JP2006512893A - 治療用エピトープ及びそれらの使用 - Google Patents

治療用エピトープ及びそれらの使用 Download PDF

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Publication number
JP2006512893A
JP2006512893A JP2004511341A JP2004511341A JP2006512893A JP 2006512893 A JP2006512893 A JP 2006512893A JP 2004511341 A JP2004511341 A JP 2004511341A JP 2004511341 A JP2004511341 A JP 2004511341A JP 2006512893 A JP2006512893 A JP 2006512893A
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JP
Japan
Prior art keywords
gliadin
cell
epitope
celiac disease
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2004511341A
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English (en)
Japanese (ja)
Inventor
アンダーソン,ロバート・ポール
ヒル,エイドリアン・ビビアン・シントン
ジェウェル,デレック・パーリー
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Oxford University Innovation Ltd
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Oxford University Innovation Ltd
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Publication date
Application filed by Oxford University Innovation Ltd filed Critical Oxford University Innovation Ltd
Publication of JP2006512893A publication Critical patent/JP2006512893A/ja
Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2004511341A 2002-06-05 2003-06-05 治療用エピトープ及びそれらの使用 Withdrawn JP2006512893A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0212885.8A GB0212885D0 (en) 2002-06-05 2002-06-05 Therapeutic epitopes and uses thereof
PCT/GB2003/002450 WO2003104273A2 (en) 2002-06-05 2003-06-05 Therapeutic epitopes and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010110683A Division JP5635302B2 (ja) 2002-06-05 2010-05-12 治療用エピトープ及びそれらの使用

Publications (1)

Publication Number Publication Date
JP2006512893A true JP2006512893A (ja) 2006-04-20

Family

ID=9937994

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2004511341A Withdrawn JP2006512893A (ja) 2002-06-05 2003-06-05 治療用エピトープ及びそれらの使用
JP2010110683A Expired - Lifetime JP5635302B2 (ja) 2002-06-05 2010-05-12 治療用エピトープ及びそれらの使用
JP2013021737A Expired - Lifetime JP6055689B2 (ja) 2002-06-05 2013-02-06 治療用エピトープ及びそれらの使用
JP2014162664A Expired - Lifetime JP5977293B2 (ja) 2002-06-05 2014-08-08 治療用エピトープ及びそれらの使用
JP2014198382A Pending JP2015052599A (ja) 2002-06-05 2014-09-29 治療用エピトープ及びそれらの使用
JP2016037111A Expired - Lifetime JP6438423B2 (ja) 2002-06-05 2016-02-29 治療用エピトープ及びそれらの使用

Family Applications After (5)

Application Number Title Priority Date Filing Date
JP2010110683A Expired - Lifetime JP5635302B2 (ja) 2002-06-05 2010-05-12 治療用エピトープ及びそれらの使用
JP2013021737A Expired - Lifetime JP6055689B2 (ja) 2002-06-05 2013-02-06 治療用エピトープ及びそれらの使用
JP2014162664A Expired - Lifetime JP5977293B2 (ja) 2002-06-05 2014-08-08 治療用エピトープ及びそれらの使用
JP2014198382A Pending JP2015052599A (ja) 2002-06-05 2014-09-29 治療用エピトープ及びそれらの使用
JP2016037111A Expired - Lifetime JP6438423B2 (ja) 2002-06-05 2016-02-29 治療用エピトープ及びそれらの使用

Country Status (15)

Country Link
US (2) US10053497B2 (enExample)
EP (3) EP1513873B1 (enExample)
JP (6) JP2006512893A (enExample)
AU (1) AU2003244771B2 (enExample)
CA (1) CA2488218C (enExample)
CY (1) CY1115730T1 (enExample)
DK (1) DK1513873T3 (enExample)
ES (1) ES2510440T3 (enExample)
GB (1) GB0212885D0 (enExample)
MX (2) MXPA04012117A (enExample)
NZ (1) NZ537226A (enExample)
PT (1) PT1513873E (enExample)
SI (1) SI1513873T1 (enExample)
WO (1) WO2003104273A2 (enExample)
ZA (1) ZA200409740B (enExample)

Cited By (9)

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JP2012510431A (ja) * 2008-11-30 2012-05-10 イミューサンティー インコーポレーテッド セリアック病の処置のための組成物および方法
WO2017146118A1 (ja) * 2016-02-23 2017-08-31 田中貴金属工業株式会社 グリアジン検出用免疫クロマト分析装置、免疫クロマト分析キットおよび免疫クロマト分析方法
JP2017532544A (ja) * 2014-09-10 2017-11-02 ヴィブラント ホールディングス リミテッド ライアビリティ カンパニー セリアック病に関するペプチドマイクロアレイおよび新規バイオマーカー
US10449228B2 (en) 2013-09-10 2019-10-22 Immusant, Inc. Dosage of a gluten peptide composition
US11168365B2 (en) 2017-05-26 2021-11-09 Vibrant Holdings, Llc Photoactive compounds and methods for biomolecule detection and sequencing
JP2022538647A (ja) * 2019-07-04 2022-09-05 ウッコ インコーポレイテッド 脱エピトープ化されたアルファグリアジン、ならびにセリアック病およびグルテン過敏症の管理のためのその使用
US11674956B2 (en) 2012-09-28 2023-06-13 Vibrant Holdings, Llc Methods, systems, and arrays for biomolecular analysis
US12319712B2 (en) 2018-05-09 2025-06-03 Vibrant Holdings, Llc Methods of synthesizing a polynucleotide array using photoactivated agents
US12454771B2 (en) 2012-02-07 2025-10-28 Vibrant Holdings Llc Substrates, peptide arrays, and methods

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GB9923306D0 (en) 1999-10-01 1999-12-08 Isis Innovation Diagnostic and therapeutic epitope, and transgenic plant
US8143210B2 (en) 2002-02-14 2012-03-27 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for celiac sprue
EP1572127B2 (en) * 2002-02-14 2014-10-29 The Board of Trustees of the Leland Stanford Junior University Enzyme treatment of foodstuffs for celiac sprue
US7202216B2 (en) * 2002-05-14 2007-04-10 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for celiac sprue
WO2003096984A2 (en) * 2002-05-14 2003-11-27 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for celiac sprue
US7462688B2 (en) * 2002-05-14 2008-12-09 The Board Of Trustees Of The Leland Stanford Junior University Peptides for diagnostic and therapeutic methods for celiac sprue
US7265093B2 (en) * 2002-05-14 2007-09-04 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for Celiac Sprue
GB0212885D0 (en) * 2002-06-05 2002-07-17 Isis Innovation Therapeutic epitopes and uses thereof
DK1563300T3 (da) * 2002-11-20 2012-07-23 Univ Leland Stanford Junior Diagnostisk fremgangsmåde til cøliaki
US7579313B2 (en) * 2003-11-18 2009-08-25 The Board Of Trustees Of The Leland Stanford Junior University Transglutaminase inhibitors and methods of use thereof
ATE497782T1 (de) 2004-04-16 2011-02-15 Univ Alberta Anti-gluten-eigelb-antikörper zur behanldung von zoeliakie
US7563864B2 (en) * 2004-04-26 2009-07-21 Celiac Sprue Research Foundation Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten
US7534426B2 (en) * 2004-04-26 2009-05-19 The Board Of Trustees Of The Leland Stanford Junior University Glutenase enzyme assays
US7628985B2 (en) * 2004-04-26 2009-12-08 The Board Of Regents Of The Leland Stanford Junior University Therapeutic enzyme formulations and uses thereof in celiac sprue and/or dermatitis herpetoformis
EP1755639B1 (en) * 2004-04-28 2017-08-16 BTG International Limited Epitopes related to coeliac disease
US10105437B2 (en) 2004-04-28 2018-10-23 Btg International Limited Epitopes related to coeliac disease
AU2011247868B2 (en) * 2004-04-28 2014-05-22 Btg International Limited Epitopes related to coeliac disease
MX2009009780A (es) 2007-03-16 2010-05-20 Univ Leland Stanford Junior Terapia de enzima de combinacion para la digestion de gluten dietetico.
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AU2013204429B9 (en) * 2008-11-30 2017-01-05 Immusant, Inc. Compositions and methods for treatment of celiac disease
AU2011289579B2 (en) 2010-08-10 2016-11-17 Ecole Polytechnique Federale De Lausanne Erythrocyte-binding therapeutics
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
WO2012108827A1 (en) * 2011-02-08 2012-08-16 Phadia Ab Wheat antigens and peptides for diagnosis of wheat induced hypersensitivity
ES2402286B1 (es) * 2011-09-29 2014-03-04 Universidad De Valladolid Péptido inmunogénico del gluten y sus aplicaciones.
US10286376B2 (en) 2012-11-14 2019-05-14 Vibrant Holdings, Llc Substrates, systems, and methods for array synthesis and biomolecular analysis
EP2956771B1 (en) 2013-02-15 2020-04-08 Vibrant Holdings, LLC Methods and compositions for amplified electrochemiluminescence detection
US10046056B2 (en) 2014-02-21 2018-08-14 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
US10946079B2 (en) 2014-02-21 2021-03-16 Ecole Polytechnique Federale De Lausanne Glycotargeting therapeutics
US10953101B2 (en) 2014-02-21 2021-03-23 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
EP3909603A1 (en) 2014-02-21 2021-11-17 Ecole Polytechnique Fédérale de Lausanne (EPFL) Glycotargeting therapeutics
WO2015164747A1 (en) 2014-04-24 2015-10-29 Immusant, Inc. Methods for diagnosing celiac disease using circulating cytokines/chemokines
AU2015323979A1 (en) 2014-09-29 2017-05-18 Immusant, Inc. Use of HLA genetic status to assess or select treatment of celiac disease
HK1244821A1 (zh) 2014-11-21 2018-08-17 Immusant Inc. 用於治疗和诊断1型糖尿病中使用的肽
EP3313868A1 (en) * 2015-06-26 2018-05-02 Institut National De La Recherche Agronomique (INRA) Immunogenic composition
EP3109255A1 (en) 2015-06-26 2016-12-28 Institut National De La Recherche Agronomique Immunogenic composition
US11253579B2 (en) 2017-06-16 2022-02-22 The University Of Chicago Compositions and methods for inducing immune tolerance
JP6568193B2 (ja) * 2017-12-19 2019-08-28 ホーユー株式会社 エピトープ
JP2021528371A (ja) 2018-05-09 2021-10-21 ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago 免疫寛容に関する組成物および方法
EP4034144A1 (en) 2019-09-27 2022-08-03 Intrexon Actobiotics NV d/b/a Precigen Actobio Treatment of celiac disease
GB202113858D0 (en) * 2021-09-28 2021-11-10 Nextera As Peptides
CN115124606B (zh) * 2022-06-27 2025-03-28 上海理工大学 含有氨基酸结构pqqp的寡肽及其制备方法和应用

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JP7256229B2 (ja) 2014-09-10 2023-04-11 ヴィブラント ホールディングス リミテッド ライアビリティ カンパニー セリアック病に関するペプチドマイクロアレイおよび新規バイオマーカー
JP2021144040A (ja) * 2014-09-10 2021-09-24 ヴィブラント ホールディングス リミテッド ライアビリティ カンパニー セリアック病に関するペプチドマイクロアレイおよび新規バイオマーカー
JP7781813B2 (ja) 2014-09-10 2025-12-08 ヴィブラント ホールディングス リミテッド ライアビリティ カンパニー セリアック病に関するペプチドマイクロアレイおよび新規バイオマーカー
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