JP2006512292A5 - - Google Patents

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Publication number
JP2006512292A5
JP2006512292A5 JP2004536597A JP2004536597A JP2006512292A5 JP 2006512292 A5 JP2006512292 A5 JP 2006512292A5 JP 2004536597 A JP2004536597 A JP 2004536597A JP 2004536597 A JP2004536597 A JP 2004536597A JP 2006512292 A5 JP2006512292 A5 JP 2006512292A5
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JP
Japan
Prior art keywords
nell
probe
antibody
seq
hybridization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004536597A
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English (en)
Japanese (ja)
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JP2006512292A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/029281 external-priority patent/WO2004024893A2/en
Publication of JP2006512292A publication Critical patent/JP2006512292A/ja
Publication of JP2006512292A5 publication Critical patent/JP2006512292A5/ja
Pending legal-status Critical Current

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JP2004536597A 2002-09-13 2003-09-15 Nell−1による骨石灰化の増進 Pending JP2006512292A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41084602P 2002-09-13 2002-09-13
PCT/US2003/029281 WO2004024893A2 (en) 2002-09-13 2003-09-15 Nell-1 enhanced bone mineralization

Publications (2)

Publication Number Publication Date
JP2006512292A JP2006512292A (ja) 2006-04-13
JP2006512292A5 true JP2006512292A5 (https=) 2009-10-08

Family

ID=31994216

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004536597A Pending JP2006512292A (ja) 2002-09-13 2003-09-15 Nell−1による骨石灰化の増進

Country Status (8)

Country Link
US (2) US20060111313A1 (https=)
EP (1) EP1551978A4 (https=)
JP (1) JP2006512292A (https=)
KR (1) KR20050084550A (https=)
CN (1) CN1867673A (https=)
AU (1) AU2003270736A1 (https=)
CA (1) CA2498751A1 (https=)
WO (1) WO2004024893A2 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7052856B2 (en) 1999-10-05 2006-05-30 The Regents Of The University Of California NELL-1 enhanced bone mineralization
US7884066B2 (en) 1999-10-05 2011-02-08 The Regents Of The University Of California NELL-1 enhanced bone mineralization
US20090060988A1 (en) * 1999-10-05 2009-03-05 Kang Ting Nell-1 enhanced bone mineralization
US7687462B2 (en) 1999-10-05 2010-03-30 The Regents Of The University Of California Composition for promoting cartilage formation or repair comprising a nell gene product and method of treating cartilage-related conditions using such composition
DE602004032107D1 (de) * 2003-02-07 2011-05-19 Univ California Nell-peptidexpressionssysteme und knochenbildende aktivität des nell-peptids
US7691607B2 (en) 2004-02-09 2010-04-06 The Regents Of The University Of California Expression system of NELL peptide
US20060053503A1 (en) * 2004-07-30 2006-03-09 Ut-Battelle, Llc Cranial and vertebral defects associated with loss-of-function of Nell
EP1851237A4 (en) * 2005-02-16 2009-01-07 Univ California PHARMACEUTICAL COMPOSITIONS FOR TREATING OR PREVENTING BONE DISORDERS
CA2699597C (en) * 2007-09-28 2016-10-11 Ut-Battelle, Llc Treatment of cardiovascular disorders using the cell differentiation signaling protein nell1
JP2010540557A (ja) * 2007-09-28 2010-12-24 ユーティー−バッテル・エルエルシー 細胞シグナル伝達タンパク質nell1を用いた、創傷治癒及び筋再生の促進方法
EP2322604A4 (en) * 2008-08-04 2014-01-08 Univ Showa PROCESS FOR REGULATING THE REGENERATION OF TISSUE OR DAMAGE BZW. ABNORMAL SHARING OF AN ORGAN ON THE BASIS OF NELL-1
CA2739608A1 (en) * 2008-10-07 2010-04-15 The Regents Of The University Of California Recombinant nell protein production
US20110002893A1 (en) * 2008-11-03 2011-01-06 Ut-Battelle, Llc Diagnosis and treatment of congenital heart defects using nell1
CA2756168A1 (en) 2009-03-25 2010-09-30 Kang Ting Isoform nell-1 peptide
WO2015082716A1 (en) * 2013-12-06 2015-06-11 Novimmune S.A. Anti-tlr4 antibodies and methods of use thereof
US10752663B2 (en) 2016-08-29 2020-08-25 NellOne Therapeutics, Inc. Methods and compositions for regenerating tissues
CN116763987B (zh) * 2023-05-05 2025-08-22 吉林大学 一种侧枝改性的Gelma水凝胶的制备方法及其应用
CN116768996B (zh) * 2023-05-30 2024-09-06 华南农业大学 一种形成素蛋白基因OsFH2在植物育种调控中的应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4394370A (en) * 1981-09-21 1983-07-19 Jefferies Steven R Bone graft material for osseous defects and method of making same
US4409332A (en) * 1982-01-12 1983-10-11 Jefferies Steven R Collagen-enzyme conjugates that exhibit no inflammatory response and method for making the same
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5674844A (en) * 1991-03-11 1997-10-07 Creative Biomolecules, Inc. Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
US5674725A (en) * 1991-07-11 1997-10-07 British Technology Group Limited Implant materials having a phosphatase and an organophosphorus compound for in vivo mineralization of bone
US5385887A (en) * 1993-09-10 1995-01-31 Genetics Institute, Inc. Formulations for delivery of osteogenic proteins
US5942496A (en) * 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
US5763416A (en) * 1994-02-18 1998-06-09 The Regent Of The University Of Michigan Gene transfer into bone cells and tissues
US6083690A (en) * 1995-06-02 2000-07-04 Osteoscreen, Inc. Methods and compositions for identifying osteogenic agents
US6352972B1 (en) * 1995-06-06 2002-03-05 Marcel E. Nimni Bone morphogenetic proteins and their use in bone growth
US6008208A (en) * 1995-10-23 1999-12-28 Osteoscreen, Inc. Compositions and methods for treating bone deficit conditions
US6048964A (en) * 1995-12-12 2000-04-11 Stryker Corporation Compositions and therapeutic methods using morphogenic proteins and stimulatory factors
US6200606B1 (en) * 1996-01-16 2001-03-13 Depuy Orthopaedics, Inc. Isolation of precursor cells from hematopoietic and nonhematopoietic tissues and their use in vivo bone and cartilage regeneration
US6005088A (en) * 1996-03-19 1999-12-21 Otsuka Pharmaceutical Co., Ltd. Human NPIK gene
US6077987A (en) * 1997-09-04 2000-06-20 North Shore-Long Island Jewish Research Institute Genetic engineering of cells to enhance healing and tissue regeneration
US6462019B1 (en) * 1998-07-10 2002-10-08 Osteoscreen, Inc. Inhibitors of proteasomal activity and production for stimulating bone growth
US7052856B2 (en) * 1999-10-05 2006-05-30 The Regents Of The University Of California NELL-1 enhanced bone mineralization
GB0011356D0 (en) * 2000-05-12 2000-06-28 Univ Nottingham Trent Medical implant materials

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