JP2006509523A5 - - Google Patents
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- Publication number
- JP2006509523A5 JP2006509523A5 JP2004560854A JP2004560854A JP2006509523A5 JP 2006509523 A5 JP2006509523 A5 JP 2006509523A5 JP 2004560854 A JP2004560854 A JP 2004560854A JP 2004560854 A JP2004560854 A JP 2004560854A JP 2006509523 A5 JP2006509523 A5 JP 2006509523A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- cells
- alphavirus
- virus
- alphavirus replicon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43305802P | 2002-12-13 | 2002-12-13 | |
| US43329902P | 2002-12-13 | 2002-12-13 | |
| US60/433,299 | 2002-12-13 | ||
| US60/433,058 | 2002-12-13 | ||
| PCT/US2003/039723 WO2004055166A2 (en) | 2002-12-13 | 2003-12-12 | Multi-antigenic alphavirus replicon particles and methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006509523A JP2006509523A (ja) | 2006-03-23 |
| JP2006509523A5 true JP2006509523A5 (cg-RX-API-DMAC7.html) | 2007-02-08 |
| JP4991108B2 JP4991108B2 (ja) | 2012-08-01 |
Family
ID=32600124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004560854A Expired - Lifetime JP4991108B2 (ja) | 2002-12-13 | 2003-12-12 | 多抗原性アルファウイルス・レプリコン粒子及び方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20040208848A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1585812B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4991108B2 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2003297039B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2509973C (cg-RX-API-DMAC7.html) |
| DK (1) | DK1585812T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2618309T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2004055166A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6783939B2 (en) * | 2000-07-07 | 2004-08-31 | Alphavax, Inc. | Alphavirus vectors and virosomes with modified HIV genes for use in vaccines |
| WO2003023026A1 (en) * | 2001-09-06 | 2003-03-20 | Alphavax, Inc. | Alphavirus replicon vector systems |
| AU2003297039B2 (en) | 2002-12-13 | 2009-03-05 | Alphavax, Inc. | Multi-antigenic alphavirus replicon particles and methods |
| EP1608762B1 (en) | 2003-03-20 | 2014-01-08 | Alphavax, Inc. | Improved alphavirus replicons and helper constructs |
| US7541038B2 (en) * | 2003-06-05 | 2009-06-02 | Wyeth Holdings Corporation | Fusogenic, self-propagating blebs as immunogenic compositions |
| PT1651666E (pt) | 2003-07-11 | 2009-08-28 | Alphavax Inc | Vacinas de citomegalovírus à base de alfavírus |
| PT1751289E (pt) | 2004-05-18 | 2009-03-31 | Alphavax Inc | Vectores de alfavirais derivados da tc-83, partículas e métodos |
| US20090104226A1 (en) * | 2004-05-21 | 2009-04-23 | Novartis Vaccines And Diagnostics Inc. | Alphavirus Vectors for Respiratory Pathogen Vaccines |
| US20050287068A1 (en) * | 2004-06-17 | 2005-12-29 | Bot Adrian I | Efficacy of active immunotherapy by integrating diagnostic with therapeutic methods |
| AU2005327198B2 (en) * | 2004-07-09 | 2011-03-31 | University Of North Carolina At Chapel Hill | Viral adjuvants |
| EP1856250B1 (en) * | 2005-02-15 | 2013-07-24 | The University of North Carolina At Chapel Hill | New live virus vaccines |
| AU2007342333B2 (en) | 2006-09-12 | 2013-02-28 | Alphavax, Inc. | Alphavirus replicon particles encoding IL- 12 as immunological adjuvants |
| US20090022760A1 (en) * | 2006-09-12 | 2009-01-22 | Alphavax | Alphavirus Replicon Particles Matched to Protein Antigens as Immunological Adjuvants |
| DK2947149T3 (en) * | 2007-06-21 | 2018-06-06 | Alphavax Inc | ALPHAVIRUS REPLICATION PARTICLES FOR USE IN VACCINATION |
| AU2010234362B2 (en) * | 2009-04-08 | 2015-11-26 | Alphavax, Inc. | Alphavirus replicon particles expressing TRP2 |
| AU2015249175A1 (en) * | 2009-04-08 | 2015-12-10 | Alphavax, Inc. | Alphavirus Replicon Particles Expressing TRP2 |
| CN103153284B (zh) | 2010-07-06 | 2015-11-25 | 诺华股份有限公司 | 含有其pKa值有利于RNA递送的脂质的脂质体 |
| PT3243526T (pt) | 2010-07-06 | 2020-03-04 | Glaxosmithkline Biologicals Sa | Distribuição de arn para despoletar múltiplas vias imunitárias |
| US10487332B2 (en) | 2010-07-06 | 2019-11-26 | Glaxosmithkline Biologicals Sa | Immunisation of large mammals with low doses of RNA |
| JP5911870B2 (ja) | 2010-08-31 | 2016-04-27 | ノバルティス アーゲー | 免疫原をコードするrnaの送達のためのpeg化リポソーム |
| KR102266691B1 (ko) * | 2010-10-11 | 2021-06-23 | 노파르티스 아게 | 항원 전달 플랫폼 |
| US10004797B2 (en) | 2010-10-27 | 2018-06-26 | Harrisvaccines, Inc. | Method of rapidly producing improved vaccines for animals |
| US20120107355A1 (en) | 2010-10-27 | 2012-05-03 | Harrisvaccines, Inc. | Method of rapidly producing improved vaccines for animals |
| US8822427B2 (en) | 2010-10-27 | 2014-09-02 | Harrisvaccines | Methods and compositions to protect aquatic invertebrates from disease |
| JP2014522842A (ja) * | 2011-07-06 | 2014-09-08 | ノバルティス アーゲー | 免疫原性組み合わせ組成物およびその使用 |
| BR112014008694A2 (pt) * | 2011-10-11 | 2017-06-20 | Novartis Ag | moléculas de ácido nucleico policistrônico recombinante |
| US20140348863A1 (en) * | 2011-10-12 | 2014-11-27 | Alessia Bianchi | Cmv antigens and uses thereof |
| AU2014204826A1 (en) * | 2013-01-10 | 2015-07-09 | Seqirus UK Limited | Influenza virus immunogenic compositions and uses thereof |
| US10174317B2 (en) | 2014-02-13 | 2019-01-08 | Synthetic Genomics, Inc. | Recombinant RNA particles and methods of use |
| US10611800B2 (en) | 2016-03-11 | 2020-04-07 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| KR102945203B1 (ko) | 2017-05-08 | 2026-03-31 | 시애틀 프로젝트 코포레이션 | 알파바이러스 신생항원 벡터 |
| KR102823029B1 (ko) | 2017-12-20 | 2025-06-20 | 브이엘피 테라퓨틱스 인코포레이티드 | 알파바이러스 레플리콘 입자 |
| KR20210090650A (ko) | 2018-11-07 | 2021-07-20 | 그릿스톤 바이오, 인코포레이티드 | 알파바이러스 신생항원 벡터 및 인터페론 억제제 |
| US11629172B2 (en) | 2018-12-21 | 2023-04-18 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| SG11202113187WA (en) | 2019-05-30 | 2021-12-30 | Gritstone Bio Inc | Modified adenoviruses |
| TWI891771B (zh) | 2020-04-17 | 2025-08-01 | 美商Vlp醫療股份有限公司 | 冠狀病毒疫苗 |
| MX2022013638A (es) | 2020-04-30 | 2023-01-24 | Vlp Therapeutics Inc | Inmunoterapia con citocina. |
| TWI871709B (zh) | 2020-06-21 | 2025-02-01 | 美商輝瑞股份有限公司 | 人巨細胞病毒糖蛋白B(gB)多肽 |
| IL300026A (en) | 2020-08-06 | 2023-03-01 | Gritstone Bio Inc | Multiepitope vaccine cassettes |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CA1247080A (en) * | 1983-03-08 | 1988-12-20 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| US4650764A (en) * | 1983-04-12 | 1987-03-17 | Wisconsin Alumni Research Foundation | Helper cell |
| US5091309A (en) * | 1986-01-16 | 1992-02-25 | Washington University | Sindbis virus vectors |
| NZ225583A (en) * | 1987-08-06 | 1991-07-26 | Merck & Co Inc | Process for purifying hepatitis a virions (hav) |
| US5217879A (en) * | 1989-01-12 | 1993-06-08 | Washington University | Infectious Sindbis virus vectors |
| US5185440A (en) * | 1989-06-20 | 1993-02-09 | North Carolina State University | cDNA clone coding for Venezuelan equine encephalitis virus and attenuating mutations thereof |
| SE9003978D0 (sv) * | 1990-12-13 | 1990-12-13 | Henrik Garoff | Dna expressionssystem baserade paa ett virus replikon |
| US6770283B1 (en) * | 1990-12-13 | 2004-08-03 | Bioption Ab | DNA expression systems based on alphaviruses |
| WO1994017813A1 (en) * | 1993-02-08 | 1994-08-18 | Paravax, Inc. | Defective sindbis virus vectors that express toxoplasma gondii p30 antigens |
| US20020102273A1 (en) * | 1995-08-08 | 2002-08-01 | Robert B. Grieve | Use of alphavirus expression vectors to produce parasite anitgens |
| WO1995007994A2 (en) | 1993-09-15 | 1995-03-23 | Viagene, Inc. | Recombinant alphavirus vectors |
| US6015686A (en) * | 1993-09-15 | 2000-01-18 | Chiron Viagene, Inc. | Eukaryotic layered vector initiation systems |
| SE9401091D0 (sv) | 1994-03-31 | 1994-03-31 | Bioption Ab | Alphavirus cDNA vectors |
| SE9401709D0 (sv) * | 1994-05-18 | 1994-05-18 | Mathilda Sjoeberg | Improved alphavirus vectors for expression of heterologous DNA |
| US6309642B1 (en) * | 1997-04-28 | 2001-10-30 | The Research And Development Institute, Inc. | Peptides which mimic candida carbohydrate epitopes and their use in a vaccine |
| US5505947A (en) | 1994-05-27 | 1996-04-09 | The University Of North Carolina At Chapel Hill | Attenuating mutations in Venezuelan Equine Encephalitis virus |
| IL113817A (en) * | 1994-06-30 | 2001-03-19 | Merck & Co Inc | Polynucleotide vaccne for papillomavirus |
| WO1996017072A2 (en) | 1994-11-30 | 1996-06-06 | Chiron Viagene, Inc. | Recombinant alphavirus vectors |
| US5703057A (en) | 1995-04-07 | 1997-12-30 | Board Of Regents The University Of Texas System | Expression library immunization |
| US5792462A (en) * | 1995-05-23 | 1998-08-11 | University Of North Carolina At Chapel Hill | Alphavirus RNA replicon systems |
| US5639650A (en) | 1995-05-23 | 1997-06-17 | The University Of North Carolina At Chapel Hill | cDNA clone for South African Arbovirus No. 86 |
| US5840839A (en) * | 1996-02-09 | 1998-11-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein |
| US6451592B1 (en) * | 1996-04-05 | 2002-09-17 | Chiron Corporation | Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis |
| US5853719A (en) * | 1996-04-30 | 1998-12-29 | Duke University | Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA |
| JP2000514290A (ja) * | 1996-07-01 | 2000-10-31 | ローヌ―プーラン・ロレ・エス・アー | 組換えアデノウイルスの製造方法 |
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| US5827658A (en) | 1996-08-09 | 1998-10-27 | The United States Of America As Reprsented By The Department Of Health And Human Services | Isolation of amplified genes via cDNA subtractive hybridization |
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| US5811407A (en) * | 1997-02-19 | 1998-09-22 | The University Of North Carolina At Chapel Hill | System for the in vivo delivery and expression of heterologous genes in the bone marrow |
| US5958738A (en) | 1997-03-24 | 1999-09-28 | Roche Diagnostics Corporation | Procedure for subtractive hybridization and difference analysis |
| US6261570B1 (en) * | 1997-05-20 | 2001-07-17 | The United States Of America As Represented By The Secretary Of The Army | Live attenuated virus vaccines for western equine encephalitis virus, eastern equine encephalitis virus, and venezuelan equine encephalitis virus IE and IIIA variants |
| AUPO856097A0 (en) | 1997-08-14 | 1997-09-04 | Commonwealth Scientific And Industrial Research Organisation | Vector |
| US6197502B1 (en) * | 1997-11-17 | 2001-03-06 | Cytos Biotechnology Ag | Expression cloning processes for the discovery characterization, and isolation of genes encoding polypeptides with a predetermined property |
| GB9804632D0 (en) * | 1998-03-05 | 1998-04-29 | Cantab Pharma Res | Virus preparations and methods |
| CA2327835C (en) | 1998-04-08 | 2010-09-21 | University Of North Carolina At Chapel Hill | Methods and modified cells for the treatment of cancer |
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| US6783939B2 (en) * | 2000-07-07 | 2004-08-31 | Alphavax, Inc. | Alphavirus vectors and virosomes with modified HIV genes for use in vaccines |
| WO2002020721A2 (en) | 2000-09-07 | 2002-03-14 | University Of North Carolina At Chapel Hill | Vectors derived from south african arbovirus no. 86 |
| AU2002305914A1 (en) * | 2001-01-12 | 2002-10-21 | Chiron Corporation | Nucleic acid mucosal immunization |
| CA2448066A1 (en) * | 2001-05-31 | 2002-12-12 | Chiron Corporation | Chimeric alphavirus replicon particles |
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| WO2004055161A2 (en) * | 2002-12-12 | 2004-07-01 | The Board Of Regents Of The University Of Texas System | Large scale production of packaged alphavirus replicons |
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| AU2003297039B2 (en) | 2002-12-13 | 2009-03-05 | Alphavax, Inc. | Multi-antigenic alphavirus replicon particles and methods |
| EP1608762B1 (en) | 2003-03-20 | 2014-01-08 | Alphavax, Inc. | Improved alphavirus replicons and helper constructs |
| US20060099587A1 (en) * | 2003-06-20 | 2006-05-11 | Johnston Robert E | Alphavirus vectors having attentuated virion structural proteins |
| PT1651666E (pt) * | 2003-07-11 | 2009-08-28 | Alphavax Inc | Vacinas de citomegalovírus à base de alfavírus |
| PT1751289E (pt) | 2004-05-18 | 2009-03-31 | Alphavax Inc | Vectores de alfavirais derivados da tc-83, partículas e métodos |
| AU2010234362B2 (en) * | 2009-04-08 | 2015-11-26 | Alphavax, Inc. | Alphavirus replicon particles expressing TRP2 |
-
2003
- 2003-12-12 AU AU2003297039A patent/AU2003297039B2/en not_active Expired
- 2003-12-12 EP EP03813432.6A patent/EP1585812B1/en not_active Expired - Lifetime
- 2003-12-12 JP JP2004560854A patent/JP4991108B2/ja not_active Expired - Lifetime
- 2003-12-12 DK DK03813432.6T patent/DK1585812T3/en active
- 2003-12-12 US US10/735,601 patent/US20040208848A1/en not_active Abandoned
- 2003-12-12 ES ES03813432.6T patent/ES2618309T3/es not_active Expired - Lifetime
- 2003-12-12 CA CA2509973A patent/CA2509973C/en not_active Expired - Lifetime
- 2003-12-12 WO PCT/US2003/039723 patent/WO2004055166A2/en not_active Ceased
-
2008
- 2008-05-06 US US12/116,031 patent/US8617533B2/en not_active Expired - Fee Related
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