US20230167497A1 (en) * | 2020-04-30 | 2023-06-01 | Xiaohua Xue | Methods of identifying modulators of the il-17 pathway |
| IL298389A (en) | 2020-05-21 | 2023-01-01 | Janssen Biotech Inc | Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha |
| CN112300285B (zh) * | 2020-11-06 | 2022-08-02 | 江苏荃信生物医药股份有限公司 | 一种定量检测血清中抗人白介素17单克隆抗体含量的酶联免疫分析方法 |
| CN116183472B (zh) * | 2023-04-25 | 2023-08-18 | 上海益诺思生物技术股份有限公司 | Cba法检测非人类灵长类动物细胞因子的验证方法 |
| WO2026058045A1 (en) | 2024-09-12 | 2026-03-19 | Takeda Pharmaceutical Company Limited | Alpha4beta7 inhibitor and il-23 inhibitor combination therapy |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001018022A1 (en) | 1999-09-03 | 2001-03-15 | Human Genome Sciences, Inc. | 52 human secreted proteins |
| ZA986596B (en) | 1997-07-25 | 1999-02-08 | Schering Corp | Mammalian cytokine related reagents |
| US6060284A (en) * | 1997-07-25 | 2000-05-09 | Schering Corporation | DNA encoding interleukin-B30 |
| DE69942607D1 (de) * | 1998-04-14 | 2010-09-02 | Chugai Pharmaceutical Co Ltd | Neues cytokinartiges protein |
| US6448081B1 (en) * | 2001-05-07 | 2002-09-10 | Isis Pharmaceuticals, Inc. | Antisense modulation of interleukin 12 p40 subunit expression |
| EP2341144A1 (en) * | 1999-01-11 | 2011-07-06 | Schering Corporation | Interleukin-17 related mammalian cytokines. Polynucleotides encoding them. Uses |
| US6914128B1 (en) * | 1999-03-25 | 2005-07-05 | Abbott Gmbh & Co. Kg | Human antibodies that bind human IL-12 and methods for producing |
| HUP0200575A3 (en) | 1999-03-25 | 2004-11-29 | Abbott Gmbh & Co Kg | Human antibodies that bind human il-12 and methods for producing |
| US20030082734A1 (en) * | 1999-06-01 | 2003-05-01 | Dowling Lynette M. | Mammalian receptor proteins; related reagents and methods |
| AU780163B2 (en) | 1999-09-09 | 2005-03-03 | Merck Sharp & Dohme Corp. | Mammalian interleukin-12 P40 and interleukin B30, combinations thereof, antibodies, uses in pharmaceutical compositions |
| AU7445900A (en) * | 1999-09-27 | 2001-04-30 | Chugai Seiyaku Kabushiki Kaisha | Novel hemopoietin receptor protein, nr12 |
| US6756481B2 (en) | 2000-05-10 | 2004-06-29 | Schering Corporation | IL-23 receptor binding compositions |
| US7422743B2 (en) * | 2000-05-10 | 2008-09-09 | Schering Corporation | Mammalian receptor protein DCRS5;methods of treatment |
| US6902734B2 (en) * | 2000-08-07 | 2005-06-07 | Centocor, Inc. | Anti-IL-12 antibodies and compositions thereof |
| JP3899861B2 (ja) * | 2001-07-13 | 2007-03-28 | 株式会社日立製作所 | 光ディスク、情報再生方法及び記録方法 |
| US7282204B2 (en) * | 2003-03-10 | 2007-10-16 | Schering Corporation | Uses of IL-23 agonists and antagonists; related reagents |
| AU2004289303A1 (en) * | 2003-11-10 | 2005-05-26 | Synta Pharmaceuticals, Corp. | Fused heterocyclic compounds |
| AU2004289304A1 (en) | 2003-11-10 | 2005-05-26 | Synta Pharmaceuticals, Corp. | Pyridine compounds |
| EP1689403A4 (en) | 2003-11-10 | 2007-09-05 | Synta Pharmaceuticals Corp | HETEROARYL-hydrazone compounds |
| CN1942201B (zh) * | 2004-02-17 | 2012-06-20 | 先灵公司 | 调节il-23活性的方法;相关试剂 |
| BRPI0510617A (pt) | 2004-05-03 | 2007-10-30 | Schering Corp | uso de expressão de il-17 para prever inflamação de pele; processos de tratamento |
| US20050287593A1 (en) * | 2004-05-03 | 2005-12-29 | Schering Corporation | Use of cytokine expression to predict skin inflammation; methods of treatment |
| AR051444A1 (es) * | 2004-09-24 | 2007-01-17 | Centocor Inc | Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos |
| KR101004362B1 (ko) | 2010-03-19 | 2010-12-28 | 가톨릭대학교 산학협력단 | 자가 면역 질환 예방 및 치료용 TNF-α와 TWEAK 이중 길항제 |
-
2003
- 2003-10-29 WO PCT/US2003/034429 patent/WO2004042009A2/en not_active Ceased
- 2003-10-29 JP JP2004550229A patent/JP5477998B2/ja not_active Expired - Lifetime
- 2003-10-29 AT AT03781490T patent/ATE439166T1/de active
- 2003-10-29 MX MXPA05004512A patent/MXPA05004512A/es active IP Right Grant
- 2003-10-29 AU AU2003287257A patent/AU2003287257C1/en not_active Expired
- 2003-10-29 CA CA2501786A patent/CA2501786C/en not_active Expired - Lifetime
- 2003-10-29 US US10/697,599 patent/US7510709B2/en not_active Expired - Lifetime
- 2003-10-29 KR KR1020057007502A patent/KR101076931B1/ko not_active Expired - Lifetime
- 2003-10-29 PT PT03781490T patent/PT1576011E/pt unknown
- 2003-10-29 CN CN2010101439342A patent/CN101824088B/zh not_active Expired - Lifetime
- 2003-10-29 DE DE60328823T patent/DE60328823D1/de not_active Expired - Lifetime
- 2003-10-29 CN CN2003801027073A patent/CN1711282B/zh not_active Expired - Lifetime
- 2003-10-29 DK DK03781490T patent/DK1576011T3/da active
- 2003-10-29 EP EP03781490A patent/EP1576011B1/en not_active Revoked
- 2003-10-29 NZ NZ539271A patent/NZ539271A/en not_active IP Right Cessation
- 2003-10-29 ES ES03781490T patent/ES2329673T3/es not_active Expired - Lifetime
- 2003-10-29 KR KR1020117003939A patent/KR101053412B1/ko not_active Expired - Lifetime
- 2003-10-29 EP EP20090007964 patent/EP2108660A1/en not_active Ceased
-
2005
- 2005-04-04 IL IL167845A patent/IL167845A/en unknown
- 2005-04-14 ZA ZA200503013A patent/ZA200503013B/en unknown
-
2009
- 2009-01-07 US US12/350,125 patent/US8287869B2/en not_active Expired - Lifetime
- 2009-01-07 US US12/350,089 patent/US20100266582A1/en not_active Abandoned
-
2010
- 2010-09-21 JP JP2010210980A patent/JP5705483B2/ja not_active Expired - Lifetime
-
2012
- 2012-10-11 US US13/649,810 patent/US20130309194A1/en not_active Abandoned
-
2013
- 2013-06-12 JP JP2013123690A patent/JP5870067B2/ja not_active Expired - Lifetime
-
2016
- 2016-03-10 US US15/066,568 patent/US20160326229A1/en not_active Abandoned
-
2018
- 2018-04-19 US US15/957,879 patent/US20190092829A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5477998B2 (ja) | Il−17産生の阻害 | |
| JP2006514004A5 (https=) | ||
| US7560530B1 (en) | IL-33 receptor | |
| US20090142806A1 (en) | Interleukin-17f antibodies and other il-17f signaling antagonists and uses therefor | |
| EP2171044A1 (en) | Th-17 cells | |
| HK1135415A (en) | Inhibition of il-17 production |