JP2006507004A - プロテアーゼ酵素の検出 - Google Patents

プロテアーゼ酵素の検出 Download PDF

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Publication number
JP2006507004A
JP2006507004A JP2004555661A JP2004555661A JP2006507004A JP 2006507004 A JP2006507004 A JP 2006507004A JP 2004555661 A JP2004555661 A JP 2004555661A JP 2004555661 A JP2004555661 A JP 2004555661A JP 2006507004 A JP2006507004 A JP 2006507004A
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JP
Japan
Prior art keywords
labeled
protease
inhibitor
capture
complex
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Pending
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JP2004555661A
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English (en)
Japanese (ja)
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JP2006507004A5 (enExample
Inventor
ピーター、エイ.クラウセン
ジェイムズ、ジー.レイザー
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Marligen Biosciences Inc
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Marligen Biosciences Inc
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Publication date
Application filed by Marligen Biosciences Inc filed Critical Marligen Biosciences Inc
Publication of JP2006507004A publication Critical patent/JP2006507004A/ja
Publication of JP2006507004A5 publication Critical patent/JP2006507004A5/ja
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2004555661A 2002-11-22 2003-11-24 プロテアーゼ酵素の検出 Pending JP2006507004A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42828602P 2002-11-22 2002-11-22
PCT/US2003/037514 WO2004048935A2 (en) 2002-11-22 2003-11-24 Detection of protease enzymes

Publications (2)

Publication Number Publication Date
JP2006507004A true JP2006507004A (ja) 2006-03-02
JP2006507004A5 JP2006507004A5 (enExample) 2007-01-18

Family

ID=32393376

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004555661A Pending JP2006507004A (ja) 2002-11-22 2003-11-24 プロテアーゼ酵素の検出

Country Status (6)

Country Link
US (1) US20060134774A1 (enExample)
EP (1) EP1567677A4 (enExample)
JP (1) JP2006507004A (enExample)
AU (1) AU2003295863A1 (enExample)
CA (1) CA2506197A1 (enExample)
WO (1) WO2004048935A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008136520A1 (ja) * 2007-05-08 2008-11-13 B-Core Inc. 光学式認識コードのマーキング方法及び装置並びに関連方法及び関連装置
JP2009532058A (ja) * 2006-04-06 2009-09-10 キンバリー クラーク ワールドワイド インコーポレイテッド 酵素検出技術

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7329506B2 (en) * 2004-12-03 2008-02-12 Rutgers, The State University Apparatuses and methods for determining protease activity
GB2435511A (en) 2006-02-23 2007-08-29 Mologic Ltd Protease detection
GB2435510A (en) 2006-02-23 2007-08-29 Mologic Ltd Enzyme detection product and methods
GB2435512A (en) 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
GB2437311A (en) * 2006-04-07 2007-10-24 Mologic Ltd A protease detection product
CN102062735B (zh) * 2009-11-18 2013-09-18 江苏迈迪基因生物科技有限公司 急性冠状动脉综合症的生物标志物诊断试剂盒
NZ603004A (en) * 2010-04-08 2014-05-30 Symansis Ltd Assay system
WO2013148498A1 (en) 2012-03-27 2013-10-03 Ventana Medical Systems, Inc. Signaling conjugates and methods of use
CN105874078A (zh) * 2013-11-26 2016-08-17 富鲁达加拿大公司 使用元素分析的多重酶测定
CN105021819B (zh) * 2014-04-28 2017-05-03 中国科学院苏州纳米技术与纳米仿生研究所 荧光纳米磁性粒子‑多肽底物复合体及其制备方法
EP3201311A4 (en) 2014-09-29 2018-06-20 Chipcare Corporation A device for optical detection of cells comprising a cartridge and fluidic chip and methods thereof
US10466159B2 (en) * 2014-11-28 2019-11-05 Chipcare Corporation Multiplex bead array assay
WO2019046288A1 (en) * 2017-08-31 2019-03-07 Massachusetts Institute Of Technology MULTIPLEX COMPOSITIONS AND ASSAYS FOR CHARACTERIZING ACTIVE PROTEASE AND THEIR INHIBITORS
CN112379103A (zh) * 2020-11-04 2021-02-19 上海赛罕生物技术有限公司 一种抗蛋白酶3抗体测定试剂盒及其测定方法
CN113189074A (zh) * 2021-05-11 2021-07-30 深圳技术大学 一种超高灵敏度的蛋白酶数字检测方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753875A (en) * 1981-11-02 1988-06-28 Ryan James W Method for assaying proteases with tagged proteinaceous inhibitors
DE3322373C2 (de) * 1983-05-19 1986-12-04 Ioannis Dr. 3000 Hannover Tripatzis Testmittel und Verfahren zum Nachweis von Antigenen und/oder Antikörpern
WO1995034538A2 (en) * 1994-06-10 1995-12-21 Universitaire Instelling Antwerpen Purification of serine proteases and synthetic inhibitors thereof
US6297062B1 (en) * 1996-03-07 2001-10-02 Bio-Magnetics Ltd. Separation by magnetic particles
US5955431A (en) * 1997-02-05 1999-09-21 Brigham And Women's Hospital, Inc. Mast cell protease peptide inhibitors
JP2000033712A (ja) * 1997-09-30 2000-02-02 Seiko Epson Corp マイクロセンサーデバイス作成方法及びそれを用いた液体機能評価方法
DE19820328A1 (de) * 1998-05-07 1999-11-11 Roche Diagnostics Gmbh Verfahren und Reagenz zum Nachweis apoptotischer Zellen bzw. einer bei Apoptose aktivierten Protease
US6440659B1 (en) * 2000-04-19 2002-08-27 Washington University Inhibitors of retroviral protease as inducers of reversible insulin resistance in vitro and in vivo

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009532058A (ja) * 2006-04-06 2009-09-10 キンバリー クラーク ワールドワイド インコーポレイテッド 酵素検出技術
WO2008136520A1 (ja) * 2007-05-08 2008-11-13 B-Core Inc. 光学式認識コードのマーキング方法及び装置並びに関連方法及び関連装置

Also Published As

Publication number Publication date
CA2506197A1 (en) 2004-06-10
EP1567677A4 (en) 2007-04-18
EP1567677A2 (en) 2005-08-31
AU2003295863A1 (en) 2004-06-18
WO2004048935A3 (en) 2004-08-26
US20060134774A1 (en) 2006-06-22
WO2004048935A2 (en) 2004-06-10

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