JP2006506413A - 喘息治療のためのタクロリムス（ＦＫ５０６）誘導体とβ２アゴニストとの併用使用 - Google Patents

喘息治療のためのタクロリムス（ＦＫ５０６）誘導体とβ２アゴニストとの併用使用 Download PDF

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Publication number
JP2006506413A
JP2006506413A JP2004549603A JP2004549603A JP2006506413A JP 2006506413 A JP2006506413 A JP 2006506413A JP 2004549603 A JP2004549603 A JP 2004549603A JP 2004549603 A JP2004549603 A JP 2004549603A JP 2006506413 A JP2006506413 A JP 2006506413A
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Japan
Prior art keywords
group
agonist
derivative
asthma
treatment
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JP2004549603A
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English (en)
Japanese (ja)
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JP2006506413A5 (enExample
Inventor
良孝 平山
佳彦 森下
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Astellas Pharma Inc
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Astellas Pharma Inc
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Publication of JP2006506413A publication Critical patent/JP2006506413A/ja
Publication of JP2006506413A5 publication Critical patent/JP2006506413A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2004549603A 2002-11-08 2003-11-04 喘息治療のためのタクロリムス（ＦＫ５０６）誘導体とβ２アゴニストとの併用使用 Withdrawn JP2006506413A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2002952559A AU2002952559A0 (en) 2002-11-08 2002-11-08 New use
PCT/JP2003/014077 WO2004041278A1 (en) 2002-11-08 2003-11-04 Use of tacrolimus (fk506) derivatives combined with beta2-agonists for the treatment of asthma

Publications (2)

Publication Number Publication Date
JP2006506413A true JP2006506413A (ja) 2006-02-23
JP2006506413A5 JP2006506413A5 (enExample) 2006-08-17

Family

ID=28795949

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004549603A Withdrawn JP2006506413A (ja) 2002-11-08 2003-11-04 喘息治療のためのタクロリムス（ＦＫ５０６）誘導体とβ２アゴニストとの併用使用

Country Status (8)

Country Link
US (1) US20060035918A1 (enExample)
EP (1) EP1558249A1 (enExample)
JP (1) JP2006506413A (enExample)
KR (1) KR20050071491A (enExample)
CN (1) CN1691946A (enExample)
AU (1) AU2002952559A0 (enExample)
CA (1) CA2499719A1 (enExample)
WO (1) WO2004041278A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009529543A (ja) * 2006-03-14 2009-08-20 ホールサム バイオファーム ピーティーワイ エルティーディー アレルギー性疾患を治療するための方法および組成物

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2935801A1 (en) 2014-01-13 2015-07-16 Amplyx Pharmaceuticals, Inc. Antifungal compounds
KR101632042B1 (ko) 2014-06-30 2016-06-21 주식회사 인트론바이오테크놀로지 Fk506 유도체를 함유하는 크립토코쿠스 속 곰팡이 및 칸디다 속 곰팡이에 의한 진균 감염을 치료하기 위한 약제학적 조성물 및 그의 용도
KR102134782B1 (ko) * 2018-12-11 2020-07-17 주식회사 인트론바이오테크놀로지 신규 화합물 및 이를 포함하는 신경계 질환 치료용 약학적 조성물
CN113939519B (zh) * 2018-12-11 2025-02-14 莫尔根生物有限公司 促进毛发生长的新化合物及包含它们的组合物
WO2020122609A1 (ko) * 2018-12-11 2020-06-18 주식회사 인트론바이오테크놀로지 신규 화합물 및 이를 포함하는 신경계 질환 치료용 약학적 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE64214B1 (en) * 1989-06-06 1995-07-26 Fujisawa Pharmaceutical Co Macrolides for the treatment of reversible obstructive airways diseases
US5519049A (en) * 1989-06-06 1996-05-21 Fisons Plc Macrolides for the treatment of reversible obstructive airways diseases
AU719613B2 (en) * 1995-09-19 2000-05-11 Astellas Pharma Inc. Aerosol compositions
EP0918461B1 (en) * 1996-07-29 2004-10-27 Paringenix, Inc. Methods of treating asthma with o-desulfated heparin

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009529543A (ja) * 2006-03-14 2009-08-20 ホールサム バイオファーム ピーティーワイ エルティーディー アレルギー性疾患を治療するための方法および組成物

Also Published As

Publication number Publication date
AU2002952559A0 (en) 2002-11-21
KR20050071491A (ko) 2005-07-07
EP1558249A1 (en) 2005-08-03
US20060035918A1 (en) 2006-02-16
CA2499719A1 (en) 2004-05-21
CN1691946A (zh) 2005-11-02
WO2004041278A1 (en) 2004-05-21

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