JP2006513701A5 - - Google Patents
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- JP2006513701A5 JP2006513701A5 JP2004542913A JP2004542913A JP2006513701A5 JP 2006513701 A5 JP2006513701 A5 JP 2006513701A5 JP 2004542913 A JP2004542913 A JP 2004542913A JP 2004542913 A JP2004542913 A JP 2004542913A JP 2006513701 A5 JP2006513701 A5 JP 2006513701A5
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- JP
- Japan
- Prior art keywords
- probe
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- probe according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000523 sample Substances 0.000 claims 298
- 230000000295 complement Effects 0.000 claims 86
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- 102000003746 Insulin Receptor Human genes 0.000 claims 2
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- YBJHBAHKTGYVGT-ZKWXMUAHSA-N biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 2
- 229960002685 biotin Drugs 0.000 claims 2
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- 238000005406 washing Methods 0.000 claims 2
- ZSLZBFCDCINBPY-ZZSFXRQLSA-N Acetyl-CoA Natural products S(C(=O)C)CCNC(=O)CCNC(=O)[C@H](O)C(CO[P@@](=O)(O[P@](=O)(OC[C@@H]1[C@@H](OP(=O)(O)O)[C@H](O)[C@@H](n2c3ncnc(N)c3nc2)O1)O)O)(C)C ZSLZBFCDCINBPY-ZZSFXRQLSA-N 0.000 claims 1
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- 229940096919 Glycogen Drugs 0.000 claims 1
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- BYSGBSNPRWKUQH-UJDJLXLFSA-N Glycogen Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@@H](O)[C@@H](O[C@@H]2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)O1 BYSGBSNPRWKUQH-UJDJLXLFSA-N 0.000 claims 1
- 102000003886 Glycoproteins Human genes 0.000 claims 1
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- 108020005128 Glycosidases Proteins 0.000 claims 1
- 101710024478 HLCS Proteins 0.000 claims 1
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- 208000006454 Hepatitis Diseases 0.000 claims 1
- 208000009889 Herpes Simplex Diseases 0.000 claims 1
- 229940088597 Hormone Drugs 0.000 claims 1
- 125000002842 L-seryl group Chemical group O=C([*])[C@](N([H])[H])([H])C([H])([H])O[H] 0.000 claims 1
- 102100000794 LIG4 Human genes 0.000 claims 1
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- 102100005410 LINE-1 retrotransposable element ORF2 protein Human genes 0.000 claims 1
- 229940040461 Lipase Drugs 0.000 claims 1
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- 101700067074 MAPK Proteins 0.000 claims 1
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- 102100018545 MYLK Human genes 0.000 claims 1
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- 241000124008 Mammalia Species 0.000 claims 1
- 101700080605 NUC1 Proteins 0.000 claims 1
- 241000244206 Nematoda Species 0.000 claims 1
- 229940067631 Phospholipids Drugs 0.000 claims 1
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 claims 1
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 claims 1
- 241000224016 Plasmodium Species 0.000 claims 1
- 102000008662 Polynucleotide 3'-phosphatase Human genes 0.000 claims 1
- 108050000468 Polynucleotide 3'-phosphatase Proteins 0.000 claims 1
- 102000002727 Protein Tyrosine Phosphatases Human genes 0.000 claims 1
- 108020000494 Protein Tyrosine Phosphatases Proteins 0.000 claims 1
- 102000014400 SH2 domains Human genes 0.000 claims 1
- 108050003452 SH2 domains Proteins 0.000 claims 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 1
- 206010039491 Sarcoma Diseases 0.000 claims 1
- 241000700584 Simplexvirus Species 0.000 claims 1
- 231100000765 Toxin Toxicity 0.000 claims 1
- 241000710772 Yellow fever virus Species 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K [O-]P([O-])([O-])=O Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 125000000266 alpha-aminoacyl group Chemical group 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000003115 biocidal Effects 0.000 claims 1
- 101700078248 birA Proteins 0.000 claims 1
- 101710024496 birA/coaX Proteins 0.000 claims 1
- 239000007853 buffer solution Substances 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 235000014633 carbohydrates Nutrition 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 230000001268 conjugating Effects 0.000 claims 1
- 230000001419 dependent Effects 0.000 claims 1
- 239000002532 enzyme inhibitor Substances 0.000 claims 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 claims 1
- 150000004676 glycans Polymers 0.000 claims 1
- 231100000283 hepatitis Toxicity 0.000 claims 1
- 239000005556 hormone Substances 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 238000011065 in-situ storage Methods 0.000 claims 1
- 102000006029 inositol monophosphatase family Human genes 0.000 claims 1
- 108020003233 inositol monophosphatase family Proteins 0.000 claims 1
- 102000004882 lipase Human genes 0.000 claims 1
- 108090001060 lipase Proteins 0.000 claims 1
- 235000019421 lipase Nutrition 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000003068 molecular probe Substances 0.000 claims 1
- 230000003533 narcotic Effects 0.000 claims 1
- 101700006494 nucA Proteins 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000008191 permeabilizing agent Substances 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 150000003916 phosphatidylinositol 3,4,5-trisphosphates Chemical class 0.000 claims 1
- 150000003905 phosphatidylinositols Chemical class 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-N phosphoric acid Chemical group OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims 1
- 229920000023 polynucleotide Polymers 0.000 claims 1
- 239000002157 polynucleotide Substances 0.000 claims 1
- 108010035192 polynucleotide 5'-phosphatase Proteins 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 150000004804 polysaccharides Polymers 0.000 claims 1
- OZAIFHULBGXAKX-UHFFFAOYSA-N precursor Substances N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 claims 1
- 101710024887 rl Proteins 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 101700045897 spk-1 Proteins 0.000 claims 1
- 239000003053 toxin Substances 0.000 claims 1
- 108060008633 trl1 Proteins 0.000 claims 1
- 241001529453 unidentified herpesvirus Species 0.000 claims 1
- 230000003612 virological Effects 0.000 claims 1
- 229940051021 yellow-fever virus Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41786402P | 2002-10-11 | 2002-10-11 | |
| PCT/KR2003/002101 WO2004033476A1 (fr) | 2002-10-11 | 2003-10-11 | Systeme de detection de cibles avec sonde sensible par sa conformation, comprenant un transducteur de signaux a base d'acides nucleiques |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010015946A Division JP2010099090A (ja) | 2002-10-11 | 2010-01-27 | 核酸ベースのシグナルトランスデューサーを含む立体構造的に敏感なプローブを有する標的検出システム |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006513701A JP2006513701A (ja) | 2006-04-27 |
| JP2006513701A5 true JP2006513701A5 (fr) | 2006-11-30 |
Family
ID=32094107
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004542913A Pending JP2006513701A (ja) | 2002-10-11 | 2003-10-11 | 核酸ベースのシグナルトランスデューサーを含む立体構造的に敏感なプローブを有する標的検出システム |
| JP2010015946A Abandoned JP2010099090A (ja) | 2002-10-11 | 2010-01-27 | 核酸ベースのシグナルトランスデューサーを含む立体構造的に敏感なプローブを有する標的検出システム |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010015946A Abandoned JP2010099090A (ja) | 2002-10-11 | 2010-01-27 | 核酸ベースのシグナルトランスデューサーを含む立体構造的に敏感なプローブを有する標的検出システム |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1558626A4 (fr) |
| JP (2) | JP2006513701A (fr) |
| AU (1) | AU2003269522A1 (fr) |
| WO (1) | WO2004033476A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2006075735A1 (ja) * | 2005-01-14 | 2008-06-12 | 日本碍子株式会社 | アレイおよびハイブリダイズ方法 |
| JP2008531052A (ja) * | 2005-02-28 | 2008-08-14 | ジェン−プローブ・インコーポレーテッド | 核酸ハイブリダイゼーションスイッチプローブを用いて被分析体を検出するための組成物及び方法 |
| JP2011067174A (ja) * | 2009-09-28 | 2011-04-07 | Fujitsu Ltd | 標的検出装置及びその製造方法 |
| FR2998969B1 (fr) * | 2012-12-04 | 2015-01-09 | Univ Limoges | Utilisation de biotine greffee pour le dosage de metaux dans une solution |
| WO2016163345A1 (fr) * | 2015-04-07 | 2016-10-13 | コニカミノルタ株式会社 | Sonde d'acide nucléique |
| BR112020016347A2 (pt) | 2018-02-21 | 2021-01-12 | Bristol-Myers Squibb Company | Oligonucleotídeos antisense de camk2d e seus usos |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0232967B1 (fr) * | 1986-01-10 | 1993-04-28 | Amoco Corporation | Dosage homogène concomitant |
| US5283174A (en) * | 1987-09-21 | 1994-02-01 | Gen-Probe, Incorporated | Homogenous protection assay |
| WO1991005261A1 (fr) * | 1989-10-04 | 1991-04-18 | E.I. Du Pont De Nemours And Company | Methode d'analyse pour des complexes de cibles biologiques situes a la surface d'un capteur biologique |
| US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| US6337183B1 (en) * | 1995-09-08 | 2002-01-08 | Scriptgen Pharmaceuticals, Inc. | Screen for compounds with affinity for nucleic acids |
| US6255048B1 (en) * | 1996-06-10 | 2001-07-03 | Laboratory Of Molecular Biophotonics | Highly sensitive fluoroassay |
| US6361942B1 (en) * | 1998-03-24 | 2002-03-26 | Boston Probes, Inc. | Method, kits and compositions pertaining to detection complexes |
| WO2000011446A2 (fr) * | 1998-08-21 | 2000-03-02 | University Of Virginia Patent Foundation | Biocapteur generateur de signaux base sur les oligonucleotides |
| DE19950969A1 (de) * | 1999-10-22 | 2001-05-10 | Aventis Res & Tech Gmbh & Co | Doppelstrang-Nukleinsäure-Sonden und deren Verwendung |
| US6753141B2 (en) * | 2000-01-25 | 2004-06-22 | The University Of Utah | Simultaneous screening and identification of sequence alterations from amplified target |
| US6743640B2 (en) * | 2000-05-08 | 2004-06-01 | Qtl Biosystems Llc | Fluorescent polymer-QTL approach to biosensing |
-
2003
- 2003-10-11 AU AU2003269522A patent/AU2003269522A1/en not_active Abandoned
- 2003-10-11 EP EP03751517A patent/EP1558626A4/fr not_active Withdrawn
- 2003-10-11 JP JP2004542913A patent/JP2006513701A/ja active Pending
- 2003-10-11 WO PCT/KR2003/002101 patent/WO2004033476A1/fr active Application Filing
-
2010
- 2010-01-27 JP JP2010015946A patent/JP2010099090A/ja not_active Abandoned
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