AU2003295863A1 - Detection of protease enzymes - Google Patents

Detection of protease enzymes Download PDF

Info

Publication number
AU2003295863A1
AU2003295863A1 AU2003295863A AU2003295863A AU2003295863A1 AU 2003295863 A1 AU2003295863 A1 AU 2003295863A1 AU 2003295863 A AU2003295863 A AU 2003295863A AU 2003295863 A AU2003295863 A AU 2003295863A AU 2003295863 A1 AU2003295863 A1 AU 2003295863A1
Authority
AU
Australia
Prior art keywords
labeled
protease
inhibitor
bead
capture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003295863A
Other languages
English (en)
Inventor
James G. Lazar
Peter A. lausen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Marligen Biosciences Inc
Original Assignee
Marligen Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marligen Biosciences Inc filed Critical Marligen Biosciences Inc
Publication of AU2003295863A1 publication Critical patent/AU2003295863A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AU2003295863A 2002-11-22 2003-11-24 Detection of protease enzymes Abandoned AU2003295863A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42828602P 2002-11-22 2002-11-22
US60/428,286 2002-11-22
PCT/US2003/037514 WO2004048935A2 (en) 2002-11-22 2003-11-24 Detection of protease enzymes

Publications (1)

Publication Number Publication Date
AU2003295863A1 true AU2003295863A1 (en) 2004-06-18

Family

ID=32393376

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003295863A Abandoned AU2003295863A1 (en) 2002-11-22 2003-11-24 Detection of protease enzymes

Country Status (6)

Country Link
US (1) US20060134774A1 (enExample)
EP (1) EP1567677A4 (enExample)
JP (1) JP2006507004A (enExample)
AU (1) AU2003295863A1 (enExample)
CA (1) CA2506197A1 (enExample)
WO (1) WO2004048935A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7329506B2 (en) * 2004-12-03 2008-02-12 Rutgers, The State University Apparatuses and methods for determining protease activity
GB2435511A (en) 2006-02-23 2007-08-29 Mologic Ltd Protease detection
GB2435510A (en) 2006-02-23 2007-08-29 Mologic Ltd Enzyme detection product and methods
GB2435512A (en) 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
US8758989B2 (en) * 2006-04-06 2014-06-24 Kimberly-Clark Worldwide, Inc. Enzymatic detection techniques
GB2437311A (en) * 2006-04-07 2007-10-24 Mologic Ltd A protease detection product
WO2008136520A1 (ja) * 2007-05-08 2008-11-13 B-Core Inc. 光学式認識コードのマーキング方法及び装置並びに関連方法及び関連装置
CN102062735B (zh) * 2009-11-18 2013-09-18 江苏迈迪基因生物科技有限公司 急性冠状动脉综合症的生物标志物诊断试剂盒
NZ603004A (en) * 2010-04-08 2014-05-30 Symansis Ltd Assay system
WO2013148498A1 (en) 2012-03-27 2013-10-03 Ventana Medical Systems, Inc. Signaling conjugates and methods of use
CN105874078A (zh) * 2013-11-26 2016-08-17 富鲁达加拿大公司 使用元素分析的多重酶测定
CN105021819B (zh) * 2014-04-28 2017-05-03 中国科学院苏州纳米技术与纳米仿生研究所 荧光纳米磁性粒子‑多肽底物复合体及其制备方法
EP3201311A4 (en) 2014-09-29 2018-06-20 Chipcare Corporation A device for optical detection of cells comprising a cartridge and fluidic chip and methods thereof
US10466159B2 (en) * 2014-11-28 2019-11-05 Chipcare Corporation Multiplex bead array assay
WO2019046288A1 (en) * 2017-08-31 2019-03-07 Massachusetts Institute Of Technology MULTIPLEX COMPOSITIONS AND ASSAYS FOR CHARACTERIZING ACTIVE PROTEASE AND THEIR INHIBITORS
CN112379103A (zh) * 2020-11-04 2021-02-19 上海赛罕生物技术有限公司 一种抗蛋白酶3抗体测定试剂盒及其测定方法
CN113189074A (zh) * 2021-05-11 2021-07-30 深圳技术大学 一种超高灵敏度的蛋白酶数字检测方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753875A (en) * 1981-11-02 1988-06-28 Ryan James W Method for assaying proteases with tagged proteinaceous inhibitors
DE3322373C2 (de) * 1983-05-19 1986-12-04 Ioannis Dr. 3000 Hannover Tripatzis Testmittel und Verfahren zum Nachweis von Antigenen und/oder Antikörpern
WO1995034538A2 (en) * 1994-06-10 1995-12-21 Universitaire Instelling Antwerpen Purification of serine proteases and synthetic inhibitors thereof
US6297062B1 (en) * 1996-03-07 2001-10-02 Bio-Magnetics Ltd. Separation by magnetic particles
US5955431A (en) * 1997-02-05 1999-09-21 Brigham And Women's Hospital, Inc. Mast cell protease peptide inhibitors
JP2000033712A (ja) * 1997-09-30 2000-02-02 Seiko Epson Corp マイクロセンサーデバイス作成方法及びそれを用いた液体機能評価方法
DE19820328A1 (de) * 1998-05-07 1999-11-11 Roche Diagnostics Gmbh Verfahren und Reagenz zum Nachweis apoptotischer Zellen bzw. einer bei Apoptose aktivierten Protease
US6440659B1 (en) * 2000-04-19 2002-08-27 Washington University Inhibitors of retroviral protease as inducers of reversible insulin resistance in vitro and in vivo

Also Published As

Publication number Publication date
CA2506197A1 (en) 2004-06-10
EP1567677A4 (en) 2007-04-18
EP1567677A2 (en) 2005-08-31
WO2004048935A3 (en) 2004-08-26
US20060134774A1 (en) 2006-06-22
JP2006507004A (ja) 2006-03-02
WO2004048935A2 (en) 2004-06-10

Similar Documents

Publication Publication Date Title
US20060134774A1 (en) Detection of protease enzymes
US20030054413A1 (en) Bio-sensing platforms for detection and quantitation of biological molecules
US8114681B2 (en) Highly multiplexed particle-based assays
EP2205974B1 (en) Immobilizing an entity in a desired orientation on a support material
US20160123969A1 (en) Methods, materials, and kits for covalently associating molecular species with a surface of an object
EP3199948B1 (en) Method for detecting target molecule, and kit for use in said method
US20040229284A1 (en) Multiplex analysis of proteins
AU2003226116B2 (en) Detection of DNA-binding proteins
US20220205992A1 (en) Materials and kits relating to association of reporter species and targeting entities with beads
CN101180405A (zh) 酶分析方法
Kenten et al. Assays for high‐throughput screening of E2 and E3 ubiquitin ligases
KR20120045822A (ko) 효소의 활성형의 정성적 및 정량적인 분석방법
US20020055123A1 (en) Screening method for identifying ligands for target proteins
Saha et al. High-Throughput Arginylation Assay in Microplate Format
AU2002329805A1 (en) Bio-sensing platforms for detection and quantitation of biological molecules

Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period