JP2006514004A5 - - Google Patents

Download PDF

Info

Publication number
JP2006514004A5
JP2006514004A5 JP2004550229A JP2004550229A JP2006514004A5 JP 2006514004 A5 JP2006514004 A5 JP 2006514004A5 JP 2004550229 A JP2004550229 A JP 2004550229A JP 2004550229 A JP2004550229 A JP 2004550229A JP 2006514004 A5 JP2006514004 A5 JP 2006514004A5
Authority
JP
Japan
Prior art keywords
antibody
composition
cells
cell
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2004550229A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006514004A (ja
JP5477998B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/034429 external-priority patent/WO2004042009A2/en
Publication of JP2006514004A publication Critical patent/JP2006514004A/ja
Publication of JP2006514004A5 publication Critical patent/JP2006514004A5/ja
Application granted granted Critical
Publication of JP5477998B2 publication Critical patent/JP5477998B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2004550229A 2002-10-30 2003-10-29 Il−17産生の阻害 Expired - Lifetime JP5477998B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42309002P 2002-10-30 2002-10-30
US60/423,090 2002-10-30
PCT/US2003/034429 WO2004042009A2 (en) 2002-10-30 2003-10-29 Inhibition of il-17 production

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010210980A Division JP5705483B2 (ja) 2002-10-30 2010-09-21 Il−17産生の阻害

Publications (3)

Publication Number Publication Date
JP2006514004A JP2006514004A (ja) 2006-04-27
JP2006514004A5 true JP2006514004A5 (https=) 2006-10-19
JP5477998B2 JP5477998B2 (ja) 2014-04-23

Family

ID=32312602

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2004550229A Expired - Lifetime JP5477998B2 (ja) 2002-10-30 2003-10-29 Il−17産生の阻害
JP2010210980A Expired - Lifetime JP5705483B2 (ja) 2002-10-30 2010-09-21 Il−17産生の阻害
JP2013123690A Expired - Lifetime JP5870067B2 (ja) 2002-10-30 2013-06-12 Il−17産生の阻害

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2010210980A Expired - Lifetime JP5705483B2 (ja) 2002-10-30 2010-09-21 Il−17産生の阻害
JP2013123690A Expired - Lifetime JP5870067B2 (ja) 2002-10-30 2013-06-12 Il−17産生の阻害

Country Status (17)

Country Link
US (6) US7510709B2 (https=)
EP (2) EP1576011B1 (https=)
JP (3) JP5477998B2 (https=)
KR (2) KR101076931B1 (https=)
CN (2) CN101824088B (https=)
AT (1) ATE439166T1 (https=)
AU (1) AU2003287257C1 (https=)
CA (1) CA2501786C (https=)
DE (1) DE60328823D1 (https=)
DK (1) DK1576011T3 (https=)
ES (1) ES2329673T3 (https=)
IL (1) IL167845A (https=)
MX (1) MXPA05004512A (https=)
NZ (1) NZ539271A (https=)
PT (1) PT1576011E (https=)
WO (1) WO2004042009A2 (https=)
ZA (1) ZA200503013B (https=)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6830751B1 (en) * 1994-03-14 2004-12-14 Genetics Institute, Llc Use of IL-12 antagonists in the treatment of rheumatoid arthritis
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7771719B1 (en) * 2000-01-11 2010-08-10 Genentech, Inc. Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E
NZ508878A (en) 1998-05-15 2003-08-29 Genentech Inc IL-17B and IL-17Cactive variants of IL-17 which stimulates epithelial, endothelial and fibroblastic cells
US20040043397A1 (en) * 2000-01-11 2004-03-04 Genentech, Inc. IL-17 homologous polypeptides and therapeutic uses thereof
US7718397B2 (en) 2000-03-21 2010-05-18 Genentech, Inc. Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof
US20030203451A1 (en) * 2000-08-24 2003-10-30 Genentech, Inc. IL-17 homologous polypeptides and therapeutic uses thereof
US7422743B2 (en) * 2000-05-10 2008-09-09 Schering Corporation Mammalian receptor protein DCRS5;methods of treatment
US20030096969A1 (en) 2000-06-02 2003-05-22 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20070160576A1 (en) 2001-06-05 2007-07-12 Genentech, Inc. IL-17A/F heterologous polypeptides and therapeutic uses thereof
US20040219150A1 (en) * 2003-02-06 2004-11-04 Cua Daniel J. Uses of mammalian cytokine; related reagents
EP1623011B1 (en) 2003-05-09 2013-01-02 Janssen Biotech, Inc. Il-23p40 specific immunoglobulin derived proteins, compositions, methods and uses
PL2784084T5 (pl) 2003-07-08 2024-12-02 Novartis Pharma Ag Przeciwciała antagonistyczne heterologicznych polipeptydów il-17a/f
US20070269428A1 (en) * 2003-11-21 2007-11-22 Celltech R&D Limited Method for the Treatment of Multiple Sclerosis by Inhibiting Il-17 Activity
US8940755B2 (en) * 2003-12-02 2015-01-27 3M Innovative Properties Company Therapeutic combinations and methods including IRM compounds
US20050226878A1 (en) * 2003-12-02 2005-10-13 3M Innovative Properties Company Therapeutic combinations and methods including IRM compounds
AU2005215527B2 (en) * 2004-02-17 2011-04-07 Merck Sharp & Dohme Corp. Methods of modulating IL-23 activity; related reagents
CN1993480A (zh) * 2004-05-03 2007-07-04 先灵公司 Il-17表达预测皮肤炎症的用途;治疗方法
US20050287593A1 (en) 2004-05-03 2005-12-29 Schering Corporation Use of cytokine expression to predict skin inflammation; methods of treatment
AR051444A1 (es) 2004-09-24 2007-01-17 Centocor Inc Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos
EP2292758A3 (en) * 2004-12-20 2013-12-25 Merck Sharp & Dohme Corp. Uses of mammalian cytokine; related reagents
WO2006074179A2 (en) * 2005-01-04 2006-07-13 University Of Rochester Blockade of elr+cxc chemokines as a treatment for inflammatory and autoimmune disease
CN103145839A (zh) * 2005-06-30 2013-06-12 Abbvie公司 Il-12/p40结合蛋白
AU2006265002B2 (en) 2005-06-30 2012-09-20 Centocor, Inc. Anti-IL-23 antibodies, compositions, methods and uses
EP3190125A1 (en) 2005-08-31 2017-07-12 Merck Sharp & Dohme Corp. Engineered anti-il-23 antibodies
PL1933869T3 (pl) 2005-09-01 2010-06-30 Merck Sharp & Dohme Zastosowanie antagonistów IL-23 i IL-17 do leczenia autoimmunologicznej zapalnej choroby oczu
EP1954719A2 (en) * 2005-12-02 2008-08-13 Genentech Inc. Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to il-22 and il-22r
SI1971366T1 (sl) 2005-12-29 2014-10-30 Janssen Biotech, Inc. Humana protitelesa anti-il-23, sestavki, postopki in uporabe
US7910703B2 (en) 2006-03-10 2011-03-22 Zymogenetics, Inc. Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use
CA2914170C (en) 2006-09-08 2018-10-30 Abbvie Bahamas Ltd. Interleukin-13 binding proteins
US8414897B1 (en) * 2006-10-02 2013-04-09 The Uab Research Foundation Pathway for Th-17 cell development and methods utilizing same
TWI426918B (zh) * 2007-02-12 2014-02-21 Merck Sharp & Dohme Il-23拮抗劑於治療感染之用途
AR065420A1 (es) 2007-02-23 2009-06-03 Schering Corp Anticuerpos anti-il-23 p19 de ingenieria
AU2008219684B2 (en) * 2007-02-28 2014-04-17 Merck Sharp & Dohme Corp. Engineered anti-IL-23R antibodies
JPWO2009054454A1 (ja) 2007-10-24 2011-03-03 国立大学法人 東京医科歯科大学 カテプシン阻害剤を有効成分として含有するToll様受容体のシグナル伝達の調整剤
KR101681331B1 (ko) * 2008-04-29 2016-12-01 암젠 리서치 (뮌헨) 게엠베하 치료를 위한 gm-csf 및 il-17의 억제제
SG10201608871XA (en) 2008-05-05 2016-12-29 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
AU2009314111A1 (en) * 2008-11-12 2010-05-20 Merck Sharp & Dohme Corp. BetaGI-IgG intron for enhanced anti-IGF1 R expression
US20100233270A1 (en) 2009-01-08 2010-09-16 Northwestern University Delivery of Oligonucleotide-Functionalized Nanoparticles
CA2759848C (en) * 2009-05-05 2018-12-04 Novimmune S.A. Anti-il-17f antibodies and methods of use thereof
JP2011032170A (ja) * 2009-07-29 2011-02-17 Morinaga Milk Ind Co Ltd ヒト細胞il−17産生抑制剤
US9301997B2 (en) 2009-09-21 2016-04-05 Peptinov Sas Method of vaccination for limiting articular inflammation in rheumatoid arthritis and multiple sclerosis by administering IL-23 peptides
JO3244B1 (ar) 2009-10-26 2018-03-08 Amgen Inc بروتينات ربط مستضادات il – 23 البشرية
US20120252896A1 (en) * 2009-11-20 2012-10-04 Ernst Joel D Methods and compositions for modulation of t-cells via the kynurenine pathway
GB201013975D0 (en) 2010-08-20 2010-10-06 Imp Innovations Ltd Method of treating desease
CN102010903A (zh) * 2010-08-26 2011-04-13 中国医学科学院肿瘤研究所 Il-23在肝癌早期病变诊断中的应用
PE20141162A1 (es) 2010-11-04 2014-09-18 Boehringer Ingelheim Int Anticuerpos anti-il-23
US9284283B2 (en) 2012-02-02 2016-03-15 Ensemble Therapeutics Corporation Macrocyclic compounds for modulating IL-17
EP4039275A1 (en) 2012-05-03 2022-08-10 Boehringer Ingelheim International GmbH Anti-il-23p19 antibodies
EP3415534A1 (en) 2013-05-10 2018-12-19 Numab Therapeutics AG Bispecific constructs and their use in the treatment of various diseases
US10745475B2 (en) 2013-08-30 2020-08-18 Takeda Gmbh Antibodies neutralizing GM-CSF for use in the treatment of rheumatoid arthritis or as analgesics
EP3172339A1 (en) 2014-07-24 2017-05-31 Boehringer Ingelheim International GmbH Biomarkers useful in the treatment of il-23a related diseases
UA123624C2 (uk) 2014-09-03 2021-05-05 Бьорінґер Інґельхайм Інтернаціональ Ґмбх Сполука, специфічна до іл-23а та фнп-альфа, та її застосування
AR102417A1 (es) 2014-11-05 2017-03-01 Lilly Co Eli Anticuerpos biespecíficos anti-tnf- / anti-il-23
CN107206081A (zh) 2015-02-04 2017-09-26 勃林格殷格翰国际有限公司 治疗炎性疾病的方法
EP3452598A4 (en) * 2016-05-06 2020-04-29 Exicure, Inc. LIPOSOMAL SPHERICAL NUCLEIC ACID (ANS) CONSTRUCTS HAVING ANTISENSE OLIGONUCLEOTIDES (ASO) FOR THE SPECIFIC INACTIVATION OF INTERLEUKIN 17 RECEPTOR RNA
MA55149A (fr) 2018-11-20 2021-09-29 Janssen Biotech Inc Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique anti-il-23
WO2020234834A1 (en) 2019-05-23 2020-11-26 Janssen Biotech, Inc. Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha
US12577297B2 (en) 2019-09-09 2026-03-17 Boehringer Ingelheim International Gmbh Anti-IL-23p19 antibody formulations
MX2022013649A (es) * 2020-04-30 2023-02-01 Janssen Pharmaceutica Nv Métodos para identificar moduladores de la ruta de il-17.
KR20230023663A (ko) 2020-05-21 2023-02-17 얀센 바이오테크 인코포레이티드 Il-23 및 tnf 알파에 대한 항체의 병용 요법으로 염증성 장질환을 치료하는 방법
CN112390890B (zh) * 2020-11-06 2022-06-24 江苏荃信生物医药股份有限公司 一种定量检测血清中抗人白介素17单克隆抗体含量的酶联免疫分析方法
CN116183472B (zh) * 2023-04-25 2023-08-18 上海益诺思生物技术股份有限公司 Cba法检测非人类灵长类动物细胞因子的验证方法
WO2026058045A1 (en) 2024-09-12 2026-03-19 Takeda Pharmaceutical Company Limited Alpha4beta7 inhibitor and il-23 inhibitor combination therapy

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001018022A1 (en) 1999-09-03 2001-03-15 Human Genome Sciences, Inc. 52 human secreted proteins
US6060284A (en) * 1997-07-25 2000-05-09 Schering Corporation DNA encoding interleukin-B30
PE20000183A1 (es) 1997-07-25 2000-03-11 Schering Corp Citoquinas de mamiferos y reactivos relacionados
WO1999054357A1 (en) * 1998-04-14 1999-10-28 Chugai Research Institute For Molecular Medicine, Inc. Novel cytokine-like protein
US6448081B1 (en) * 2001-05-07 2002-09-10 Isis Pharmaceuticals, Inc. Antisense modulation of interleukin 12 p40 subunit expression
DE60043051D1 (de) * 1999-01-11 2009-11-12 Schering Corp Dafür kodierende polynukleotide. verwendungen
US6914128B1 (en) * 1999-03-25 2005-07-05 Abbott Gmbh & Co. Kg Human antibodies that bind human IL-12 and methods for producing
SI2168984T1 (sl) 1999-03-25 2012-12-31 Abbott Gmbh & Co. Kg Človeška protitelesa za vezavo IL-12 in postopki izdelave
US20030082734A1 (en) * 1999-06-01 2003-05-01 Dowling Lynette M. Mammalian receptor proteins; related reagents and methods
CA2388562C (en) 1999-09-09 2014-07-22 Schering Corporation Mammalian cytokines; related reagents and methods
WO2001023556A1 (en) * 1999-09-27 2001-04-05 Chugai Seiyaku Kabushiki Kaisha Novel hemopoietin receptor protein, nr12
US7422743B2 (en) * 2000-05-10 2008-09-09 Schering Corporation Mammalian receptor protein DCRS5;methods of treatment
CA2408571C (en) * 2000-05-10 2014-04-29 Schering Corporation Mammalian receptor proteins; related reagents and methods
US6902734B2 (en) * 2000-08-07 2005-06-07 Centocor, Inc. Anti-IL-12 antibodies and compositions thereof
JP3899861B2 (ja) * 2001-07-13 2007-03-28 株式会社日立製作所 光ディスク、情報再生方法及び記録方法
BRPI0408247A (pt) * 2003-03-10 2006-03-01 Schering Corp usos de antagonistas e agonistas de il-23 e reagentes relacionados
EP1689403A4 (en) 2003-11-10 2007-09-05 Synta Pharmaceuticals Corp HETEROARYL-hydrazone compounds
AU2004289304A1 (en) 2003-11-10 2005-05-26 Synta Pharmaceuticals, Corp. Pyridine compounds
AU2004289303A1 (en) * 2003-11-10 2005-05-26 Synta Pharmaceuticals, Corp. Fused heterocyclic compounds
AU2005215527B2 (en) * 2004-02-17 2011-04-07 Merck Sharp & Dohme Corp. Methods of modulating IL-23 activity; related reagents
US20050287593A1 (en) * 2004-05-03 2005-12-29 Schering Corporation Use of cytokine expression to predict skin inflammation; methods of treatment
CN1993480A (zh) 2004-05-03 2007-07-04 先灵公司 Il-17表达预测皮肤炎症的用途;治疗方法
AR051444A1 (es) * 2004-09-24 2007-01-17 Centocor Inc Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos
KR101004362B1 (ko) 2010-03-19 2010-12-28 가톨릭대학교 산학협력단 자가 면역 질환 예방 및 치료용 TNF-α와 TWEAK 이중 길항제

Similar Documents

Publication Publication Date Title
JP5477998B2 (ja) Il−17産生の阻害
JP2006514004A5 (https=)
US7560530B1 (en) IL-33 receptor
US20090142806A1 (en) Interleukin-17f antibodies and other il-17f signaling antagonists and uses therefor
EP2171044A1 (en) Th-17 cells
HK1135415A (en) Inhibition of il-17 production