CA2506197A1 - Detection of protease enzymes - Google Patents
Detection of protease enzymes Download PDFInfo
- Publication number
- CA2506197A1 CA2506197A1 CA002506197A CA2506197A CA2506197A1 CA 2506197 A1 CA2506197 A1 CA 2506197A1 CA 002506197 A CA002506197 A CA 002506197A CA 2506197 A CA2506197 A CA 2506197A CA 2506197 A1 CA2506197 A1 CA 2506197A1
- Authority
- CA
- Canada
- Prior art keywords
- labeled
- protease
- inhibitor
- bead
- capture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42828602P | 2002-11-22 | 2002-11-22 | |
| US60/428,286 | 2002-11-22 | ||
| PCT/US2003/037514 WO2004048935A2 (en) | 2002-11-22 | 2003-11-24 | Detection of protease enzymes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2506197A1 true CA2506197A1 (en) | 2004-06-10 |
Family
ID=32393376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002506197A Abandoned CA2506197A1 (en) | 2002-11-22 | 2003-11-24 | Detection of protease enzymes |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20060134774A1 (enExample) |
| EP (1) | EP1567677A4 (enExample) |
| JP (1) | JP2006507004A (enExample) |
| AU (1) | AU2003295863A1 (enExample) |
| CA (1) | CA2506197A1 (enExample) |
| WO (1) | WO2004048935A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102062735B (zh) * | 2009-11-18 | 2013-09-18 | 江苏迈迪基因生物科技有限公司 | 急性冠状动脉综合症的生物标志物诊断试剂盒 |
| CN112379103A (zh) * | 2020-11-04 | 2021-02-19 | 上海赛罕生物技术有限公司 | 一种抗蛋白酶3抗体测定试剂盒及其测定方法 |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7329506B2 (en) * | 2004-12-03 | 2008-02-12 | Rutgers, The State University | Apparatuses and methods for determining protease activity |
| GB2435511A (en) | 2006-02-23 | 2007-08-29 | Mologic Ltd | Protease detection |
| GB2435510A (en) | 2006-02-23 | 2007-08-29 | Mologic Ltd | Enzyme detection product and methods |
| GB2435512A (en) | 2006-02-23 | 2007-08-29 | Mologic Ltd | A binding assay and assay device |
| US8758989B2 (en) * | 2006-04-06 | 2014-06-24 | Kimberly-Clark Worldwide, Inc. | Enzymatic detection techniques |
| GB2437311A (en) * | 2006-04-07 | 2007-10-24 | Mologic Ltd | A protease detection product |
| WO2008136520A1 (ja) * | 2007-05-08 | 2008-11-13 | B-Core Inc. | 光学式認識コードのマーキング方法及び装置並びに関連方法及び関連装置 |
| NZ603004A (en) * | 2010-04-08 | 2014-05-30 | Symansis Ltd | Assay system |
| WO2013148498A1 (en) | 2012-03-27 | 2013-10-03 | Ventana Medical Systems, Inc. | Signaling conjugates and methods of use |
| CN105874078A (zh) * | 2013-11-26 | 2016-08-17 | 富鲁达加拿大公司 | 使用元素分析的多重酶测定 |
| CN105021819B (zh) * | 2014-04-28 | 2017-05-03 | 中国科学院苏州纳米技术与纳米仿生研究所 | 荧光纳米磁性粒子‑多肽底物复合体及其制备方法 |
| EP3201311A4 (en) | 2014-09-29 | 2018-06-20 | Chipcare Corporation | A device for optical detection of cells comprising a cartridge and fluidic chip and methods thereof |
| US10466159B2 (en) * | 2014-11-28 | 2019-11-05 | Chipcare Corporation | Multiplex bead array assay |
| WO2019046288A1 (en) * | 2017-08-31 | 2019-03-07 | Massachusetts Institute Of Technology | MULTIPLEX COMPOSITIONS AND ASSAYS FOR CHARACTERIZING ACTIVE PROTEASE AND THEIR INHIBITORS |
| CN113189074A (zh) * | 2021-05-11 | 2021-07-30 | 深圳技术大学 | 一种超高灵敏度的蛋白酶数字检测方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4753875A (en) * | 1981-11-02 | 1988-06-28 | Ryan James W | Method for assaying proteases with tagged proteinaceous inhibitors |
| DE3322373C2 (de) * | 1983-05-19 | 1986-12-04 | Ioannis Dr. 3000 Hannover Tripatzis | Testmittel und Verfahren zum Nachweis von Antigenen und/oder Antikörpern |
| WO1995034538A2 (en) * | 1994-06-10 | 1995-12-21 | Universitaire Instelling Antwerpen | Purification of serine proteases and synthetic inhibitors thereof |
| US6297062B1 (en) * | 1996-03-07 | 2001-10-02 | Bio-Magnetics Ltd. | Separation by magnetic particles |
| US5955431A (en) * | 1997-02-05 | 1999-09-21 | Brigham And Women's Hospital, Inc. | Mast cell protease peptide inhibitors |
| JP2000033712A (ja) * | 1997-09-30 | 2000-02-02 | Seiko Epson Corp | マイクロセンサーデバイス作成方法及びそれを用いた液体機能評価方法 |
| DE19820328A1 (de) * | 1998-05-07 | 1999-11-11 | Roche Diagnostics Gmbh | Verfahren und Reagenz zum Nachweis apoptotischer Zellen bzw. einer bei Apoptose aktivierten Protease |
| US6440659B1 (en) * | 2000-04-19 | 2002-08-27 | Washington University | Inhibitors of retroviral protease as inducers of reversible insulin resistance in vitro and in vivo |
-
2003
- 2003-11-24 EP EP03787076A patent/EP1567677A4/en not_active Withdrawn
- 2003-11-24 JP JP2004555661A patent/JP2006507004A/ja active Pending
- 2003-11-24 US US10/535,833 patent/US20060134774A1/en not_active Abandoned
- 2003-11-24 AU AU2003295863A patent/AU2003295863A1/en not_active Abandoned
- 2003-11-24 WO PCT/US2003/037514 patent/WO2004048935A2/en not_active Ceased
- 2003-11-24 CA CA002506197A patent/CA2506197A1/en not_active Abandoned
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102062735B (zh) * | 2009-11-18 | 2013-09-18 | 江苏迈迪基因生物科技有限公司 | 急性冠状动脉综合症的生物标志物诊断试剂盒 |
| CN112379103A (zh) * | 2020-11-04 | 2021-02-19 | 上海赛罕生物技术有限公司 | 一种抗蛋白酶3抗体测定试剂盒及其测定方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1567677A4 (en) | 2007-04-18 |
| EP1567677A2 (en) | 2005-08-31 |
| AU2003295863A1 (en) | 2004-06-18 |
| WO2004048935A3 (en) | 2004-08-26 |
| US20060134774A1 (en) | 2006-06-22 |
| JP2006507004A (ja) | 2006-03-02 |
| WO2004048935A2 (en) | 2004-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |