DK1513873T3 - Terapeutiske epitoper og anvendelser deraf - Google Patents

Terapeutiske epitoper og anvendelser deraf

Info

Publication number
DK1513873T3
DK1513873T3 DK03738256.1T DK03738256T DK1513873T3 DK 1513873 T3 DK1513873 T3 DK 1513873T3 DK 03738256 T DK03738256 T DK 03738256T DK 1513873 T3 DK1513873 T3 DK 1513873T3
Authority
DK
Denmark
Prior art keywords
applications
therapeutic epitopes
epitopes
therapeutic
Prior art date
Application number
DK03738256.1T
Other languages
Danish (da)
English (en)
Inventor
R P Walter & Eliza Hall Institute Anderson
A V S Wellcome Trust Cntrfor Humangene Hill
Derek Parry Gastroenterology Unit Jewell
Original Assignee
Isis Innovation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Innovation filed Critical Isis Innovation
Application granted granted Critical
Publication of DK1513873T3 publication Critical patent/DK1513873T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK03738256.1T 2002-06-05 2003-06-05 Terapeutiske epitoper og anvendelser deraf DK1513873T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0212885.8A GB0212885D0 (en) 2002-06-05 2002-06-05 Therapeutic epitopes and uses thereof
PCT/GB2003/002450 WO2003104273A2 (en) 2002-06-05 2003-06-05 Therapeutic epitopes and uses thereof

Publications (1)

Publication Number Publication Date
DK1513873T3 true DK1513873T3 (da) 2014-11-03

Family

ID=9937994

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03738256.1T DK1513873T3 (da) 2002-06-05 2003-06-05 Terapeutiske epitoper og anvendelser deraf

Country Status (15)

Country Link
US (2) US10053497B2 (enExample)
EP (3) EP1513873B1 (enExample)
JP (6) JP2006512893A (enExample)
AU (1) AU2003244771B2 (enExample)
CA (1) CA2488218C (enExample)
CY (1) CY1115730T1 (enExample)
DK (1) DK1513873T3 (enExample)
ES (1) ES2510440T3 (enExample)
GB (1) GB0212885D0 (enExample)
MX (2) MXPA04012117A (enExample)
NZ (1) NZ537226A (enExample)
PT (1) PT1513873E (enExample)
SI (1) SI1513873T1 (enExample)
WO (1) WO2003104273A2 (enExample)
ZA (1) ZA200409740B (enExample)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9923306D0 (en) 1999-10-01 1999-12-08 Isis Innovation Diagnostic and therapeutic epitope, and transgenic plant
US8143210B2 (en) 2002-02-14 2012-03-27 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for celiac sprue
US7303871B2 (en) 2002-02-14 2007-12-04 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for Celiac Sprue
WO2004045392A2 (en) 2002-11-20 2004-06-03 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic method for celiac sprue
US7265093B2 (en) * 2002-05-14 2007-09-04 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for Celiac Sprue
AU2003234597A1 (en) * 2002-05-14 2003-12-02 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for celiac sprue
US7462688B2 (en) * 2002-05-14 2008-12-09 The Board Of Trustees Of The Leland Stanford Junior University Peptides for diagnostic and therapeutic methods for celiac sprue
US7202216B2 (en) * 2002-05-14 2007-04-10 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for celiac sprue
GB0212885D0 (en) 2002-06-05 2002-07-17 Isis Innovation Therapeutic epitopes and uses thereof
US7579313B2 (en) 2003-11-18 2009-08-25 The Board Of Trustees Of The Leland Stanford Junior University Transglutaminase inhibitors and methods of use thereof
WO2005099753A1 (en) * 2004-04-16 2005-10-27 The Govenors Of The University Of Alberta Anti-gluten egg yolk antibodies for the treatment of celiac disease
US7628985B2 (en) * 2004-04-26 2009-12-08 The Board Of Regents Of The Leland Stanford Junior University Therapeutic enzyme formulations and uses thereof in celiac sprue and/or dermatitis herpetoformis
US7534426B2 (en) * 2004-04-26 2009-05-19 The Board Of Trustees Of The Leland Stanford Junior University Glutenase enzyme assays
US7563864B2 (en) * 2004-04-26 2009-07-21 Celiac Sprue Research Foundation Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten
EP1755639B1 (en) 2004-04-28 2017-08-16 BTG International Limited Epitopes related to coeliac disease
AU2011247868B2 (en) * 2004-04-28 2014-05-22 Btg International Limited Epitopes related to coeliac disease
US10105437B2 (en) 2004-04-28 2018-10-23 Btg International Limited Epitopes related to coeliac disease
AU2008229448B2 (en) * 2007-03-16 2013-01-24 The Board Of Trustees Of The Leland Stanford Junior University Combination enzyme therapy for digestion of dietary gluten
US8282928B2 (en) 2007-05-30 2012-10-09 The Governors Of The University Of Alberta Anti-gluten egg yolk antibodies for the treatment of celiac disease
DE102007044673A1 (de) * 2007-09-18 2009-03-19 Zimmer, Klaus-Peter, Prof. Dr. med. Impfstoff zur Behandlung von Zöliakie und Verfahren zur Herstellung des Impfstoffes, Verwendung einer mit einem bakteriellen Toxin konjugierten Peptidsequenz zur Aktivierung des Immunsystems gegen Prolamine sowie Designerpeptid
PT2367561E (pt) * 2008-11-30 2015-10-23 Immusant Inc Composições e métodos para o tratamento da doença celíaca
AU2013204429B9 (en) * 2008-11-30 2017-01-05 Immusant, Inc. Compositions and methods for treatment of celiac disease
AU2011289579B2 (en) 2010-08-10 2016-11-17 Ecole Polytechnique Federale De Lausanne Erythrocyte-binding therapeutics
US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
US20140037661A1 (en) * 2011-02-08 2014-02-06 Phadia Ab Wheat Antigens and Peptides for Diagnosis of Wheat Induced Hypersensitivity
ES2402286B1 (es) * 2011-09-29 2014-03-04 Universidad De Valladolid Péptido inmunogénico del gluten y sus aplicaciones.
CA3191015A1 (en) 2012-02-07 2013-08-15 Vibrant Holdings, Llc Substrates, peptide arrays, and methods
US10006909B2 (en) 2012-09-28 2018-06-26 Vibrant Holdings, Llc Methods, systems, and arrays for biomolecular analysis
US10286376B2 (en) 2012-11-14 2019-05-14 Vibrant Holdings, Llc Substrates, systems, and methods for array synthesis and biomolecular analysis
EP2956771B1 (en) 2013-02-15 2020-04-08 Vibrant Holdings, LLC Methods and compositions for amplified electrochemiluminescence detection
WO2015038624A1 (en) 2013-09-10 2015-03-19 Immusant, Inc. Dosage of a gluten peptide composition
US10953101B2 (en) 2014-02-21 2021-03-23 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
LT3107563T (lt) 2014-02-21 2021-07-12 Ecole Polytechnique Fédérale De Lausanne (Epfl) Epfl-Tto Gliko-nukreipiantys terapiniai agenai
US10046056B2 (en) 2014-02-21 2018-08-14 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
US10946079B2 (en) 2014-02-21 2021-03-16 Ecole Polytechnique Federale De Lausanne Glycotargeting therapeutics
WO2015164747A1 (en) 2014-04-24 2015-10-29 Immusant, Inc. Methods for diagnosing celiac disease using circulating cytokines/chemokines
AU2015314934A1 (en) * 2014-09-10 2017-04-20 Vibrant Holdings, Llc Peptide microarrays and novel biomarkers for celiac disease
US10370718B2 (en) 2014-09-29 2019-08-06 Immusant, Inc. Use of HLA genetic status to assess or select treatment of celiac disease
EP3221344A2 (en) 2014-11-21 2017-09-27 Immusant Inc. Peptides for use in treatment and diagnosis of type 1 diabetes
EP3868777A1 (en) * 2015-06-26 2021-08-25 Institut national de recherche pour l'agriculture, l'alimentation et l'environnement Immunogenic composition
EP3109255A1 (en) 2015-06-26 2016-12-28 Institut National De La Recherche Agronomique Immunogenic composition
AU2017222910A1 (en) * 2016-02-23 2018-09-13 Tanaka Kikinzoku Kogyo K.K. Immunochromatographic analysis device for detecting gliadin, immunochromatrographic analysis kit and immunochromatographic analysis method
WO2018218250A2 (en) 2017-05-26 2018-11-29 Vibrant Holdings, Llc Photoactive compounds and methods for biomolecule detection and sequencing
US11253579B2 (en) 2017-06-16 2022-02-22 The University Of Chicago Compositions and methods for inducing immune tolerance
JP6568193B2 (ja) * 2017-12-19 2019-08-28 ホーユー株式会社 エピトープ
JP7422087B2 (ja) 2018-05-09 2024-01-25 ヴィブラント ホールディングス リミテッド ライアビリティ カンパニー 光活性化された作用物質を使用してポリヌクレオチドアレイを合成する方法
EA202092723A1 (ru) 2018-05-09 2021-04-09 Зе Юниверсити Оф Чикаго Композиции и способы, касающиеся иммунной толерантности
AU2020300101A1 (en) * 2019-07-04 2022-02-17 Ukko Inc. De-epitoped alpha gliadin and use of same for the management of celiac disease and gluten sensitivity
CN114761028A (zh) 2019-09-27 2022-07-15 英特瑞克斯顿阿克图比奥帝克斯有限公司 乳糜泻的治疗
GB202113858D0 (en) * 2021-09-28 2021-11-10 Nextera As Peptides
CN115124606B (zh) * 2022-06-27 2025-03-28 上海理工大学 含有氨基酸结构pqqp的寡肽及其制备方法和应用

Family Cites Families (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4459355A (en) 1982-07-12 1984-07-10 International Paper Company Method for transforming plant cells
US4536475A (en) 1982-10-05 1985-08-20 Phytogen Plant vector
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
JPS6047683A (ja) 1983-08-24 1985-03-15 Kirin Brewery Co Ltd プロモ−タ−
US5100792A (en) 1984-11-13 1992-03-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues
US5036006A (en) 1984-11-13 1991-07-30 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US4943674A (en) 1987-05-26 1990-07-24 Calgene, Inc. Fruit specific transcriptional factors
DK162399C (da) 1986-01-28 1992-03-23 Danisco Fremgangsmaade til ekspression af gener i baelgplanteceller, dna-fragment, rekombineret dna-fragment samt plasmid til brug ved udoevelsen af fremgangsmaaden
ES2018274T5 (es) 1986-03-11 1996-12-16 Plant Genetic Systems Nv Celulas vegetales resistentes a los inhibidores de glutamina sintetasa, preparadas por ingenieria genetica.
US5107065A (en) 1986-03-28 1992-04-21 Calgene, Inc. Anti-sense regulation of gene expression in plant cells
US5187073A (en) 1986-06-30 1993-02-16 The University Of Toledo Process for transforming gramineae and the products thereof
US5177010A (en) 1986-06-30 1993-01-05 University Of Toledo Process for transforming corn and the products thereof
NZ221259A (en) 1986-07-31 1990-05-28 Calgene Inc Seed specific transcriptional regulation
EP0267159A3 (de) 1986-11-07 1990-05-02 Ciba-Geigy Ag Verfahren zur genetischen Modifikation monokotyler Pflanzen
US4866247A (en) 1986-12-11 1989-09-12 The Lincoln Electric Company Apparatus and method of short circuiting arc welding
US4971908A (en) 1987-05-26 1990-11-20 Monsanto Company Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthase
US5356799A (en) 1988-02-03 1994-10-18 Pioneer Hi-Bred International, Inc. Antisense gene systems of pollination control for hybrid seed production
US5371014A (en) 1988-02-12 1994-12-06 Daicel Chemical Industries, Ltd. Process for the production of optically active 2-hydroxy acid esters using microbes to reduce the 2-oxo precursor
US5179022A (en) 1988-02-29 1993-01-12 E. I. Du Pont De Nemours & Co. Biolistic apparatus for delivering substances into cells and tissues in a non-lethal manner
US5614395A (en) 1988-03-08 1997-03-25 Ciba-Geigy Corporation Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
US5250515A (en) 1988-04-11 1993-10-05 Monsanto Company Method for improving the efficacy of insect toxins
US5565346A (en) 1988-07-27 1996-10-15 Calgene, Inc. Transformation and regeneration system for legumes
US5428146A (en) 1988-11-07 1995-06-27 Max-Planck-Gesellschaft Zur Forderung Wound-stimulated DNA-sequence from solanum tuberosum and its use
US5110732A (en) 1989-03-14 1992-05-05 The Rockefeller University Selective gene expression in plants
US5086169A (en) 1989-04-20 1992-02-04 The Research Foundation Of State University Of New York Isolated pollen-specific promoter of corn
US5629183A (en) 1989-05-08 1997-05-13 The United States Of America As Represented By The Secretary Of Agriculture Plant transformation by gene transfer into pollen
US5097025A (en) 1989-08-01 1992-03-17 The Rockefeller University Plant promoters
US7705215B1 (en) 1990-04-17 2010-04-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US5550318A (en) 1990-04-17 1996-08-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
ATE160174T1 (de) 1989-08-09 1997-11-15 Dekalb Genetics Corp Methoden und zusammensetzungen für die herstellung von stabil transformierten, fruchtbaren mais pflanzen und zellen dafür
US4919813A (en) 1989-08-25 1990-04-24 The United States Of America As Represented By The Department Of Energy Photoenhanced anaerobic digestion of organic acids
ES2215986T3 (es) 1989-10-27 2004-10-16 The Salk Institute For Biological Studies Composiciones receptoras de glutamato y metodos.
US5589583A (en) 1990-01-11 1996-12-31 Monsanto Company Plant promoter
HU220773B1 (hu) 1990-01-22 2002-05-28 Dekalb Genetics Corporation Eljárás termő transzgenikus kukoricanövények előállítására
US5484956A (en) 1990-01-22 1996-01-16 Dekalb Genetics Corporation Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin
EP0442174A1 (en) 1990-02-13 1991-08-21 Pioneer Hi-Bred International, Inc. Stable transformation of plant cells
US5618988A (en) 1990-03-02 1997-04-08 Amoco Corporation Enhanced carotenoid accumulation in storage organs of genetically engineered plants
US5204253A (en) 1990-05-29 1993-04-20 E. I. Du Pont De Nemours And Company Method and apparatus for introducing biological substances into living cells
US5187267A (en) 1990-06-19 1993-02-16 Calgene, Inc. Plant proteins, promoters, coding sequences and use
WO1992000377A1 (en) 1990-06-25 1992-01-09 Monsanto Company Glyphosate tolerant plants
US5932782A (en) 1990-11-14 1999-08-03 Pioneer Hi-Bred International, Inc. Plant transformation method using agrobacterium species adhered to microprojectiles
NZ239977A (en) 1990-11-14 1993-08-26 Pioneer Hi Bred Int Transforming plants by the use of agrobacterium
EP0559742A1 (en) 1990-11-26 1993-09-15 E.I. Du Pont De Nemours And Company Herbicidal oxazine ethers
US5459252A (en) 1991-01-31 1995-10-17 North Carolina State University Root specific gene promoter
WO1992013957A1 (en) 1991-02-07 1992-08-20 Plant Genetic Systems, N.V. Stamen-specific promoters from corn
IL101508A0 (en) 1991-04-08 1992-12-30 Rhone Poulenc Agrochimie Chimeric plant genes based on upstream regulatory elements of helianthinin
AU664034B2 (en) 1991-05-15 1995-11-02 Monsanto Company Method of creating a transformed rice plant
AU2515592A (en) 1991-08-23 1993-03-16 University Of Florida A novel method for the production of transgenic plants
DE69334225D1 (de) 1992-07-07 2008-07-31 Japan Tobacco Inc Verfahren zur transformation einer monokotyledon pflanze
WO1994010307A1 (en) 1992-10-29 1994-05-11 Medical Research Council Transcription factor dp-1
US5389226A (en) 1992-12-17 1995-02-14 Amorphous Technologies International, Inc. Electrodeposition of nickel-tungsten amorphous and microcrystalline coatings
TW360548B (en) 1993-04-08 1999-06-11 Powderject Res Ltd Products for therapeutic use
WO1994025613A1 (en) 1993-05-03 1994-11-10 Cornell Research Foundation, Inc. Isolated dna elements that direct pistil-specific and anther-specific gene expression and methods of using same
US5670349A (en) 1993-08-02 1997-09-23 Virginia Tech Intellectual Properties, Inc. HMG2 promoter expression system and post-harvest production of gene products in plants and plant cell cultures
CA2148499C (en) 1993-09-03 2006-07-11 Hideaki Saito Method for transforming monocotyledons using scutella of immature embryos
US5495007A (en) 1994-04-29 1996-02-27 Thompson; Gary A. Phloem-specific promoter
US5633363A (en) 1994-06-03 1997-05-27 Iowa State University, Research Foundation In Root preferential promoter
US5646333A (en) 1994-09-02 1997-07-08 Drexel University Plant promoter useful for directing the expression of foreign proteins to the plant epidermis
HUT76355A (en) 1995-11-24 1997-08-28 Bay Zoltan Alkalmazott Kutatas Plant gene-expression vector family based on dna fragments regulating alfalfa h3 histon gene variant (ms h3g1)
US6036983A (en) 1996-05-20 2000-03-14 Novo Nordisk A/S Method of obtaining protein hydrolysates
CA2257972A1 (en) 1996-06-13 1997-12-18 Consejo Superior De Investigaciones Cientificas Plant proteins
GB9624456D0 (en) 1996-11-25 1997-01-15 Isis Innovation Assay method
US5959175A (en) 1997-04-09 1999-09-28 Thomas; Terry L. Sunflower albumin 5' regulatory region for the modification of plant seed lipid composition
US5977436A (en) 1997-04-09 1999-11-02 Rhone Poulenc Agrochimie Oleosin 5' regulatory region for the modification of plant seed lipid composition
ES2132025B1 (es) 1997-06-12 2000-12-01 Consejo Superior Investigacion Proteinas urag de las plantas.
EP0905518A1 (en) * 1997-09-23 1999-03-31 Academisch Ziekenhuis Leiden Peptides specific for gluten-sensitive T-cells and use thereof
US6100450A (en) 1997-10-22 2000-08-08 Rhone-Poulenc Agrochimie Seed specific promoters based on arabidopsis genes
US6232445B1 (en) 1997-10-29 2001-05-15 Sunol Molecular Corporation Soluble MHC complexes and methods of use thereof
WO1999053069A2 (en) 1998-04-09 1999-10-21 E.I. Du Pont De Nemours And Company Cell cycle regulatory proteins cdc2 and pitslre from plants
AU3828099A (en) 1998-05-08 1999-11-29 Consejo Superior De Investigaciones Cientificas Transgenic plant cells expressing a recombinant plant e2f peptide
EP1108031A2 (en) * 1998-09-03 2001-06-20 Pia Vaag 17 kDa FOAM PROTEIN
AU3230200A (en) 1999-02-12 2000-08-29 Pioneer Hi-Bred International, Inc. Transgenic plants with modified expression of the dp protein
GB9923306D0 (en) * 1999-10-01 1999-12-08 Isis Innovation Diagnostic and therapeutic epitope, and transgenic plant
MXPA03009313A (es) * 2001-04-12 2004-11-12 Academish Ziekenhuis Leiden Metodos y medios para uso de receptores de celulas t restringidos por hla-dq y peptidos derivados de prolamina unidos a hla-dq.
EP1332760A1 (en) * 2002-02-04 2003-08-06 Academisch Ziekenhuis Leiden Novel epitopes for celiac disease and autoimmune diseases, methods for detecting those and novel non-antigenic food compounds
US7303871B2 (en) * 2002-02-14 2007-12-04 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for Celiac Sprue
US7320788B2 (en) * 2002-02-14 2008-01-22 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for Celiac Sprue
AU2003234597A1 (en) * 2002-05-14 2003-12-02 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for celiac sprue
US7202216B2 (en) 2002-05-14 2007-04-10 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for celiac sprue
WO2004045392A2 (en) 2002-11-20 2004-06-03 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic method for celiac sprue
GB0212885D0 (en) * 2002-06-05 2002-07-17 Isis Innovation Therapeutic epitopes and uses thereof
US6992916B2 (en) 2003-06-13 2006-01-31 Taiwan Semiconductor Manufacturing Co., Ltd. SRAM cell design with high resistor CMOS gate structure for soft error rate improvement
EP1755639B1 (en) 2004-04-28 2017-08-16 BTG International Limited Epitopes related to coeliac disease
PT2367561E (pt) * 2008-11-30 2015-10-23 Immusant Inc Composições e métodos para o tratamento da doença celíaca
JP6520175B2 (ja) 2015-02-10 2019-05-29 富士通株式会社 無線通信装置、基地局システム及び無線通信装置制御方法

Also Published As

Publication number Publication date
CA2488218C (en) 2020-11-10
EP2292649A2 (en) 2011-03-09
US20180334484A1 (en) 2018-11-22
JP6438423B2 (ja) 2018-12-12
JP2010229138A (ja) 2010-10-14
JP5977293B2 (ja) 2016-08-24
EP2826787B1 (en) 2020-10-28
JP2015052599A (ja) 2015-03-19
CA2488218A1 (en) 2003-12-18
EP2826787A1 (en) 2015-01-21
JP2006512893A (ja) 2006-04-20
JP2016122016A (ja) 2016-07-07
US10053497B2 (en) 2018-08-21
EP1513873A2 (en) 2005-03-16
JP5635302B2 (ja) 2014-12-03
SI1513873T1 (sl) 2014-12-31
WO2003104273A2 (en) 2003-12-18
MXPA04012117A (es) 2005-04-19
HK1205748A1 (en) 2015-12-24
ES2510440T3 (es) 2014-10-21
WO2003104273A3 (en) 2004-09-23
HK1074451A1 (en) 2005-11-11
JP2013101146A (ja) 2013-05-23
AU2003244771A1 (en) 2003-12-22
JP6055689B2 (ja) 2016-12-27
EP2292649A3 (en) 2011-07-06
WO2003104273A9 (en) 2005-01-13
GB0212885D0 (en) 2002-07-17
MX338122B (es) 2016-04-04
CY1115730T1 (el) 2017-01-25
NZ537226A (en) 2008-06-30
JP2015028025A (ja) 2015-02-12
EP1513873B1 (en) 2014-08-13
AU2003244771B2 (en) 2010-01-07
US20060178299A1 (en) 2006-08-10
ZA200409740B (en) 2006-09-27
PT1513873E (pt) 2014-11-04
EP2292649B1 (en) 2014-10-29

Similar Documents

Publication Publication Date Title
DK1513873T3 (da) Terapeutiske epitoper og anvendelser deraf
DK1641822T3 (da) Heterologe il-17-a/f-polypeptider og terapeutiske anvendelser deraf.
DK1572744T3 (da) Immunoglobulinvarianter og deres anvendelser
DK1390389T3 (da) Cripto-blokerende antistoffer og anvendelser deraf
DK1417175T3 (da) Substituerede dihydro-3-halo-1h-pyrazol-5-carboxylater og fremstillingog anvendelse heraf
DK1639007T3 (da) VEGF-fælder og terapeutiske anvendelser deraf
DK1370128T3 (da) Kombineret ballepresse og ballevikler
DK1519770T3 (da) Elektroporesisk indretning og indsprøjtningsapparat
DK1478648T3 (da) Phosphorholdige forbindelser og anvendelser deraf
DK1569712T3 (da) Forbindelsesindretning
DE60326611D1 (de) N und dergleichen
DK2418220T3 (da) Interferon-alpha-antistoffer og anvendelser deraf
NO20041872L (no) Esterforbindelser og medisinsk anvendelse derav
IS7594A (is) Laxófoxifen tafla og húðun hennar
DK1506291T3 (da) Nye phospholipaser og anvendelser deraf
DK1601744T3 (da) Forgasningsapparat og fremgangsmåde
DK1562918T3 (da) Substituerede benzoxazinoner og anvendelser deraf
EP1478761A4 (en) DEGRADATION OF PESTICIDES AND HYDROPHOBIC ESTERIC TOXINS
IS7577A (is) Arómatísk súlfón og læknisfræðileg notkun þeirra
DK1556382T3 (da) 3-Phenylpyridoindolderivater, fremstilling og terapeutisk anvendelse deraf
NO20042693L (no) Kateterpreparat og anvendelser derav
DE60232445D1 (de) Cetirizin und pseudoephedrin enthaltende tablette
NO20050689L (no) Terapeutisk anvendelse
DK1553950T3 (da) Terapeutisk behandling
NO20044106L (no) Omkonstruerte baculoviruser og anvendelse derav